Feel a little like an outsider here.
I am hoping for some advice
I am 26 years old. Have pcos and never have ovulated on my own. Started ttc at 22 years old. Went to a specialist and started iui
Second try was successfully (who knew how blessed we are) this was with 13 injections of menopur 50iu.
So fast forward to now. We have tried iui again 2 times. But my resistance to hormones is worse. (I need 24-30 injection to start making a folical)
I worry this means I have less eggs or poor quality?
My last cycle ending in a "chemical pregnancy" (hate the term because it feels like a loss to us)
This was with femzole 5mg for 5 days while taking, menopur 75iu and puregon 50iu. They also had to trigger. My poor tummy and emotions after this cycle.
The miscarriage left me with 2 large corpus luteum cyst so if these are gone when AF arrives on the 8th of Oct we will try IVF as the doctor has said IUI is not for us. Thankfully we can afford 1 try. But that's all.
So I came to this form looking for advice from someone who had the same/similar.
I am not sure why I need so many hormones now... I am also so afraid I don't get any eggies or they are all poor quality... But I know I would regret it more if we didn't try.
Feeling a bit hopeless at the moment
Re: Advice needed
Summer 2015 - no BFP yet, labs normal, referred to RE
Fall 2015 - Summer 2016 - Further testing all normal. 3 IUI's -- BFN. Recommended move to IVF. Planned cycle for fall 2016.
September 2016 - Surprise natural BFP. MMC @ 8 weeks. RE expressed confidence that we just needed the 'right' embryo.
Fall 2016 - Spring 2017 -- Break from TTC
June 2017 - Started IVF; egg retrieval for freeze all cycle. 9 mature eggs retrieved, 5 fertilized. 2 4BB embies on ice.
August 2017 - FET transfer both embies. BFP. Twin pregnancy confirmed by ultrasound. EDD 4/28/18
September 2017 - Twin B stopped developing; Twin A doing perfectly! Graduated from RE @ 10 weeks
March 2018 - Baby Girl born via C/S due to pre-eclampsia -- strong and healthy!
TTC #2
January/Feb 2021 - Freeze-all IVF cycle
March 2021 - FET of 1 PGS normal female embryo. BFP! Beta #1 156, #2 472, #3 1241, #4 5268 EDD 12/5/21 - Christmas baby!
"When all is lost then all is found."
Summer 2015 - no BFP yet, labs normal, referred to RE
Fall 2015 - Summer 2016 - Further testing all normal. 3 IUI's -- BFN. Recommended move to IVF. Planned cycle for fall 2016.
September 2016 - Surprise natural BFP. MMC @ 8 weeks. RE expressed confidence that we just needed the 'right' embryo.
Fall 2016 - Spring 2017 -- Break from TTC
June 2017 - Started IVF; egg retrieval for freeze all cycle. 9 mature eggs retrieved, 5 fertilized. 2 4BB embies on ice.
August 2017 - FET transfer both embies. BFP. Twin pregnancy confirmed by ultrasound. EDD 4/28/18
September 2017 - Twin B stopped developing; Twin A doing perfectly! Graduated from RE @ 10 weeks
March 2018 - Baby Girl born via C/S due to pre-eclampsia -- strong and healthy!
TTC #2
January/Feb 2021 - Freeze-all IVF cycle
March 2021 - FET of 1 PGS normal female embryo. BFP! Beta #1 156, #2 472, #3 1241, #4 5268 EDD 12/5/21 - Christmas baby!
"When all is lost then all is found."
Asked about the test and they said they do not do the test when they can see I don't have a low reserve.
I can't speculate why your dosage went up, other to say that for many of us this is what happens - the doc will keep upping dosages and adding more protocols until they get results. I took increasingly higher dosages of Puergon+trigger+TI for >5 cycles and never got any results before moving on to ivf.
One thing to try to keep you positive is to remember that IVF has a much higher success rate than IUIs. Yes, unfortunately there will be more shots and it is more invasive (I'm with you on hating the injections - I've never got used to them), but I really hope it will all be worth it for you. If you're going through IVF in October you should join in the Oct IVF thread - there'll be lots of ladies there going through the same thing and supporting each other.
Good luck
Married Oct 2010, TTC ~7yrs
Seeing RE since Spring 2013
Clomid - no response
Letrozole (6 months) 2015
Laperoscopy/Hysteroscopy in 2015
Puregon injectibles + trigger x5 in 2016 - all BFN
Started IVF March 2017 - 25 follies, 9 eggs, 3 fertilised, 1 survived-> frozen due to hyper stimulation of ovaries
FET May 16th 2017, BFP May 27th 2017, m/c @ 9wks
IVF #2 February 2018 - 16 eggs, 8 fertilised, 3 frozen embabies
Awaiting FET April 2018 - cancelled (cyst)
FET May 2018, BFP June 2nd 2018, m/c @ 8wks
FET October 2018 - BFN
Final FET - late November 2018