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Inconclusive MaterniT21 Gender Testing

knottieba76481547714804knottieba76481547714804 Newbie
in 2nd Trimester
Hi, anyone else experience inconclusive gender testing via MaterniT21 at 14 weeks and/or at 17 weeks? I’ve had my blood drawn twice and no results each time. Should I be concerned?
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Re: Inconclusive MaterniT21 Gender Testing

  • harpseal135harpseal135 member
    edited August 2022
    Though very rare intersex children are born (sorry but not everyone is born male or female some are born both).  Honestly, wait for your AS in a couple of weeks they may be able to tell if there is a penis or not.  
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  • inthewoods23inthewoods23 member
    What was the percentage of fetal cells found in your blood samples? If that's too low, I believe it can be difficult to determine baby's sex. 
    *TW* History:
    Me: 34 DH: 36 | Together since 2007 | Married July 2016

    TTC #1 since 7.2017
    Dx: low morph (1%), ANA positive, low decidualization score, high TSH and testosterone, histone antibodies

    IUI #1-3 | all BFN
    IVF #1 | 6.11.19 | 24R, 17M, 15F, 6B, PGT-A tested - 5 normal, 3 girls & 2 boys
    FET #1 | 9.10.19 | BFN "I know you, but we've never met. I'm with you, but I don't know your name"
    RPL, Receptiva, & ERA testing | all normal/negative, recommended going on gluten and dairy free diet for next FET
    FET #2 | 3.31.20 | Opted to cancelled due to pandemic, continued diet and tried naturally over the summer
    2nd Opinion with another RE | 8.20.20 | Not immune to measles (received 1 dose); SA results similar to 2 years ago; decided to move forward with FET #2 redo at start of next cycle
    Surprise natural BFP! | 9.22.20 | MC 10.23.20 at 8 weeks
    TTCAL naturally | starting 11.22.20

    Initial consultation with Reproductive Immunologist | 9.14.21
    Decidualization score biopsy | 10.1.21 | abnormal - low score of 1; endometrial scratch recommended and progesterone supplementation
    Saline sono | 10.15.21 | normal
    Bloodwork | 10.21.21 | high TSH, high testosterone, positive for anti-nuclear antibodies and histone antibodies, high protein S, multiple genetic mutations
    BFP! | 11.3.21 | EDD 7.14.22 B) | biopsy provided same effect as endometrial scratch; added supplemental progesterone and estrogen, prednisone, levothyroxine, and MTX Support to maintain pregnancy
    DS born 7.19.22 after induction


    TTC #2 begins 6.2023
    Consultation with RI | 6.6.23
    Saline sono, endometritis biopsy, skin & eye check | all normal
    Labs | high TSH, Factor XIII mutation, high %CD56
    Follow up | 8.8.23 | prescribed metformin, prednisone, plaquenil, and levothyroxine
    Repeat labs after 3 weeks on meds
    Follow up | 11.9.23 | Green light!, increase in prednisone, added lovenox
    Repeat labs in 8 weeks
    Follow up | 1.16.24 | Green light continues
    TTC put on pause indefinitely
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  • bustabucketbustabucket member
    @harpseal135 Why are you sorry some people are born intersex?
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  • WishilivedinfloridaWishilivedinflorida member
    bustabucket said:
    @harpseal135 Why are you sorry some people are born intersex?
    She’s not sorry. It’s an expression, as in, “nature isn’t perfect and not everyone gets a perfect XX or XY baby.” It’s a real possibility. 
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  • harpseal135harpseal135 member
    Wishilivedinflorida said:
    bustabucket said:
    @harpseal135 Why are you sorry some people are born intersex?
    She’s not sorry. It’s an expression, as in, “nature isn’t perfect and not everyone gets a perfect XX or XY baby.” It’s a real possibility. 
    This - sorry to people in society who feel that everyone is born male or female.  Not everyone is despite what closed minded people think. 
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  • bustabucketbustabucket member
    edited August 2022
    Ohhhh, okay, so like: “sorry, but the point is that your attitude is unnecessarily combative?” Like, sarcasm? You’re doing sarcasm?

    Just because someone has questions doesn’t mean they’re ignorant or closed-minded. 
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  • Knottie1455404633Knottie1455404633 member
    edited August 2022
    Yeah not sure why some people on here are so rude it’s just insane 🙄 just because OP asked asked a legit question that, turns out, actually has nothing to do with just sex chromosome differences. anyways, OP, an inconclusive result is due to insufficient fetal fraction typically  meaning they aren’t really picking up much placental dna in your blood sample (doesn’t mean there’s anything wrong with baby this is just normal in some people). Could also be technical error on the lab side but if you’ve had this performed twice I would guess that to be unlikely. If there was a sex chromosome anomaly that they could see as some posters are suggesting, they would report that and not just say “inconclusive.” 
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  • Knottie1455404633Knottie1455404633 member
    edited August 2022
    PPS. people with klinefelters syndrome, Turner syndrome and XYY are NOT intersex, and those are really the only sex chromosome disorders detected by this particular test. You wouldn’t even be able to detect most types of differences of sexual development with this test (and the result would just say normal, not inconclusive). 
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