TTC after 35

Cross-Post: ICSI?

Hi, Ladies.

So my husband and I are currently making the many, many decisions that go along with our first IVF cycle, and we're just kind of stuck on a few things.

He's adamantly opposed to having ICSI done under any circumstances (he's worried about birth defects, and he's honestly not completely comfortable with IVF in the first place, so ICSI makes it seem even more "artificial" to him.)  I would prefer to have it done, but only if the eggs weren't fertilizing on their own.

If any of you have done or are doing IVF and don't mind sharing, did you/will you do ICSI?  Why or why not?

Thanks!
*****Signature/Ticker Warning******

Me: 41, DH: 45
DD, 6/15/2013
TTC #2 beginning January 2014
AMH 1.05; FSH range 7-11

July 2014: IUI #1.  Follistim + Pregnyl.  2 follicles--BFN
September 2014: IUI #2.  Follistim + Pregnyl + Ganirelix + Crinone.  4(?) follicles--BFN
October 2014: IUI #3.  More Follistim + More Ganirelix + Pregnyl + Crinone.  4 follicles--BFP!  Beta #1=10 Beta #2=33 Beta #3=97 Beta #4=158.  M/C 11/1/14
December 2014: IVF #1.  Microdose Lupron protocol.  9R, 9M, 9F.  3 5-day blasts transferred 12/15. BFFN.
April 2015: IVF #2.  Microdose Lupron protocol.  16R, 15M, 12F. Transferred 2 5-day blasts 4/12 and froze 4--BFP!  M/C 5/25/15
August 2015: IVF #3.  14R, 13M, 11F.  Froze 5 blasts for CCS testing.  3 normals.  FET planned for 10/2015.



Baby Birthday Ticker Ticker

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My Ovulation Chart


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Re: Cross-Post: ICSI?

  • We choose to have it done if they weren't fertilizing on their own. Not going through all that work just to give up there, no way.
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  • We consented to icsi, leaving the ultimate decision to use it or not to the lab embryologist. I think my RE does icsi to almost all cycles according to sart data. I'm now in a new city and me new re clinic does icsi quite sparingly (only for mfi). The increased risk of birth defects is extremely low, so that wasn't a major concern to me. Having no fertilization however was a huge concern. So I was fine with the icsi in the end.

    IVF #1 ET 1 d3 embryo 10/30/11 BFP
    3 Embryos frozen (1 d5, 2 d6)

    DS born 07/29/12

    FET #1 ET 1 d5 embryo 02/10/15 BFN

    FET #2 1 d6 embryo didn't survive thaw, transferred last d6. CP :(

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  • FYI- "rescue icsi" often doesn't work very well from what I've read. So better to icsi right away if you are going to go that route.

    IVF #1 ET 1 d3 embryo 10/30/11 BFP
    3 Embryos frozen (1 d5, 2 d6)

    DS born 07/29/12

    FET #1 ET 1 d5 embryo 02/10/15 BFN

    FET #2 1 d6 embryo didn't survive thaw, transferred last d6. CP :(

    image
  • Hi - we chose to let the expert decide (the embryologist).  I guess my H has good swimmers and ICSI wasn't used.  
    Siggy Warning


    TTC#1 since June 2012

    Dx: Unexplained Infertility / AMA

    BFP after 4th IUI cycle with Gonal F + Ovidrel on March 2014 | EDD 12/7/14 | MMC on 4/14/14 

    IUI#5 with Gonal F and Ovidrel trigger on 6/6 - BFN

    On to IVF #1 with a new RE. Started Gonal F and Menopur on 8/15.  Added Ganirelix on 8/24. Trigger on 8/26 for ER on 8/28. 8R 7M 3F.  Transferred all 3 on 8/31. BFP on 9/11 | EDD 5/20/15 - Beta #1: 56.7. Beta #2: 97. Beta #3: 1148. Beta #4: 3559. Beta #4: 7678. MMC confirmed on 10/13. D&C on 10/14 at 9w. Confirmed male with Trisomy 14.

    On to IVF #2 in March. CCS Testing on 2 embies. No go. Waiting to start IVF #3 in July. Surprise BFP on 6/14! EDD - 2/20/16 - Beta #1: 121.4. Beta #2: 236.4. Beta #3: 2014.

    December 4image

  • FYI- "rescue icsi" often doesn't work very well from what I've read. So better to icsi right away if you are going to go that route.
    Oh, wow.  I'd never heard this.  That kind of complicates things.  @Lesliem0901, it kind of sounds like that's what you did.  Even though they didn't end up doing ICSI, did they have a time limit in place or anything like that to ensure that the eggs didn't wait too long?

    Thanks, all.  I shared the responses I've gotten with DH, and he's agreed to reconsider.  I'm calling the RE to discuss it today.
    *****Signature/Ticker Warning******

    Me: 41, DH: 45
    DD, 6/15/2013
    TTC #2 beginning January 2014
    AMH 1.05; FSH range 7-11

    July 2014: IUI #1.  Follistim + Pregnyl.  2 follicles--BFN
    September 2014: IUI #2.  Follistim + Pregnyl + Ganirelix + Crinone.  4(?) follicles--BFN
    October 2014: IUI #3.  More Follistim + More Ganirelix + Pregnyl + Crinone.  4 follicles--BFP!  Beta #1=10 Beta #2=33 Beta #3=97 Beta #4=158.  M/C 11/1/14
    December 2014: IVF #1.  Microdose Lupron protocol.  9R, 9M, 9F.  3 5-day blasts transferred 12/15. BFFN.
    April 2015: IVF #2.  Microdose Lupron protocol.  16R, 15M, 12F. Transferred 2 5-day blasts 4/12 and froze 4--BFP!  M/C 5/25/15
    August 2015: IVF #3.  14R, 13M, 11F.  Froze 5 blasts for CCS testing.  3 normals.  FET planned for 10/2015.



    Baby Birthday Ticker Ticker

    image

    image
    My Ovulation Chart


    image
  • By the way, @Lesliem0901, it's good to "see" you.  We miss you around here!  I hope everything is going well!
    *****Signature/Ticker Warning******

    Me: 41, DH: 45
    DD, 6/15/2013
    TTC #2 beginning January 2014
    AMH 1.05; FSH range 7-11

    July 2014: IUI #1.  Follistim + Pregnyl.  2 follicles--BFN
    September 2014: IUI #2.  Follistim + Pregnyl + Ganirelix + Crinone.  4(?) follicles--BFN
    October 2014: IUI #3.  More Follistim + More Ganirelix + Pregnyl + Crinone.  4 follicles--BFP!  Beta #1=10 Beta #2=33 Beta #3=97 Beta #4=158.  M/C 11/1/14
    December 2014: IVF #1.  Microdose Lupron protocol.  9R, 9M, 9F.  3 5-day blasts transferred 12/15. BFFN.
    April 2015: IVF #2.  Microdose Lupron protocol.  16R, 15M, 12F. Transferred 2 5-day blasts 4/12 and froze 4--BFP!  M/C 5/25/15
    August 2015: IVF #3.  14R, 13M, 11F.  Froze 5 blasts for CCS testing.  3 normals.  FET planned for 10/2015.



    Baby Birthday Ticker Ticker

    image

    image
    My Ovulation Chart


    image
  • The embryologist could've done some, none or all based on what he viewed as optimal state of the sperm. My RE's office doesn't do the rescue ICSI.
    Siggy Warning


    TTC#1 since June 2012

    Dx: Unexplained Infertility / AMA

    BFP after 4th IUI cycle with Gonal F + Ovidrel on March 2014 | EDD 12/7/14 | MMC on 4/14/14 

    IUI#5 with Gonal F and Ovidrel trigger on 6/6 - BFN

    On to IVF #1 with a new RE. Started Gonal F and Menopur on 8/15.  Added Ganirelix on 8/24. Trigger on 8/26 for ER on 8/28. 8R 7M 3F.  Transferred all 3 on 8/31. BFP on 9/11 | EDD 5/20/15 - Beta #1: 56.7. Beta #2: 97. Beta #3: 1148. Beta #4: 3559. Beta #4: 7678. MMC confirmed on 10/13. D&C on 10/14 at 9w. Confirmed male with Trisomy 14.

    On to IVF #2 in March. CCS Testing on 2 embies. No go. Waiting to start IVF #3 in July. Surprise BFP on 6/14! EDD - 2/20/16 - Beta #1: 121.4. Beta #2: 236.4. Beta #3: 2014.

    December 4image

  • Good luck deciding. I know nothing about it but always wishing you well.

    I hope you're doing ok @Lesliem0901‌
  • Hanging in there, @kindershlitz. Hoping you're doing well too!!
    Siggy Warning


    TTC#1 since June 2012

    Dx: Unexplained Infertility / AMA

    BFP after 4th IUI cycle with Gonal F + Ovidrel on March 2014 | EDD 12/7/14 | MMC on 4/14/14 

    IUI#5 with Gonal F and Ovidrel trigger on 6/6 - BFN

    On to IVF #1 with a new RE. Started Gonal F and Menopur on 8/15.  Added Ganirelix on 8/24. Trigger on 8/26 for ER on 8/28. 8R 7M 3F.  Transferred all 3 on 8/31. BFP on 9/11 | EDD 5/20/15 - Beta #1: 56.7. Beta #2: 97. Beta #3: 1148. Beta #4: 3559. Beta #4: 7678. MMC confirmed on 10/13. D&C on 10/14 at 9w. Confirmed male with Trisomy 14.

    On to IVF #2 in March. CCS Testing on 2 embies. No go. Waiting to start IVF #3 in July. Surprise BFP on 6/14! EDD - 2/20/16 - Beta #1: 121.4. Beta #2: 236.4. Beta #3: 2014.

    December 4image

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