Trouble TTC

IUI - what to ask/what are my options?

My 4th round of clomid has just proven to be a bust, so I think we will be moving on to IUI. I was wondering if I could get some advice from those who have gone through IUI already about what questions I should be asking at our upcoming appointment when we discuss our next steps - e.g. what type of monitoring to ask for, risks to be concerned about, etc. Also, I know different people take different routes, but what is the "typical" number of times to try IUI before moving on to IVF?
Thanks for any info!

P.S. I don't have a signature but my situation is probable PCOS, everything else looks ok as far as we know

Re: IUI - what to ask/what are my options?

  • GoldenKeysGoldenKeys admin
    edited September 2015
    Are you seeing an RE or an OBGYN?   Have you done all of your testing (including an SA for your husband), and are you being monitored?   I'm asking because IUI will not significantly raise your chances of success if everything else is ok.   If you haven't been monitored or completely tested, my advice would be to STOP taking the Clomid immediately until you are.   You might have thinned your lining too much (a common side effect of Clomid) which would make implantation impossible, and I've seen this happen many times.

    There isn't a 'typical' number of IUI's before IVF because it's more dependent on your diagnosis and other factors.   IUI's are very low risk and the monitoring is to see your response to the fertility meds, not for  the IUI procedure.....   good luck! 

      


    Married for 7 years, TTC for 4 years
    dx:  Diminished Ovarian Reserve
    2 Clomid IUI's + 4 injectable IUI's= 5 BFNs and 1 mc




  • riveridgionalriveridgional member
    edited September 2015
    I agree with @GoldenKeys. Relevant factors would be your DH's sperm analysis and the results of any postcoital test (PCT). In case you don't know, the PCT will show if your environment is "welcoming" to the sperm and if there are enough the morning after sex. Clomid can decrease your postcoital results because a side effect is reduced CM. This test (and SA if your PCT is not 10/10) and ultrasounds are important in determining whether an IUI is preferable. For example, our PCT came back great, so there is no measurable increase in my chances with IUI over TI.

    Also, to encourage you to seek monitoring on Clomid if you haven't already, I took 2 rounds of Clomid unmonitored with my OB. Had I been monitored, I would have found out much sooner that I actually don't respond any better to it, and it thinned my lining, reducing my chances of pregnancy signficantly. Had I seen my RE before doing Clomid, I would have only wasted 1 cycle instead of 3. With my RE, I did CD3 bloodwork and ultrasound to get my baseline levels and to ensure no cysts were present. I then went back 2 or 3 more times befote ovulation for additional bloodwork and/or ultrasounds.
    Married to DH 10/6/12
    TTC since 5/14
    Unexplained with (controlled) hypothyroidism and suspected ovulatory dysfunction (but, I do ovulate on my own)
    Clomid 50 mg 3/15 (unmonitored) - BFN
    Clomid 50 mg + metformin 4/15 (unmonitored) - BFN 
    First RE appt. 5/15; Natural cycle 5/15 monitored with 2 mature follicles and Pregnyl Trigger (full dose) + prometrium - BFN
    6/15 HSG - clear tubes & normal uterus; great PCT test results
    TI - 100 mg Clomid + prometrium (AM & PM) + vaginal estrace (AM & PM) 6-7/15 (monitored) --> no additional response and thinned lining - BFN
    TI - Injectables (follistim + Gonal-F, Ganirelix, & 1/2 dose Pregnyl) + prometrium (AM & PM) 9/15 --> 3-7 mature follicles (3 definites and 4+ that could have matured due to trigger) @ O -->BFN + 5 large cysts
    BC for 2 weeks due to cysts
    TI - Injectables (Gonal-F, Ganirelix & full dose Pregnyl) + prometrium (AM & PM) 10/15 --> 1 mature follicle --> BFN 
    TI - Last attempt at injectables (Gonal-F, Ganirelix & 1/2 dose Pregnyl) + crinone (AM only) + vaginal estrace (AM & PM) 11/15 --> 3-4 mature follicles --> BFP!! 11/27/15 @ 13dpo (shockingly, actually waited until then to test)

    Beta #1 @ 16dpo (11/30/15) = 1,075
    Beta #2 @ 19dpo (12/3/15) = 3,150
    One baby: Saw heartbeat @ 5w5d (114 bpm; baby measuring 2.3mm)

    "Great Things are Happening"
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  • When you say unmonitored @riveridgional do you mean ultrasound, bloodwork, or both?  I have had 4 rounds of Clomid with bloodwork only.  We have been seeing OBGYN for this and have an appt to see RE at the end of March (earliest appt we could get).  We are in the TWW of this 4th cycle right now, and we were going to do another if this cycle was a BFN again in the meantime, but not sure what to do now. TIA

    Me 36, DH 35

    TTC since 8/2014

    Clomid started Oct 2015

    4 Clomid Cycles all with BFN

    First appt with RE diagnosed with PCOS and Uterine Polyp

    RE started Metformin

    Polypectomy  May 13, 2016

    <a href="http://www.fertilityfriend.com/home/52baf6" style="font-size:smaller;" >
    < img src="http://www.fertilityfriend.com/home/52baf6/thumb.png" />
    < br /> My Ovulation Chart</a> || <a href="http://www.fertilityfriend.com" style="font-size:smaller;" >Ovulation Tracker</a>
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