IUI part 1 complete - 65 million post wash (152 before so much better morph than the SA!) so fingers crossed. Trigger wasn’t bad and I had a .6 temp rise**. I also had some slight ovulation cramping two hours before trigger, but usually I feel way more. I’m wondering if I usually ovulate while awake and this time was during my very crappy sleep or if it was just so much faster this time with the trigger....
**ETA curious as to how fast the trigger may induce ovulation - they didn’t do an ultrasound this morning and I know it can take up to two days so that temp may definitely be a fluke...
It's funny how it's the little things in life that mean the most...not where you live, or what you drive, or the price tag on your clothes... There's no dollar sign on a piece of mind, this I've come to know! *ZBB*
@keikilove a hCG trigger shot will give you positive OPKs in the beginning because they are both glycoproteins. So if your level of hCG is high enough it will turn the OPK positive just like the LH being high enough to turn it positive then it will.
@NYTino24 so glad things went well! That's a great number, too! Thanks for your advice with my craziness yesterday. We got another HIO session in last night, and my temps were elevated again today, so I resumed the progesterone this AM. I also had my usual post-O signs yesterday afternoon, so I am more confident that I O'ed now. My PM OPK was negative, too. Some cycles I get consistently dark OPKs, so I am chalking it up to one of those times. We're doing IUI next cycle so I think while we'll be sad if this is another busted cycle, we know we have help for the next one.
@keikilove thanks for your advice! My RE says the opposite, to take it 3 days after your surge (so that would be about 2-3 days post O for me). I never heard about progesterone interfering with implantation. I have to take it to lengthen my luteal phase, because my lining starts breaking down and I start spotting around 9DPO. I will ask about that when I see my RE again.
@keikilove I was curious after your question and the answers you got and I took an OPK just now (8 days post trigger and 6 days post IUI) and it was positive. There’s no way I’m still Oing a week later... so i feel the trigger/hCG would totally effect the OPKs.
@NYTino24 those are amazing numbers!!!! So glad everything went well and is working out for you!! 🤞🏼🤞🏼
Our TTC Journey
TTC #1: May 2011 BFP: 10/27/2011 | EDD: 6/30/12 DS born 6/28/12 via C/S
TTC #2: September 2018 Me: 36 | DH: 39 Mirena removed 9/13/2018 after 6 years BFP 11/11/2018 | MC @ 5.5 weeks on Thanksgiving July 2019 - Diagnosed with Secondary Unexplained IF August 2019 - 2.5 mg of Letrozole = Never Ovulated so Trigger and IUI were cancelled 9/30/2019 - IUI #1 (5 mg of Letrozole + Trigger) = BFP but Betas showed CP @ 4 weeks 10/28/2019 - IUI #2 (7.5mg of Letrozole + Trigger) = BFN 11/25/2019 - IUI #3 (7.5mg of Letrozole, Trigger + Crinone after IUI) = BFN 12/24/2019 - IUI #4 (7.5mg of Letrozole + Crinone after IUI) = BFN 1/24/2020 - IUI #5 (50mg of Clomid + Trigger + Crinone after IUI) = BFN and an Ovarian Cyst 3/2/2020 - Taking a break to reset/NTNP 11/1/2020 - At peace with where things are in life and are no long actively TTC. Whatever happens will happen and it will all be okay.
@kpearse99 there's some belief that you can use OPK strips as substitutes for HPTs if you don't have one. But maybe that's only true for really high amounts of HCG. 🤷♀️
*TW* History:
Me: 34 DH: 36 | Together since 2007 | Married July 2016
TTC #1 since 7.2017 Dx: low morph (1%), ANA positive, low decidualization score, high TSH and testosterone, histone antibodies
IUI #1-3| all BFN IVF #1 | 6.11.19 | 24R, 17M, 15F, 6B, PGT-A tested - 5 normal, 3 girls & 2 boys FET #1 | 9.10.19 | BFN "I know you, but we've never met. I'm with you, but I don't know your name" RPL, Receptiva, & ERA testing | all normal/negative, recommended going on gluten and dairy free diet for next FET FET #2 | 3.31.20 | Opted to cancelled due to pandemic, continued diet and tried naturally over the summer 2nd Opinion with another RE | 8.20.20 | Not immune to measles (received 1 dose); SA results similar to 2 years ago; decided to move forward with FET #2 redo at start of next cycle Surprise natural BFP! | 9.22.20 | MC 10.23.20 at 8 weeks TTCAL naturally | starting 11.22.20 Initial consultation with Reproductive Immunologist | 9.14.21 Decidualization score biopsy | 10.1.21 | abnormal - low score of 1; endometrial scratch recommended and progesterone supplementation Saline sono | 10.15.21 | normal Bloodwork | 10.21.21 | high TSH, high testosterone, positive for anti-nuclear antibodies and histone antibodies, high protein S, multiple genetic mutations BFP! | 11.3.21 | EDD 7.14.22 | biopsy provided same effect as endometrial scratch; added supplemental progesterone and estrogen, prednisone, levothyroxine, and MTX Support to maintain pregnancy DS born 7.19.22 after induction
TTC #2 begins 6.2023 Consultation with RI | 6.6.23 Saline sono, endometritis biopsy, skin & eye check | all normal Labs | high TSH, Factor XIII mutation, high %CD56 Follow up | 8.8.23 | prescribed metformin, prednisone, plaquenil, and levothyroxine Repeat labs after 3 weeks on meds Follow up | 11.9.23 | Green light!, increase in prednisone, added lovenox Repeat labs in 8 weeks Follow up | 1.16.24 | Green light continues TTC put on pause
@inthewoods23 I’ve read that too... but I’m trying not to get my hopes up. I would think the 250mcg of ovidrel would still be in my system 7 days later... but we shall see in a week.
My boobs started to become tender today (6 dpiui) but they usually start to feel that way a week before AF sooo.... 🤦🏻♀️🤷🏻♀️
Our TTC Journey
TTC #1: May 2011 BFP: 10/27/2011 | EDD: 6/30/12 DS born 6/28/12 via C/S
TTC #2: September 2018 Me: 36 | DH: 39 Mirena removed 9/13/2018 after 6 years BFP 11/11/2018 | MC @ 5.5 weeks on Thanksgiving July 2019 - Diagnosed with Secondary Unexplained IF August 2019 - 2.5 mg of Letrozole = Never Ovulated so Trigger and IUI were cancelled 9/30/2019 - IUI #1 (5 mg of Letrozole + Trigger) = BFP but Betas showed CP @ 4 weeks 10/28/2019 - IUI #2 (7.5mg of Letrozole + Trigger) = BFN 11/25/2019 - IUI #3 (7.5mg of Letrozole, Trigger + Crinone after IUI) = BFN 12/24/2019 - IUI #4 (7.5mg of Letrozole + Crinone after IUI) = BFN 1/24/2020 - IUI #5 (50mg of Clomid + Trigger + Crinone after IUI) = BFN and an Ovarian Cyst 3/2/2020 - Taking a break to reset/NTNP 11/1/2020 - At peace with where things are in life and are no long actively TTC. Whatever happens will happen and it will all be okay.
Re: IF Testing & Treatment week of 9/30-10/6
**ETA curious as to how fast the trigger may induce ovulation - they didn’t do an ultrasound this morning and I know it can take up to two days so that temp may definitely be a fluke...
TTC 9/2016 BFP 12/9/16 EDD 8/21/17 NMC 1/8/16 at 7w6d
TTC 2/2017 BFP 3/6/17 EDD 11/17/17 DS born 11/25/17 via ECS
TTC 12/2018 BFP 6/2/19 EDD 2/12/20 NMC / BO at 7 weeks, low progesterone
TTC 7/2019 BFP 8/21/19 EDD 4/22/20 CP at 5 weeks
TTC 8/19 IUI #1 w/ Clomid + Ovidrel + progesterone BFN, IUI 2 and 3 w/ Letrozole + Ovidrel + progesterone,
IUI 4 Follistim + Ovidrel + progesterone BFP 1/9/20 EDD 9/18/20
AMA, ITP in pregnancy, vWD type II - low Factor VIII, unexplained RPL and secondary infertility
@keikilove a hCG trigger shot will give you positive OPKs in the beginning because they are both glycoproteins. So if your level of hCG is high enough it will turn the OPK positive just like the LH being high enough to turn it positive then it will.
@keikilove thanks for your advice! My RE says the opposite, to take it 3 days after your surge (so that would be about 2-3 days post O for me). I never heard about progesterone interfering with implantation. I have to take it to lengthen my luteal phase, because my lining starts breaking down and I start spotting around 9DPO. I will ask about that when I see my RE again.
BFP: 10/27/2011 | EDD: 6/30/12
DS born 6/28/12 via C/S
TTC #2: September 2018
Me: 36 | DH: 39
Mirena removed 9/13/2018 after 6 years
BFP 11/11/2018 | MC @ 5.5 weeks on Thanksgiving
July 2019 - Diagnosed with Secondary Unexplained IF
August 2019 - 2.5 mg of Letrozole = Never Ovulated so Trigger and IUI were cancelled
9/30/2019 - IUI #1 (5 mg of Letrozole + Trigger) = BFP but Betas showed CP @ 4 weeks
10/28/2019 - IUI #2 (7.5mg of Letrozole + Trigger) = BFN
11/25/2019 - IUI #3 (7.5mg of Letrozole, Trigger + Crinone after IUI) = BFN
12/24/2019 - IUI #4 (7.5mg of Letrozole + Crinone after IUI) = BFN
1/24/2020 - IUI #5 (50mg of Clomid + Trigger + Crinone after IUI) = BFN and an Ovarian Cyst
3/2/2020 - Taking a break to reset/NTNP
11/1/2020 - At peace with where things are in life and are no long actively TTC. Whatever happens will happen and it will all be okay.
TTC #1 since 7.2017
Dx: low morph (1%), ANA positive, low decidualization score, high TSH and testosterone, histone antibodies
IUI #1-3 | all BFN
IVF #1 | 6.11.19 | 24R, 17M, 15F, 6B, PGT-A tested - 5 normal, 3 girls & 2 boys
FET #1 | 9.10.19 | BFN "I know you, but we've never met. I'm with you, but I don't know your name"
RPL, Receptiva, & ERA testing | all normal/negative, recommended going on gluten and dairy free diet for next FET
FET #2 | 3.31.20 | Opted to cancelled due to pandemic, continued diet and tried naturally over the summer
2nd Opinion with another RE | 8.20.20 | Not immune to measles (received 1 dose); SA results similar to 2 years ago; decided to move forward with FET #2 redo at start of next cycle
Surprise natural BFP! | 9.22.20 | MC 10.23.20 at 8 weeks
TTCAL naturally | starting 11.22.20
Initial consultation with Reproductive Immunologist | 9.14.21
Decidualization score biopsy | 10.1.21 | abnormal - low score of 1; endometrial scratch recommended and progesterone supplementation
Saline sono | 10.15.21 | normal
Bloodwork | 10.21.21 | high TSH, high testosterone, positive for anti-nuclear antibodies and histone antibodies, high protein S, multiple genetic mutations
BFP! | 11.3.21 | EDD 7.14.22 | biopsy provided same effect as endometrial scratch; added supplemental progesterone and estrogen, prednisone, levothyroxine, and MTX Support to maintain pregnancy
DS born 7.19.22 after induction
TTC #2 begins 6.2023
Consultation with RI | 6.6.23
Saline sono, endometritis biopsy, skin & eye check | all normal
Labs | high TSH, Factor XIII mutation, high %CD56
Follow up | 8.8.23 | prescribed metformin, prednisone, plaquenil, and levothyroxine
Repeat labs after 3 weeks on meds
Follow up | 11.9.23 | Green light!, increase in prednisone, added lovenox
Repeat labs in 8 weeks
Follow up | 1.16.24 | Green light continues
TTC put on pause
BFP: 10/27/2011 | EDD: 6/30/12
DS born 6/28/12 via C/S
TTC #2: September 2018
Me: 36 | DH: 39
Mirena removed 9/13/2018 after 6 years
BFP 11/11/2018 | MC @ 5.5 weeks on Thanksgiving
July 2019 - Diagnosed with Secondary Unexplained IF
August 2019 - 2.5 mg of Letrozole = Never Ovulated so Trigger and IUI were cancelled
9/30/2019 - IUI #1 (5 mg of Letrozole + Trigger) = BFP but Betas showed CP @ 4 weeks
10/28/2019 - IUI #2 (7.5mg of Letrozole + Trigger) = BFN
11/25/2019 - IUI #3 (7.5mg of Letrozole, Trigger + Crinone after IUI) = BFN
12/24/2019 - IUI #4 (7.5mg of Letrozole + Crinone after IUI) = BFN
1/24/2020 - IUI #5 (50mg of Clomid + Trigger + Crinone after IUI) = BFN and an Ovarian Cyst
3/2/2020 - Taking a break to reset/NTNP
11/1/2020 - At peace with where things are in life and are no long actively TTC. Whatever happens will happen and it will all be okay.