Totally confused about PGD testing..

runner76

i am 39 years old.. i had one miscarriage a year ago.. My RE said he would suggest pgd based on that.. he also said he can control for multiples better by transferring only one embryo.. can he only do that with pgd?? So now i need to do retrieval one cycle and transfer the following cycle.. i assume that would be the next month?? For example retrieval in may and transfer june? i am hoping it wouldn't be any longer.. this waiting has me crazy and ill be 40 in august. i also read about pgd testing possibly having risks to the embryo... ?? 
i had a super panel blood test and i am a carrier of wilson disease ( a very rare treatable disorder)  if that is the only thing that came up and hubbys testing is good would this be a good predictor? Would we still need pgd?? 

2legbaby

PGD tests not only for genetic diseases but for chromosomal abnormalities, at our age (I am 38) 50% or more of our embryos are going to be chromosomally abnormal. Most chromosomal abnormalities are fatal and will end in miscarriage, some, like trisomy 21 (down's syndrome), may result in a viable birth. I understand how horrible the waiting is (believe me it is the worst part...I am currently in a wait for DE right now!), your RE is trying to avoid you having to experience another miscarriage. If you don't do testing they may put in more than 1 embryo to account for the fact that 1/2 is likely to be abnormal, however if both are normal you end up with twins. You will have egg retrieval 1 month, the embryos are tested day 5 and frozen and then transfer next month. Risks to embryo exist but not as much as with day 3 biopsies. I would make sure to question your RE about the embryologists experience with PGD testing and biopsying, making sure they have a few hundred biopsies under their belts. I really think at your age this testing is worth the money and the time. It doesn't guarantee you won't miscarry but it also increases the pregnancy rate per cycle to 70% (per my RE). Even though we will be using donor eggs (all our IVF cycles ended in chromosomally abnormal embryos) we will be doing the testing to give us the best chance as a good looking embryo under the microscope can be chromosomally abnormal. The fact you are a carrier for a genetic disease is another great reason to test!
I hope this helps!!!

Angelic789

Hello, runner. I had 2 miscarriages in a row 6 years ago. Still while undergoing the treatment our doc didn't make any tie with doing PGD during the further treatment.
I got interested in the point and found this piece of info.
"It is used to select embryos created through ivf before implantation and pregnancy. PGD can be used to select embryos that have less risk of having genetic disorder, increased chances of resulting in a successful pregnancy. Less cancer predisposition and even for sex selection.
There are 3 basic indications for PGD. 1. aneuploidy screening. 2. translocation analysis. 3. single gene disorders. On day 3 after retrieval, a single cell is removed from the embryo for analysis.
Benefits and risks.
PGD for translocations and single genes have been shown to be effective and offer couples new hope of having healthy children and preventing the painful decisions regarding pregnancy termination of affected fetuses. To determine if you're a candidate for PGD, talk with your doctor. Ask him about potential risks assosiated with this technique. Not all disorders can be detected with PGD, and not all clinics utilize PGD resources."
Good luck x