CP #1- due April 2017 lost 5.5 weeks cp #2- due May 2017 lost at 4.5 weeks iUI #1- BFN IUI #2-BFN IVF#1- transfer 2- BFP! Due October 2017 c/p#3 lost at 3.5 weeks
@LoveDontCostAThing thats my question, normally the answer is yes, you do an FET cuse they are frozen. Does your body have to prepare differently between fresh transfer and frozen. Since I have low amh my body shouldn't experience any OHSS during the next ivf cycle, so I'm wondering, if I take one from round 1 - (praying I have at least have a normal one)...couldn't I take that one and do a transfer during the following cycle of ivf. The eggs i get in cycle 2 will go to get tested, and then instead of doing a 3 of 5 day transfer with those eggs i can thaw one from the cycle before...this current cycle. The thought I've first getting to any type of transfer is like 3 months away then...which really doesn't make me happy.
History of TTC in spoiler box
TTC since 2014 Unexplained Infertility - but I am 40...Low AMH .30 7 - IUI (50mg-150mg Clomid) Feb - August 2016 all BFN IVF#1 August 2016 (Antagonist protocol 4/5 eggs) Cancelled cycle RE thought I would get at least 10. IVF#2 Sept 2016 (microdose luporn pro - disappearing follies, ONLY ONE, convert to IUI) BFN IVF#3 November 2016 (4 ER, 3 F, 3DT)-BFP with TWINS // MC both at almost 10wks IVF#4 March 2017 //EPP (10 ER (1 wonky so 9 ER) 7F, 3B (5AB, (2)5BB) PGS tested- ALL abnormal IVF#5 April 2017 // EPP (7 ER, 7F yes! 6B) 2/5 day 4/6 day - 2 PGS normal! yes!! IVF#6 May 2017 // Antagonist didn't have time for Estrogen Priming...(4 ER, 3 F, 3B) (5AB, (2) 5BB) 2 PGS normal, yes!! IVF#7 June 2017 // EPP praying this is it and then on to an FET!
@Hopeful_mom I wanted to start prepping the cycle after retrieval but the nurse didn't think we'd get the results back in time (we did). However, the FET was going to be around Christmas, so we were pushed into January.
Me:32 DH:36 Me: DOR, poor egg quality, MTHFR DH: MFI TTC since 3/2014 2015: 3 IUI's-BFN 12/2015: 1st IVF cycle-(9 follicles retrieved, 5 mature, 3 fertilized w/ICSI, transferred 1 excellent and 1 good embryo on day 3)-chemical pregnancy 3/2016: 2nd IVF cycle- canceled (3 follicles retrieved, 3 mature, all fertilized w/ICSI, 1 fragmented, 2 arrested) 3/2016: RE suggested donor eggs- taking an ivf break and to supplement 9/2016: 3rd ivf cycle-cancelled due to early ovulation Oct./Nov 2016: 4th ivf cycle- EPP-AFC:5, retrieved 10, 10 mature, 8 fertilized with ICSI, 6 blastocysts biopsied and frozen. 3 CCS normal embryos
1/9/17: transferred 1 embryo-BFP 1/16 1/18/17: beta #1-104 1/20/17: beta #2-174 2/2/17: first u/s, heartbeat of 107 at 6w1d 7/20/17: baby boy born at 30+3 via emergency c-section
@Hopeful_mom all I can speak to is my experience and with a frozen they had me prep with estrace at the beginning of the cycle and added in PIO around day 15 or so.... So I have no idea if using frozen right after ER would work! It's an interesting question. I could try that too but I know my clinic would never go for it
Siggy Warning--------
CP #1- due April 2017 lost 5.5 weeks cp #2- due May 2017 lost at 4.5 weeks iUI #1- BFN IUI #2-BFN IVF#1- transfer 2- BFP! Due October 2017 c/p#3 lost at 3.5 weeks
thanks for the info! I'm sure my clinic wont go for it, but you know i'm going to ask
History of TTC in spoiler box
TTC since 2014 Unexplained Infertility - but I am 40...Low AMH .30 7 - IUI (50mg-150mg Clomid) Feb - August 2016 all BFN IVF#1 August 2016 (Antagonist protocol 4/5 eggs) Cancelled cycle RE thought I would get at least 10. IVF#2 Sept 2016 (microdose luporn pro - disappearing follies, ONLY ONE, convert to IUI) BFN IVF#3 November 2016 (4 ER, 3 F, 3DT)-BFP with TWINS // MC both at almost 10wks IVF#4 March 2017 //EPP (10 ER (1 wonky so 9 ER) 7F, 3B (5AB, (2)5BB) PGS tested- ALL abnormal IVF#5 April 2017 // EPP (7 ER, 7F yes! 6B) 2/5 day 4/6 day - 2 PGS normal! yes!! IVF#6 May 2017 // Antagonist didn't have time for Estrogen Priming...(4 ER, 3 F, 3B) (5AB, (2) 5BB) 2 PGS normal, yes!! IVF#7 June 2017 // EPP praying this is it and then on to an FET!
I'm so glad I've found this thread. Though I'm extremely sad that we're all having so much difficulties conceiving.
I've now had 2 IVF cycles and oh boy, I never thought that I will end up with no normal embryos. I've had 6 IUI cycles prior to the IVF cycles and when all 6 IUIs ended with BFNs, I thought, hey, there's always IVF. Surely IVF will work, because the success rate is so high!
Well... that wasn't the case. Not for me anyways. My problem seems to be that the majority of eggs are immature. I've now had two luteal stimulation protocols and both cycles produced low % of mature eggs. The first cycle was a little less than 50%, the second cycle was only 30% mature. After two consecutive failures, my RE acknowledged that the luteal stimulation protocol doesn't work for me. So for the upcoming cycle, we are trying the traditional IVF protocol, the long agonist protocol. Hoping that will yield higher % of mature eggs, and also normal embryos. Like some of you, I'm also banking embryos as DH and I want two kids, if possible.
Me: 41 DH: 46 Unexplained infertility/AMA, polycystic ovaries, insulin resistance FET#1(July 2017): eSET of first of 4 PGS-normal embryos, DS born 3/30/2018 FET#2(Oct/Nov 2019): eSET
cashewchicken - I am glad your RE is changing the protocol. That can make all the difference. My first IVF was cancelled for poor response and the second I only got 2 eggs. My third I did Estrogen priming with antagonist and I got 12 eggs (8 mature)! Hopefully the new protocol will be all you need! Keep us posted!
@gwinnyblack- good luck! I am hoping to start round 4 soon too. Hoping for lots of eggs for yoU!
History in Spoiler
Age: 32 (same with DH). Together since 2006, Married June 2013 and TTC since August 2015 Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive) March-May 2016: 1 TI and 2 IUIs- BFN June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary. August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze ), BFN May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid Nov 2017- Hysterscopy to remove polyp Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone Apr 2018- DE FET cancelled for lining issues Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin Baby Born born early @ 33.5 weeks due to Pre-e Back for # 2!
Well I'm on to number four. We met with the doctor today and will start with my May period so we can take some time but we are doing half of my eggs with my husbands sperm and half with a donor sperm. I'm hoping for a miracle so we can have an embryo make it to day five with my husbands sperm but at least the donor sperm will be there to back him up. I'm not sure if I'm ready for it. Are any of you in the same situation with donor sperm or egg? How did you get past it? He is ok with it and doesn't understand how I am not but we are having the discussions and starting again in May. Good luck to all of you. I'm really sorry you are in this category.
@Msymmers922 We've considered donor eggs...I go back and forth about it. At the end of the day though, the money is our barrier to donor eggs. I think the minute I saw that little heartbeat on the ultrasound screen, that I wouldn't care about whose DNA it actually was. I hope that things work out for you and that number four is your cycle.
TTC since August 2014
Me: 41, Him: 43
DX: Unexplained secondary infertility
History: Multiple months of Clomid/Femara End of March 2015: BFP with Femara! Saw heartbeat at 5.5 weeks. M/C at 11 weeks Multiple more months of Femara IUI #1 with Femara and Follistem 75 units: BFN IUI #2 with Follistem 150 units: BFN Dec 2015: 1st IVF. 10 eggs retrieved with 8 eggs fertilized. 5 day transfer of two embryos with 2 frozen embies. BFN January 2016: FET #1 2 embryos: BFN March 2016: 2nd IVF cycle. 4 eggs retrieved with 2 fertilized. Quick two day transfer of both embryos: BFN April/May 2016 IVF #3. 11 eggs retrieved. 10 mature. 7 fertilized. 2 5AA blasts transferred 5/11/2016 BFN September 2016 IVF #4: 17 follicles growing, premature ovulation through Cetrotide. Retrieval cancelled. April 2017 IVF #5: 9 follicles growing, 6 eggs retrieved with 5 fertilized. Transfer of three blasts. BFN June 2017: IVF #6: 2 follicles growing, 5 eggs retrieved with 5 fertilized. Transfer of 5 3-day embryos. Chemical pregnancy. BFN Nov/Dec 2017: Donor egg cycle. 33 eggs retrieved, 26 mature. 26 fertilized.
@JamieH2000: I'm hoping the new protocol makes a huge difference. If it doesn't, then at least we will know the cause of my infertility... I was hoping to change the protocol for the second cycle, but the doctor thought it would be best to repeat it... At least this is something to look forward to. Hoping your #4 is it!
@Msymmers922: I am still trying with my own eggs, but I am open to donor eggs as well, if egg quality turns out to be an issue we can't overcome. A close friend of mine recently tried IVF with donor eggs and she's in early stages of her pregnancy. For her, she was diagnosed with diminished ovarian reserve, and the chance of her having children with her own eggs was slim to none. Since she and her husband both wanted kids, the choice was either adopting or using donor eggs. Her husband was initially hesitant (like you), but she really wanted to, as the baby will be at least genetically linked to her husband, and she will carry and deliver the child. I think the difficulty of the adoption process also made them try the donor egg route first.
Me: 41 DH: 46 Unexplained infertility/AMA, polycystic ovaries, insulin resistance FET#1(July 2017): eSET of first of 4 PGS-normal embryos, DS born 3/30/2018 FET#2(Oct/Nov 2019): eSET
@Msymmers922 I am open to donor eggs. My clinic wants me to work my way through my 4 ERs first though. I'm halfway through them so far.
Siggy Warning--------
CP #1- due April 2017 lost 5.5 weeks cp #2- due May 2017 lost at 4.5 weeks iUI #1- BFN IUI #2-BFN IVF#1- transfer 2- BFP! Due October 2017 c/p#3 lost at 3.5 weeks
@gwinnyblack: Did you do a Fresh transfer or FET? Do you have any frosties? Best of luck on your tww, when is your beta?
cashewchicken sorry ur having such a hard time and find yourself here, its not easy indeed! Like @jamieh2000 mentioned the right protocol can be all you need. I did 6 IUIs as well, I even double down on some IUI cycle with some great samples and still bfn (TW) On my third cycle of IVF and did manage to get pregnant with twins but MC at about 10wks with only retrieving 3 eggs (TW over) ...hoping I'll be more successful on this 4th cycle of IVF.. Had my ER yesterday and got 10 eggs but one looks wonky so we'll say 9...hoping this latest protocol is the miracle one for me...i definitely responded better. Just proves that protocols do make a difference, best of luck!
@Msymmers922: I'm glad you have a great plan ahead! I've been close to using donor sperm myself. And I'm the one that had issue with it not OH. He thinks maybe younger sperm is the way to go, and thought maybe there was a genetic issue even though he already has healthy children. I know its tough and I'm not out of the woods until I actually bring home a baby right. Just remember donor or not its still your child together, its only science. I don't think its anything you really get past you just have to figure out how to mange and deal. Same thing I have to tell myself about the MC. Hoping your next cycle is magical for you!
AFM: ER was yesterday and I was really in more pain this time, so dizzy and quizzy. Ok good news is we got 10 out woohoo, one already looks wonky so he's considering that I got 9. I will say this time really was way more uncomfortable. The Anesthesiologist was super nice and gave me some pain meds. Hoping I got some winners in there!!! I wish this was the first cycle. They let OH sit with me after so that was nice! Perks to being last on a Sunday.
You'll all appreciate this, my RE was laughing that I was barely a wake and the first thing I asked was did we get any, how many EGGS
I gotta one track mind for sure!! Not sure how many were actually mature as he didn't say. Hoping to get my fertilization report any minute, fingers crossed!
History of TTC in spoiler box
TTC since 2014 Unexplained Infertility - but I am 40...Low AMH .30 7 - IUI (50mg-150mg Clomid) Feb - August 2016 all BFN IVF#1 August 2016 (Antagonist protocol 4/5 eggs) Cancelled cycle RE thought I would get at least 10. IVF#2 Sept 2016 (microdose luporn pro - disappearing follies, ONLY ONE, convert to IUI) BFN IVF#3 November 2016 (4 ER, 3 F, 3DT)-BFP with TWINS // MC both at almost 10wks IVF#4 March 2017 //EPP (10 ER (1 wonky so 9 ER) 7F, 3B (5AB, (2)5BB) PGS tested- ALL abnormal IVF#5 April 2017 // EPP (7 ER, 7F yes! 6B) 2/5 day 4/6 day - 2 PGS normal! yes!! IVF#6 May 2017 // Antagonist didn't have time for Estrogen Priming...(4 ER, 3 F, 3B) (5AB, (2) 5BB) 2 PGS normal, yes!! IVF#7 June 2017 // EPP praying this is it and then on to an FET!
@hopeful_mom that is a great number! Fingers crossed they all continue to grow! Will you be doing a fresh transfer or freezing and doing PGS? Or will it depend on the final number at day 5?
@cashewchicken I'm so sorry to hear everything you've been through. I had the same thoughts after not being successful with IUIs "Oh IVF will work!" While I was lucky to get 8 frozen embryos from my first retrieval, I've transferred 4 of those with no success and had 2 (possible 3) FET cycles canceled due to my lining not responding. I really hope this new protocol works for you!
@msymmers922 we haven't had to deal with donor eggs or sperm but we may have to use a gestational carrier and I think anytime you have to face the reality that you and your DH don't 100% get to go through the "normal" process of getting pregnant is so difficult. You really have to take time to grieve that loss (not having it be your DH's biological child; not being your biological child; not being pregnant yourself) and start to change the way you think about it. I think like @radmom27 said, as soon as you see that heartbeat or hold that baby in your arms, it won't really matter how you came to that place, only that you finally made it.
AFM - Well, I think this cycle will be canceled. Did Letrozole this round, hoping that growing a follicle(s) would naturally increase my lining, but had my second monitoring appointment today and not even one follicle has started to grow. This is two cycles in a row that not one follicle grew, and I've never had that issue before. The only thing I can think of is that I went off my medication for high prolactin since my levels had come down and now two cycles canceled. I'm thinking there might be something there (high prolactin inhibits the growth of follicles). I'll be following up with my regular endocrinologist to get repeat labs, but usually she wants me off ALL meds for at least 2-3 weeks to be sure there's nothing interfering with the results. Part of me is saying okay, we tried, let's move on to gestational carrier now, but another part of me is saying, did we really give it our BEST shot, if some of my levels weren't normal?
@mtpbadger- good to hear from you always but saddened to hear your update gosh you have just been on such a hard journey. I was so hoping this would be the one! I hear you about not wanting to move on until you are sure you have given I t your all... is there anyway you can start the carrier process while still trying to get your lining ready one more time? Not sure how long it takes but guessing it probably takes a few months to find someone and get all the legal done. If you still haven't gotten your lining to cooperate by the time it's all good for carrier, then you know it's time for that?... now if only our badgers hadn't lost in OT there would have been something to look forward too!
History in Spoiler
Age: 32 (same with DH). Together since 2006, Married June 2013 and TTC since August 2015 Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive) March-May 2016: 1 TI and 2 IUIs- BFN June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary. August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze ), BFN May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid Nov 2017- Hysterscopy to remove polyp Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone Apr 2018- DE FET cancelled for lining issues Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin Baby Born born early @ 33.5 weeks due to Pre-e Back for # 2!
@jamieh2000 shockingly my RE called yesterday afternoon and said I'm not out quite yet - she's having me take another 5 days of Letrozole at a higher dose to see if that will jump start anything. After talking with DH last night, if this cycle doesn't work, I will let my body take a break and we will start the process for a GC and then maybe try once more to get my lining up. My RE said the GC process can take up to 6-8 months, if not longer, between the matching, psychological and medical screenings, legal contracts, etc. Thankfully DH is willing to take the reins on the research b/c I would be overwhelmed.
I am so glad I didn't stay up to watch the Badger game! (It only started at 10pm EST) b/c I would have been devastated. They had a good run though! I'm now counting down until Badger football starts!
@mtpbadger- that's great you aren't out yet!! And it sounds like you have a good plan moving forward too. What a long hard road we are on, hopefully reaching out goal soon!! Please keep us posted!
i didn't stay up either! Work has been crazy and I'm lucky to make it to 10pm on a Friday these days!
History in Spoiler
Age: 32 (same with DH). Together since 2006, Married June 2013 and TTC since August 2015 Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive) March-May 2016: 1 TI and 2 IUIs- BFN June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary. August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze ), BFN May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid Nov 2017- Hysterscopy to remove polyp Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone Apr 2018- DE FET cancelled for lining issues Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin Baby Born born early @ 33.5 weeks due to Pre-e Back for # 2!
@mtpbadger- glad you can still sees where this cycle takes you! Love that OH is so involved as it should be!! You need a lil less stress in ur life for sure!! It's not a bad idea to start the process of that especially if it can take a while....this way ur always moving forward toward that miracle!!
Egg Update 7 of the 10 fertilized, I knew one was already wonky but I wonder what happened with the other 2 as they didn't mention if they were all mature.
My day 3 report is in and of course I was a lil confused ha!! The 7 are still growing but it seems 5 are really growing strong...praying they can make it to blasts!! Have 4 at 8AB, an 8A, 5BC and 4BC but its a 1PN. Our eggs I believe are suppose to be a 2PN...so not to confident on that one. We'll get another report on Friday. I'm trying to stay positive but its tough!! Its hard to except every egg isn't great and doesn't fertilize! Who knows but its just added stress we dont need!
History of TTC in spoiler box
TTC since 2014 Unexplained Infertility - but I am 40...Low AMH .30 7 - IUI (50mg-150mg Clomid) Feb - August 2016 all BFN IVF#1 August 2016 (Antagonist protocol 4/5 eggs) Cancelled cycle RE thought I would get at least 10. IVF#2 Sept 2016 (microdose luporn pro - disappearing follies, ONLY ONE, convert to IUI) BFN IVF#3 November 2016 (4 ER, 3 F, 3DT)-BFP with TWINS // MC both at almost 10wks IVF#4 March 2017 //EPP (10 ER (1 wonky so 9 ER) 7F, 3B (5AB, (2)5BB) PGS tested- ALL abnormal IVF#5 April 2017 // EPP (7 ER, 7F yes! 6B) 2/5 day 4/6 day - 2 PGS normal! yes!! IVF#6 May 2017 // Antagonist didn't have time for Estrogen Priming...(4 ER, 3 F, 3B) (5AB, (2) 5BB) 2 PGS normal, yes!! IVF#7 June 2017 // EPP praying this is it and then on to an FET!
@hopeful_mom that's great you still have 7 growing!! I think waiting for the updates for the embryos was the worst part of everything. Hopefully the two that are a little behind just need an extra day or two to catch up to the other 5!! Hopefully you can try and stay busy/distracted until Friday!
@mtpbadger Crossing my fingers that the Letrazole does its job and that you can move forward! @Hopeful_mom Sounds like a great fert report!! Those are some great numbers!! I like seeing good news here.
TTC since August 2014
Me: 41, Him: 43
DX: Unexplained secondary infertility
History: Multiple months of Clomid/Femara End of March 2015: BFP with Femara! Saw heartbeat at 5.5 weeks. M/C at 11 weeks Multiple more months of Femara IUI #1 with Femara and Follistem 75 units: BFN IUI #2 with Follistem 150 units: BFN Dec 2015: 1st IVF. 10 eggs retrieved with 8 eggs fertilized. 5 day transfer of two embryos with 2 frozen embies. BFN January 2016: FET #1 2 embryos: BFN March 2016: 2nd IVF cycle. 4 eggs retrieved with 2 fertilized. Quick two day transfer of both embryos: BFN April/May 2016 IVF #3. 11 eggs retrieved. 10 mature. 7 fertilized. 2 5AA blasts transferred 5/11/2016 BFN September 2016 IVF #4: 17 follicles growing, premature ovulation through Cetrotide. Retrieval cancelled. April 2017 IVF #5: 9 follicles growing, 6 eggs retrieved with 5 fertilized. Transfer of three blasts. BFN June 2017: IVF #6: 2 follicles growing, 5 eggs retrieved with 5 fertilized. Transfer of 5 3-day embryos. Chemical pregnancy. BFN Nov/Dec 2017: Donor egg cycle. 33 eggs retrieved, 26 mature. 26 fertilized.
@mtpbadger I'm hoping they catch up but I guess I'm being realistic too. I was planning on doing banking and it looks like I'll be sticking to that plan. When you do testing and banking. They take the sample before the freeze and then save that to go with the next batch you produce....g-d willing
radmom27 thanks just keep hoping they continue! How are you?? Where are you at?
History of TTC in spoiler box
TTC since 2014 Unexplained Infertility - but I am 40...Low AMH .30 7 - IUI (50mg-150mg Clomid) Feb - August 2016 all BFN IVF#1 August 2016 (Antagonist protocol 4/5 eggs) Cancelled cycle RE thought I would get at least 10. IVF#2 Sept 2016 (microdose luporn pro - disappearing follies, ONLY ONE, convert to IUI) BFN IVF#3 November 2016 (4 ER, 3 F, 3DT)-BFP with TWINS // MC both at almost 10wks IVF#4 March 2017 //EPP (10 ER (1 wonky so 9 ER) 7F, 3B (5AB, (2)5BB) PGS tested- ALL abnormal IVF#5 April 2017 // EPP (7 ER, 7F yes! 6B) 2/5 day 4/6 day - 2 PGS normal! yes!! IVF#6 May 2017 // Antagonist didn't have time for Estrogen Priming...(4 ER, 3 F, 3B) (5AB, (2) 5BB) 2 PGS normal, yes!! IVF#7 June 2017 // EPP praying this is it and then on to an FET!
@Hopeful_mom I'm in my last week of estrogen priming and am waiting for my period to start stims. Crossing my fingers that things go well this time and that I don't ovulate through my Cetrotide. My doctor doesn't have a great plan to prevent that from happening. Keep us posted on your Friday report!!
TTC since August 2014
Me: 41, Him: 43
DX: Unexplained secondary infertility
History: Multiple months of Clomid/Femara End of March 2015: BFP with Femara! Saw heartbeat at 5.5 weeks. M/C at 11 weeks Multiple more months of Femara IUI #1 with Femara and Follistem 75 units: BFN IUI #2 with Follistem 150 units: BFN Dec 2015: 1st IVF. 10 eggs retrieved with 8 eggs fertilized. 5 day transfer of two embryos with 2 frozen embies. BFN January 2016: FET #1 2 embryos: BFN March 2016: 2nd IVF cycle. 4 eggs retrieved with 2 fertilized. Quick two day transfer of both embryos: BFN April/May 2016 IVF #3. 11 eggs retrieved. 10 mature. 7 fertilized. 2 5AA blasts transferred 5/11/2016 BFN September 2016 IVF #4: 17 follicles growing, premature ovulation through Cetrotide. Retrieval cancelled. April 2017 IVF #5: 9 follicles growing, 6 eggs retrieved with 5 fertilized. Transfer of three blasts. BFN June 2017: IVF #6: 2 follicles growing, 5 eggs retrieved with 5 fertilized. Transfer of 5 3-day embryos. Chemical pregnancy. BFN Nov/Dec 2017: Donor egg cycle. 33 eggs retrieved, 26 mature. 26 fertilized.
@radmom27- we may end up being cycle buddies, assuming I ever get started with this cycle. I'm sure that is very stressful worrying about ovulating through the cetrocide, I am hope they will be watching you very closely as you get close? Like daily hopefully?
AFM, I am STILL in limbo... I took my last provera/estrace on sunday.. and just waiting for AF. I was feeling crampy yesterday and thought it was coming, and then nothing today! Has anyone else taken provera to get a cycle going? How long did it take for AF to come? I am sure I am sounding impatient, but this cycle has been almost 7 weeks now! I was supposed to be to transfer by this point
History in Spoiler
Age: 32 (same with DH). Together since 2006, Married June 2013 and TTC since August 2015 Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive) March-May 2016: 1 TI and 2 IUIs- BFN June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary. August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze ), BFN May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid Nov 2017- Hysterscopy to remove polyp Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone Apr 2018- DE FET cancelled for lining issues Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin Baby Born born early @ 33.5 weeks due to Pre-e Back for # 2!
@jamieh2000 I stopped provera on a Saturday and didn't start bleeding until the following Monday (8 days). Even then it was just spotting and took a few days for AF to actually show. In the past when I've taken it it usually took anywhere from 4-6 days on average so I had started getting worried but my RE said it can take up to two weeks. Hopefully AF shows for you soon!
@mtpbadger- thank you for the quick response!! That does make me feel better. Hopefully it will be coming soon. This is just so hard after always ovulating super regularly. It makes me worried something else is now wrong with me Makes me have a new appreciation for everyone with irregular cycles. Never thought I would want AF this bad!
History in Spoiler
Age: 32 (same with DH). Together since 2006, Married June 2013 and TTC since August 2015 Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive) March-May 2016: 1 TI and 2 IUIs- BFN June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary. August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze ), BFN May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid Nov 2017- Hysterscopy to remove polyp Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone Apr 2018- DE FET cancelled for lining issues Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin Baby Born born early @ 33.5 weeks due to Pre-e Back for # 2!
@JamieH2000 I do hope that we end up being cycle buddies! Waiting for AF is so frustrating..she always comes when I don't want her to, but when I'm waiting for her...forget about it!
TTC since August 2014
Me: 41, Him: 43
DX: Unexplained secondary infertility
History: Multiple months of Clomid/Femara End of March 2015: BFP with Femara! Saw heartbeat at 5.5 weeks. M/C at 11 weeks Multiple more months of Femara IUI #1 with Femara and Follistem 75 units: BFN IUI #2 with Follistem 150 units: BFN Dec 2015: 1st IVF. 10 eggs retrieved with 8 eggs fertilized. 5 day transfer of two embryos with 2 frozen embies. BFN January 2016: FET #1 2 embryos: BFN March 2016: 2nd IVF cycle. 4 eggs retrieved with 2 fertilized. Quick two day transfer of both embryos: BFN April/May 2016 IVF #3. 11 eggs retrieved. 10 mature. 7 fertilized. 2 5AA blasts transferred 5/11/2016 BFN September 2016 IVF #4: 17 follicles growing, premature ovulation through Cetrotide. Retrieval cancelled. April 2017 IVF #5: 9 follicles growing, 6 eggs retrieved with 5 fertilized. Transfer of three blasts. BFN June 2017: IVF #6: 2 follicles growing, 5 eggs retrieved with 5 fertilized. Transfer of 5 3-day embryos. Chemical pregnancy. BFN Nov/Dec 2017: Donor egg cycle. 33 eggs retrieved, 26 mature. 26 fertilized.
@radmom27-@JamieH2000 u know i might end up being cycle buddies with u ladies Since I'm doing banking I assume that I should be starting once AF shows...but I"m suppose to be doing Estrogen priming so I"m not sure when thats suppose to happen. I asked the RE the same thing so hopefully she'll have an answer
History of TTC in spoiler box
TTC since 2014 Unexplained Infertility - but I am 40...Low AMH .30 7 - IUI (50mg-150mg Clomid) Feb - August 2016 all BFN IVF#1 August 2016 (Antagonist protocol 4/5 eggs) Cancelled cycle RE thought I would get at least 10. IVF#2 Sept 2016 (microdose luporn pro - disappearing follies, ONLY ONE, convert to IUI) BFN IVF#3 November 2016 (4 ER, 3 F, 3DT)-BFP with TWINS // MC both at almost 10wks IVF#4 March 2017 //EPP (10 ER (1 wonky so 9 ER) 7F, 3B (5AB, (2)5BB) PGS tested- ALL abnormal IVF#5 April 2017 // EPP (7 ER, 7F yes! 6B) 2/5 day 4/6 day - 2 PGS normal! yes!! IVF#6 May 2017 // Antagonist didn't have time for Estrogen Priming...(4 ER, 3 F, 3B) (5AB, (2) 5BB) 2 PGS normal, yes!! IVF#7 June 2017 // EPP praying this is it and then on to an FET!
@Hopeful_mom The more cycle buddies in the not my first rodeo club, the better!!!!
TTC since August 2014
Me: 41, Him: 43
DX: Unexplained secondary infertility
History: Multiple months of Clomid/Femara End of March 2015: BFP with Femara! Saw heartbeat at 5.5 weeks. M/C at 11 weeks Multiple more months of Femara IUI #1 with Femara and Follistem 75 units: BFN IUI #2 with Follistem 150 units: BFN Dec 2015: 1st IVF. 10 eggs retrieved with 8 eggs fertilized. 5 day transfer of two embryos with 2 frozen embies. BFN January 2016: FET #1 2 embryos: BFN March 2016: 2nd IVF cycle. 4 eggs retrieved with 2 fertilized. Quick two day transfer of both embryos: BFN April/May 2016 IVF #3. 11 eggs retrieved. 10 mature. 7 fertilized. 2 5AA blasts transferred 5/11/2016 BFN September 2016 IVF #4: 17 follicles growing, premature ovulation through Cetrotide. Retrieval cancelled. April 2017 IVF #5: 9 follicles growing, 6 eggs retrieved with 5 fertilized. Transfer of three blasts. BFN June 2017: IVF #6: 2 follicles growing, 5 eggs retrieved with 5 fertilized. Transfer of 5 3-day embryos. Chemical pregnancy. BFN Nov/Dec 2017: Donor egg cycle. 33 eggs retrieved, 26 mature. 26 fertilized.
@hopeful_mom- my guess would be that you get AF and then wait to ovulate and then so the priming, so a one monk break between retrievals. That's what I was doing after my last cycle... but this cycle has been 7 weeks instead of 4, so hopefully your body cooperates more than mine!
@radmom27- you are so right about AF! Perhaps ours will come on the same day and we will true cycle buddies. No signs of her yet for me so who knows!
History in Spoiler
Age: 32 (same with DH). Together since 2006, Married June 2013 and TTC since August 2015 Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive) March-May 2016: 1 TI and 2 IUIs- BFN June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary. August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze ), BFN May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid Nov 2017- Hysterscopy to remove polyp Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone Apr 2018- DE FET cancelled for lining issues Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin Baby Born born early @ 33.5 weeks due to Pre-e Back for # 2!
@Hopeful_mom- I'm sorry for your loss. I'm happy to hear that your 7 embryos are thriving though. Hope one of them ends up being the one. Your testimony of changing protocols making a difference is really encouraging. Looking forward to the new protocol.
@mtpbadger-I'm sorry that your body is not cooperating. But you're not out yet, and hopefully extra days on letrozole does the trick.
AFM- started lupron injections yesterday, and have one more bcp to take tomorrow. Will have the baseline ultrasound next Monday and if all goes well, I'm going to start stimulation injections next Friday!
Me: 41 DH: 46 Unexplained infertility/AMA, polycystic ovaries, insulin resistance FET#1(July 2017): eSET of first of 4 PGS-normal embryos, DS born 3/30/2018 FET#2(Oct/Nov 2019): eSET
Just got a voice message from my RE letting me know she will be out of the office next week and gave me the contact for the Dr's covering for her.
She believes this round will be converted to an IUI. She staffed my case with some other RE's in the practice and said if this round doesn't work, she wants to try putting me on Metformin and Ovasitol (supplement) for a month to see if my lining reacts better being on those. Even though I don't have the "standard" PCOS symptoms, other RE's in the practice have seen some improvement in lining being placed on these two things. I guess it's worth a shot!
mtpbadger Everything is worth a shot!! And at least there are still some things to try. I know all the trips to the dr for tests and such is not fun...but everyone says in the end we'l forget it all once we get our miracle
HI Ladies!! Got my report.
I want to say I'm happy but I think right now I'm just relieved that I have something. So far I have a 5AA and 5AB that have made it to freeze. One was through icsi and the other regular. MAYBE I can get another one or two tomorrow PRAYING that it does happen. Just very worried about only having 2 for testing you know. They are super quality I'm told so trying to believe in that right now. This process is so expensive!! Doing it this way its gonna be at least 30/50k and so far have hopes of just 2 ugh....I'm beyond worried today! I know theres nothing I can do, but I do wonder if I just shouldve done the fresh cycle transfer. Some embryos do grow better inside why they do the 3dt. Last cycle I got 3 and pregnant with twins. This cycle I had 9 and so far back to 2 and hopes they're normal!
My brain is going a mile a minute, I'm tempted next cycle to try and do a fresh transfer and then hopefully test whatever else makes it. I know it sounds crazy but if others dont come through tomorrow then I just wonder if my lil embabies are happier being in me then out of me....
History of TTC in spoiler box
TTC since 2014 Unexplained Infertility - but I am 40...Low AMH .30 7 - IUI (50mg-150mg Clomid) Feb - August 2016 all BFN IVF#1 August 2016 (Antagonist protocol 4/5 eggs) Cancelled cycle RE thought I would get at least 10. IVF#2 Sept 2016 (microdose luporn pro - disappearing follies, ONLY ONE, convert to IUI) BFN IVF#3 November 2016 (4 ER, 3 F, 3DT)-BFP with TWINS // MC both at almost 10wks IVF#4 March 2017 //EPP (10 ER (1 wonky so 9 ER) 7F, 3B (5AB, (2)5BB) PGS tested- ALL abnormal IVF#5 April 2017 // EPP (7 ER, 7F yes! 6B) 2/5 day 4/6 day - 2 PGS normal! yes!! IVF#6 May 2017 // Antagonist didn't have time for Estrogen Priming...(4 ER, 3 F, 3B) (5AB, (2) 5BB) 2 PGS normal, yes!! IVF#7 June 2017 // EPP praying this is it and then on to an FET!
@mtpbadger- you sound like you have a really great RE/clininc! So glad they all talk and keep trying to come up with ideas for you! Hopefully this next protocol will work and maybe you will be one of the first of a new break through for lining protocols When will they decide about IUI?
History in Spoiler
Age: 32 (same with DH). Together since 2006, Married June 2013 and TTC since August 2015 Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive) March-May 2016: 1 TI and 2 IUIs- BFN June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary. August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze ), BFN May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid Nov 2017- Hysterscopy to remove polyp Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone Apr 2018- DE FET cancelled for lining issues Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin Baby Born born early @ 33.5 weeks due to Pre-e Back for # 2!
@jamieh2000 I adore my RE! Even though it's a large clinic and I don't often see her for ultrasounds or even the retrieval/transfer, she calls with updates and always staffs my case with others and has different ideas. All the doctors and most of the nurses have been fabulous!
I go back on Wed for us/bw. I actually got an email from my nurse saying to order the ovasitol right away and I'll have to get some labs drawn before starting the metformin.
@hopeful_mom fingers crossed that the other two make it to freeze tomorrow! If it makes you feel any better, I had several day 6s make it and even a day 7, So they still have a chance!!
@mtpbadger- I hope your RE prescribed you the extended release version of metformin, not the regular one. I've heard of people having serious GI issues with the regular version, less so with extended release. I've been on metformin for over a year now and I take the extended release and I have not had a single issue with it.
@hopeful_mom- congrats on two beautiful embies and hope you get two more tomorrow. I've read some papers out there, and assuming that the culture technique is fine, the eggs that don't make the cut by day 5 are usually due to aneuploidy (chromosomal problems). So while it may be disappointing that there aren't as many day 5 embryos left, at least you know that the ones that made it have a higher chance of it being normal! But at the same time, I do understand your desire to do a day 3 transfer. I've started this IVF journey with embryo banking in mind (target: 5-6 PGS normal embryos), but after two cycles and 0 PGS normal embryos, I'm tempted to transfer just whatever I can get and hope for the best... But for me, my odds of getting a chromosomally-normal embryo is so low that I have to test anyway. Sigh.
Me: 41 DH: 46 Unexplained infertility/AMA, polycystic ovaries, insulin resistance FET#1(July 2017): eSET of first of 4 PGS-normal embryos, DS born 3/30/2018 FET#2(Oct/Nov 2019): eSET
@mtpbadger- that does make me feel better and gives me some hope, thank u!
@cashewchicken thanks for the info! I think its the fact that i did get pregnant with 2 out of the 3 that I'm starting to lose hope in this prolonged process. I wouldve gambles without the test as they say the good ones are the ones that are suppose to stick. Its my OH my MC was terrible and lost so much blood...it was a horrible ordeal that he can't see me go through it again. Not that i want too but nothing is 100%. Thats whats freaking me out too is reading about people that MC where the baby stops growing and its PGS normal. How is that even possible? Its such a miracle and it amazes me how it just happens so easily for others. I'm all OOP and yes you want this so bad but where do u draw the line. Down payment for a house...I hate to look at the expense but knowing 40k was all for nothing and ur at it again is hard when all those bills start coming in...Hoping I'll get some good news tomorrow! how many of your made it to day 5? Its very scary but still works for many. Your body is suppose to be able to tell which are the healthy embryos and keep them. I understand ur struggle, why we're all here...but I still have my angry days! I think i was overly excited to finally have a better response but in the end is looking to be the same outcome is my concern too.
History of TTC in spoiler box
TTC since 2014 Unexplained Infertility - but I am 40...Low AMH .30 7 - IUI (50mg-150mg Clomid) Feb - August 2016 all BFN IVF#1 August 2016 (Antagonist protocol 4/5 eggs) Cancelled cycle RE thought I would get at least 10. IVF#2 Sept 2016 (microdose luporn pro - disappearing follies, ONLY ONE, convert to IUI) BFN IVF#3 November 2016 (4 ER, 3 F, 3DT)-BFP with TWINS // MC both at almost 10wks IVF#4 March 2017 //EPP (10 ER (1 wonky so 9 ER) 7F, 3B (5AB, (2)5BB) PGS tested- ALL abnormal IVF#5 April 2017 // EPP (7 ER, 7F yes! 6B) 2/5 day 4/6 day - 2 PGS normal! yes!! IVF#6 May 2017 // Antagonist didn't have time for Estrogen Priming...(4 ER, 3 F, 3B) (5AB, (2) 5BB) 2 PGS normal, yes!! IVF#7 June 2017 // EPP praying this is it and then on to an FET!
@cashewchicken thanks for the heads up that there is a regular version and extended release! I will talk with my Dr once she's back in town about which one she is prescribing.
AFM: I went in for BW to see if my levels were ready to start estrogen priming but as I assumed they are not. I was glad I went in so I could find a nurse to help get me answers on my frosties! So one more frostie is joining the party yay!! So I have one 5AB (reg fert) and two 5BB (icsi) I know I should be happy with 3, I'll be even happier when they all come back pgs normal Praying this next cycle can be as successful or maybe a lil more
History of TTC in spoiler box
TTC since 2014 Unexplained Infertility - but I am 40...Low AMH .30 7 - IUI (50mg-150mg Clomid) Feb - August 2016 all BFN IVF#1 August 2016 (Antagonist protocol 4/5 eggs) Cancelled cycle RE thought I would get at least 10. IVF#2 Sept 2016 (microdose luporn pro - disappearing follies, ONLY ONE, convert to IUI) BFN IVF#3 November 2016 (4 ER, 3 F, 3DT)-BFP with TWINS // MC both at almost 10wks IVF#4 March 2017 //EPP (10 ER (1 wonky so 9 ER) 7F, 3B (5AB, (2)5BB) PGS tested- ALL abnormal IVF#5 April 2017 // EPP (7 ER, 7F yes! 6B) 2/5 day 4/6 day - 2 PGS normal! yes!! IVF#6 May 2017 // Antagonist didn't have time for Estrogen Priming...(4 ER, 3 F, 3B) (5AB, (2) 5BB) 2 PGS normal, yes!! IVF#7 June 2017 // EPP praying this is it and then on to an FET!
@Hopeful_mom- congrats on 3 frosties! Hope they are normal! MC is scary, and I hope you and your hubby will never have to go through that again. MC with PGS normal baby can happen too, I guess it just goes to show that there are several contributing factors to MC. Tests aren't 100% either. At least with PGS testing, there is a good chance that you are taking chromosomal issues out of your pregnancy, and for me, at my age, I'll take it.
As for how many of mine made it to day 5... my first cycle, a contamination killed all the embryos so I had 0. My second, 5 made it to blastocyst, biopsied and sent for testing, and all 5 came back abnormal. I'm hoping the reason they were abnormal was because many of the eggs had to be matured in vitro overnight. Apparently in vitro egg maturation results in higher % of chromosomally abnormal eggs.
Me: 41 DH: 46 Unexplained infertility/AMA, polycystic ovaries, insulin resistance FET#1(July 2017): eSET of first of 4 PGS-normal embryos, DS born 3/30/2018 FET#2(Oct/Nov 2019): eSET
Re: Not my first IVF rodeo
@Hopeful_mom I completely misunderstood! Sorry!
CP #1- due April 2017 lost 5.5 weeks
cp #2- due May 2017 lost at 4.5 weeks
iUI #1- BFN
IUI #2-BFN
IVF#1- transfer 2- BFP! Due October 2017 c/p#3 lost at 3.5 weeks
Unexplained Infertility - but I am 40...Low AMH .30
7 - IUI (50mg-150mg Clomid) Feb - August 2016 all BFN
IVF#1 August 2016 (Antagonist protocol 4/5 eggs) Cancelled cycle
IVF#2 Sept 2016 (microdose luporn pro - disappearing follies, ONLY ONE, convert to IUI) BFN
IVF#3 November 2016 (4 ER, 3 F, 3DT)-BFP
IVF#4 March 2017 //EPP (10 ER (1 wonky so 9 ER) 7F, 3B (5AB, (2)5BB) PGS tested- ALL abnormal
IVF#5 April 2017 // EPP (7 ER, 7F yes! 6B) 2/5 day 4/6 day - 2 PGS normal! yes!!
IVF#6 May 2017 // Antagonist didn't have time for Estrogen Priming...(4 ER, 3 F, 3B) (5AB, (2) 5BB) 2 PGS normal, yes!!
IVF#7 June 2017 // EPP praying this is it and then on to an FET!
Me: DOR, poor egg quality, MTHFR
DH: MFI
TTC since 3/2014
2015: 3 IUI's-BFN
12/2015: 1st IVF cycle-(9 follicles retrieved, 5 mature, 3 fertilized w/ICSI, transferred 1 excellent and 1 good embryo on day 3)-chemical pregnancy
3/2016: 2nd IVF cycle- canceled (3 follicles retrieved, 3 mature, all fertilized w/ICSI, 1 fragmented, 2 arrested)
3/2016: RE suggested donor eggs- taking an ivf break and to supplement
9/2016: 3rd ivf cycle-cancelled due to early ovulation
Oct./Nov 2016: 4th ivf cycle- EPP-AFC:5, retrieved 10, 10 mature, 8 fertilized with ICSI, 6 blastocysts biopsied and frozen. 3 CCS normal embryos
1/18/17: beta #1-104
1/20/17: beta #2-174
2/2/17: first u/s, heartbeat of 107 at 6w1d
7/20/17: baby boy born at 30+3 via emergency c-section
CP #1- due April 2017 lost 5.5 weeks
cp #2- due May 2017 lost at 4.5 weeks
iUI #1- BFN
IUI #2-BFN
IVF#1- transfer 2- BFP! Due October 2017 c/p#3 lost at 3.5 weeks
Unexplained Infertility - but I am 40...Low AMH .30
7 - IUI (50mg-150mg Clomid) Feb - August 2016 all BFN
IVF#1 August 2016 (Antagonist protocol 4/5 eggs) Cancelled cycle
IVF#2 Sept 2016 (microdose luporn pro - disappearing follies, ONLY ONE, convert to IUI) BFN
IVF#3 November 2016 (4 ER, 3 F, 3DT)-BFP
IVF#4 March 2017 //EPP (10 ER (1 wonky so 9 ER) 7F, 3B (5AB, (2)5BB) PGS tested- ALL abnormal
IVF#5 April 2017 // EPP (7 ER, 7F yes! 6B) 2/5 day 4/6 day - 2 PGS normal! yes!!
IVF#6 May 2017 // Antagonist didn't have time for Estrogen Priming...(4 ER, 3 F, 3B) (5AB, (2) 5BB) 2 PGS normal, yes!!
IVF#7 June 2017 // EPP praying this is it and then on to an FET!
I've now had 2 IVF cycles and oh boy, I never thought that I will end up with no normal embryos. I've had 6 IUI cycles prior to the IVF cycles and when all 6 IUIs ended with BFNs, I thought, hey, there's always IVF. Surely IVF will work, because the success rate is so high!
Well... that wasn't the case. Not for me anyways. My problem seems to be that the majority of eggs are immature. I've now had two luteal stimulation protocols and both cycles produced low % of mature eggs. The first cycle was a little less than 50%, the second cycle was only 30% mature. After two consecutive failures, my RE acknowledged that the luteal stimulation protocol doesn't work for me. So for the upcoming cycle, we are trying the traditional IVF protocol, the long agonist protocol. Hoping that will yield higher % of mature eggs, and also normal embryos. Like some of you, I'm also banking embryos as DH and I want two kids, if possible.
Unexplained infertility/AMA, polycystic ovaries, insulin resistance
FET#1(July 2017): eSET of first of 4 PGS-normal embryos, DS born 3/30/2018
FET#2(Oct/Nov 2019): eSET
wish me luck!
xx
cashewchicken - I am glad your RE is changing the protocol. That can make all the difference. My first IVF was cancelled for poor response and the second I only got 2 eggs. My third I did Estrogen priming with antagonist and I got 12 eggs (8 mature)! Hopefully the new protocol will be all you need! Keep us posted!
@gwinnyblack- good luck! I am hoping to start round 4 soon too. Hoping for lots of eggs for yoU!
Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive)
March-May 2016: 1 TI and 2 IUIs- BFN
June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary.
August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN
Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN
January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze
May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline
Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid
Nov 2017- Hysterscopy to remove polyp
Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated
Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone
Apr 2018- DE FET cancelled for lining issues
Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin
Baby Born born early @ 33.5 weeks due to Pre-e
Back for # 2!
Multiple months of Clomid/Femara
End of March 2015: BFP with Femara! Saw heartbeat at 5.5 weeks. M/C at 11 weeks
Multiple more months of Femara
IUI #1 with Femara and Follistem 75 units: BFN
IUI #2 with Follistem 150 units: BFN
Dec 2015: 1st IVF. 10 eggs retrieved with 8 eggs fertilized. 5 day transfer of two embryos with 2 frozen embies. BFN
January 2016: FET #1 2 embryos: BFN
March 2016: 2nd IVF cycle. 4 eggs retrieved with 2 fertilized. Quick two day transfer of both embryos: BFN
April/May 2016 IVF #3. 11 eggs retrieved. 10 mature. 7 fertilized. 2 5AA blasts transferred 5/11/2016 BFN
September 2016 IVF #4: 17 follicles growing, premature ovulation through Cetrotide. Retrieval cancelled.
April 2017 IVF #5: 9 follicles growing, 6 eggs retrieved with 5 fertilized. Transfer of three blasts. BFN
June 2017: IVF #6: 2 follicles growing, 5 eggs retrieved with 5 fertilized. Transfer of 5 3-day embryos. Chemical pregnancy. BFN
Nov/Dec 2017: Donor egg cycle. 33 eggs retrieved, 26 mature. 26 fertilized.
@JamieH2000: I'm hoping the new protocol makes a huge difference. If it doesn't, then at least we will know the cause of my infertility... I was hoping to change the protocol for the second cycle, but the doctor thought it would be best to repeat it... At least this is something to look forward to. Hoping your #4 is it!
@Msymmers922: I am still trying with my own eggs, but I am open to donor eggs as well, if egg quality turns out to be an issue we can't overcome. A close friend of mine recently tried IVF with donor eggs and she's in early stages of her pregnancy. For her, she was diagnosed with diminished ovarian reserve, and the chance of her having children with her own eggs was slim to none. Since she and her husband both wanted kids, the choice was either adopting or using donor eggs. Her husband was initially hesitant (like you), but she really wanted to, as the baby will be at least genetically linked to her husband, and she will carry and deliver the child. I think the difficulty of the adoption process also made them try the donor egg route first.
Unexplained infertility/AMA, polycystic ovaries, insulin resistance
FET#1(July 2017): eSET of first of 4 PGS-normal embryos, DS born 3/30/2018
FET#2(Oct/Nov 2019): eSET
CP #1- due April 2017 lost 5.5 weeks
cp #2- due May 2017 lost at 4.5 weeks
iUI #1- BFN
IUI #2-BFN
IVF#1- transfer 2- BFP! Due October 2017 c/p#3 lost at 3.5 weeks
thanks I had it already
feel great right now
cashewchicken sorry ur having such a hard time and find yourself here, its not easy indeed! Like @jamieh2000 mentioned the right protocol can be all you need. I did 6 IUIs as well, I even double down on some IUI cycle with some great samples and still bfn
@Msymmers922: I'm glad you have a great plan ahead! I've been close to using donor sperm myself. And I'm the one that had issue with it not OH. He thinks maybe younger sperm is the way to go, and thought maybe there was a genetic issue even though he already has healthy children. I know its tough and I'm not out of the woods until I actually bring home a baby right. Just remember donor or not its still your child together, its only science. I don't think its anything you really get past you just have to figure out how to mange and deal. Same thing I have to tell myself about the MC. Hoping your next cycle is magical for you!
Unexplained Infertility - but I am 40...Low AMH .30
7 - IUI (50mg-150mg Clomid) Feb - August 2016 all BFN
IVF#1 August 2016 (Antagonist protocol 4/5 eggs) Cancelled cycle
IVF#2 Sept 2016 (microdose luporn pro - disappearing follies, ONLY ONE, convert to IUI) BFN
IVF#3 November 2016 (4 ER, 3 F, 3DT)-BFP
IVF#4 March 2017 //EPP (10 ER (1 wonky so 9 ER) 7F, 3B (5AB, (2)5BB) PGS tested- ALL abnormal
IVF#5 April 2017 // EPP (7 ER, 7F yes! 6B) 2/5 day 4/6 day - 2 PGS normal! yes!!
IVF#6 May 2017 // Antagonist didn't have time for Estrogen Priming...(4 ER, 3 F, 3B) (5AB, (2) 5BB) 2 PGS normal, yes!!
IVF#7 June 2017 // EPP praying this is it and then on to an FET!
@hopeful_mom that is a great number! Fingers crossed they all continue to grow! Will you be doing a fresh transfer or freezing and doing PGS? Or will it depend on the final number at day 5?
@cashewchicken I'm so sorry to hear everything you've been through. I had the same thoughts after not being successful with IUIs "Oh IVF will work!" While I was lucky to get 8 frozen embryos from my first retrieval, I've transferred 4 of those with no success and had 2 (possible 3) FET cycles canceled due to my lining not responding. I really hope this new protocol works for you!
@msymmers922 we haven't had to deal with donor eggs or sperm but we may have to use a gestational carrier and I think anytime you have to face the reality that you and your DH don't 100% get to go through the "normal" process of getting pregnant is so difficult. You really have to take time to grieve that loss (not having it be your DH's biological child; not being your biological child; not being pregnant yourself) and start to change the way you think about it. I think like @radmom27 said, as soon as you see that heartbeat or hold that baby in your arms, it won't really matter how you came to that place, only that you finally made it.
AFM - Well, I think this cycle will be canceled. Did Letrozole this round, hoping that growing a follicle(s) would naturally increase my lining, but had my second monitoring appointment today and not even one follicle has started to grow. This is two cycles in a row that not one follicle grew, and I've never had that issue before. The only thing I can think of is that I went off my medication for high prolactin since my levels had come down and now two cycles canceled. I'm thinking there might be something there (high prolactin inhibits the growth of follicles). I'll be following up with my regular endocrinologist to get repeat labs, but usually she wants me off ALL meds for at least 2-3 weeks to be sure there's nothing interfering with the results. Part of me is saying okay, we tried, let's move on to gestational carrier now, but another part of me is saying, did we really give it our BEST shot, if some of my levels weren't normal?
Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive)
March-May 2016: 1 TI and 2 IUIs- BFN
June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary.
August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN
Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN
January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze
May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline
Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid
Nov 2017- Hysterscopy to remove polyp
Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated
Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone
Apr 2018- DE FET cancelled for lining issues
Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin
Baby Born born early @ 33.5 weeks due to Pre-e
Back for # 2!
@jamieh2000 shockingly my RE called yesterday afternoon and said I'm not out quite yet - she's having me take another 5 days of Letrozole at a higher dose to see if that will jump start anything. After talking with DH last night, if this cycle doesn't work, I will let my body take a break and we will start the process for a GC and then maybe try once more to get my lining up. My RE said the GC process can take up to 6-8 months, if not longer, between the matching, psychological and medical screenings, legal contracts, etc. Thankfully DH is willing to take the reins on the research b/c I would be overwhelmed.
I am so glad I didn't stay up to watch the Badger game! (It only started at 10pm EST) b/c I would have been devastated. They had a good run though! I'm now counting down until Badger football starts!
i didn't stay up either! Work has been crazy and I'm lucky to make it to 10pm on a Friday these days!
Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive)
March-May 2016: 1 TI and 2 IUIs- BFN
June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary.
August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN
Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN
January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze
May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline
Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid
Nov 2017- Hysterscopy to remove polyp
Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated
Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone
Apr 2018- DE FET cancelled for lining issues
Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin
Baby Born born early @ 33.5 weeks due to Pre-e
Back for # 2!
Egg Update
7 of the 10 fertilized, I knew one was already wonky but I wonder what happened with the other 2 as they didn't mention if they were all mature.
My day 3 report is in and of course I was a lil confused ha!! The 7 are still growing but it seems 5 are really growing strong...praying they can make it to blasts!!
Have 4 at 8AB, an 8A, 5BC and 4BC but its a 1PN. Our eggs I believe are suppose to be a 2PN...so not to confident on that one. We'll get another report on Friday. I'm trying to stay positive but its tough!! Its hard to except every egg isn't great and doesn't fertilize! Who knows but its just added stress we dont need!
Unexplained Infertility - but I am 40...Low AMH .30
7 - IUI (50mg-150mg Clomid) Feb - August 2016 all BFN
IVF#1 August 2016 (Antagonist protocol 4/5 eggs) Cancelled cycle
IVF#2 Sept 2016 (microdose luporn pro - disappearing follies, ONLY ONE, convert to IUI) BFN
IVF#3 November 2016 (4 ER, 3 F, 3DT)-BFP
IVF#4 March 2017 //EPP (10 ER (1 wonky so 9 ER) 7F, 3B (5AB, (2)5BB) PGS tested- ALL abnormal
IVF#5 April 2017 // EPP (7 ER, 7F yes! 6B) 2/5 day 4/6 day - 2 PGS normal! yes!!
IVF#6 May 2017 // Antagonist didn't have time for Estrogen Priming...(4 ER, 3 F, 3B) (5AB, (2) 5BB) 2 PGS normal, yes!!
IVF#7 June 2017 // EPP praying this is it and then on to an FET!
@Hopeful_mom Sounds like a great fert report!! Those are some great numbers!! I like seeing good news here.
Multiple months of Clomid/Femara
End of March 2015: BFP with Femara! Saw heartbeat at 5.5 weeks. M/C at 11 weeks
Multiple more months of Femara
IUI #1 with Femara and Follistem 75 units: BFN
IUI #2 with Follistem 150 units: BFN
Dec 2015: 1st IVF. 10 eggs retrieved with 8 eggs fertilized. 5 day transfer of two embryos with 2 frozen embies. BFN
January 2016: FET #1 2 embryos: BFN
March 2016: 2nd IVF cycle. 4 eggs retrieved with 2 fertilized. Quick two day transfer of both embryos: BFN
April/May 2016 IVF #3. 11 eggs retrieved. 10 mature. 7 fertilized. 2 5AA blasts transferred 5/11/2016 BFN
September 2016 IVF #4: 17 follicles growing, premature ovulation through Cetrotide. Retrieval cancelled.
April 2017 IVF #5: 9 follicles growing, 6 eggs retrieved with 5 fertilized. Transfer of three blasts. BFN
June 2017: IVF #6: 2 follicles growing, 5 eggs retrieved with 5 fertilized. Transfer of 5 3-day embryos. Chemical pregnancy. BFN
Nov/Dec 2017: Donor egg cycle. 33 eggs retrieved, 26 mature. 26 fertilized.
radmom27 thanks just keep hoping they continue! How are you?? Where are you at?
Unexplained Infertility - but I am 40...Low AMH .30
7 - IUI (50mg-150mg Clomid) Feb - August 2016 all BFN
IVF#1 August 2016 (Antagonist protocol 4/5 eggs) Cancelled cycle
IVF#2 Sept 2016 (microdose luporn pro - disappearing follies, ONLY ONE, convert to IUI) BFN
IVF#3 November 2016 (4 ER, 3 F, 3DT)-BFP
IVF#4 March 2017 //EPP (10 ER (1 wonky so 9 ER) 7F, 3B (5AB, (2)5BB) PGS tested- ALL abnormal
IVF#5 April 2017 // EPP (7 ER, 7F yes! 6B) 2/5 day 4/6 day - 2 PGS normal! yes!!
IVF#6 May 2017 // Antagonist didn't have time for Estrogen Priming...(4 ER, 3 F, 3B) (5AB, (2) 5BB) 2 PGS normal, yes!!
IVF#7 June 2017 // EPP praying this is it and then on to an FET!
Keep us posted on your Friday report!!
Multiple months of Clomid/Femara
End of March 2015: BFP with Femara! Saw heartbeat at 5.5 weeks. M/C at 11 weeks
Multiple more months of Femara
IUI #1 with Femara and Follistem 75 units: BFN
IUI #2 with Follistem 150 units: BFN
Dec 2015: 1st IVF. 10 eggs retrieved with 8 eggs fertilized. 5 day transfer of two embryos with 2 frozen embies. BFN
January 2016: FET #1 2 embryos: BFN
March 2016: 2nd IVF cycle. 4 eggs retrieved with 2 fertilized. Quick two day transfer of both embryos: BFN
April/May 2016 IVF #3. 11 eggs retrieved. 10 mature. 7 fertilized. 2 5AA blasts transferred 5/11/2016 BFN
September 2016 IVF #4: 17 follicles growing, premature ovulation through Cetrotide. Retrieval cancelled.
April 2017 IVF #5: 9 follicles growing, 6 eggs retrieved with 5 fertilized. Transfer of three blasts. BFN
June 2017: IVF #6: 2 follicles growing, 5 eggs retrieved with 5 fertilized. Transfer of 5 3-day embryos. Chemical pregnancy. BFN
Nov/Dec 2017: Donor egg cycle. 33 eggs retrieved, 26 mature. 26 fertilized.
AFM, I am STILL in limbo... I took my last provera/estrace on sunday.. and just waiting for AF. I was feeling crampy yesterday and thought it was coming, and then nothing today! Has anyone else taken provera to get a cycle going? How long did it take for AF to come? I am sure I am sounding impatient, but this cycle has been almost 7 weeks now! I was supposed to be to transfer by this point
Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive)
March-May 2016: 1 TI and 2 IUIs- BFN
June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary.
August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN
Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN
January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze
May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline
Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid
Nov 2017- Hysterscopy to remove polyp
Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated
Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone
Apr 2018- DE FET cancelled for lining issues
Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin
Baby Born born early @ 33.5 weeks due to Pre-e
Back for # 2!
Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive)
March-May 2016: 1 TI and 2 IUIs- BFN
June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary.
August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN
Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN
January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze
May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline
Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid
Nov 2017- Hysterscopy to remove polyp
Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated
Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone
Apr 2018- DE FET cancelled for lining issues
Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin
Baby Born born early @ 33.5 weeks due to Pre-e
Back for # 2!
Multiple months of Clomid/Femara
End of March 2015: BFP with Femara! Saw heartbeat at 5.5 weeks. M/C at 11 weeks
Multiple more months of Femara
IUI #1 with Femara and Follistem 75 units: BFN
IUI #2 with Follistem 150 units: BFN
Dec 2015: 1st IVF. 10 eggs retrieved with 8 eggs fertilized. 5 day transfer of two embryos with 2 frozen embies. BFN
January 2016: FET #1 2 embryos: BFN
March 2016: 2nd IVF cycle. 4 eggs retrieved with 2 fertilized. Quick two day transfer of both embryos: BFN
April/May 2016 IVF #3. 11 eggs retrieved. 10 mature. 7 fertilized. 2 5AA blasts transferred 5/11/2016 BFN
September 2016 IVF #4: 17 follicles growing, premature ovulation through Cetrotide. Retrieval cancelled.
April 2017 IVF #5: 9 follicles growing, 6 eggs retrieved with 5 fertilized. Transfer of three blasts. BFN
June 2017: IVF #6: 2 follicles growing, 5 eggs retrieved with 5 fertilized. Transfer of 5 3-day embryos. Chemical pregnancy. BFN
Nov/Dec 2017: Donor egg cycle. 33 eggs retrieved, 26 mature. 26 fertilized.
u know i might end up being cycle buddies with u ladies
Unexplained Infertility - but I am 40...Low AMH .30
7 - IUI (50mg-150mg Clomid) Feb - August 2016 all BFN
IVF#1 August 2016 (Antagonist protocol 4/5 eggs) Cancelled cycle
IVF#2 Sept 2016 (microdose luporn pro - disappearing follies, ONLY ONE, convert to IUI) BFN
IVF#3 November 2016 (4 ER, 3 F, 3DT)-BFP
IVF#4 March 2017 //EPP (10 ER (1 wonky so 9 ER) 7F, 3B (5AB, (2)5BB) PGS tested- ALL abnormal
IVF#5 April 2017 // EPP (7 ER, 7F yes! 6B) 2/5 day 4/6 day - 2 PGS normal! yes!!
IVF#6 May 2017 // Antagonist didn't have time for Estrogen Priming...(4 ER, 3 F, 3B) (5AB, (2) 5BB) 2 PGS normal, yes!!
IVF#7 June 2017 // EPP praying this is it and then on to an FET!
Multiple months of Clomid/Femara
End of March 2015: BFP with Femara! Saw heartbeat at 5.5 weeks. M/C at 11 weeks
Multiple more months of Femara
IUI #1 with Femara and Follistem 75 units: BFN
IUI #2 with Follistem 150 units: BFN
Dec 2015: 1st IVF. 10 eggs retrieved with 8 eggs fertilized. 5 day transfer of two embryos with 2 frozen embies. BFN
January 2016: FET #1 2 embryos: BFN
March 2016: 2nd IVF cycle. 4 eggs retrieved with 2 fertilized. Quick two day transfer of both embryos: BFN
April/May 2016 IVF #3. 11 eggs retrieved. 10 mature. 7 fertilized. 2 5AA blasts transferred 5/11/2016 BFN
September 2016 IVF #4: 17 follicles growing, premature ovulation through Cetrotide. Retrieval cancelled.
April 2017 IVF #5: 9 follicles growing, 6 eggs retrieved with 5 fertilized. Transfer of three blasts. BFN
June 2017: IVF #6: 2 follicles growing, 5 eggs retrieved with 5 fertilized. Transfer of 5 3-day embryos. Chemical pregnancy. BFN
Nov/Dec 2017: Donor egg cycle. 33 eggs retrieved, 26 mature. 26 fertilized.
@radmom27- you are so right about AF! Perhaps ours will come on the same day and we will true cycle buddies. No signs of her yet for me so who knows!
Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive)
March-May 2016: 1 TI and 2 IUIs- BFN
June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary.
August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN
Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN
January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze
May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline
Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid
Nov 2017- Hysterscopy to remove polyp
Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated
Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone
Apr 2018- DE FET cancelled for lining issues
Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin
Baby Born born early @ 33.5 weeks due to Pre-e
Back for # 2!
@mtpbadger-I'm sorry that your body is not cooperating. But you're not out yet, and hopefully extra days on letrozole does the trick.
AFM- started lupron injections yesterday, and have one more bcp to take tomorrow. Will have the baseline ultrasound next Monday and if all goes well, I'm going to start stimulation injections next Friday!
Unexplained infertility/AMA, polycystic ovaries, insulin resistance
FET#1(July 2017): eSET of first of 4 PGS-normal embryos, DS born 3/30/2018
FET#2(Oct/Nov 2019): eSET
Just got a voice message from my RE letting me know she will be out of the office next week and gave me the contact for the Dr's covering for her.
She believes this round will be converted to an IUI. She staffed my case with some other RE's in the practice and said if this round doesn't work, she wants to try putting me on Metformin and Ovasitol (supplement) for a month to see if my lining reacts better being on those. Even though I don't have the "standard" PCOS symptoms, other RE's in the practice have seen some improvement in lining being placed on these two things. I guess it's worth a shot!
HI Ladies!! Got my report.
I want to say I'm happy but I think right now I'm just relieved that I have something. So far I have a 5AA and 5AB that have made it to freeze. One was through icsi and the other regular. MAYBE I can get another one or two tomorrow PRAYING that it does happen. Just very worried about only having 2 for testing you know. They are super quality I'm told so trying to believe in that right now. This process is so expensive!! Doing it this way its gonna be at least 30/50k and so far have hopes of just 2 ugh....I'm beyond worried today! I know theres nothing I can do, but I do wonder if I just shouldve done the fresh cycle transfer. Some embryos do grow better inside why they do the 3dt. Last cycle I got 3 and pregnant with twins. This cycle I had 9 and so far back to 2 and hopes they're normal!
My brain is going a mile a minute, I'm tempted next cycle to try and do a fresh transfer and then hopefully test whatever else makes it. I know it sounds crazy but if others dont come through tomorrow then I just wonder if my lil embabies are happier being in me then out of me....
Unexplained Infertility - but I am 40...Low AMH .30
7 - IUI (50mg-150mg Clomid) Feb - August 2016 all BFN
IVF#1 August 2016 (Antagonist protocol 4/5 eggs) Cancelled cycle
IVF#2 Sept 2016 (microdose luporn pro - disappearing follies, ONLY ONE, convert to IUI) BFN
IVF#3 November 2016 (4 ER, 3 F, 3DT)-BFP
IVF#4 March 2017 //EPP (10 ER (1 wonky so 9 ER) 7F, 3B (5AB, (2)5BB) PGS tested- ALL abnormal
IVF#5 April 2017 // EPP (7 ER, 7F yes! 6B) 2/5 day 4/6 day - 2 PGS normal! yes!!
IVF#6 May 2017 // Antagonist didn't have time for Estrogen Priming...(4 ER, 3 F, 3B) (5AB, (2) 5BB) 2 PGS normal, yes!!
IVF#7 June 2017 // EPP praying this is it and then on to an FET!
Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive)
March-May 2016: 1 TI and 2 IUIs- BFN
June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary.
August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN
Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN
January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze
May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline
Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid
Nov 2017- Hysterscopy to remove polyp
Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated
Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone
Apr 2018- DE FET cancelled for lining issues
Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin
Baby Born born early @ 33.5 weeks due to Pre-e
Back for # 2!
I go back on Wed for us/bw. I actually got an email from my nurse saying to order the ovasitol right away and I'll have to get some labs drawn before starting the metformin.
@hopeful_mom fingers crossed that the other two make it to freeze tomorrow! If it makes you feel any better, I had several day 6s make it and even a day 7, So they still have a chance!!
@hopeful_mom- congrats on two beautiful embies and hope you get two more tomorrow. I've read some papers out there, and assuming that the culture technique is fine, the eggs that don't make the cut by day 5 are usually due to aneuploidy (chromosomal problems). So while it may be disappointing that there aren't as many day 5 embryos left, at least you know that the ones that made it have a higher chance of it being normal! But at the same time, I do understand your desire to do a day 3 transfer. I've started this IVF journey with embryo banking in mind (target: 5-6 PGS normal embryos), but after two cycles and 0 PGS normal embryos, I'm tempted to transfer just whatever I can get and hope for the best... But for me, my odds of getting a chromosomally-normal embryo is so low that I have to test anyway. Sigh.
Unexplained infertility/AMA, polycystic ovaries, insulin resistance
FET#1(July 2017): eSET of first of 4 PGS-normal embryos, DS born 3/30/2018
FET#2(Oct/Nov 2019): eSET
@cashewchicken thanks for the info! I think its the fact that i did get pregnant with 2 out of the 3 that I'm starting to lose hope in this prolonged process. I wouldve gambles without the test as they say the good ones are the ones that are suppose to stick. Its my OH my MC was terrible and lost so much blood...it was a horrible ordeal that he can't see me go through it again. Not that i want too but nothing is 100%. Thats whats freaking me out too is reading about people that MC where the baby stops growing and its PGS normal. How is that even possible? Its such a miracle and it amazes me how it just happens so easily for others. I'm all OOP and yes you want this so bad but where do u draw the line. Down payment for a house...I hate to look at the expense but knowing 40k was all for nothing and ur at it again is hard when all those bills start coming in...Hoping I'll get some good news tomorrow! how many of your made it to day 5? Its very scary but still works for many. Your body is suppose to be able to tell which are the healthy embryos and keep them. I understand ur struggle, why we're all here...but I still have my angry days! I think i was overly excited to finally have a better response but in the end is looking to be the same outcome is my concern too.
Unexplained Infertility - but I am 40...Low AMH .30
7 - IUI (50mg-150mg Clomid) Feb - August 2016 all BFN
IVF#1 August 2016 (Antagonist protocol 4/5 eggs) Cancelled cycle
IVF#2 Sept 2016 (microdose luporn pro - disappearing follies, ONLY ONE, convert to IUI) BFN
IVF#3 November 2016 (4 ER, 3 F, 3DT)-BFP
IVF#4 March 2017 //EPP (10 ER (1 wonky so 9 ER) 7F, 3B (5AB, (2)5BB) PGS tested- ALL abnormal
IVF#5 April 2017 // EPP (7 ER, 7F yes! 6B) 2/5 day 4/6 day - 2 PGS normal! yes!!
IVF#6 May 2017 // Antagonist didn't have time for Estrogen Priming...(4 ER, 3 F, 3B) (5AB, (2) 5BB) 2 PGS normal, yes!!
IVF#7 June 2017 // EPP praying this is it and then on to an FET!
AFM: I went in for BW to see if my levels were ready to start estrogen priming but as I assumed they are not. I was glad I went in so I could find a nurse to help get me answers on my frosties! So one more frostie is joining the party yay!!
So I have one 5AB (reg fert) and two 5BB (icsi) I know I should be happy with 3, I'll be even happier when they all come back pgs normal
Praying this next cycle can be as successful or maybe a lil more
Unexplained Infertility - but I am 40...Low AMH .30
7 - IUI (50mg-150mg Clomid) Feb - August 2016 all BFN
IVF#1 August 2016 (Antagonist protocol 4/5 eggs) Cancelled cycle
IVF#2 Sept 2016 (microdose luporn pro - disappearing follies, ONLY ONE, convert to IUI) BFN
IVF#3 November 2016 (4 ER, 3 F, 3DT)-BFP
IVF#4 March 2017 //EPP (10 ER (1 wonky so 9 ER) 7F, 3B (5AB, (2)5BB) PGS tested- ALL abnormal
IVF#5 April 2017 // EPP (7 ER, 7F yes! 6B) 2/5 day 4/6 day - 2 PGS normal! yes!!
IVF#6 May 2017 // Antagonist didn't have time for Estrogen Priming...(4 ER, 3 F, 3B) (5AB, (2) 5BB) 2 PGS normal, yes!!
IVF#7 June 2017 // EPP praying this is it and then on to an FET!
As for how many of mine made it to day 5... my first cycle, a contamination killed all the embryos so I had 0. My second, 5 made it to blastocyst, biopsied and sent for testing, and all 5 came back abnormal. I'm hoping the reason they were abnormal was because many of the eggs had to be matured in vitro overnight. Apparently in vitro egg maturation results in higher % of chromosomally abnormal eggs.
Unexplained infertility/AMA, polycystic ovaries, insulin resistance
FET#1(July 2017): eSET of first of 4 PGS-normal embryos, DS born 3/30/2018
FET#2(Oct/Nov 2019): eSET