Pregnant after a Loss

Blood clotting and miscarriage

Hello ladies!

I have recently experienced 2 consecutive early miscarriages. My doctor had my husband and I do various tests and we just got our bloodwork back.  It turns out my homocysteine and protein c levels were low, which means I may have blood clotting issues which may have been a cause in our miscarriages.  We have an appointment next week with a specialist to review these results and determine next steps.

Have any of you experienced this? What did your doctor do for this? I have been reading online and it sounds like many women will go on heparin or lovenox or baby asparin. Has that helped with any of you?  Also, we are TTC and I think I ovulated this week and now I am kind of nervous to get pregnant prior to meeting with the specialist.  For those of you on the blood thinners, do they put you on once you have are actually pregnant, or do the advise you go on before so it is in your system?

Thanks in advance!!!

Re: Blood clotting and miscarriage

  • It completely depends on what mutation you have if any, and whether you have one or both copies of it (hetero or homozyhous).

    I am hetero for both MTHFR and Factor V Leiden. My hematologist told me that about 40% of the population has one of these, so it's very common, and not a big deal. As a precaution though, and since I've had a loss, I'm going to be starting Lovenox soon and I'm doing baby aspirin now. They don't believe these caused my loss but I'm saying better safe than sorry at this point.

    I believe when your homocysteine levels are off then that's more of an indicator than anything that you need to be on anticoagulants- but I thought it was when your levels were too high, not too low. Could be wrong though.

    My OB said that as long as I start by 2nd tri, it should be ok, but your situation might be different than mine b/c I didn't have the homocysteine issue too.

    Good luck!

    BFP #1- 1/16/09- Baby Ava stillborn at 32 weeks, possible cord accident, 7/30/09
    BFP #2- 1/5/10- Baby Jack born at 37w2d, 6lbs 13 oz, 8/24/10
    BFP #3- 7/30/11- Baby Boy Due April 3, 2012
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  • I have a history of blood clots (I had a pulmonary embolism about 10 yrs ago) but I have tested negative for all clotting disorders.  I saw a hematologist before TTC b/c my PE was so long ago- I just wanted everything to be in order.  They told me I would do daily lovenox injections (as a precaution)  once I got a BFP until 36 weeks.  That's just what I'm doing. 

    When is your appointment with the specialist?  I am sure if you get a BFP they will put you on something right away  since they do know you have issues.  I didn't test until I was 5 weeks along, so I went a whole week without Lovenox- so far everything is just fine.

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  • I also have a history of clotting because of a Pulmonary Embolism (niceasstra, thought I was the only one).  I just needed to let my hemotoligist know when I got pg and they put me on lovenox daily after the bloodwork confirmed.  I will be put on Heparin closer to my due date.  This is obviously different than you but if you have any questions about lovenox or heparin, I feel like I'm an expert!!!  haha.
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  • Thank you for sharing your stories! I guess I will wait to find out more when I meet the specialist next week. It is reassuring to hear that there are things that can be done to help this issue.

    Best of luck to everyone!

  • After my second miscarriage my doctor ran tests similar to what you had done to test for clotting issues, such as antiphospholipid syndrome. My tests came back negative, but had they been positive the options I had spoke to her about included baby aspirin and pregnancy safe blood thinners. I have in fact talked to women who have had to use one or the other during pregnancy and were successful.?

    I wish you the best of luck and hope the specialist can give you all the answers you need to have a happy and healthy pregnancy!?

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  • I'm sorry you have to go through this! My OB would never commit that my clotting factor caused my m/cs but after starting the baby aspirin, it seems to be working for me. There are several ladies here on one thinner or another. I hope you get your answers soon.
    Oct 2008 m/c #1 5 weeks, May 2009 m/c #2 4w5d. BFP 6/23/09 EDD 3/8/10!
    You gain strength, courage and confidence by every experience in which you stop to look fear in the face. -Eleanor Roosevelt
    After 1 year of TTC#2 BFP May 2011 m/c #3 4w2d. Off to RE.

    Round 1: Femara + Ovidrel +TI = BFP! EDD 2/20/12
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