Pregnant after a Loss

MTHFR and Succes??

I just found out I have the compound heterozygote MTHFR mutation, waiting to see a perinatologist. My homocysteine levels were normal though. Any of you have this and have healthy pregnancy??

 Thanks.

2 m/c's before DS, 3 m/c's post DS (Jan '12, March'12, May '12) image Baby Birthday Ticker Ticker

Re: MTHFR and Succes??

  • I have it and so far so good this time. I think there are also several women on this board who are homozygous MTHFR and are doing just fine too. Our peri told us that as long as my homocystein levels were normal, we'd be fine with just a baby aspirin a day. Good luck!
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  • imagesurfergirl28:
    I have it and so far so good this time. I think there are also several women on this board who are homozygous MTHFR and are doing just fine too. Our peri told us that as long as my homocystein levels were normal, we'd be fine with just a baby aspirin a day. Good luck!

    That's great news! Thanks SO much for responding and giving me hope! Yes after all the bad news, at least the homocystein levels were normal...I was hoping that would be reassuring.

    2 m/c's before DS, 3 m/c's post DS (Jan '12, March'12, May '12) image Baby Birthday Ticker Ticker
  • i have it and my levels were normal too, i have a whole document of treatments and test the RE or high risk OB should do for you. i was adamant about the lovenox with a bfp as opposed to waiting to start it. don't know if its what helped but here i am and baby is perfect. PM with your email and i'll gladly send it to you
    BFP #1 May 2000 ~ Darren was born Jan 13, 2001 ~ 6lbs 2oz 191/2" ~ 39 wks due to low fluid, otherwise perfect pregnancy
    July 2004 abnormal pap, colposcopy and LEEP procedure ~ paps every 3 months all normal for 1 year
    2006 all clear to start TTC
    HSG Nov 2007 ~ all normal except mild left tube blockage
    BFP #2 Dec 2007 EDD sept 3 ~ missed m/c ~ Feb 14 2008 ~ 9wk 2d D&C
    BFP #3 Apr 2008 EDD Dec 10 ~ ectopic ~ May 2008 ~ 5wk 2d ~ emergency lap surgery, lost left tube
    BFP #4 Jul 2008 EDD May 5 ~ missed m/c ~ Aug 2008 ~ 5wk 2d D&C - trisomy 16
    RPL panel Aug 2008 ~ diagnosed with compound hetero MTHFR
    BFP #5 Nov 2008 EDD Jul 31 ~ blighted Ovum ~ Dec 2008 ~ 4wk 3d ~ natural m/c at home for my birthday
    BFP #6 Feb 2009 EDD Oct 15 ~ 4wk 3d ~ chemical pregnancy ~ Mar 2008
    BFP #7 May 18 2009 ~ Gabriel Michael ~ Jan 19, 2010 ~ 7lbs 2oz 21"
    TTC again since Jan 2011
    BFP #8 Jun 2011 EDD Jan 20 ~ 5wk 6d ~ missed m/c ~ D&C
    July - Hysterscopy removed some polyps, all clear for IUI with clomid
    Aug-Oct - IUI - with Clomid all BFN
    Nov-Jan - IUI - with femara and trigger = BFN
    back to TTC naturally on our own hoping for another miracle.
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  • I also have it, and so far so good.  I am taking aspirin daily and heparin shots 2x daily, to help with clots, but otherwise things are going well.  Good luck to you@
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  • With those of you taking shots, were your homosytein levels normal or hight? Mrsviv, I'll PM you right now. THANK YOU.
    2 m/c's before DS, 3 m/c's post DS (Jan '12, March'12, May '12) image Baby Birthday Ticker Ticker
  • My homocysteine levels were normal, but I'm homozygous MTHFR+. I'm on baby aspirin once a day, folgard 2x a day, lovenox injections 2x a day, and an added oral prometrium 4x a day. Taking it one day at a time, and today I am still pregnant and I love my baby.
    Lilypie Second Birthday tickers Lilypie Pregnancy tickers
  • imagenicobean1:
    My homocysteine levels were normal, but I'm homozygous MTHFR+. I'm on baby aspirin once a day, folgard 2x a day, lovenox injections 2x a day, and an added oral prometrium 4x a day. Taking it one day at a time, and today I am still pregnant and I love my baby.

    Congrats to you!

    2 m/c's before DS, 3 m/c's post DS (Jan '12, March'12, May '12) image Baby Birthday Ticker Ticker
  • Yes... I have the same and am doing well.  I take a baby aspirin every day.

    GL:)

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  • I have homozygous MTHFR (2 of the 'C').  I'm on 4mg of Folic Acid (plus a low dose aspirin) and am currently 37 weeks!  GL! Oh...my homo. levels were normal, so no Lovenox injections.

    Lilypie Second Birthday tickers 1st m/c July 2008, 2nd m/c December 2008, Baby boy born in 2009!, 3rd m/c (c/p) June 2011, 4th m/c September 2011
  • Most people who are hetero for mthfr will do just fine on just baby asprin.  It's a very common mutation.  But some ladies do need extra intervention.  I have both mthfr and factor v leiden and am on a lovenox treatment and so far so good. Also, my doctors said even if my homocysteine levels were normal it wouldn't mean they would stay normal while pregnant.  So that will need to be tested once pregnant.

    Another doctor to possibly consult is a hematologist.  GL!

    After 2 m/cs, dx October 2008 with hetero factor v leiden & mthfr & low progesterone; third time was the charm - BFP 3/19/09 on first cycle of clomid. Baby Birthday Ticker Ticker
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