And a big fat negative as I knew. Took tests 5dpt and this morning 6dpt and got negatives. Blood test confirmed it this morning. Annoyed and glad I'm off a little early tonight so I can drink lots of wine and sit in the hot tub with dh.
One more try with our two remaing embryos I'm guessing jan or so. So over this and ready to be done with this chapter of life!
Me 34 and DH 39 married in aug. 2002
Did 5 round of clomid 2010 =BFN
High levels of NK CELLS DX sept.2012 DOR:# 0.02
IVF #1 May 2012 ER 4, EF 2, ET 2 =BFN
MINI IVF Oct.2012 Cancelled 10-27-12
Ivf #3 Antagonist Protocol April 2013
Shared cycle..Donor cycled in July Got 12 eggs 9 fertilized and 8 frozen!!
DE FET #1 Sept. 3rd 2013 FIRST BFP EVER 5dp5dt
miscarried Sept 24th at 5 weeks 5 days
Etopic D&C and hysterscopy Nov 5 2013
dx with pre genetic blood clotting dec 2013
FET #2 Jan 31st 2014
Miscarried for a second time again at 5 weeks 5 days
Currently fostering to adopt an amazing little 1 year old boy..P.J!
FET#3 is Oct 29th 2014
BFN on fet #3
Last and FINAL FET coming JAN 28th 2015
Everyone Welcome
Re: Beta results are in...
Me (32) DOR, elevated NK Cells/ 2 copies of MTHFR mutation/ MH (35) azoo/high DFI (TTC#1 since 2009)
IVFs#1-4: (4/10-2/12) all BFN
Surprise Bfp (9/11) - c/p
DS IUI#1-2 (9/12, 10/12) - BFN
DS IVF: (11/12) - BFN
DE/DS IVF#1: (10/13) - 2 day 3 embies transferred-BFFN
FET of 2 day 6 blasts: (12/13) - c/p
DE/DS IVF #2: (4/14) - 1 day 5 blast transferred...BFFN...again.
FET 5/14: 1 day 5 hatching blast transferred...another BFFN
Repeat SHG 6/14-normal / Endometrial Receptivity Array biopsy 7/14-Receptive Uterus
New RE, additional testing reveals elevated NK Cells
FET of 1 day 5 blast (RE recommends transferring 1 due to elevated NK cells) with lovenox, steroids & intralipids in October
*******siggy/ticker warning*****
Me(31). DH (31)
DH SA normal count and motility, 1% morphology
Me .72 AMH, Fragile X premutation carrier
IVF #1 (6/12/13) BFN
IVF #2 (8/16/13) BFN
FET 10/4/13 Chemical
IVF #3 MC 5 weeks 5 days
IVF #4 DE 11/7 BFP, edd 7/28/15
All Welcome
TTC #1 since August 2011
My Blog
September 2012: Start IF testing
DH (32): SA is ok, slightly low morph, normal SCSA Me (32): Slightly low progesterone, hostile CM, carrier for CF, Moderately high NKC, High TNFa, heterozyogous mutated Factor XIII, and +APA
October 2012-May 2014: 4 failed IUIs, 3 failed IVFs, and 1 failed FETw/donor embryos
November 2014: IVF w/ICSI #4 Agonist/Antagonist with EPP and Prednisone, Baby Aspirin, Lovenox, and IVIG for immune issues. Converted to freeze all due to lining issues. 2 blasts frozen on day 6!
January 2015: FET #2 Cancelled due to lining issues
April 2015: FET #2.1
PAIF/SAIF Welcome!
Me & DH (33), 3 Furbabies, TTC since October 2011
Day 3 #’s (Dec 2012) FSH 9, AMH .77, LH 2.4, E2 31, AFC 9
DX: Me-DOR + No Tubes, DH-Fine
Ectopic 2007; lost tube/2nd tube removed Dec 2011 (hydro)
April 2012=IVF#1- EPP Antag+ICSI, 2R,0F (BFN), Now dx’d with DOR.
June-July 2012=IVF#2- MDL+ICSI&AH, 8R,4M,3F (BFP 9dp3dt) Beta#1 at 11dp3dt=36, Beta#2 at 15dp3dt=156, Beta#3 at 19dp3dt=671, dx'd with SCH, no growth-m/c at 7wks/Lap Dec 2012 to remove small fibroid.
Feb 2013=IVF#3-MDL, 2/1=baseline, started 10 units mdl, AFC-7, 2/3 start gonal f, self cxld cycle b/c of low e2.
April 2013=IVF#3.5-(with new RE)AG/ANT Conv + ICSI. 4/10-4/23 bcp's, 4/20-4/27 lupron, 4/28-ganirelix until end of stimming, 5/2-600 gonal f, 5/4-add 1/2 vial menopur, 5/13-ER (9R,1M,1F), 5/17-ET, 1 beautiful 8 cell (please be my sticky baby!!!!) 5/28-BFFN.
Oct 2013=IVF#4-LLP+ICSI &AH, 10/14 (6R, 2M, 2F), 10/17-ET, 1 seven cell & a six cell, BFP at 9dp3dt, 1st beta=56, 2nd beta=52, CP.
Jan 2014=IVF #5-LLP, Cxld after 6 days of stims due to fast response and lead follicle.
March 2014=IVF 5.5-LLP, Lupron 3/10, BL 3/18, 11 days of stims, Trigger 3/29, ER 3/31. 7R, 2M, 2F. ET 4/3. Txfd one 5 cell & one 9 cell. BFP on hpt from 7dp3dt & on. Praise be to God. Beta #1 at 11dp3dt=106, #2 at 13dp3dt=239. First u/s 4/28, measuring on track & heartbeat seen. 5/5-2nd u/s, measuring on track with strong heartbeat. 5/12- 3rd u/s & released from RE. Grow baby grow, we love you! Baby G&T is a BOY! Born 12/2014 via c/s! 8lbs, 8oz & 21 inches.
*******Ticker Warning**********
"God's Delay is not God's Denial"
TTC#1 since April 2011
IVF#1 July 2012 5R, 3 made it to blast, sET c/p
FET#1 Aug 2012 2 blasts transferred BFN
IVF#2 Oct 2012
16R/6M/6F/2-8 cell grade 1 transfer
Beta 1-237.9, Beta 2-566, Beta 3-8657
US 6w3d shows one baby w/ HB 115
US 7w1d no more heartbeat/ D&C 11/30/12 normal karyotype
IVF#3 Mar 2013
6R/4M/4F 1 compacting and 2-8 cell transfer
ectopic pg MTX given 3 month break from TTC
IVF#4 Sept 2013--BFN
http://i61.tinypic.com/34zll06IVF#5-7 Apr 2014, Jun 2014 and Aug 2014 banking embryos for CCS testing. Praying for normals!
***signature & ticker warning***
Me: 30 ~ Stage IV Endo ~ AMH .38 ~ AFC 8
AMH .97 as of 4/2012! ~ AMH 1.63 as of 4/2013!?!
Him: 29 ~ perfect swimmers
Laparotomy w/partial oophorectomy 8/2009 to remove cysts/endo.
Stopped BCP 4/2010.
Multiple clomid rounds from 11/2010 to 6/2011. ~ All BFN
IUI w/clomid 7/2011. IUI w/clomid & injectables 11/2011 & 1/2012. ~ All BFN
IVF:EPP 5/2012 ~ (4R, 3M, 2F w/ICSI). Both embryos txfrd. ~ BFN
BCP to manage endo from 10/2012 to 12/2012.
FET w/donor embryos #1: 10/2013 Cancelled
FET w/donor embryos #1.2: 11/2013 ~ ET of 2 beautiful blasts on 11/27.
Beta 1: 503(12dp5dt) Beta 2: 1035(14dpt) Beta 3: 3001(16dpt) Beta 4: 8503(19dpt)
Twins with an EDD of 8/15/14! Team Purple
G&B born 6/30/14 at 33w3d via emergency c/s.
If you're wondering about my avatar...it's a fried pickle chip shaped like a fetus!
I'm so, so sorry, Lacy.
My BLOG: www.ivfbabyquest.wordpress.com -Update - old blog.
PAIF/SAIF Welcome!
Me: 42, Hubby: 35, TTC since Jan 2010. Dx: DOR due to advanced maternal age. Also: Hypothyroidism (100mcg Levothyroxin). Positive for MTHFR (hetero-C677T), Factor V Leiden, and Fragile X (on DH side). Taking pre-natal vitamins.
First natural PG 9/27/11; mc: 1/20/12
First RE visit: 8/8/12, Saline Sonogram: 8/28/12, IVF injection class: 10/11/12, add FaBB Tab for FVL, +Vitamin D.
IVF #1: 10/17/12 Baseline: FSH- 9.4, E2- 24, LH- 3.7, Prog- 0.3 The u/s showed 6 follicles in my right & 9 in my left. Rx: 150 Bravelle & 150 Menopur SQ nightly. 10/21/12: Add Ganirelix SQ every morning.
ER 10/28/12: 13 Retreived. 7 Mature. 6 Fertilized. 5 Made it to PGS. ET 11/2/12: CANCELED. All 5 came back from PGS as having "severe abnormalities."
IVF #2: 1/7/13 Baseline: FSH- 8.8, 4 follicles in my right & 6 in my left. Rx: 150 Bravelle & 150 Menopur SQ nightly. 1/11/13: Add Ganirelix SQ every morning. hCG Trigger 1/16/13
ER 1/18/13: 9 Retrieved. 5 Mature. 5 Fertilized. 2 Made it to PGS. ET 1/23/13: CANCELED. All embryos (he even sent the ones not growing) came back from PGS as having "multiple severe abnormalities."
IVF #3: NEW RE! 3/1/13 Baseline: FSH- 9.6, E2- 61, Prog- 0.94, 3 follicles in my right & 4 in my left. Rx: 150 Bravelle& 150 Menopur SQ in PM. 3/7/13: Add Ganirelix SQ in AM. hCG Trigger 3/9/13 SQ.
ER 3/11/13: 6R, 2M, 2F. Day 3: one 8 cell, grade 0. Five day ET 3/16/13: one early blast, grade Fair. 3/24/13 AF came a day before beta. BFN
IVF #4: (Added acupuncture to this cycle.) 3/25/13 WTF & Baseline: FSH-11.8, E2- 56, Prog- 0.84 3/26/13 Start stims. 3/30/13 u/s: 5 follicles in my right & 4 in my left. Rx: 225 Bravelle& 225 Menopur SQ in PM. 3/31/13 Add Ganirelix SQ in AM.hCG Trigger 4/3/13 SQ.
ER 4/5/13: 5R, 3M, 3F naturally. Day 3: two 8 cell, grade 0, one 8 cell, grade 2 (Scale 0-best to 3-worst). Five day ET 4/10/13: two blastocysts (the 3rd stopped growing.) Beta 4/18/13: 2.5 BFFN. RE recommends we stop trying and focus on living childless, due to the extremely poor quality of my eggs.
***Decided to stop trying and live CFNBC. I couldn't adjust. So, six months later...
IVF #5: Changed RE. Going to one of the big name clinics now. OWDU: 10/29/13. Update: HORRIBLE experience. Disgusted and distraught at their complete unprofessionalism and how much money and precious time they cost us. Sickening. Have now changed RE again. New Patient appt. 1/30/14.
BFP! Out of nowhere, I got KU the old fashioned way! POAS 1/26/14 - Positive! FDLM 12/30/13. Beta #1 16dpo= 373. Beta #2 18dpo= 801. EDD 10/6/14
2/4/14 1st U/S revealed a 5wk2day sac but no fetal pole. Started 200mgs of progesterone suppositories daily
2/11/14 2nd U/S revealed a perfect 6wk1day "diamond ring" embryo with a beating heart! 138bpm! Add 1mg folic acid and 40mg Lovenox
2/25/14 3rd U/S: perfect 8w1d embryo, 178bpm. 3/6 start spotting. 3/11 10w1d U/S shows no heartbeat. Scheduling D&C. The Stork has forsaken me again.
IVF #5.2: New in-state RE. Supplement priming for 1.5 cycles prior to start of cycle, including DHEA 50mg (stopped 5/15), CoQ10 200mg 2x/day, L-Arginine- 1000mg 2x/day (stopped 6/5 due to cold sore!), myo-inositol- 2g 2x/day, melatonin- 3mg, and Neevo (prenatal for MTHFR).
5/16/14 Day 2 bw cycle prior: FSH- 12.22, E2- 38.37, Prog- 1.35, LH- 9.46. 6/2/14 Day 19 bw: Prog- 23
6/12/14 Baseline: E2- 122.7, Prog- 0.4. 5 follicles in left, 4 follicles in right. Start stims: 375IU Follistim & 150IU Menopur. 6/19 Increase Follistim to 425IU, Menopur still 150IU. 6/18 add Ganirelix. 6/23 Ovidrel trigger SQ. 6/25 ER: 8R, 8M, 5F naturally. Start Medrol & Doxy. 6/26 Start Endometrin. 7/2 Start Lovenox.
7/8/14 Beta= 137.4 BFP!!! (My first from IVF!) E2- 1109, Prog- >60. Stop CoQ10, myo-inositol, and melatonin. 7/9 2nd Beta= 281.4. TSH- 2.70. Increasing Synthroid to 100mcg daily. 7/24 6w3d u/s measured 6w3d, hb: 121bmp! 8/5 8w1d u/s measured 8w3d, hb: 164bpm! Graduated from RE to OB. Now I just need to find an OB!
EDD 3/18/15!
Anovulatory cycles, increased Synthroid Diagnosed Sep 2010
1 Clomid/Ovidrel BFN May 2011
Natural cycle Aug 2011 BFP M/C 4 Weeks
1 IUI Sept 2011 BFP M/c 7 weeks
Provera Dec 2011 BFP M/C 3 Weeks
IVF March 2012 BFP m/c 4weeks 5 days (IL, Prednisone)
IVF#2w/DS July 2012 MEGA FAILURE BFN (IL, Dexamethasone)
Diagnosed No real HLA Match, DQ Beta Triad, High TNF, Low NK Cells
Oct 2012 Natural Cycle m/c 4wks (Lovenox, Prednisone)
Went to Beer Center- high tnf, low lad, implantation failure
Jan 2013 BFP
Humira,LIT,Prednisone, Lovenox, IVIG, Baby Aspirin
Miracle Born August 2013 Premature
Yours doesn't have to be a sad story
10/11: after 2 years, saw a RE, FSH 5.4
11/11: BFP! (surprise after thyroid & normal hsg),
12/11: missed m/c after 7 week u/s, 1/12: D&C
6/12 IUI#1-IUI #3: clomid = BFP!, C/P
IVF #1(10/12) FSH 5.4, AFC: 16 long Lupron, 5R/5M/4F, all 4 made it to 5dt, 1 blast/1-8 cell transferred=BFN
IVF #2(12/12)AFC 21, MD lupron, 4R/4M/3F, 5dt of 1 blast and 2-8cell. BFN.
IVF#3(4/13) Natural start antagon protocol, 12R,11F. one PGS normal at day 6 transfer. BFN.
IVF#4 (11/13) C.CRM (ODW.U normal 8/13 Still no Diagnosis) EPP/antagonist. ER 13R/7M/6F. Only 1 made it to freeze. Abnormal. Looking into options of DE, Fresh vs frozen.
10/14 new local RE to look into what's next. CD3 FSH 4.7, AMH 0.9. Met with DE agencies and exploring options for feb/march 2015.
Surprise natural bfp (4 days before donor is signed). Beta #1 at 9dpo: 51.8, 2nd beta: 195 (25 hours doubling) @11dpo. 3rd beta (12/15): 516 (35 hrs doubling) 4th beta(12/17): 895 (58 hours doubling) 5th beta(12/19): 2120. U/S at 5w0d(12/22): one gestational sac with yolk sac. U/S #2 (6w0d)12/29. One little bean measuring 6w0d with HR 124. 3rd u/s(1/4)7w0d: baby measuring 7w2d. HR 134. 3/30: A/S at MFM went great except for low lying placenta. Verifi results are normal! Team Blue! Please send any positive thoughts our way! EDD:8/24/2015
Baby Will born 8/18. He's perfect.
More hugs. It's just awful when DE keeps failing.
TTC #1 since 8/1/10; Me:41 and BRCA1+, DH:46
DOR (FSH 24.3)/ terrible egg quality ; homozygous MTHFR c677t
5 IUI's: 2/11 to 6/11 and 1/12= BFN
OE IVF#1-4 8/11-6/12= all BFN
DE IVF#1 11/12 bad embryos= BFN
DE IVF #2 2/13 BFP/Beta hell: m/c 5w6d
CFNBC 7 months, not doing well; decided on guarantee program at RBA w/frozen DE
DE IVF #3 1/14 ET 4BB; BFP;M/C 5w1d, incomplete m/c; MVA extraction in ER 7w1d
DE FET#1 ET 3/1714; BFP, beta 1 3/27= 197, beta 2 3/31= 1586, beta 3 4/7= 13879!!
First u/s= Twins with HBs at 6w2d! We are Team Pink x 2!!
K & K born 11/21/14 at 38wks 4 days
SAIF/PAIF Welcome
http://waitingforraintostop.wordpress.com
Feeling pretty low and defeated right now.
Wondering if I will be that one who ivf just will not work for. I need to let go and give it my one last try and be done. May take a little break from bumping for the holidays. Good luck to you all and happy holidays!
((Huge hugs)) Lacy!!
Have you considered seeing a RI before your next transfer?
Hang in there!! Wishing you comfort at this time. Failed cycles are hard, but like McIrish said, it is that much harder when a DE cycle doesn't work, because it's supposed to be the answer. ((More hugs)))
::: Married June 2003:::
TTC #1 since: Aug. 2008
Me: 34, DOR, MTHFR-A1298C (heterozygous), decreased blood flow to uterus, Mild Endo
DH: 38, Balanced translocation 5&10, unexplained MFI, normal SA and SCSA
Tx History: IUI 1&2= BFN
IVF# 1 W/ICSI= BFN
IVF# 2: cancelled d/t no response
IVF# 3= 1 egg retrieved=immature/not viable
IVF# 4= c/p
***CCRM ODWU***
Found DHs BT and Me-decreased blood flow to uterus
Recommended DE IVF w/PGD, incorporate electro-acupuncture. Decided to cycle locally
***New RE***
DE IVF# 1(cycle #6) w/pgd, (freeze all): 30R, 23M, 15F, slow/poor embryo development, 4 biopsied, 1 Normal "Norm"; DE IVF w/PGD, incorporate electro-acupuncture.
IVF# 6: (OE/DS) cancelled
IVF# 7: (OE/DS) 1R, 1M, 1F, arrested day 5
Plan-DE IVF# 2 (cycle #8): DE/DS in May 2015
http://icanhazbabyz.blogspot.com/
Very very sorry. It hurts to go through it once let alone multiple times. Im hopeful for your other two. Hugs for you and your dh
Age: 35 TTC since 2005, MFI & DOR
IVF #1 Sep '11 - canceled poor response
IVF #2 Nov '11 8R/8M/4F 3dt x2 - chemical
IVF #3 April '12 11R/6M/4F 3dt x2 - m/c
FET #1 Aug 2012 3dt x2 - BFN
**new RE**
IVF #4 Jan '13 BFN 11R/6M/6F 5dt x2 - BFN
IVF #5 July '13 16R/10M/10F 5dt x2 + 1 frostie
9dp5dt Beta 1 = 344!! 16dp5dt. Beta 2 = 4822 7wk u/s= 2 heartbeats!
Twin girls! 3/6/14
TTC summer 2008
Diagnose me. DOR, DH perfect
IUI # 1 6/2010, BFN
IUI # 2 8/2010, BFN
IVF # 1 10/2010 Canceled poor response
IVF 1.2 12/2010 BFP! mc 6 weeks 2 days
Mental health break for 10 months
IVF # 2 10/2011 BFN
IVF # 3 5/2012 BFP! 10 eggs retrieved (best ever)
7 fertilized transferred 3
Beta #1 14dpo - 72, Beta #2 17dpo 145 Beta 3 20dpo 521
First u/s June 15 saw HB 126 bpm missed m/c 7/5/12 10 weeks D&C 7/6/12
IVF#4 ER 9/30 ET 10/3 Beta 10/16 BFFN. IVF #5 final with o/e. ER 1/21 only 1 retrieved, hoping my lonestar is the one. Beta #1 2/6/13 = 209.... please let this be it! Keep growing lonestar! Beta #2 2/8/13 - 586! , Beta #3 2/10/13 = 1898. First u/s perfect little heart beat at 116 bpm. Measure 6 weeks 1 day. EDD 10/14/13
3/4/13 measuring right on track beautiful heartbeat 171 bpm, graduated from RE to OB... bittersweet.
PAIF/SAIF always welcome! Its a girl!
TTC#2 No birth control since DD was born. Getting ready to jump back in the saddle. Weaning this month. RE
appt scheduled 5/8. Here we go again!
11/13 beta #1 924!!! 2nd bet 11/15 1906, one more on 11/17 3rd & final beta 3430. First u/s 12/5, 7w4d, 2 heartbeats,
~SAIF/PAIF/Everyone Welcome~
Me= 37 and DH = 41
Dx: DOR, Endo, APA+ (really high beta 2 glycoprotein antibody and high everything else tested), heterozygous MTHFR mutation, positive for lupus anticoagulant, high FSH, low AMH and both tubes blocked (per HSG on 3/8/11)
IVF #1 - long lupron (with HGH, intralipids, lovenox and BA); 4 retrieved, 3 fertilized; ET 2 blasts and 1 frozen = BFN
IVF #2 - a version of antagonist with EPP (with HGH, intralipids, lovenox and BA); 6 retrieved, 4 mature, 3 fertilized, 2 blasts and 1 frozen blast transferred on day 5 = BFN.
IVF #3 April was postponed to May, May was canceled. June/July was canceled. Had a cyst aspiration and then began IVF #3 in August. ER on 8/22; ET on 8/24 with AH. +HPT on 9/5. Beta #1 (11dpo) = 3; Beta #2 (15dpo) = 29; Beta #3 (17dpo) = 60; Beta #4 (19 dpo) = 118. Heartbeat at 6 weeks 6 days =132. Lil is here!
TTC#2: Trigger + TI = BFN; Clomid + Trigger + IUI = BFN.
IVF #4: BCP + MDLF + Lovenox = 7R, 1F = Transferred 1 6-cell embryo on day 3 = BFN
IVF #5: MDLF + Lovenox = 4R, 1F = Transferred 1 10-cell compacting embryo on day 3 = BFN
IVF #6: (New RE): Long Antagonist November 2014 (transferred two 8 cell grade 1 embryos and froze one blast) = BFN
FET#1: BFN
So sorry Lacy. I hope the next one is your take home baby!
3 Clomid IUIs -- BFNs
IVF #1 never made it to transfer
On "egg health" cocktail DHEA/CoQ10/FRC/Pregnitude/Melatonin
Starting IVF #2 for Feb 2013
Follistim/Menopur/Ganirelix
Cancelled mid-cycle due to high P4 levels early on.
OCPs again for IVF 2.5 mid-March. IVF 2.5 transferred two "gorgeous" 5-day blasts and BFFN. Even REI is baffled
On indefinite hold until a huge stroke of serendipity led me to IVF 3 May 2014
Testing found positive cardiolipins/APS, now on lovenox and intralipid infusions
Transfer of 2 5-day blasts and (FINALLY) BFFP!! 1st ultrasound shows two sacs and two HB, but one is sluggish, almost expecting vanishing twin Subsequent ultrasound confirmed vanishing twin, but my other Little critter looks fantastic!
"You may have to fight a battle more than once to win it."
-- Margaret Thatcher