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Re: June 2019 IVF

Hello all! I was encouraged by my certified nurse-midwife, who serves as my gyn, to join as she has had her own personal experience with IF & IVF reported she benefitted from the support. So a little about me…. I am 34 y/o diagnosed with left tubal blockage and my DH is 35 y/o and has morphology and motility challenges. I wanted to try IUI first by my fertility specialist suggested IVF with ICSI due to the motility issue. We have been married for 3 years and TTC for 2 years now. I am currently on BC as of a week, I am scheduled to get bloodwork on the 19th to determine whether or not I can start the injections (menopur and Gonal F) on the 23rd. We have decided to get our embryos tested (PGS)- but the concern/worry is do we rush the results so that we can do a fresh xfer or wait the 10-14 days for the results and do a FET at a later time? My concern is having to prep my body (another round of injections) to receive the embryo. Anyone else experience this worry…please share your thoughts! Thanks and I look forward to going through this journey with you all!


Re: Re: June 2019 IVF

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    From my research, FET tend to lead to better results in many cases because the stim drugs can affect the quality of the hormones needed to keep a pregnancy healthy whereas the FET can allow you to prep your body specifically for being and staying pregnant. My Dr. only does FET for PGS tested embryos, so I didn't have a choice. At my age, I am not willing to risk putting in an abnormal blast. I don't know that they can rush the results? Good luck on your journey!!
    Me: 45yo, DH: 47yo
    3 Daughters (singleton @27yo, ID  Di/Di Twins @34yo)
    Protein S Deficiency (Blood Clotting Disorder), MTHFR & VIT D issue 
    5 MC's:  Blighted Ovum-D&C @ 9wks;  Natural MC @ 7wks; Blighted Ovum-D&C @ 9wks; MC boy-D&C @ 9wks & Chem PG in 2019
    Tubes were tied after my Twins (and now I am old). Remarried and want to give my DH a baby!

    IVF#1 OE June 2019 - ER 6/15/19, 24R, 21M, 20F, 7 6DBlasts Frozen for PGS Testing,
    RESULTS of PGS 4 abnormal girls,  2 abnormal boys, 1 indeterminate girl
    FET#1 OE August 23, 2019 (transferring 1 indeterminate girl & 1 abnormal boy) - BFN
    IVF#2 November 15, 2019 - ER 9R, 9M, 6F, 2 5dBlasts (fresh transfer) and 1 6DBlast frozen for PGS Testing,
    FRESH Transfer: November 20, 2019, 2 5-day blasts transferred!! 
    BFP 8dp5dt on 11/27 - 12/2 on FRER, BETA #1 12/2 - 11.93. BETA #2 12/4: 4.41 ~CHEMICAL PG
    ******************Starting Donor Process
    June 2020: Egg Donor Cycle and Fresh Transfer of 1 embryo in Czech Republic - CANCELLED DUE TO COVID19
    October 2020.  Split Cycle at UFC with a friend (Andrea) I met on the Bump who was also supposed to go to Prague too  
    DE Retrieval 9/26/2020, 26R, 24M, 12 split Cycle, 9 Fertilized + 1 "questionable", PRAYING FOR AT LEAST 5 BLASTS
    10/1/2020: 4 5DBlasts (AA, BB, BC, BC), 10/2/2020: 3 6DBlasts (BB, BB, BC) FOR A TOTAL OF: 7 BLASTS!! THANK YOU GOD!!
    PGS RESULTS: 5 NORMALS! DAY 5: AA BOY, BB GIRL, BC BOY / DAY 6: BB GIRL, BC GIRL
    DE FET October 29, 2020 - CANCELED DUE TO FLUID IN LINING
    DE FET November 16th, 2020 (transferring an PGS normal Hatching AA Boy)
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    My situation is the same as @ladyp0tter in that they freeze all and PGT test them so FETs only.

    I'm actually on day 6 post-ER and I do feel quite back to normal so I think for me I would be able to deal with having a transfer so soon after ER but I know some ladies end up having to deal with OHSS, in which case, a fresh transfer wouldn't be done.

    Waiting does really suck, but your body needs time to heal too. It's the same for those that want lots of kids but need to follow the recommended recovery time before having sex postpartum.
    *TW* History:
    Me: 34 DH: 36 | Together since 2007 | Married July 2016

    TTC #1 since 7.2017
    Dx: low morph (1%), ANA positive, low decidualization score, high TSH and testosterone, histone antibodies

    IUI #1-3 all BFN
    IVF #1 | 6.11.19 | 24R, 17M, 15F, 6B, PGT-A tested - 5 normal, 3 girls & 2 boys
    FET #1 | 9.10.19 | BFN "I know you, but we've never met. I'm with you, but I don't know your name"
    RPL, Receptiva, & ERA testing | all normal/negative, recommended going on gluten and dairy free diet for next FET
    FET #2 | 3.31.20 | Opted to cancelled due to pandemic, continued diet and tried naturally over the summer
    2nd Opinion with another RE | 8.20.20 | Not immune to measles (received 1 dose); SA results similar to 2 years ago; decided to move forward with FET #2 redo at start of next cycle
    Surprise natural BFP! | 9.22.20 | MC 10.23.20 at 8 weeks
    TTCAL naturally | starting 11.22.20

    Initial consultation with Reproductive Immunologist | 9.14.21
    Decidualization score biopsy | 10.1.21 | abnormal - low score of 1; endometrial scratch recommended and progesterone supplementation
    Saline sono | 10.15.21 | normal
    Bloodwork | 10.21.21 high TSH, high testosterone, positive for anti-nuclear antibodies and histone antibodies, high protein S, multiple genetic mutations
    BFP! | 11.3.21 | EDD 7.14.22 B) | biopsy provided same effect as endometrial scratch; added supplemental progesterone and estrogen, prednisone, levothyroxine, and MTX Support to maintain pregnancy
    DS born 7.19.22 after induction


    TTC #2 begins 6.2023
    Consultation with RI | 6.6.23
    Saline sono, endometritis biopsy, skin & eye check | all normal
    Labs | high TSH, Factor XIII mutation, high %CD56
    Follow up | 8.8.23 | prescribed metformin, prednisone, plaquenil, and levothyroxine
    Repeat labs after 3 weeks on meds
    Follow up | 11.9.23 | Green light!, increase in prednisone, added lovenox
    Repeat labs in 8 weeks
    Follow up | 1.16.24 | Green light continues
    TTC put on pause
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    @pathomer, my clinic also only does FET after PGS.  Another thing, even if I had not done PGS this time and wanted to do a fresh transfer I would have been unable to because my progesterone was high and that can lower success rates.  That did not happen with my first cycle so you never know how your body is going to respond.
    Me: 35 DH: 40
    TTC #1 since 3/2017
    Dx: MFI
    DH varicocele repair 4/2018
    ER #1: 2/20/19; 7R/7M/7F/1D5B/1D6B (participated in a study so lower med protocol)
    2/25/19: ET #1 BFN
    4/24/19: FET #1 BFN
    ER #2: 6/9/19; 10R/8M/6F/3D5B/3D6B
    2 PGS 'NORMAL' GIRLS, 1 'indeterminate' GIRL
    7/30/19 FET #2 (Transfer #3): BFP??! EDD 4/16/20
    9/16/19 MMC
    9/18/19 D&C

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    @inthewoods23 I never thought about my body needing or even giving my body that opportunity to heal after the stim meds. -that’s a great point! Yes waiting really sucks.

    @mrsjones91716 yes the body is pretty fascinating- in terms of how it responds to meds and overall function. I have an appt tomorrow to see how my body responded to the BC, hopefully I get the ok to start the stim meds. Btw, this is like a second going to the clinic at least 2x a week. I’m so grateful I live close by the clinic and it’s not too far from my job. 
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    @ladyp0tter thanks and good luck to you too! Yes they offer rushed results for an additional fee (of course) only thing is if we end up with no quality embryos after the rushed results and we decide to do PGS again for a later IVF cycle we pay the cost all over again vs doing FET and paying one price to test up to 8 embryos across multiple cycles. We only pay for additional embryos beyond 8. 
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    @pathomer - we too have to pay for over 8. I got a call yesterday asking if we would want to since they are HOPING that I get at least 8 out of my 20 that fertilized. They said norm is 50% so that should be 10. I am praying for a couple extra just in case!!
    Me: 45yo, DH: 47yo
    3 Daughters (singleton @27yo, ID  Di/Di Twins @34yo)
    Protein S Deficiency (Blood Clotting Disorder), MTHFR & VIT D issue 
    5 MC's:  Blighted Ovum-D&C @ 9wks;  Natural MC @ 7wks; Blighted Ovum-D&C @ 9wks; MC boy-D&C @ 9wks & Chem PG in 2019
    Tubes were tied after my Twins (and now I am old). Remarried and want to give my DH a baby!

    IVF#1 OE June 2019 - ER 6/15/19, 24R, 21M, 20F, 7 6DBlasts Frozen for PGS Testing,
    RESULTS of PGS 4 abnormal girls,  2 abnormal boys, 1 indeterminate girl
    FET#1 OE August 23, 2019 (transferring 1 indeterminate girl & 1 abnormal boy) - BFN
    IVF#2 November 15, 2019 - ER 9R, 9M, 6F, 2 5dBlasts (fresh transfer) and 1 6DBlast frozen for PGS Testing,
    FRESH Transfer: November 20, 2019, 2 5-day blasts transferred!! 
    BFP 8dp5dt on 11/27 - 12/2 on FRER, BETA #1 12/2 - 11.93. BETA #2 12/4: 4.41 ~CHEMICAL PG
    ******************Starting Donor Process
    June 2020: Egg Donor Cycle and Fresh Transfer of 1 embryo in Czech Republic - CANCELLED DUE TO COVID19
    October 2020.  Split Cycle at UFC with a friend (Andrea) I met on the Bump who was also supposed to go to Prague too  
    DE Retrieval 9/26/2020, 26R, 24M, 12 split Cycle, 9 Fertilized + 1 "questionable", PRAYING FOR AT LEAST 5 BLASTS
    10/1/2020: 4 5DBlasts (AA, BB, BC, BC), 10/2/2020: 3 6DBlasts (BB, BB, BC) FOR A TOTAL OF: 7 BLASTS!! THANK YOU GOD!!
    PGS RESULTS: 5 NORMALS! DAY 5: AA BOY, BB GIRL, BC BOY / DAY 6: BB GIRL, BC GIRL
    DE FET October 29, 2020 - CANCELED DUE TO FLUID IN LINING
    DE FET November 16th, 2020 (transferring an PGS normal Hatching AA Boy)
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    @ladyp0tter wow that’s a healthy number! I’m praying for a couple of extra also...all the best!!! 
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     I prepped slightly different. I did 3 cycles in an effort to get enough blastocytes to PGS screen and will do my FET next month once I receive those results. My Dr. thinks that for certain patients, PGS screening at blastocyte stage/FET transfer at a later time gives the best outcome. I too am a little nervous about having to prep my body with more medication for the FET, however I've heard it's much less involved and not as stressful! Good luck! Wishing you the best!
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