October 2015 Moms
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Zofran vs Diclegis

mamasnowwhitemamasnowwhite member
edited March 2015 in October 2015 Moms
doc prescribed me both. Zofran I'm sure most know is most commonly prescribed, Diclegis is less common I think, but the only category A (safest for preg) med for nausea.

I have friends who have safely and successfully taken zofran during pregnancy with no issues with baby. but my lovely coworkers (*sarcasm*) started freaking me out sending me tons of articles about zofran lawsuits, birth defects etc (they're the worst. I'm constantly telling them to stop this). So I've decided not to take it.

The purpose of this post however is to gush about how WONDERFUL Diclegis is!! Doc told me it's unisom + vitamin B6, and that if the pharmacy can't fill it that you can take that combo and it will essentially be the same. I'm sure it's more cost effective as well bc my prescription was $30 for 1 month w/insurance :-\ anyways, not only did it help me sleep (I have been having terrible restless sleep/insomnia) but woke up for the first time with absolutely no nausea! Previously I had been vomiting every single morning, and if I waited too long to eat breakfast it would get soooo bad. Today I didn't eat until noon and I didn't have one bit of nausea from my empty stomach! Hurray! Hopefully this will also help my eating habits bc I have been eating way more than usual due to empty stomach causing horrible nausea.

For the first time this pregnancy (10 weeks) I actually feel AMAZING! Hope this post helps someone else :)

*Edited to correct a typo :)

Re: Zofran vs Diclegis

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    Thanks for recommending diclegis, I'm gonna ask my doctor about it. Did your doctor ever recommend Reglan? That's the one I'm taking now but it's only helping me vomit less, I still have all the other "fun" symptoms. Anyways glad to hear you're doing better!! Can't wait to be join the nausea-free club! ;)
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    I'm a huge advocate for Diclegis as well. Completely helped my constant nausea. So glad you're feeling better too!
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    rue:Drue:D member
    I've been on the Diclegis for a couple of days and I don't feel 100% better, but definitely better than I have been. I tried just Unisom and B6 and it didn't seem to work for me - I actually felt worse the day after.
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    Thanks for sharing @mamasnowwhite! I will email my dr about it.
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    Just a side note--you can make your own combo of Unisom & B6 but it may make you sleepier than diclegis. Diclegis is formulated to be more of an extended release so the unisom doesn't hit you as hard. Just thought I'd add that since I know most of us are probably struggling with exhaustion already :)
    DH & I married 12/17/2012
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    DH (41)-no MFI
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    08/2014-Femara 5mg + trigger + IUI + 2nd trigger= BFN
    09/2014-Clomid 100mg + trigger + IUI + 2nd trigger= BFN
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    12/2014-Femara 5mg + stair step with additional 5 days Femara 5mg + trigger + IUI=BFN
    01/2015-Femara 5mg + Gonal F 25 units + trigger (plus additional Gonal F 100 units on trigger night) + IUI= BFP!!! Twins due 10/2015
    09/28/2015- Surprise!  Conrad and Hudson born at 35w6d!  
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    how many pills are you guys taking a day?  I started with 2 every night before bed but something by the following afternoon my nausea returns.  My doctor said you can add one pill in the morning and one in the afternoon.  Its just such an expensive medicine I was trying to do with less!
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    Declegis is also called diclectin in Canada. Its the ONLY drug class A . Its helped me quite a bit. Glad you are finding it helpful too.
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    I love it!
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    blsav23 said:

    Just a side note--you can make your own combo of Unisom & B6 but it may make you sleepier than diclegis. Diclegis is formulated to be more of an extended release so the unisom doesn't hit you as hard. Just thought I'd add that since I know most of us are probably struggling with exhaustion already :)

    ^^^ YES about the extended release, forgot to mention that!
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    anbailey3 said:

    how many pills are you guys taking a day?  I started with 2 every night before bed but something by the following afternoon my nausea returns.  My doctor said you can add one pill in the morning and one in the afternoon.  Its just such an expensive medicine I was trying to do with less!

    My prescription is for 1 at night before bed :)
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    @nanipepi doc didn't mention reglan at all, but it may be bc I came in asking for zofran and she said she'd give me zofran but recommended I try Diclegis first
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    anbailey3 said:

    how many pills are you guys taking a day?  I started with 2 every night before bed but something by the following afternoon my nausea returns.  My doctor said you can add one pill in the morning and one in the afternoon.  Its just such an expensive medicine I was trying to do with less!

    I'm taking the over the counter combination, but when I had the free sample of Diclegis, I took two at night before bed. You can also take 1 or 2 during the day as needed, but I found that 2 at night made it tolerable for me.
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