Trouble TTC

Trigger Shots

Hi all,
 I know several of you have used trigger shots. My doctor wants me to add a trigger shot with the clomid to see if that will shorten my cycles and help us reach that elusive BFP. However she said this via online message and didn’t give me much info about them. Would love to know more if anyone is willing to share experiences. 


Re: Trigger Shots

  • I used trigger shots for every IUI cycle so far - they’re not bad at all! The benefit as I understand it is that the shot can help you release more than one follicle and also ensures it happens at a certain time so that you can schedule the IUI when it will be most effective. IMO it beats tracking and trying to figure things out naturally. 

    In in terms of experience they should give you instructions before you do it and there’s tutorials online too - but basically giving yourself a shot ends up not being bad at all. Some use their significant others. I’ve always done it myself and after I line up the shot I look away which helps. I did it on chlomid cycles and didn’t notice any specific side effects etc. You’ll do great 
  • I found the trigger a non-event also. The before hand anxiety of the unknown was way worse. I'm not good with needles. I still have to look away for blood draw but I was more than able to do the trigger myself. The needle is super fine and barely felt and I think it helps that you're pinching where it goes in (one time in you're life you will be elated if you're not "bikini ready" as I was hahaha). I didn't have any side effects either. You won't be able to do your own POAS though as I think it lingers in your system and can give false positive readings so you have to wait for the scheduled blood draw 14-16 days afterward. 
    Me: 36 DH: 37 // Married: 2015 // TTC#1 Since: 2017 // PAWrents to 2 dogs: 6 yo female shepherd-malamute & 1 yo male weim/heeler mix // Dx: Unexplained endometriosis & adenomyosis 12/2020 // Rx: 2019: IUIx6 & IVF Retrieval Result: Abnormal/High Mosaic Laparoscopy/Excision - Surgery Sep 2021, Round #2 IVF Retrieval with new clinic - 2022
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  • Thanks @optimism3 glad to hear they weren’t too bad. @hithertorue yeah that’s my big issue — I’m terrified of needles. Just the idea of it makes me feel sick. Glad to hear you didn’t find it too hard. LOL about body.. yep maybe I’ll finally be happy to have some
    of this extra fat.  Also dang re no POAS .... I wonder if my Dr will let me wait and see if AF shows up so I don’t have e to do a blood draw every time. Those are the worst! 

    Thank you both for the info!!
  • My trigger is injected in the back just above the butt so I always required DH's assistance. I could probably do it myself, but the needle is a bit long and I'm not sure how it would feel to do while I'm twisted to see my back.

    But yes, the needle may seem daunting, but it is thin (like 22 gauge or 25) and it just feels like a tiny pinch when it goes in
    *TW* History:
    Me: 34 DH: 36 | Together since 2007 | Married July 2016

    TTC #1 since 7.2017
    Dx: low morph (1%), ANA positive, low decidualization score, high TSH and testosterone, histone antibodies

    IUI #1-3 all BFN
    IVF #1 | 6.11.19 | 24R, 17M, 15F, 6B, PGT-A tested - 5 normal, 3 girls & 2 boys
    FET #1 | 9.10.19 | BFN "I know you, but we've never met. I'm with you, but I don't know your name"
    RPL, Receptiva, & ERA testing | all normal/negative, recommended going on gluten and dairy free diet for next FET
    FET #2 | 3.31.20 | Opted to cancelled due to pandemic, continued diet and tried naturally over the summer
    2nd Opinion with another RE | 8.20.20 | Not immune to measles (received 1 dose); SA results similar to 2 years ago; decided to move forward with FET #2 redo at start of next cycle
    Surprise natural BFP! | 9.22.20 | MC 10.23.20 at 8 weeks
    TTCAL naturally | starting 11.22.20

    Initial consultation with Reproductive Immunologist | 9.14.21
    Decidualization score biopsy | 10.1.21 | abnormal - low score of 1; endometrial scratch recommended and progesterone supplementation
    Saline sono | 10.15.21 | normal
    Bloodwork | 10.21.21 high TSH, high testosterone, positive for anti-nuclear antibodies and histone antibodies, high protein S, multiple genetic mutations
    BFP! | 11.3.21 | EDD 7.14.22 B) | biopsy provided same effect as endometrial scratch; added supplemental progesterone and estrogen, prednisone, levothyroxine, and MTX Support to maintain pregnancy
    DS born 7.19.22 after induction

    TTC #2 begins 6.2023
    Consultation with RI | 6.6.23
    Saline sono, endometritis biopsy, skin & eye check | all normal
    Labs | high TSH, Factor XIII mutation, high %CD56
    Follow up | 8.8.23 | prescribed metformin, prednisone, plaquenil, and levothyroxine
    Repeat labs after 3 weeks on meds
    Follow up | 11.9.23 | Green light!, increase in prednisone, added lovenox
    Repeat labs in 8 weeks
  • You’ll do great @2dogsmom. I hate needles too and used to get light-headed at the sight of them but this has made me
    acclimate. If you really can’t do it enlist your partner. If you do it, the key is to line it up, then not look when you inject as said. Listening to tv, music or a podcast helped me too. Its over before you know it 
  • Thanks @optimism3 ... I told my hubby he has to do it so we will see. I cried at the thought of having to do it because I hate needles so much but I also know I’ll get over it. 
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