I know my ovarian reserve is low and that my egg quality is not ideal. But, USs have shown good follicles, my husband has great sperm, the progesterone tests have indicated that I am ovulating, and we have either had sex or an IUI in the right time frame. We have been TTCAL for 37 cycles.
I was thinking tonight about whether other options are actually options-- embryo adoption and donor eggs. But, what if my egg and my DH's sperm are meeting up and fertilization is taking place, but after they hook up they can't find a home. What if my uterus is just not hospitable anymore? Do you know of any tests that they can do to see if a uterus is compatible for conception?
I plan to call tomorrow and ask the RE's nurse, but I am curious if this is a possibility or of I am just grasping at straws.
TIA
Married to the Love of My Life since September 14, 2002.
Me: 39 DH: 36
BFP#1: 10/20/08, EDD: 6/29/09
PIH, bedrest for 4 wks, delivered at 39 weeks by induction and then c-section- Healthy baby boy on 6/24/09 :-)
BFP#2: 11/24/11, EDD: 8/4/12, Angel Baby- 2/19/12
Enlarged bladder seen on U/S at 12 weeks (1/15/12), possibly LUTO or Prune Belly, Heartbeat at OB on 2/17/12,
No heartbeat/movement at U/S on 2/20/12, (missed MC), D&E:2/22/12. Miscarried our sweet angel boy @ 16 wks
TTCAL since June 2012,
Progesterone normal, FSH elevated & AMH on the low side-- "ovaries acting older"
Clomid cycles: 50 mg in February, July, August, September, November 2013, June 2014-- BFNs!! :-(
August & September 2014: Clomid, HCG and IUI-- BFNs
September 2014: FSH= 15.7 AMH= 0.25 UGH!!! Old lady Ovaries!!!
October & November 2014: Gonadatropin injections, HCG & IUI... BFNs!!
I've thought about this and have done some reading on it. I think the whole concept of something going on at the molecular level of the uterine lining falls into the whole Reproductive Immunology camp. I know some Bumpies who have had uterine biopsies done to test for this sort of thing, usually under RI supervision.
But I could be wrong, or possibly tipsy (drinking wine over here).
I'm dealing with this now. My doctor thinks I might have a c-scar defect which is causing fluid to pool by my scar in a pocket called an isthmocele making my uterus a hostile environment. Going in for surgery later this morning. I had a uterine biopsy done two months ago where they pinch a bit of your lining to test for inflammation/infection. Mine came back negative but that is one test they can do. It was pretty scary to see the word "surrogate" written on my paperwork for future steps if this doesn't work. My doc said unfortunately there is a lot they can try to do to fix tubes and other issues but the uterus is not as "fixable".
IVF #1, Stimmed for 12 days, ER 8/22/14, 9 retrieved, 7M, 7F!! Freeze all due to fluid in uterus.
FET end of October 2014 cancelled due to fluid in uterus due to possible c-scar defect
Surgery scheduled 12/12/14 to fix possible isthmocele
3/26/15 transferred one 8 cell grade 4 embryo and one 6 cell grade 3 embryo = slow rising betas for 2+ weeks = ectopic MTX shot 4/29/15
Repeat c-scar surgery June 2015
2nd and last IVF cycle August 2015, stimmed for 12 days, 2 egg retrieved, both mature and both fertilized. Transferred both 8-cell embryos on Day 3, beta 9/5/15 = BFFN
Me(27)+ DH(30) Married since Sept.2007 BFP #1 DD born 6/1/2009 (no complications) TTC #2 March 2011 BFP# 2 after 4 rounds of clomid (blighted ovum)12/11 BFP# 3 w help of clomid 2/12 DS born 10/24/2012
TTC#3
Stopped preventing when DS was 6 months old (4/13), really started TTC 10/13 Started clomid July 2014, 3 failed rounds of clomid w OB (low pro on CD 21) sent to RE
HSG and blood work all good round 1: clomid and trigger shot~BFN round 2: clomid, trigger and IUI~BFN round 3: clomid, trigger and IUI +4 booster HCG~NOPE
On a break!!! Til April/May
round 4:clomid, trigger (missed IUI window) NO fricking way BFP
Re: I had a thought...
TTC #3 since June 2013
BFP #1 7/21/2013--EDD 3/30/14--D&C 9/24/13
BFP #2 1/28/14--MC 2/7/14
IUI #1 5mg Femara + trigger = BFN
IUI #2 5mg Femara + trigger = BFN
IUI #3 5mg Femara + trigger = BFN
Me(27)+ DH(30) Married since Sept.2007
BFP #1 DD born 6/1/2009 (no complications)
TTC #2 March 2011
BFP# 2 after 4 rounds of clomid (blighted ovum)12/11
BFP# 3 w help of clomid 2/12 DS born 10/24/2012
TTC#3
Stopped preventing when DS was 6 months old (4/13), really started TTC 10/13
Started clomid July 2014, 3 failed rounds of clomid w OB (low pro on CD 21) sent to RE
HSG and blood work all good
round 1: clomid and trigger shot~BFN
round 2: clomid, trigger and IUI~BFN
round 3: clomid, trigger and IUI +4 booster HCG~NOPE
On a break!!! Til April/May
round 4:clomid, trigger (missed IUI window) NO fricking way BFP