June 2015 Moms

Unisom/ B6 combo work for nausea?

juliep91080juliep91080 member
edited November 2014 in June 2015 Moms
Has anyone tried this? My dr recommended it to me to help with the all day morning sickness.

Re: Unisom/ B6 combo work for nausea?

  • Yep. Diclegis is the prescription form. It has made a HUGE difference for me. 
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  • yes. it's been a lifesaver for me. I'm finally ready to go back to work after two weeks in bed with mind-numbing nausea.  It's safe up to a pretty high dosage (I now take 1 tablet unisom + B6 at night, 1 tablet unisom + B6 in the morning, and .5 tablet unisom + B6 in the afternoon); it's been studied up to 120 mg of doxylamine (unisom) per day with no increased fetal risk or adverse events.

    TTC#3: started September 2014; BFP on 10/1/14; EDD 6/10/15
    TTC#2: started June 2014; BFP on 7/22/14; EDD 3/31/5; MC 8/3/14
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    CRB (aka L): born 3/21/11 (35 weeks, 5 weeks in the NICU)
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  • Yes. Its amazing. Its my little miracle cure nothing else has helped so far.
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  • Did you all call your OB first for approval and dosage? I'm thinking about trying this, but wasn't sure if I needed to call first.
  • Yes!! It made my nausea completely go away the first week.  It's back a bit but not as bad.  I didn't call my dr before taking it.

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  • kmleon83kmleon83 member
    edited November 2014
    May have to look into this. My OB gave me some samples of Diclegis and they worked so wonderfully... I went to the pharmacy to put in the prescription and my insurance company is giving me a REALLY hard time of covering the cost so I've been without since last Wednesday. This weekend was miserable. :(
    kristine!  B)

    me: 33, Factor V Leiden, MTHFR + hubs: 37
    BFP #1: 9/25/14 -- EDD: 6/4/15
    Jesse, our baby boy: 2/25/15 @ 25.6 weeks, 2lbs 2oz & 13.5 inches. spent 66 days in the NICU. <3
    BFP #2: 7/29/16 -- EDD: 3/30/17


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  • junch817junch817 member
    edited November 2014
    herbavein said:

    yes. it's been a lifesaver for me. I'm finally ready to go back to work after two weeks in bed with mind-numbing nausea.  It's safe up to a pretty high dosage (I now take 1 tablet unisom + B6 at night, 1 tablet unisom + B6 in the morning, and .5 tablet unisom + B6 in the afternoon); it's been studied up to 120 mg of doxylamine (unisom) per day with no increased fetal risk or adverse events.

    How in the world do you function with that much Unisom? I mean, I 100% support you finding the combo that works for you, but I am dead to the world with a half pill in the day. I wouldn't be able to even open my eyes if I took that much lol

    ETA and my nausea is pretty terrible too. I totally empathize with you on the mind numbing nausea.
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  • I will have to try this. Unisom during the day? Does this make you even more exhausted than usual?
  • junch817 said:
    yes. it's been a lifesaver for me. I'm finally ready to go back to work after two weeks in bed with mind-numbing nausea.  It's safe up to a pretty high dosage (I now take 1 tablet unisom + B6 at night, 1 tablet unisom + B6 in the morning, and .5 tablet unisom + B6 in the afternoon); it's been studied up to 120 mg of doxylamine (unisom) per day with no increased fetal risk or adverse events.
    How in the world do you function with that much Unisom? I mean, I 100% support you finding the combo that works for you, but I am dead to the world with a half pill in the day. I wouldn't be able to even open my eyes if I took that much lol ETA and my nausea is pretty terrible too. I totally empathize with you on the mind numbing nausea.
    THIS!  It's helping with the nausea (at least I'm a bit functional and can make it to work.). I'm taking 25 mg of B6 morning, afternoon, & evening, but I am only taking half a unison (so 12.5 mg) at night and it knocks me out COLD.  As in I feel like I have a hangover in the morning.  I don't think I could drive to work if I took it during the day.  I'm going to try taking 1/4 unison tonight and see if that works for the nausea.  But half a pill puts me right to sleep.

    Although, tired and passing out is certainly better than hugging the toilet.  :-(  I'm so ready to be past this part.
    -Emma

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  • I'm going to have to try it. I was taking Zofran but didn't work for me! This nausea all day everyday is killing me and I feel bad for my 3 year old :(
  • What does anyone think about taking unisom at night, and Zofran during the day? The unisom was doing nothing for me throughout the day, so my doc gave me Zofran. I slept TERRIBLY with the Zofran because I was still soooo nauseous. But that next day I kept up with it, despite still feeling really bad, I was able to eat more than I had in WEEKS. But come night time, again, no sleeping because I still felt so bad.

    Would taking unisom/b6 at night and Zofran for the day be ok? I realize not asking doctors, but I wanted your thoughts because I know a lot of us have been playing around with stuff trying to figure out what works best for each of us.

    Also apologies to @juliep91080‌ for piggybacking on your post. I thought this question might apply to others and thought it might get lost in the symptoms thread. Hope that is ok!
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  • I take the combo and it is a life saver for me I was hugging the porcelain throne 3 times a day


    Baby #1 Lost to HELLP Syndrome at 24 weeks.

    Baby #2 due 6/11/15 soooo excited!!!!

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