Hello all! I just wanted to introduce myself as you may see me posting from time to time. I'm an embryologist with several years experience in the clinic and about a decade background in molecular biology. I'm very happy to have found a career that allows me to help people directly (working in science can be pretty lonely) and I'm hoping to share my expertise with others who may need it. I'm also hoping to learn from all of you to better appreciate things from your point of view, which I'm sure will translate into making me a stronger embryologist (and person too!). I'll be cruising this board and others so if anyone has any embryology questions don't be shy to ask and I'll do my best to answer!!
I am Embryoman - your friendly neighborhood embryologist! **Removed for TOU violation**
Thanks! I’ll be getting results from a d&c soon and I’m going to an RE next month. I’ll let you know if I have any questions.
TTC#1 since Jan 2015 BFP 2/19/15 • MMC found at 9 wks • D&E at 11 wks (age 36) BFP 8/29/15 • CP (age 37)
BFP 11/18/15 • DD born at 41 weeks (age 37/38)
TTC#2 since May 2017 BFP 10/18/17 • MMC found at 8 wks • Misoprostal at 10.5 wks (age 39) BFP 2/16/18 • CP (age 39) BFP 4/13/18 • CP (age 39) BFP 5/07/18 • MMC found at 10.5 wks • D&E at 11.5 wks • Testing showed it was a girl with Trisomy 22. (age 39/40) 9/5/18 Diagnosed with diminished ovarian reserve (4-5 follicles, one ovary had none and was very atrophied) RE says the low egg count is likely causing my recurrent pregnancy loss. Less eggs results in more aneuploidy. BFP 9/24/18 • CP (age 40)
BFP 5/11/19 • Fraternal twins • MMC found at 10w5d (Baby A 6w, Baby B 10w) • Misoprostal at 11 weeks (age 41)
Welcome @embryoman. Fertility treatments (in my case, IVF with subsequent FETs) are a lonely, frustrating, mystical process that we only have *so* much info re: what's going on, so I'm sure your presence and insight will be highly valued on these boards!
**History in Spoiler**
Me-35, DH-36 - TTC since 08/10 Me - anovulatory, non-Insulin PCOS, DH - low end of "normal" sperm count IUI#1 - 02/15 - Cancelled due to scrubbed sperm count <1MM IVF#1 - 08/15 - 13x5-day blastocysts (ranging from AA-BB, most are 5 or 6), not PGS, on ice FET#1 - 10/15 - 1 emb - BFP (DD 07/16) (estrace + PIO sesame oil + prometrium) FET#2 - 07/17 - 1 emb - BFN (estrace + PIO sesame oil + prometrium) FET#3 - 08/17 - 1 emb - BFN (estrace + PIO sesame oil + prometrium) FET#4 - 10/17 - 2 emb - BFN (changed to estrace + prometrium because of allergic reaction to PIO sesame oil) ERA Testing - 12/17 - window moved (-1 day) FET#5 - 03/18 - 2 emb - BFN (estrace + prometrium, ERA-timing used) Karyotype Testing - 04/18 - Negative (we're ok) FET#6 - 06/18 - 2 emb - BFN (estrace + prometrium, ERA-timing used) FET#7 - 10/18 - 2 emb - BFN (estrace + prometrium, ERA-timing used) FET#8 - 11/18 - 2 emb - BFP; looks like one baby is going to make it, DD is due 8/16 (though likely to be 8/9)
I got the results from the d&c. It was a girl with Trisomy 22. Do you know if it’s likely that my first two missed miscarriages were chromosomal issues as well? And do you know if there are any treatments other than IVF with PGD? I’ll be seeing an RE on the 24th, but I was just curious.
TTC#1 since Jan 2015 BFP 2/19/15 • MMC found at 9 wks • D&E at 11 wks (age 36) BFP 8/29/15 • CP (age 37)
BFP 11/18/15 • DD born at 41 weeks (age 37/38)
TTC#2 since May 2017 BFP 10/18/17 • MMC found at 8 wks • Misoprostal at 10.5 wks (age 39) BFP 2/16/18 • CP (age 39) BFP 4/13/18 • CP (age 39) BFP 5/07/18 • MMC found at 10.5 wks • D&E at 11.5 wks • Testing showed it was a girl with Trisomy 22. (age 39/40) 9/5/18 Diagnosed with diminished ovarian reserve (4-5 follicles, one ovary had none and was very atrophied) RE says the low egg count is likely causing my recurrent pregnancy loss. Less eggs results in more aneuploidy. BFP 9/24/18 • CP (age 40)
BFP 5/11/19 • Fraternal twins • MMC found at 10w5d (Baby A 6w, Baby B 10w) • Misoprostal at 11 weeks (age 41)
@carrieandr I would suspect chromosomal issues that resulted in the miscarriages. From your history it sounds like PGS would be a good choice for your next IVF. That way you can transfer euploid embryos and have greater confidence. And if you were to miscarry then that is valuable information your RE could use for next steps.
I am Embryoman - your friendly neighborhood embryologist! **Removed for TOU violation**
TTC#1 since Jan 2015 BFP 2/19/15 • MMC found at 9 wks • D&E at 11 wks (age 36) BFP 8/29/15 • CP (age 37)
BFP 11/18/15 • DD born at 41 weeks (age 37/38)
TTC#2 since May 2017 BFP 10/18/17 • MMC found at 8 wks • Misoprostal at 10.5 wks (age 39) BFP 2/16/18 • CP (age 39) BFP 4/13/18 • CP (age 39) BFP 5/07/18 • MMC found at 10.5 wks • D&E at 11.5 wks • Testing showed it was a girl with Trisomy 22. (age 39/40) 9/5/18 Diagnosed with diminished ovarian reserve (4-5 follicles, one ovary had none and was very atrophied) RE says the low egg count is likely causing my recurrent pregnancy loss. Less eggs results in more aneuploidy. BFP 9/24/18 • CP (age 40)
BFP 5/11/19 • Fraternal twins • MMC found at 10w5d (Baby A 6w, Baby B 10w) • Misoprostal at 11 weeks (age 41)
Re: Introducing myself
BFP 2/19/15 • MMC found at 9 wks • D&E at 11 wks (age 36)
BFP 8/29/15 • CP (age 37)
TTC#2 since May 2017
BFP 10/18/17 • MMC found at 8 wks • Misoprostal at 10.5 wks (age 39)
BFP 2/16/18 • CP (age 39)
BFP 4/13/18 • CP (age 39)
BFP 5/07/18 • MMC found at 10.5 wks • D&E at 11.5 wks • Testing showed it was a girl with Trisomy 22. (age 39/40)
9/5/18 Diagnosed with diminished ovarian reserve (4-5 follicles, one ovary had none and was very atrophied)
RE says the low egg count is likely causing my recurrent pregnancy loss. Less eggs results in more aneuploidy.
BFP 9/24/18 • CP (age 40)
Me - anovulatory, non-Insulin PCOS, DH - low end of "normal" sperm count
IUI#1 - 02/15 - Cancelled due to scrubbed sperm count <1MM
IVF#1 - 08/15 - 13x5-day blastocysts (ranging from AA-BB, most are 5 or 6), not PGS, on ice
FET#1 - 10/15 - 1 emb - BFP (DD 07/16) (estrace + PIO sesame oil + prometrium)
FET#2 - 07/17 - 1 emb - BFN (estrace + PIO sesame oil + prometrium)
FET#3 - 08/17 - 1 emb - BFN (estrace + PIO sesame oil + prometrium)
FET#4 - 10/17 - 2 emb - BFN (changed to estrace + prometrium because of allergic reaction to PIO sesame oil)
ERA Testing - 12/17 - window moved (-1 day)
FET#5 - 03/18 - 2 emb - BFN (estrace + prometrium, ERA-timing used)
Karyotype Testing - 04/18 - Negative (we're ok)
FET#6 - 06/18 - 2 emb - BFN (estrace + prometrium, ERA-timing used)
FET#7 - 10/18 - 2 emb - BFN (estrace + prometrium, ERA-timing used)
FET#8 - 11/18 - 2 emb - BFP; looks like one baby is going to make it, DD is due 8/16 (though likely to be 8/9)
BFP 2/19/15 • MMC found at 9 wks • D&E at 11 wks (age 36)
BFP 8/29/15 • CP (age 37)
TTC#2 since May 2017
BFP 10/18/17 • MMC found at 8 wks • Misoprostal at 10.5 wks (age 39)
BFP 2/16/18 • CP (age 39)
BFP 4/13/18 • CP (age 39)
BFP 5/07/18 • MMC found at 10.5 wks • D&E at 11.5 wks • Testing showed it was a girl with Trisomy 22. (age 39/40)
9/5/18 Diagnosed with diminished ovarian reserve (4-5 follicles, one ovary had none and was very atrophied)
RE says the low egg count is likely causing my recurrent pregnancy loss. Less eggs results in more aneuploidy.
BFP 9/24/18 • CP (age 40)
**Removed for TOU violation**
BFP 2/19/15 • MMC found at 9 wks • D&E at 11 wks (age 36)
BFP 8/29/15 • CP (age 37)
TTC#2 since May 2017
BFP 10/18/17 • MMC found at 8 wks • Misoprostal at 10.5 wks (age 39)
BFP 2/16/18 • CP (age 39)
BFP 4/13/18 • CP (age 39)
BFP 5/07/18 • MMC found at 10.5 wks • D&E at 11.5 wks • Testing showed it was a girl with Trisomy 22. (age 39/40)
9/5/18 Diagnosed with diminished ovarian reserve (4-5 follicles, one ovary had none and was very atrophied)
RE says the low egg count is likely causing my recurrent pregnancy loss. Less eggs results in more aneuploidy.
BFP 9/24/18 • CP (age 40)