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Crinone

LoveDontCostAThingLoveDontCostAThing member
in Infertility
Hey.  I've been taking crinone 2x a day for almost two weeks.  Not much has "leaked out" until yesterday and today.  I am 7dp5dt.  SO SORRY for TMI, but yesterday it came out when I peed like cottage cheese looking, and it happened again today.  Of course I have googled, so I know that can be normal, but it is still kind of alarming since it didn't happen prior to this.  I have tried "cleaning myself out" a few times in the shower, but no clumps came out.  Do you think it's just over build up?  Or is my body not absorbing it?  Now I'm going OCD that the transfer didn't work and my body is rejecting it.  
Me: 33, DH: 40
July 2016: IVF #1 (froze embryos)
Aug. 2016: Hysteroscopy to remove a few polyps & Laparoscopy
Oct. 2016: FET #1 BFN
Nov. 2016: FET #2 BFP (ended in CP)
March 2017: IVF #2 Fresh Transfer of 2 Blasts = BFP!!! (EDD: 11/27/17)
Froze 5 Blasts
DS born on 11/2/17!!!  
Back to try for Baby #2 :)


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Re: Crinone

  • ChocolateIsLifeChocolateIsLife member
    *TW signature* and lurking

    Hey girl! I take Crinone 2x daily and thought the same thing. Thick chunky globs kept randomly coming out, even though I thought I had cleaned it out. It is completely normal though. Your body absorbs the suppository within the first 20-40 minutes, so anything left is just the carrier ingredients of the suppository, and not needed. I have to wear a panty liner, otherwise its a nasty mess. I just wanted to share, because I thought the same thing was happening but it is all normal. 
    Me: 31 DH:35
    TTC #1: March 2011 
    Fur-children: 3 dogs + 2 cats (all rescued)
    dx: Endometriosis and Fibroids 
    2 Laps and 1 Abdominal Myomectomy
    6 rounds of clomid
    5 rounds of iui
    IVF #1 Gonal F, Menopur and Cetrotide
    ER 12/1/2016:Retrieved 22 eggs 12 fertilized, developed moderate OHSS
    4/4 day 5 embryos were normal for PGS!!! 2 boys/2 girls
    FET 1/10/2017  
    Gallbladder surgery 1/10/2017
    FET 2/2
    BFP 2/7/17 <3 Beta#1: 594!!! Beta#2 1630!!!
    Having a girl! EDD 10/21/17
    Pregnancy Ticker
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  • LoveDontCostAThingLoveDontCostAThing member
    @ChocolateIsLife -hey, thank you!  why do you think it suddenly started to come out?  It didn't for the first week or so.  congrats on your pregnancy! 
    Me: 33, DH: 40
    July 2016: IVF #1 (froze embryos)
    Aug. 2016: Hysteroscopy to remove a few polyps & Laparoscopy
    Oct. 2016: FET #1 BFN
    Nov. 2016: FET #2 BFP (ended in CP)
    March 2017: IVF #2 Fresh Transfer of 2 Blasts = BFP!!! (EDD: 11/27/17)
    Froze 5 Blasts
    DS born on 11/2/17!!!  
    Back to try for Baby #2 :)


    Report Reply
  • ChocolateIsLifeChocolateIsLife member
    @LoveDontCostAThing Thank you!!!! <3 

    I always have a delay in the discharge coming out. It's like it takes a while to get to that thick consistency. I try and get as much of it out as I can every few days (thats what the nurse said to do), but it gets really tender and I get nervous about scraping around up there. Also, It can hide in the crevices of the canal until it builds up enough to come out. It is also normal for it to be different colors, and it changes to pink for some people. I actually had dark gray/black streaks in mine a few weeks ago and had a meltdown thinking something was happening, but it is all normal. They should really give us a heads up about these things!
    Me: 31 DH:35
    TTC #1: March 2011 
    Fur-children: 3 dogs + 2 cats (all rescued)
    dx: Endometriosis and Fibroids 
    2 Laps and 1 Abdominal Myomectomy
    6 rounds of clomid
    5 rounds of iui
    IVF #1 Gonal F, Menopur and Cetrotide
    ER 12/1/2016:Retrieved 22 eggs 12 fertilized, developed moderate OHSS
    4/4 day 5 embryos were normal for PGS!!! 2 boys/2 girls
    FET 1/10/2017  
    Gallbladder surgery 1/10/2017
    FET 2/2
    BFP 2/7/17 <3 Beta#1: 594!!! Beta#2 1630!!!
    Having a girl! EDD 10/21/17
    Pregnancy Ticker
    Report Reply
  • LoveDontCostAThingLoveDontCostAThing member
    @ChocolateIsLife -thank you...you eased my worry!  I put a call/ voicemail in to the ivf nurses too just in case.  I also get nervous scraping around up there too much.  In the shower I don't get much out, which is odd.  So I think you're right that is was probably hiding in the crevices and finally came out...ew, so gross to think about!!  The things we have to do!!
    Me: 33, DH: 40
    July 2016: IVF #1 (froze embryos)
    Aug. 2016: Hysteroscopy to remove a few polyps & Laparoscopy
    Oct. 2016: FET #1 BFN
    Nov. 2016: FET #2 BFP (ended in CP)
    March 2017: IVF #2 Fresh Transfer of 2 Blasts = BFP!!! (EDD: 11/27/17)
    Froze 5 Blasts
    DS born on 11/2/17!!!  
    Back to try for Baby #2 :)


    Report Reply
  • JamieH2000JamieH2000 member
    @lovedontcostathing- I had the same experience with crinone too! It also made me crampy and the wetness made me think AF was always coming! Overall I preferred it to PIO, but it still messed with my mind a lot!
    History in Spoiler

    Age: 32 (same with DH). Together since 2006, Married June 2013 and TTC since August 2015
    Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive)
    March-May 2016: 1 TI and 2 IUIs- BFN 
    June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary.
    August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN
    Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN
    January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze :(), BFN
    May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline :(
    Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid :(
    Nov 2017- Hysterscopy to remove polyp
    Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated
    Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone
    Apr 2018- DE FET cancelled for lining issues :(
    Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin
    Baby Born born early @ 33.5 weeks due to Pre-e
    Back for # 2!
    Report Reply
  • LoveDontCostAThingLoveDontCostAThing member
    @JamieH2000- ugh I've tried all the progesterone methods!  I hate the PIO the most...never again.  I've been crampy the entire time since transfer, so I can't tell what is caused by what.  Although, before transfer I had to take it for a few days, and I don't remember being crampy then.
    Me: 33, DH: 40
    July 2016: IVF #1 (froze embryos)
    Aug. 2016: Hysteroscopy to remove a few polyps & Laparoscopy
    Oct. 2016: FET #1 BFN
    Nov. 2016: FET #2 BFP (ended in CP)
    March 2017: IVF #2 Fresh Transfer of 2 Blasts = BFP!!! (EDD: 11/27/17)
    Froze 5 Blasts
    DS born on 11/2/17!!!  
    Back to try for Baby #2 :)


    Report Reply
  • katherindkatherind member
    My nursing team also said that some strange things can occur with the discharge, and most of what you described is normal. They also suggested gently cleaning out daily to avoid any irritation. The progesterone absorbs very quickly, and the rest is just the oily residue left over. I just started Crinone this morning, so it's too early for me to deal with the discharge. I'm glad you all posted about it though so I know what I could expect in the coming weeks.

    *km*
    me 29  |  him 32  |  married: 4/27/2013

    TTC#1 (2/14/2017 - 4/7/17):
    Menopur = 19.66mm (R) & 17.02mm (L)| Ovidrel: 3/14/2017 | TIC 3/14-3/17/17 | *TWW* | Beta #1 3/30: 7.27 | Beta #2 4/3: 11.94| Beta #3 4/5: 8.02 | Beta #4 4/7: 2.24 | Ended as chemical pregnancy.

    TTC#2: (4/10/2017 - 5/12/17):
    Menopur = 13.59mm (R) & 21.68mm (L)| Ovidrel: 4/27/17 | TIC 4/27-4/30/17 | *TWW* | Beta #1: 0.1 = BFN

    TTC#3: (5/16-present)
    Menopur = 17mm + 13.5mm (L) 19.5mm (R) | CD11 Ovidrel 5/26/17 | TIC 5/26-5/28/17 | *TWW* | Beta #1 6/12: 9.91 | Beta #2 6/14: 13.89 | Beta #3 6/16: 20.81 | Beta #4 6/19: 41.46 | Beta #5 6/21: 24.50 | Beta #6 6/30: TBD - Will test until numbers reach zero.
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  • LoveDontCostAThingLoveDontCostAThing member
    @katherind -I ended up talking to one of the IVF nurses at my doctors yesterday, and she said that the discharge is normal.  I think it must have built up over the past couple of weeks because there was no discharge in the beginning.  It's definitely good to be warned!  I try cleaning it out, but barely any comes out.  Instead, it has been falling out when I pee here and there...ohh well, at least it's in the toilet.  So lovely!
    Me: 33, DH: 40
    July 2016: IVF #1 (froze embryos)
    Aug. 2016: Hysteroscopy to remove a few polyps & Laparoscopy
    Oct. 2016: FET #1 BFN
    Nov. 2016: FET #2 BFP (ended in CP)
    March 2017: IVF #2 Fresh Transfer of 2 Blasts = BFP!!! (EDD: 11/27/17)
    Froze 5 Blasts
    DS born on 11/2/17!!!  
    Back to try for Baby #2 :)


    Report Reply
  • DungeonTrollMelDungeonTrollMel member
    I'm not on crinone but I am on a progesterone cream and estrogen cream vaginally. It's constant white chunkiness. Panty liners and baby wipes are your best friend 
    BFP #1: 1.22.16                 MMC: 2.29.16 ( tetrasomy 11, partial deletion 1, XXX) D&C: 3.2.16
    BFP #2: 4.14.16                 CP: 4.17.16
    BFP #3: 6.10.2016             CP: 6.17.16
    RE appt: 6.27.2016- saline sono all clear
    Progenity: + carrier Tay-Sachs, Gaucher's, hemachromatosis. DH: carrier Alpha 1 anti-trypsin
    PCOS, hypothyroid, MTHFR, hx of LEEP in 2006
    Clomid + TI Cycle #1: 50mg Trigger 8.24.2016- BFN
    Clomid 75mg + IUI#1 9.25.2016- BFP #4 10/6
    Beta #1 15   Beta #2 38    Beta #3- 71     beta #4 171   Beta # 5- 21  Natural MC 10/21
    HSG- clear
    IVF Jan 2017
    Egg Retrieval 1.22.17: 32 eggs retrieved,29 mature, 24 fertilized, 14 to blastocyst for biopsy
    PGS results: 4 PGS normal 2 XX, 2 XY
    FET: 3.13.2017 for 2 PGS embryos
    Beta#1: 3.24.2017......... 78; Beta # 2 241; Beta #3 4198
    Baby BOY due 11.29.2017






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  • katherindkatherind member
    @lovedontcostathing I'm experiencing the same thing. It's only been a few days, but mine is also coming out the same way. In the shower, I get hardly anything. During the day though, it just sort of comes out on its own. Thank goodness for liners! lol.

    *km*
    me 29  |  him 32  |  married: 4/27/2013

    TTC#1 (2/14/2017 - 4/7/17):
    Menopur = 19.66mm (R) & 17.02mm (L)| Ovidrel: 3/14/2017 | TIC 3/14-3/17/17 | *TWW* | Beta #1 3/30: 7.27 | Beta #2 4/3: 11.94| Beta #3 4/5: 8.02 | Beta #4 4/7: 2.24 | Ended as chemical pregnancy.

    TTC#2: (4/10/2017 - 5/12/17):
    Menopur = 13.59mm (R) & 21.68mm (L)| Ovidrel: 4/27/17 | TIC 4/27-4/30/17 | *TWW* | Beta #1: 0.1 = BFN

    TTC#3: (5/16-present)
    Menopur = 17mm + 13.5mm (L) 19.5mm (R) | CD11 Ovidrel 5/26/17 | TIC 5/26-5/28/17 | *TWW* | Beta #1 6/12: 9.91 | Beta #2 6/14: 13.89 | Beta #3 6/16: 20.81 | Beta #4 6/19: 41.46 | Beta #5 6/21: 24.50 | Beta #6 6/30: TBD - Will test until numbers reach zero.
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