Infertility

Extremely High E2 Level OHSS Q

Hi Ladies. I ran a search through our IF board but only seem to find women who had mild OHSS or were just concerned that it would occur. Yesterday my E2 level was over 5,000 and I triggered with 10,000 HCG last night. I have never seen anyone with E2 this high. I know the normal Gatorade and high protein diet can help... anything else that you all can think of? Anyone have an E2 level this high before? I'm doing a freeze all cycle. TIA!  
SIGGY WARNING//TICKER WARNING//PAIF

Long of the Short:
 TTC since April 2013  DH 42 y/o I'm 30  Dh had vasectomy reversal Feb 2013 after 3 months developed scar tissue 
 First Re appt was September 2013 OOP for everything minus meds  
DH's TESE surgery December 2013
First cycle was February 2014 BFN none to freeze
 Second cycle was April 2014 BFP ending in Chemical Pregnancy none to freeze
 Third cycle June 2014 BFN none to freez
 Fourth cycle October 30th 28 retrieved, 13 mature and 12 fertilized
PICSI, assisted hatching and fresh sperm from my DH's TESE surgery used
5 FROZEN from a freeze all cycle! 
FET completed on DECEMBER 9TH!!!
Beta #1 13dp5dt BFP!! 800
Beta #2 15dp5dt 2100
Beta #3 17dp5dt 3600 
First Scan January 5th! Everything looks great! Heart rate of 121!
Second Scan January 20th. Baby Justone13 looks amazing. Heart rate of 175!
Baby Girl is due August 27th
Liv Annmarie born 8/25 7lbs 6oz 21 1/2 inches long 
image 

Re: Extremely High E2 Level OHSS Q

  • @MeatandBandP‌ I've heard of taking cabergoline or letrozole. But when I mentioned these to my re he wasn't interested in putting me on them. I guess he isn't thrilled with the studies that they have been through.
    SIGGY WARNING//TICKER WARNING//PAIF

    Long of the Short:
     TTC since April 2013  DH 42 y/o I'm 30  Dh had vasectomy reversal Feb 2013 after 3 months developed scar tissue 
     First Re appt was September 2013 OOP for everything minus meds  
    DH's TESE surgery December 2013
    First cycle was February 2014 BFN none to freeze
     Second cycle was April 2014 BFP ending in Chemical Pregnancy none to freeze
     Third cycle June 2014 BFN none to freez
     Fourth cycle October 30th 28 retrieved, 13 mature and 12 fertilized
    PICSI, assisted hatching and fresh sperm from my DH's TESE surgery used
    5 FROZEN from a freeze all cycle! 
    FET completed on DECEMBER 9TH!!!
    Beta #1 13dp5dt BFP!! 800
    Beta #2 15dp5dt 2100
    Beta #3 17dp5dt 3600 
    First Scan January 5th! Everything looks great! Heart rate of 121!
    Second Scan January 20th. Baby Justone13 looks amazing. Heart rate of 175!
    Baby Girl is due August 27th
    Liv Annmarie born 8/25 7lbs 6oz 21 1/2 inches long 
    image 

  • ******************** siggy warning ****************






    Yes, I did have high E2. Mine was over 4500 the morning I did the trigger. They debated switching me to a Lupron trigger, but finally we just decided to go with the Novarel hcg. The morning after the trigger it was over 6000. I started cabergoline the day of our ER and was very careful about diet - I ate a lot of protein and I drank as much gatorade and coconut water as possible. I had no issues with the cabergoline or OHSS even though I went ahead with the fresh transfer and it was successful. I did have giant cystic ovaries for a few months though.

    Good luck! I hope you don't run into any problems!
    ******************************************** siggy warning ******************************************

    image image

    image

    Married July 2011 * TTC #1 since 8/12 * Me: 29 DH: 29
    21 Cycles TI: BFNs
    DX: Stage 2 Endo, uterine polyps and paratubal cysts removed
    2/14: IVF #1 Lupron Protocol = 12R/10M/9F, no frosties; transferred one 3BB blast = BFN
    4/14: IVF #2 Antagonist Protocol = 18R/16M/15F/6 frosties; transferred one 4BB blast = BFP!!
    Beta #1 (5/12) = 232 Beta #2 (5/16) = 886 Beta #3 (5/20) = 3168
    EDD 1/18/15 It's a BOY 

    ~~~~~~ All Are Welcome ~~~~~~

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  • @Milagros315‌ thank you!! Do you remember what your cabergoline dosage was?
    SIGGY WARNING//TICKER WARNING//PAIF

    Long of the Short:
     TTC since April 2013  DH 42 y/o I'm 30  Dh had vasectomy reversal Feb 2013 after 3 months developed scar tissue 
     First Re appt was September 2013 OOP for everything minus meds  
    DH's TESE surgery December 2013
    First cycle was February 2014 BFN none to freeze
     Second cycle was April 2014 BFP ending in Chemical Pregnancy none to freeze
     Third cycle June 2014 BFN none to freez
     Fourth cycle October 30th 28 retrieved, 13 mature and 12 fertilized
    PICSI, assisted hatching and fresh sperm from my DH's TESE surgery used
    5 FROZEN from a freeze all cycle! 
    FET completed on DECEMBER 9TH!!!
    Beta #1 13dp5dt BFP!! 800
    Beta #2 15dp5dt 2100
    Beta #3 17dp5dt 3600 
    First Scan January 5th! Everything looks great! Heart rate of 121!
    Second Scan January 20th. Baby Justone13 looks amazing. Heart rate of 175!
    Baby Girl is due August 27th
    Liv Annmarie born 8/25 7lbs 6oz 21 1/2 inches long 
    image 

  • I also had super high e2 (7000). I had some vegetable cocktail juice after ER and no OHSS

    Official diagnosis: Unexplained IF. I am 32. I have low ovarian reserve (low AMH), and poor egg quality. I've also been diagnosed with mild glandular developmental arrest (lining problems, detected with EFT).

    We are using open ID donor sperm. IUIs #1-7=BFN. IVF September 2014 antagonist protocol, 8R,5M,3F, 5 day transfer of 1 morula = BFN. IVF#2 planned for January 2015 (antagonist protocol + HGH).

    Image and video hosting by TinyPic image

  • @kaly75‌ @emmuffy‌ thank you so much ladies. My re had me seriously scared when he said he's never had an E2 level that high. I'm like uh....great!!! FML! You all have put my fears to rest.
    SIGGY WARNING//TICKER WARNING//PAIF

    Long of the Short:
     TTC since April 2013  DH 42 y/o I'm 30  Dh had vasectomy reversal Feb 2013 after 3 months developed scar tissue 
     First Re appt was September 2013 OOP for everything minus meds  
    DH's TESE surgery December 2013
    First cycle was February 2014 BFN none to freeze
     Second cycle was April 2014 BFP ending in Chemical Pregnancy none to freeze
     Third cycle June 2014 BFN none to freez
     Fourth cycle October 30th 28 retrieved, 13 mature and 12 fertilized
    PICSI, assisted hatching and fresh sperm from my DH's TESE surgery used
    5 FROZEN from a freeze all cycle! 
    FET completed on DECEMBER 9TH!!!
    Beta #1 13dp5dt BFP!! 800
    Beta #2 15dp5dt 2100
    Beta #3 17dp5dt 3600 
    First Scan January 5th! Everything looks great! Heart rate of 121!
    Second Scan January 20th. Baby Justone13 looks amazing. Heart rate of 175!
    Baby Girl is due August 27th
    Liv Annmarie born 8/25 7lbs 6oz 21 1/2 inches long 
    image 

  • Justone13 said:

    @Milagros315‌ thank you!! Do you remember what your cabergoline dosage was?

    No, I'm sorry I don't remember. I think it was just one pill a day and I took it for 10 days, but I don't remember the value of each pill. As far as I know, it was just the standard dosage that doctors prescribe.
    ******************************************** siggy warning ******************************************

    image image

    image

    Married July 2011 * TTC #1 since 8/12 * Me: 29 DH: 29
    21 Cycles TI: BFNs
    DX: Stage 2 Endo, uterine polyps and paratubal cysts removed
    2/14: IVF #1 Lupron Protocol = 12R/10M/9F, no frosties; transferred one 3BB blast = BFN
    4/14: IVF #2 Antagonist Protocol = 18R/16M/15F/6 frosties; transferred one 4BB blast = BFP!!
    Beta #1 (5/12) = 232 Beta #2 (5/16) = 886 Beta #3 (5/20) = 3168
    EDD 1/18/15 It's a BOY 

    ~~~~~~ All Are Welcome ~~~~~~

  • Justone13 said:

    @Milagros315‌ thank you!! Do you remember what your cabergoline dosage was?

    No, I'm sorry I don't remember. I think it was just one pill a day and I took it for 10 days, but I don't remember the value of each pill. As far as I know, it was just the standard dosage that doctors prescribe.
    I haven't taken it yet because I haven't even started my cycle yet, but my doctor ordered some for me with my other meds and it says 0.5mg/day.

    I actually take it already for elevated prolactin. The standard starting dose for that is 0.25mg twice a week, just for comparison.
    **siggy warning**  **everyone welcome**

    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    DS- 11.07.02
    DSS- 6.26.04
    Married- 6.29.13
    TTC Again- Sept. 2013
    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    Test Results/Diagnosis- HSG & SA totally normal
    DX: 3/2014 Prolactinoma/Hyperprolactinemia- Started cabergoline 2/2014
    5/2014 Possible mild PCOS in addition to hyperprolactinemia??
    7/2014 Adding probable tubal factor to the diagnosis list
    9/2014 And now adding hypothyroid to the list- Started synthroid 9/2014
    Cycles 1-4 - Sept.-March- All Anovulatory 
    IUI #1 March/April-  Clomid 50mg + Clomid 100mg +Trigger + IUI #1 = BFN
     IUI #2 April/May-Clomid 100mg + Clomid 150mg + Trigger + IUI #2 + Endometrin=BFN
    IUI #3- June- Follistim 75iu + Trigger + IUI #3  Benched due to a 40 mm cyst. :-(
    IUI #3- July- Follistim 75iu + Trigger + IUI #3 + Endometrin = BFP! on 7/25/14
    Slowly rising betas - Ectopic suspected on 8/8/14 & confirmed on 8/11/14
    Methotrexate on 8/12/14 -HCG negative on 9/2/14
    IVF #1- November- Antagonist protocol: 11/1: start stims, 200iu of Follistim; 11/12 ER 17R/14M/14F; 11/17 5 day transfer of two blasts, 2 blasts and 2 expanding morulas frozen; 11/22 BFP!! (On FRER at 5dp5dt)
    Betas: 9dp5dt 205, 11dp5dt 497, 14dp5dt 1,709
    u/s at 5w0d- 1 sac; u/s at 6w0d 1 baby with heartbeat, another sac without a heartbeat
    image


  • I had an E2 over 6000 at ER for IVF # 1 and did not get OHSS.  I drank a lot of gatorade and took it easy.  Fx for you!
                        imageimage

                    image  imageimage
                      imageimage
      

    TTC #1 since November 2011
    Dx: Unexplained Infertility, probable endometriosis
    Feb-April 2013: Femara + TI: BFN
    May - September 2013:  Follistim + Ovidrel + IUI#1-4 = BFN
    IVF # 1 November 2013: transferred 1 perfect blast = BFN
    IVF # 2 April 2014: Endo scrape, transferred 2 blasts = BFP!! (first ever!), CP
    FET #1 June 2014: transferred 2 blasts = BFFN
    New Dx: Repeat Implantation Failure
     IVF # 3 November 2014 = BFP!!  Beta #1 9dp5t 272  Beta # 2 11dp5dt 626
    It's Twins! 
    *everyone welcome*
  • @shelbeans82‌ thanks!! So far so good!
    SIGGY WARNING//TICKER WARNING//PAIF

    Long of the Short:
     TTC since April 2013  DH 42 y/o I'm 30  Dh had vasectomy reversal Feb 2013 after 3 months developed scar tissue 
     First Re appt was September 2013 OOP for everything minus meds  
    DH's TESE surgery December 2013
    First cycle was February 2014 BFN none to freeze
     Second cycle was April 2014 BFP ending in Chemical Pregnancy none to freeze
     Third cycle June 2014 BFN none to freez
     Fourth cycle October 30th 28 retrieved, 13 mature and 12 fertilized
    PICSI, assisted hatching and fresh sperm from my DH's TESE surgery used
    5 FROZEN from a freeze all cycle! 
    FET completed on DECEMBER 9TH!!!
    Beta #1 13dp5dt BFP!! 800
    Beta #2 15dp5dt 2100
    Beta #3 17dp5dt 3600 
    First Scan January 5th! Everything looks great! Heart rate of 121!
    Second Scan January 20th. Baby Justone13 looks amazing. Heart rate of 175!
    Baby Girl is due August 27th
    Liv Annmarie born 8/25 7lbs 6oz 21 1/2 inches long 
    image 

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