Trouble TTC

Newbie

Hi everyone, 
I have been a follower of this board for a while now, and it has been so helpful during those tough TTC moments. I am 26 and my DH is 30. We have only been married for 9 months, but have been ttc since day one. I have always assumed it would take a while for me to get pregnant as I was dx with PCOS when I was 14. I have very "typical" PCOS symptoms: overweight, acne, irregular (extremely heavy/nonexistent) periods, hirsutism, etc. Since my dx in 2003, I have been on and off birth control to regulate my cycles and keep the acne manageable. 

DH and I agreed early on in our engagement that we would start ttc immediately after our wedding knowing it could take a while. We tried on our own for 6 months before seeking out a reproductive specialist. He immediately ran tons of blood work and put me on 1000mg of Metformin, which made me feel incredibly ill. I stuck it out though and the side effects got much more bearable and now I hardly notice any symptoms despite an increase in my dose to 1700mg. My blood work showed an extremely high AMH and a very off balance LH/FSH ratio. DH had an SA and everything was completely, if not better than, normal. So off we went to focus on my uncooperative ovaries...

In August I began my first round of Clomid 100mg days 3-7. After a very disappointing ultrasound (with no follicles bigger than 10mm), he put me on a step-up dose for the following five days of 150mg. That did the trick and I had a 20 mm follicle on CD21 (better late than never). I then did a trigger shot to induce ovulation, BD, and began the TWW. BFN :( 

In September, the Dr decided to try Femara to see if I could have some more viable follicles than I produced on Clomid. Lets just say, after the original dose and a step-up dose, femara was a bust for me. So I began two weeks of birth control to induce a period.

So, here we are in October. Back to Clomid 150mg plus Dexamethasone. I will begin this protocol in two days. Fingers tightly crossed that this will work :)

I have also been going to acupuncture and taking prenatal vitamins, CoQ10, Alpha Lipoic acid and NAC to try to improve my egg quality.

Whew, sorry for the length! I am so happy to finally be a member of this board and really look forward to talking with everyone :)
Me: 26
DH: 30
Married January 10, 2015
TTC #1: February 2015
PCOS DX: 2003

Re: Newbie

  • Welcome! Hopefully this next round will work for you!
    Married to DH 10/6/12
    TTC since 5/14
    Unexplained with (controlled) hypothyroidism and suspected ovulatory dysfunction (but, I do ovulate on my own)
    Clomid 50 mg 3/15 (unmonitored) - BFN
    Clomid 50 mg + metformin 4/15 (unmonitored) - BFN 
    First RE appt. 5/15; Natural cycle 5/15 monitored with 2 mature follicles and Pregnyl Trigger (full dose) + prometrium - BFN
    6/15 HSG - clear tubes & normal uterus; great PCT test results
    TI - 100 mg Clomid + prometrium (AM & PM) + vaginal estrace (AM & PM) 6-7/15 (monitored) --> no additional response and thinned lining - BFN
    TI - Injectables (follistim + Gonal-F, Ganirelix, & 1/2 dose Pregnyl) + prometrium (AM & PM) 9/15 --> 3-7 mature follicles (3 definites and 4+ that could have matured due to trigger) @ O -->BFN + 5 large cysts
    BC for 2 weeks due to cysts
    TI - Injectables (Gonal-F, Ganirelix & full dose Pregnyl) + prometrium (AM & PM) 10/15 --> 1 mature follicle --> BFN 
    TI - Last attempt at injectables (Gonal-F, Ganirelix & 1/2 dose Pregnyl) + crinone (AM only) + vaginal estrace (AM & PM) 11/15 --> 3-4 mature follicles --> BFP!! 11/27/15 @ 13dpo (shockingly, actually waited until then to test)

    Beta #1 @ 16dpo (11/30/15) = 1,075
    Beta #2 @ 19dpo (12/3/15) = 3,150
    One baby: Saw heartbeat @ 5w5d (114 bpm; baby measuring 2.3mm)

    "Great Things are Happening"
  • Welcome and good luck on your next cycle
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  • Welcome and good luck!!
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