We had luck with Gripe water so we tried little tummies (the makers of gripe water) gas drops & they're working! Mylicon didn't do very much for Peyton. Its trial & error. I heard Walgreens had some great gas drops too...
not sure which is safer, but DD had terrible tummy & gas problems, and mylicon (target brand) has worked wonders, and the target brand is muchhh cheaper, and its the same stuff!
We use Gripe Water when my son seems to have an upset tummy/reflux issues, and Mylicon when he's super gassy. Both work well for their uses. I'm not a big medicine person and usually prefer to go the more "natural" route so I would rather use Gripe Water more frequently, but my LO's tummy has different ideas. Plus, the GW has a much higher dose and that can be kind of difficult to get into him if he's not interested in eating. You can give the Mylicon up to 12 times a day, and the Gripe Water up to 6 (if I recall correctly).
Re: Gripe water or Mylicon ?