Hi everyone. At our WTF appointment at the end of November, my RE decided to start me on Metformin because my AMH levels (back in JANUARY) indicated I might have PCOS. Mind you, my level was 5.91 (I was 37 at the time, just turned 38) and anything over 5 is considered a "diagnostic criterion for PCOS" but usually in conjunction with other tests.
Despite all the many tests and ultrasounds I have had in the past year, including when I wasn't on any hormones, no one ever told me I had reason to worry about PCOS. They did not mention multitudes of cysts. I didn't hyperstimulate during my retrieval cycle. When not on meds, I seem to ovulate at the same time every month (via LH test strips and CM observation) and my periods are the same length each month. Other than being overweight (which is due primarily to being mostly sedentary and working in an office, not to mention my affinity for food that's horrible for me) I don't have any of the classic symptoms of PCOS (hirsutism, acne, hair loss).
So I went on Metformin ER - 500 mg. once per day for a week, then moved up to 1000 mg. (always taking them with food) and I have been SO SICK. Anything I eat comes right out of me (sorry TMI) and I am constantly hungry because my intestines are clearly unable to derive actual nutrients from my food before violently expelling it.
My question is: Is Metformin really going to make or break my FETs going forward, does anyone know? I have 9 embryos on ice and I'm not planning on doing another retrieval in the near future and hopefully not ever again. I would almost rather end up childless than feel nauseated and have diarrhea every day all day, which for me is saying a lot, but it's complete torture.