Infertility

EFT TEST Yale - Please Respond

A little about our story.

I am 33 and my husband is 41. We were trying naturally for over a year when, in November 2015, we decided to go to a fertility doctor. At first, my husband was diagnosed with acute varicocele. It is so severe that if he undergoes an operation to rectify it, it may result in him becoming completely sterile. My husband’s sperm count was as follows:

Volume: 5.8 mL                                       ( > 1.5mL)

Concentration: 0.7 million/mL          ( > 20 million/mL)

Motility 33 % motile                              ( > 50% motility)

Morphology (shape)  1 % normal    ( > 4% normal by strict criteria)

We proceeded to begin our IVF cycle in December, and completed our transfer on 01/23/16. This unfortunately was unsuccessful. From retrieving 28 eggs (and feeling immensely over stimulated), we transferred two, and were left with one blast of poor quality.

With finding out that this had failed, we decided to consult with another doctor. She carried out the same tests and concluded that I appeared to be normal, and my husband should begin taking a small dose of clomid to help with his infertility and prepare for another cycle. We had to have the remaining blast transferred between doctors’ offices as my insurance would not approve another cycle of IVF without using all available blasts. Upon receiving the embryo, my new doctor said that it should never have been frozen, and didn't expect for it to work. We transferred in April.

We were able to begin another fresh IVF cycle in June. I found the experience to be less harsh than my first, and the quality of the blasts were much higher than we had had previously. We transferred two in June, and were very optimistic that they would take. I ate pineapple, I rested and took some time off from work. Unfortunately, it did not work again.

At this point, having three failed transfers, my doctor decided to do more tests on me, and found that I had elevated natural killer cells. For my fourth transfer, she put me on an intralipid transfusion about a week before hand. We transferred two in September, again they did not take. 

Puzzled at this point, my doctor recommended I undergo a mock cycle, and take the Endometrial Function Test (EFT) through Yale. My doctor seems to think that I may have an infection in my uterus, causing the embryo's not to take. I had the Bioposy for the test taken yesterday, and am now to wait about two weeks for results. 

I am sick to my stomach to think that we might be told that all hope is lost. I can’t think about anything else right now. I am so anxious.

I can find very little online from other couples that have gone through the EFT, and wondered if I could find anyone here that can share their story, or experience.

I am currently a patient at the Sher Institute, NYC. Looking forward to hearing from someone, anyone!

Re: EFT TEST Yale - Please Respond

  • I have not gone through the EFT, but I wanted to at least reach out to you. It sounds like you have been on quite a frustrating journey thus far. I know it's so, so difficult each time you receive a new possible diagnosis, as the unknown can be so scary. (We are still waiting to be able to get the tests done for more information in our situation.) I know that two weeks can seem like it takes forever, but this awesome community will be here during that time. I've found that trying to stay busy with my running club and friends has helped me to be less anxious during the tense waiting period. I hope your test will reveal good news, or at least shed more light on your situation. <3
    Me: 35 DH: 28
    TTC since June 2016

    Azoospermia diagnosis (zero count) Dec 2016

    AZFc chromosome microdeletion discovery March 2017
    Unsuccessful TESE for DH in August 2017
    October 2017 IVF with donor sperm
    29R, 24M, 16F, 2d5, 4d6 (6 embryos total)
    Only 3 could have PGS. 2/3 normal. 5 embies frozen
    12/15/17 FET #1 (1 embryo)--CP
    2/7/17 FET #2 (2 embryos)--BFN
    Chronic endometritis diagnosis May 2018
    ERA Sept 2018--borderline receptive--12 more hours of progesterone
    Abnormal SIS Oct 2018
    Repeat hysteroscopy Nov 1. Treated recurring endometritis.
    12/4/18 FET #3 (2 embryos)--BFN
    Our journey has come to an end.
    ~*~*~Nevertheless, she persisted~*~*~
  • Loading the player...
  • I haven't undergone EFT but welcome to our community! And GL!
    Siggy Warning--------


    CP #1- due April 2017 lost 5.5 weeks
    cp #2- due May 2017 lost at 4.5 weeks
    iUI #1- BFN
    IUI #2-BFN
    IVF#1- transfer 2- BFP! Due October 2017 c/p#3 lost at 3.5 weeks
  • I have not had EFT, but I did have ERA- endometrial receptivity array which  looks at whether or not your uterine line is receptive on the day they think it is. I went through 2 of those biopsies and got a pretty confusing result, but it still gave us more answers- and after repeated implantation failure I am glad I did.
    ***TW***
    DH & I both 34.
    8/16: IVF, antagonist protocol 
    21 eggs | 9 blasts | 7 normal through PGS
    10/16: FET  = BFN  :(
    12/16: Surprise natural BFP 
    Beta 1: 177 | Beta 2: 483 | Beta 3: 8,755 | Beta 4: 39,007. Baby born 9/5/2017

    NOW on sibling journey. 
    2/20: FET = BFN :(
    4/20: Surprise COVID BFP

  • Thanks for responding everyone, I'm feeling so very alone, it would be nice if there was more information available online etc. I do appreciate your response :)
  • @AnnAnselmo - I haven't been through this, but just wanted to say I am sorry for your struggles. Sounds like you have had a really tough couple of years!

    When you said: "I am sick to my stomach to think that all hope is lost. I can't think about anything else right now. I am so anxious." my heart went out to you. IF is the worst! 4 failed transfers? So painful!

    Do you have many blasts left?  FX for you and good luck in the future! I hope you get more information -at the very least - soon.
  • I have 3 blasts left. I'm comforting myself this morning with the fact that, this time last year, we were going through our first IVF cycle, and the blasts quality was so poor. We changed doctors after that, and she was able to improve the quality to near perfect. This is just another hurdle we have to jump over, and we will :) Positive thoughts!!!!!
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