Pregnant after IF

Luvboston and runcc

I was hoping you could help me with a few lovenox questions. You both gave me some advice a few weeks ago but I was looking for more advice. I was put on in by my RE who vacillated whether or not whether to use it, as I have no clotting disorders that were ever found (the Doppler u/s I had done at c.crm showed a very slight decreased blood flow to right uterine artery but I don't think my RE even knew that info). She basically just said it 'could' increase blood flow to the uterus/baby in people with recurrent loss or unexplained infertility. I then saw my OB who doesn't like me using it at all and referred me to the MFM clinic for evaluation. Now, DH has done some 'research ' and found that it can cause many side effects such as hemorrhaging in the fetus and a link between lovenox and autism. When you guys saw MFM or Dr. Kk, were the risks discussed? Did you hear of these kinds of problems? DH has me very worried now and wants me to stop ASAP (which I won't obviously until I see MFM). Just looking for advice and/or reassurance. Tia!
Me: 37, DH: 38: ttc 7 years, dx: unknown
10/11: after 2 years, saw a RE, FSH 5.4
11/11: BFP! (surprise after thyroid & normal hsg),
12/11: missed m/c after 7 week u/s, 1/12: D&C
6/12 IUI#1-IUI #3: clomid = BFP!, C/P
IVF #1(10/12) FSH 5.4, AFC: 16 long Lupron, 5R/5M/4F, all 4 made it to 5dt, 1 blast/1-8 cell transferred=BFN
IVF #2(12/12)AFC 21, MD lupron, 4R/4M/3F, 5dt of 1 blast and 2-8cell. BFN.
IVF#3(4/13) Natural start antagon protocol, 12R,11F. one PGS normal at day 6 transfer. BFN.
IVF#4 (11/13) C.CRM (ODW.U normal 8/13 Still no Diagnosis) EPP/antagonist. ER 13R/7M/6F. Only 1 made it to freeze. Abnormal. Looking into options of DE, Fresh vs frozen.
10/14 new local RE to look into what's next. CD3 FSH 4.7, AMH 0.9. Met with DE agencies and exploring options for feb/march 2015.
Surprise natural bfp (4 days before donor is signed). Beta #1 at 9dpo: 51.8, 2nd beta: 195 (25 hours doubling) @11dpo. 3rd beta (12/15): 516 (35 hrs doubling) 4th beta(12/17): 895 (58 hours doubling) 5th beta(12/19): 2120. U/S at 5w0d(12/22): one gestational sac with yolk sac. U/S #2 (6w0d)12/29. One little bean measuring 6w0d with HR 124. 3rd u/s(1/4)7w0d: baby measuring 7w2d. HR 134. 3/30: A/S at MFM went great except for low lying placenta. Verifi results are normal! Team Blue! Please send any positive thoughts our way! EDD:8/24/2015
Baby Will born 8/18. He's perfect.

Re: Luvboston and runcc

  • Huge hugs! This is so hard. Chiming in since I am also in lovenox. I know Dr. KK, my nurse there, my MFM and OB never once mentioned the side effects. I have quite a few clotting issues and have been out of work all 3rd tri for fear of clotting. I am on Lovenox 2x a day and scans weekly for clots/ issues with baby. I also was on prometrium and prednisone for a really long time and the side effects of that are bad too. I never heard of the autism link but the rates are much higher in NJ and especially for a boy- so I'm not sure what to think about that. I know that with the lovenox you can't have an epidural- and I will be switching to heparin in a few weeks (at 36 weeks). I would also love to hear what the other ladies say.
    ***WARNING***

    TTC Since 12/2008;  DH: 32, Azoospermia     me: 33, DX during IVF #4: Low AMH (Normal FSH) / SER due 
    to IVF Meds (causing failure to fertilize) Recent DX: Hashimoto's, Lupus Anticoagulant, White Blood Cell Disorder 
    High ANA, ATA, & APA, PAI-1 Heterozygous= blood clotting disorder; connective tissue disorder 
    IVF w/ ICSI #1 2/2011     IVF w/ ICSI #2 5/2011    IVF w/ ICSI #3 12/2012   *New RE* IVF w/ ICSI #4  5/2013
    IVF w/ ICSI #5 8/2013 (Natural Cycle- No drugs)- One follicle->one blast. CCS normal. FET 9/10- 6BB blast. m/c @ 5w
    IUI #1 12/23- BFN  IUI #2 Cancelled (ovulated during AF)  Prep:CoQ10 (300 mg); DHEA (25 mg); Melatonin (3 mg), Folgard 2.2, Metformin 500 2x, Levothyroxine 50mcg, Aspirin 81mg w/ calcium, B12,  Vit. D 4000 & Prenate Elite Daily; Cabergoline 1/2 pill 2x week-  Cycling: Estrace Priming; Prednisone 10mg, Lovenox 40mg 2x,  Femera & Menopur   
    IUI #2.1 6/30 & 7/1. 1st Beta: 90 (7/15); 2nd Beta: 226 (7/17); 3rd Beta: 766   EDD: 3/23/2015

       **ALL WELCOME**                                    My Blog 
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  • luvbostonluvboston member
    edited February 2015
    I never heard of the autism thing. And I don't know what you mean by hemoraging in the fetus. What can happen is that if you get an SCH the blood thinners can make it bigger and then cause a problem for the fetus. Of all the doctors I've seen the only thing they were ever concerned about was if I were in a car accident that it's not reversible. And that I personally get huge hematomas on my stomach but I switched to arixtra which is in the same family and it causes less cause its 1x a day.

    However I've fallen been in car accidents cut myself and done every other stupid thing and never had a problem. I think fear of the unknown is a major factor with OBs. My regular OB has never had a problem with it she was more concerned about prednisone.
    6 m/c
    Anovulatory cycles, increased Synthroid Diagnosed Sep 2010
    Natural cycle Dec 2010 BFP M/C 6 1/2 Weeks, D&E Jan 2011
    1 Clomid/Ovidrel BFN May 2011
    Natural cycle Aug 2011 BFP M/C 4 Weeks
    1 IUI Sept 2011 BFP M/c 7 weeks
    Provera Dec 2011 BFP M/C 3 Weeks
    DQ ALPHA HLA MATCH, High NK Cells Diagnosed Dec 2011
    IVF March 2012 BFP m/c 4weeks 5 days (IL, Prednisone)
    IVF#2w/DS July 2012 MEGA FAILURE BFN (IL, Dexamethasone)
    Diagnosed No real HLA Match, DQ Beta Triad, High TNF, Low NK Cells
    Oct 2012 Natural Cycle m/c 4wks (Lovenox, Prednisone) 
    Went to Beer Center- high tnf, low lad, implantation failure
    Nov/Dec 2012 LIT Treatment
    Dec 12 Humira
    Jan 2013 BFP
    Humira,LIT,Prednisone, Lovenox, IVIG, Baby Aspirin
    Miracle Born August 2013 Premature

    Yours doesn't have to be a sad story



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    Lilypie - (ugiy)


  • luvboston said:
    I never heard of the autism thing. And I don't know what you mean by hemoraging in the fetus. What can happen is that if you get an SCH the blood thinners can make it bigger and then cause a problem for the fetus. Of all the doctors I've seen the only thing they were ever concerned about was if I were in a car accident that it's not reversible. And that I personally get huge hematomas on my stomach but I switched to arixtra which is in the same family and it causes less cause its 1x a day. However I've fallen been in car accidents cut myself and done every other stupid thing and never had a problem. I think fear of the unknown is a major factor with OBs. My regular OB has never had a problem with it she was more concerned about prednisone.

    Thanks! I don't know what DH meant about the hemorrhaging either really, some article he read but I didn't actually see. I appreciate the reassurance and the sharing of your personal experience.
    Me: 37, DH: 38: ttc 7 years, dx: unknown
    10/11: after 2 years, saw a RE, FSH 5.4
    11/11: BFP! (surprise after thyroid & normal hsg),
    12/11: missed m/c after 7 week u/s, 1/12: D&C
    6/12 IUI#1-IUI #3: clomid = BFP!, C/P
    IVF #1(10/12) FSH 5.4, AFC: 16 long Lupron, 5R/5M/4F, all 4 made it to 5dt, 1 blast/1-8 cell transferred=BFN
    IVF #2(12/12)AFC 21, MD lupron, 4R/4M/3F, 5dt of 1 blast and 2-8cell. BFN.
    IVF#3(4/13) Natural start antagon protocol, 12R,11F. one PGS normal at day 6 transfer. BFN.
    IVF#4 (11/13) C.CRM (ODW.U normal 8/13 Still no Diagnosis) EPP/antagonist. ER 13R/7M/6F. Only 1 made it to freeze. Abnormal. Looking into options of DE, Fresh vs frozen.
    10/14 new local RE to look into what's next. CD3 FSH 4.7, AMH 0.9. Met with DE agencies and exploring options for feb/march 2015.
    Surprise natural bfp (4 days before donor is signed). Beta #1 at 9dpo: 51.8, 2nd beta: 195 (25 hours doubling) @11dpo. 3rd beta (12/15): 516 (35 hrs doubling) 4th beta(12/17): 895 (58 hours doubling) 5th beta(12/19): 2120. U/S at 5w0d(12/22): one gestational sac with yolk sac. U/S #2 (6w0d)12/29. One little bean measuring 6w0d with HR 124. 3rd u/s(1/4)7w0d: baby measuring 7w2d. HR 134. 3/30: A/S at MFM went great except for low lying placenta. Verifi results are normal! Team Blue! Please send any positive thoughts our way! EDD:8/24/2015
    Baby Will born 8/18. He's perfect.
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