Infertility

MFI Question--Urology?

Hey ladies, 

I am in full on research mode between cycles and thinking about getting second opinions. I am curious about those of you who have DH dealing with MFI issues. I have heard of some MFI patients being referred to urologists. Can anyone shed light on what a urologist evaluates outside of the SA? I know @carrieharry79, you said your DH saw a urologist to rule out other issues. What are the "other issues" that are being ruled out? I'm trying to assess if it would be a good idea to send DH to a urologist. He has severely low morphology and no other known issues (except we have had three failed cycles).  

Thanks for any insight! 
Me: 28, no diagnosis  DH: 33, MFI, severely low morphology, diagnosed 3/14
IVF #1: May/June 2014: 10R/8F, 1 morula transferred = BFN, nothing to freeze.
IVF #2: July/August 2014: 18R/12M/8F, 2 blastocysts transferred = BFN, nothing to freeze.
IVF #3: October/November 2014: 22R/17M/15F, 2 early blastocysts transferred = BFN, nothing to freeze.

Re: MFI Question--Urology?

  • My DH is seeing a urologist due to his diagnosis of kleinfelters and he has SA's and actually is on clomid to see if we can get more sperm to freeze :) good luck!
    Ashley & Jeremy 10/10/10

    MFI, 50k sperm frozen, RE requires weight loss before our first cycle of IVF so now we wait.

    (+20 = total loss)
    11440622

  • DH went to rule out any varicose veins and had some labs drawn.


    image




    Me: 33, DH: 35
    Married 10/13, TTC since 7/13
    Dx: MFI
    IUI #1 7/14: BFN
    IUI #2 8/14: BFN
    IVF #1 11/14: 20R17M15F
    Transferred 1 three day embryo! 7 frosties!
    BFP!  EDD 7/27/15



                                                                      image

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  • DH's Uro did a physical exam (including the prostate...fun), which is when he found the varicocele.  He also did a blood test to see where his T levels were at (which were low).
    Me (28): fine, DH (28): MFI
    Married 6/21/09
    Off BCP and TTC 4/17/11
    BFP #1 (ended in CP) 7/15/11
    Varicocelectomy surgery 9/4/12 - T improved to normal, but still low count

    Current Status: Pursuing Jan '15 IVF w/ ICSI
    Lilypie Angel and Memorial tickers


    image    imageimage
  • DHs urologist did a physical examination, ultrasound, and hormone panels in addition to regular bloodwork. Poor SAs can be a symptom of something else going on, so getting a full work-up is generally a good idea. Sometimes it's treatable (usually not, but sometimes! And they're working on that!) to the point of getting the sperm up to snuff, but it doesn't hurt to get checked out.

    In our case, DH was found to have low T and hemochromatosis, in addition to being partly unexplained MFI. They were able to treat the low T with Clomid, and that brought his numbers up quite significantly, but post-wash counts were still too low for IUI due to other factors.

    image imageimage
    image

    ***EVERYONE WELCOME***
    TTC #2 with assistance since 03/11
    Me: 33, Autoimmune (Hashimotos and FMS/CFS)
    Treated with Synthroid, acupuncture, TCM and supplements
    DH: 33, MFI (very low on all counts, high antibodies, hemochromatosis)
    Many treatments tried, none successful

    IVF/ICSI #1 05/14 - EPP/Antagonist, Gonal-F and Luveris, 18R, 14M, 13F - SET of 1BC, all arrested on day 5 - C/P
    Genetic testing = normal, DNA Frag = excellent
    IVF #2 03/15 - Long protocol with Suprefact, Gonal-F, and possibly Luveris, adding in PICSI
     
  • I don't think there is much they can do to fix anything but it's a good idea to rule out something serious.
  • I don't know everything they were looking for, but they did do a full exam. We were worried about varicocele, but it turned out not to be an issue. They wouldn't even continue our testing at MGH until DH saw the urologist.
    Our story:
    Married 7/2013 - been TTC ever since
    Me: 35 - normal test results
    Husband: 30 - Concentration:10.8 Million/ml, Motility: 16%, Progressive Motility: 9%, Morphology: 3%
    First started talking to fertility specialist in 4/2014
    IVF #1 
    11/13 - 19 retrieved, 18 ICSI, 15 fertilized. 
    Transfer 11/16 - 1 blastocyst transfered, 3 frosties
    11/28 - Beta #1 BFP! 12dp5dt beta 1,699
    11/30 - Beta #2 14dp5dt 3,400 
    12/8 - No signs of baby at first U/S (6 weeks)
    12/15 - yolk sac, fetal pole and heartbeat all there! I'm still pregnant! One girl, due 8/4
    Image and video hosting by TinyPic
    BabyFruit Ticker
    All are welcome!


  • DH saw a urologist early on in our journey. They did a physical exam and found a cyst which they were afraid was an actual blockage. DH had to the an ultrasound abs cyst wasnt blocking anything and posed no risk. They also did labs and found a slightly decreased T level. Urology is actually who moved us onto our RE. DH is on clomid now in hopes of increasing numbers. I've seen great success on this board. We go again in February so we will see. Best of luck! !!
  • We were referred to a Urologist by our RE after DH first SA came back at a count of 10,000. They couldn't determine morphology because of the low count. The Uro does hormone testing, genetic testing, a full exam to check for obstructions or varicoceles. DH was on clomid for 6 months with unfortunately no improvement and then switched to hcg and hmg injections. We were also given a vitamin regimen to improve sperm quality and motility. Good luck!
    Me:33 DH:34
    TTC Since:May 2013
    SA:Count 10k Motility >50 Morphology?
    Dx:MFI
    IVF set for Nov 2014
    -(10/31)canceled due to azoospermia (0 count)
    DH in treatment-waiting for count to improve

    image


  • Ladies--I really appreciate these responses. It makes me wonder why we weren't advised to take this step sooner. 

    Me: 28, no diagnosis  DH: 33, MFI, severely low morphology, diagnosed 3/14
    IVF #1: May/June 2014: 10R/8F, 1 morula transferred = BFN, nothing to freeze.
    IVF #2: July/August 2014: 18R/12M/8F, 2 blastocysts transferred = BFN, nothing to freeze.
    IVF #3: October/November 2014: 22R/17M/15F, 2 early blastocysts transferred = BFN, nothing to freeze.

  • KM721 said:
    Ladies--I really appreciate these responses. It makes me wonder why we weren't advised to take this step sooner. 


    I don't know about the rest of the women here, but our first RE really brushed us off with us even asking for a referral. She said it wasn't necessary, and that we'd have to do IVF anyways. Yes, she was right in the end that we'd still need IVF, but we're the type of people that will try and solve the underlying issue, rather than treat the symptoms. Without the referral, we wouldn't have caught DHs health issues! We're much happier at our current RE, who works with us and wants us to do everything we can, rather than just throw treatments at us.
    image imageimage
    image

    ***EVERYONE WELCOME***
    TTC #2 with assistance since 03/11
    Me: 33, Autoimmune (Hashimotos and FMS/CFS)
    Treated with Synthroid, acupuncture, TCM and supplements
    DH: 33, MFI (very low on all counts, high antibodies, hemochromatosis)
    Many treatments tried, none successful

    IVF/ICSI #1 05/14 - EPP/Antagonist, Gonal-F and Luveris, 18R, 14M, 13F - SET of 1BC, all arrested on day 5 - C/P
    Genetic testing = normal, DNA Frag = excellent
    IVF #2 03/15 - Long protocol with Suprefact, Gonal-F, and possibly Luveris, adding in PICSI
     
  • Thanks, @tptbabe. I appreciate the advice. DH actually has a PPO plan, so we just scheduled with the Urologist who came highly recommended off of this board. Hopefully we will gain information and rule out some things at the very least. It is frustrating that there is not more collaboration between different approaches with some REs. 
    Me: 28, no diagnosis  DH: 33, MFI, severely low morphology, diagnosed 3/14
    IVF #1: May/June 2014: 10R/8F, 1 morula transferred = BFN, nothing to freeze.
    IVF #2: July/August 2014: 18R/12M/8F, 2 blastocysts transferred = BFN, nothing to freeze.
    IVF #3: October/November 2014: 22R/17M/15F, 2 early blastocysts transferred = BFN, nothing to freeze.

  • Great news! Even if they end up not finding anything, you'll feel better knowing that you did everything you could :)
    image imageimage
    image

    ***EVERYONE WELCOME***
    TTC #2 with assistance since 03/11
    Me: 33, Autoimmune (Hashimotos and FMS/CFS)
    Treated with Synthroid, acupuncture, TCM and supplements
    DH: 33, MFI (very low on all counts, high antibodies, hemochromatosis)
    Many treatments tried, none successful

    IVF/ICSI #1 05/14 - EPP/Antagonist, Gonal-F and Luveris, 18R, 14M, 13F - SET of 1BC, all arrested on day 5 - C/P
    Genetic testing = normal, DNA Frag = excellent
    IVF #2 03/15 - Long protocol with Suprefact, Gonal-F, and possibly Luveris, adding in PICSI
     
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