Infertility

DHEA and CoQ10

Hi! I've been taking these supplements suggested by my doc since Sept 15. I'm curious if anyone has any experience with these helping with egg quality and/or side effects. I've recently been having night sweats, increased appetite and muscle aches. No idea if these are connected. I'm doing 75mg DHEA and 400 mg CoQ10. Thanks
Me & DH - 41, DH has a cyst blocking his tubes, I'm just old.
IVF #1 scheduled May 2016 - 375/525 follistim, 75 menopur - cancelled cycle Day 6
IVF #2 scheduled July 2016 - new protocol, switcharoo...IUI June 2016 - BFN
IVF#3 scheduled August 2016 - estrogen & testosterone primed for 3 wks - ganirelix 7 days leading up to stim - 500 follistim, 75 menopur, 150 clomid , no follicle growth on day 6, stopped injectibles. Scanned day 9 just to check, some growth, 3 days 200 mg clomid, day 12 more growth, 100 follistim, 75 menopur, start ganirelix on day 13, ER = 0 eggs, ovulated to soon ( :( )
IVF#4 scheduled Sept 2016 - Microdose Flare protocol, cancelled stim day 6 converted to IUI (one dominant follicle)  :(  IUI cancelled ovulated too soon again. Taking a mental health break.
IVF#5 December 2016 - New protocol, same results. My adventure is over.


Re: DHEA and CoQ10

  • The DHEA is a hormone and some of the signs you described could be related, I took that same dose of CoQ10 and no side effects- make sure to mention to your doc....it was recommended since I have PCOS not to take DHEA as some women with PCOS are already making too much (not sure what your underlying fertility issues are...but I made the mistake based on internet reading and egg quality books to start the DHEA and both my acupuncturist and RE were like NO!!!!)
    ******TW*****
    Me 39 DH44
    Married 8/2/14
    TTC 9/14
    Dx: PCOS, blocked L fallopian tube, suspect poor egg quality
    MFI (low #, poor morphology)
    IVF #1 9/15 Failed
    IVF #2 12/15 Failed
    1st DE FET  5/16-BFN :(
    2nd DE FET 7/18-BFP :)
    8/17 Baby HR 140/min EDD 4/6/17
  • I guess I should have explained my situation, I go for my first official IVF consult next Tuesday. I'm 40 and all my levels (and honestly I should know, but don't) are 'low' so the supplements were to make sure the eggs we get are strong.  DH has a blockage and produces very little hence the IVF. 
    Good advice to make my doc aware of what may or may not be side effects. Thanks!
    Me & DH - 41, DH has a cyst blocking his tubes, I'm just old.
    IVF #1 scheduled May 2016 - 375/525 follistim, 75 menopur - cancelled cycle Day 6
    IVF #2 scheduled July 2016 - new protocol, switcharoo...IUI June 2016 - BFN
    IVF#3 scheduled August 2016 - estrogen & testosterone primed for 3 wks - ganirelix 7 days leading up to stim - 500 follistim, 75 menopur, 150 clomid , no follicle growth on day 6, stopped injectibles. Scanned day 9 just to check, some growth, 3 days 200 mg clomid, day 12 more growth, 100 follistim, 75 menopur, start ganirelix on day 13, ER = 0 eggs, ovulated to soon ( :( )
    IVF#4 scheduled Sept 2016 - Microdose Flare protocol, cancelled stim day 6 converted to IUI (one dominant follicle)  :(  IUI cancelled ovulated too soon again. Taking a mental health break.
    IVF#5 December 2016 - New protocol, same results. My adventure is over.


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  • I was told the same about not taking DHEA because I have PCOS. I do take CoQ10 and I don't have any side effects either.
  • I was taking CoQ10 as recommened from OB and my own research to possibly help...however once I started working with an RE after a year of TTC my blood tests came back the same so there was nothing it did to improve quality. Many supplements will possibly help but theres no evidence to suggest it does actually improve egg quality in every situation...this is what my RE told me so he said theres no magic pill to improve your eggs, but I can keep taking the supplement but its more for my "piece of mind" that I'm doing all I can...I remember feeling bloated but no other side effects. I've stopped the supplement all together I don't want tons of meds going through my body if they aren't nessessary. 
    Me 28 DH 33 | DX: DOR | HSG: Normal | IUI#1: (Clomid/HCG/Progesterone) BFN | IUI#2: (Clomid/HCG/Progesterone) BFN | IUI#3: (Clomid/HCG/Progesterone) BFN | IUI#4: (Menopur/HCG/Progesterone) BFN | IUI#5: (Menopur/Gonal-F/HCG/Progesterone) BETA 7/2
  • My RE recommended both of these supplements bc I had low amh. I only got 2 eggs at my retrieval and both fertilized beautifully. I would like to think the supplements helped.
  • Thanks everyone for the info, I see RE tomorrow and will ask about side effects, etc. I really hope its working :)
    Me & DH - 41, DH has a cyst blocking his tubes, I'm just old.
    IVF #1 scheduled May 2016 - 375/525 follistim, 75 menopur - cancelled cycle Day 6
    IVF #2 scheduled July 2016 - new protocol, switcharoo...IUI June 2016 - BFN
    IVF#3 scheduled August 2016 - estrogen & testosterone primed for 3 wks - ganirelix 7 days leading up to stim - 500 follistim, 75 menopur, 150 clomid , no follicle growth on day 6, stopped injectibles. Scanned day 9 just to check, some growth, 3 days 200 mg clomid, day 12 more growth, 100 follistim, 75 menopur, start ganirelix on day 13, ER = 0 eggs, ovulated to soon ( :( )
    IVF#4 scheduled Sept 2016 - Microdose Flare protocol, cancelled stim day 6 converted to IUI (one dominant follicle)  :(  IUI cancelled ovulated too soon again. Taking a mental health break.
    IVF#5 December 2016 - New protocol, same results. My adventure is over.


  • oxinfreeoxinfree member
    edited February 2016
    my AMH was fine but my doc still recommended a different supplement when I asked about CoQ10 and DHEA. This is what he said:

    "If possible, I recommend you start to take this supplement immediately as data suggest it is beneficial for oocyte (egg) health and stability.

    Take one pill per day with food: 

    https://www.revgenetics.com/store/p-32-nitro250-micronized-resveratrol-up-to-10x-better.aspx "

    No idea if it works at all (cycling in March) but no side effects that I can see. Just thought I'd share that I'm on something different than you all for egg quality. 

    edited to correct "drug" to "supplement"
    ---
    Started TTC April 2011
    Me: 32, DH: 32
    Diagnosis: Endometriosis

    • 2012 - 3 Rounds clomid - all BFN
    • 2013 - 1 Fresh IVF with 2 day 3 embryos - BFN
    • 2014 - 1 Frozen IVF with 2 day 5 embryos - BFN
    • Took a long break, continuing trying naturally
    • Feb 2016 - Biopsy = Endo, DH sperm improved from 1% to 6% morphology
    • March 2016 - Fresh IVF cycle with acupuncture & intralipids: 20 eggs retrieved (17 mature), 7 ICSI'd fertilized, 9 naturally fertilized. 16 total embryos!
    • April 8th - 2 embryos (1ICSI and 1 Natural) transferred. (7 blastocysts frozen), April 18th - Beta = BFN
    • Sept 23rd - Lupron Depot Injection for Endo control
    • Nov 15th 2016 - Started daily Lupron Injections for upcoming FET
    • Nov 22 - Baseline US/BW - Intralipid Infusion - Start Meds for FET with immune protocol
    • Dec 16th FET transfer of 3 embryos (1 - AA, 2 - BB)
    • TW below
    • Dec 22nd - first ever bfp (very faint lines FRER & cheapie)
    • Dec 27th Beta = 192, Dec 29th Beta = 379
    • EDD - Sept 5th 2017

    - - -
    I'm a YouTube vlogger who talks about Infertility, IVF and Endometriosis. Check it out here!
    Follow along at http://liv4today.blog
    Instagram @liv4todayvlog 


  • Saw my RE today and she was very keen on me continuing both and starting a low dose aspirin. I think we've decided to start drugs at the end of April for a May retrieval. Yikes, now it's real.
    Me & DH - 41, DH has a cyst blocking his tubes, I'm just old.
    IVF #1 scheduled May 2016 - 375/525 follistim, 75 menopur - cancelled cycle Day 6
    IVF #2 scheduled July 2016 - new protocol, switcharoo...IUI June 2016 - BFN
    IVF#3 scheduled August 2016 - estrogen & testosterone primed for 3 wks - ganirelix 7 days leading up to stim - 500 follistim, 75 menopur, 150 clomid , no follicle growth on day 6, stopped injectibles. Scanned day 9 just to check, some growth, 3 days 200 mg clomid, day 12 more growth, 100 follistim, 75 menopur, start ganirelix on day 13, ER = 0 eggs, ovulated to soon ( :( )
    IVF#4 scheduled Sept 2016 - Microdose Flare protocol, cancelled stim day 6 converted to IUI (one dominant follicle)  :(  IUI cancelled ovulated too soon again. Taking a mental health break.
    IVF#5 December 2016 - New protocol, same results. My adventure is over.


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