Third-Party Reproduction

What does this mean? (day 2 fert report)

edited September 2014 in Third-Party Reproduction
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Re: What does this mean? (day 2 fert report)

  • mm29mm29 member
    edited September 2014

    (((Huge Hugs))

    There are three factors that play a role in embryo development: Egg, sperm, and the lab.

    I'm not an expert by any means, but my understanding is that MFI manifests in an embryo after day 3, so I'm not sure if this a sperm issue. Is your donor proven? Can you ask about the quality of embryos of the other egg recipient?

    I know embryos can repair themselves by day 5! I hope this is the case for you! You are still in this! Sending lots of positive vibes to your embies. Hang in there sweetie!!

    ::: Married June 2003:::
    TTC #1 since: Aug. 2008
    Me: 34, DOR, MTHFR-A1298C (heterozygous), decreased blood flow to uterus, Mild Endo
    DH: 38, Balanced translocation 5&10, unexplained MFI, normal SA and SCSA
    Tx History: IUI 1&2= BFN
    IVF# 1 W/ICSI= BFN
    IVF# 2: cancelled d/t no response
    IVF# 3= 1 egg retrieved=immature/not viable
    IVF# 4= c/p
    ***CCRM ODWU***
    Found DHs BT and Me-decreased blood flow to uterus
    Recommended DE IVF w/PGD, incorporate electro-acupuncture. Decided to cycle locally
    ***New RE***
    DE IVF# 1(cycle #6) w/pgd, (freeze all): 30R, 23M, 15F, slow/poor embryo development, 4 biopsied, 1 Normal "Norm"; DE IVF w/PGD, incorporate electro-acupuncture. 
    IVF# 6: (OE/DS) cancelled
    IVF# 7: (OE/DS) 1R, 1M, 1F, arrested day 5
    Plan-DE IVF# 2 (cycle #8): DE/DS in May 2015


    http://icanhazbabyz.blogspot.com/
    imageimage image 
  • I am very sorry. Hoping you get answers asap. Wish I had some insight ((hugs))

    My heart is as open as the sky.
    Read about it on the blog

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    2 Corinthians 12:9 But he said to me, "My grace is sufficient for you, for my power is made perfect in weakness." Therefore I will boast all the more gladly about my weaknesses, so that Christ's power may rest on me.


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  • We never got any info until day 5, so I can't compare. 
    In fact, our embryologist said that they found that information at random time points wasn't very useful so the clinic quit doing it about three years ago.

    What I can tell you is that my sister transferred two crappy embies on Day 3 and my niece was born from the transfer.

    Are they planning on transferring embies on day 3?

    I am so sorry about how you are feeling right now. Unfortunately, there is nothing to do but wait.
    (((hugs))) and we are here supporting you.
    TTC #1 since 12/2010 DH: MFI, cancer survivor Me: Resected septate uterus, lap treated mild endo, tubes open, ovulate on own, autoimmune disease 3 Failed IUI's (2/2012, 4/2012, 6/2012) 
    IVF #1 August 2012. BFP! Beta #1 56.7 Beta #2 150 One baby, one heartbeat on 9/20/12! no h/b @7w6d. dandc @8w0d
    FET #1 December 2012, BFN
    FET #2 February 2013, no embies survived thaw
    IVF #2, BFP #2, Loss #2 March 2013, Scar tissue discovered, RPL testing,
    IVF #3, BFP #3, Loss #3 (twins) September 2013
    Hostile ute, moving onto Gestational Carrier!

    GC/FET #1 of 1 5AA blast and 1 compacted blast, February 2014, BFP #4 on 3/1/2014!
    6w u/s 1 bean with h/b of 145 bpm, 8w u/s 187 bpm
    EDD 11/7/14. Please, please, please stick little one!

    Praying unceasingly for a miracle. ALL welcome!

    image










  • I also cannot offer anything useful. I'm so sorry you are going through this. Hopefully the doctor will call you soon and be able to answer questions and alleviate your concerns. *HUGS* 

    TTC since April 2010
    BFP #1 – March 2011, missed m/c April 2011
    BFP #2 – October 2011, m/c November 2011
    Surprise BFP #3 – December 2011, diagnosed as cornual, terminated January 2012
    BFP #4 – June 2012, m/c July 2012
    Diagnosed with bicornuate ute and MTHR gene mutation
    BFP #5 – October 2012, missed m/c November 2012
    BFP #6 – January 2013, m/c March 2013
    No longer TTC. Diagnosis: Hostile ute. Heartbroken and bitter. Pursuing surrogacy.
    June 2013 - Carrier found! Could this really happen?!
    image
    ~All AL always welcome~

  • I agree with what MM29 said and had a few more comments. First off, I've never gotten a day 2 report so I don't know that you will be able to compare with others since we never knew how they looked on day 2. I did, however, do 2 2dt with my OEs bc we only had 2 embryos so it didn't make sense to wait. I always had 2 cells or 1 cells. I "think" I might have had one 4 cell the first time but it was 3 yrs ago so memory is fading. I know you are upset and understandably but you have to wait to see what they will do. All is not lost at this stage!!! Unfortunately not all donors have good eggs. It happens and everyone is always blindsided when it happens. Lord knows I was totally shocked when I walked in to my first DE transfer to find out we had crap!!! It sucks and nothing can prepare you for it. DE is NOT the given that the doctors purport it to be. That said, one of my twins was only 4 cells "grade c" (so fragmented) on day 3!!! But she survived to blast on day 6 and is a normal XX female! So please don't give up yet. Questions I'd ask: how long did the donor stim for? Too long or too short can be an issue. Ask for her estrogen levels along the way-- did they coast her at all? Not sure if you will get an honest answer but this is what happened with my first donor and why I believe her eggs were fried: the clinic doesn't do retrievals on Sunday so they checked her Friday morning and told her to trigger on Sat night for a Monday retrieval. I think that extra day fried the eggs. I found out after the fact that she also developed bad OHSS and was hospitalized. Ask if there were any stim complications.

    Hang in there.

    TTC #1 since 8/1/10; Me:41 and BRCA1+, DH:46
    DOR (FSH 24.3)/ terrible egg quality ; homozygous MTHFR c677t
    5 IUI's: 2/11 to 6/11 and 1/12= BFN
    OE IVF#1-4 8/11-6/12= all BFN
    DE IVF#1 11/12 bad embryos= BFN
    DE IVF #2 2/13 BFP/Beta hell: m/c 5w6d
    CFNBC 7 months, not doing well; decided on guarantee program at RBA w/frozen DE
    DE IVF #3 1/14  ET 4BB; BFP;M/C 5w1d, incomplete m/c; MVA extraction in ER 7w1d

    DE FET#1 ET 3/1714; BFP, beta 1 3/27= 197, beta 2 3/31= 1586, beta 3 4/7= 13879!!
    First u/s= Twins with HBs at 6w2d! We are Team Pink x 2!!

    K & K born 11/21/14 at 38wks 4 days

    imageimage

    SAIF/PAIF Welcome


    http://waitingforraintostop.wordpress.com

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  • Sending big hugs at this difficult time. I'm glad that you were able to talk to your doctor & hope that it works out for you. Keep us posted!!
    **SIGGY WARNING**

    Me: 32 DH: 35  TTC#1 since March 2012
    Dx: Poor Embryo Quality, Arcuate Uterus, Poor Uterine Blood Flow, Mild Endo, 
           Protein S Deficiency, Sjorgen's Syndrome 

    IUI #1-5: BFN
    Laparoscopy & Hysteroscopy: minimal endo, partial septoplasty
    IVF #1: 10R/6M/6F ~ Day 3 ET = BFN
    IVF #2: 14R/9M/5F ~ transfer canceled ~ all embryos arrested at 1-2 cell stage
    IVF #3: 9R/5M/5F ~ 1 frosty!
    IVF #4 (FET #1): BFN

    IVF #5 (DE IVF #1 with Dr. KK protocol): Currently PREGNANT!!!!!!
    Synthroid + Prednisone + Metformin + Baby Aspirin + Supplements Galore = 15+ pills a day
    Lupron + Lovenox + Delestrogen + IVIG + B/W = 2-5 pokes a day
    19R, 17M, 17F - transferred two Grade A blasts 11/16, four frosties!!!
    Beta #1 11/24 (13dpo/8dp5dt) = 367 ~ Beta #2 11/26 (15dpo/10dp5dt) = 709
    Beta #3 11/29 (18dpo/13dp5dt) = 1,997 ~ Beta #4 12/1 (20dpo/15dp5dt) = 3,403

    imageimageimage

    My Blog: Running and Dreaming for Two ~ All are Welcome!
  • I just wanted to add that I had a cycle once where all of my embryos had fragmentation on day three an no fragmentation on day five, granted they still didn't work out but my point is that things can still change, hang in there.

     


    imageimageimageimage

     
     

    *******siggy/ticker warning***** 

     Me(31). DH (31)

    DH SA normal count and motility, 1% morphology
    Me .72 AMH, Fragile X premutation carrier
    IVF #1 (6/12/13) BFN

    IVF #2 (8/16/13) BFN

    FET 10/4/13 Chemical

    IVF #3 MC 5 weeks 5 days

    IVF #4 DE 11/7 BFP, edd 7/28/15

    All Welcome

    BabyFruit Ticker

  • Huge hugs! I've never had a 2 day fertilization report, but am hoping things turn out for you... It is such a hard process.. Know that you have support here!
    DS#1 born 9/23/06 
    Twins DS#2 and 3 born at 31 weeks, 3 days due to a short cervix on 8/2/13.
  • BeckyP005BeckyP005 member
    edited September 2014
    Just wanted to send you big giant hugs. FX everything turns out!

    ME:46 MH:44 DE IVF 2014
    Met with RE 4/11. 2 IUI's BFN. DE best option. Switched clinics to do "shared" program. Had to retake all tests and a mamm that put me behind and then on a DE waiting list for 12 months. Picked a donor!! (10/13/13) Got matched. Estimated transfer in December. After 2.5 years of patiently waiting I will finally cycle....can hardly believe it. DE cycle got cancelled. One of her tests came back positive.  Waiting for another donor. Donor picked!! (1/18/14)

    DE IVF #1 (4/26) BFN  DE FET #1 (6/4) BFP! Beta 1=339 Beta 2=852 Beta 3=9957 EDD 2/22/15!!


     

     

         imageimage 
         image   imageimage



  • The user and all related content has been deleted.
  • So sorry this is so tough. Just remember, it only takes one.

    image
    DOR and AMA
    2/12-5/12: 4 IUI cycles = all BFN;
    7/12: DE IVF # 1 (with ICSI)- 20R, 16M, 14F, 5DT of 2 blasts; 6 frosties = BFN;
    Lupus anticoagulant initially high, then found to be normal on hematology consult;
    Follow up testing in September all clear;
    Started synthroid for "high normal" TSH;
    FET # 1- late October 2012- BFP on FRER; beta # 1- 21(low), beta # 2- 48 (still low), beta # 3- 132, beta # 4- 1,293; beta # 5- 5,606; last beta- over 100,000. First u/s 11/21- heard heartbeat
    12/12- Officially an OB patient!
    Level 2 ultrasound at 20 weeks shows vasa previa and VCI
    Referral to MFM and mandatory c section for delivery
    Beautiful baby girl born at 34 weeks
    Finally home after 15 day NICU stay!
    Trying for sibling: FET # 2- May 2014; beta 5/31, BFN
    FET #3, early July 2014; beta 7/14, BFN
    DE IVF # 2- August 2014; 14R, 13M, 11F, 5dt of 2 blasts (3 AA), 5 frosties = BFN
    FET #4- December 2014, yet another BFN

    Dr. KK work up shows borderline uterine blood flow, elevated NK cells, and MTHFR mutation (homozygous for c677t)

    Added baby aspirin, prednisone, supplements, Metanx, and intralipids

    Switched to large clinic for final attempt; had endometrial receptivity testing in January; FET March 2015 = yet another BFN

    Likely OAD- NBC

  • I also don't have any experience with a 2 day report.  I'm thinking really good thoughts for you though!

    TTC #1 since May 2010

    OE IVF #1  9/2/13 Cancelled- poor response

    DE IVF #1 3/12/14- BFP 3/17/14- ectopic, right tube removed 4/11/14 @ 7 weeks

    DE FET #1 7/3/14-Transferred 2 5AA 6 day embryos Beta 7/13/14 BFN

    DE FET #2 9/5/14-Transferred 2 4BB 5 day embryos Beta 9/15/14 BFN

    DE FET #3 in December- Cancelled, didn't respond to meds

    DE FET #3 (2nd try) 2/13/15- Transferred 1 4BB and 1 4BA 5 day embryos Beta 2/23/15  BFN again (CP)

    DE FET #4 - last 2 frosties....5/22/15- Transferred 1 4BA embryo...only one frostie thawed properly.  Beta scheduled for 6/1-  BFN (beta 2, 2.81, 6, 23, 49.4) 6/15/15 Discovered ectopic in left tube.  Methotrexate given. Moving on to a new donor. Hoping to transfer by the end of the year.

    Cant find a donor that is healthy and available.  Looking at being happy with just the two of us.

     

  • Thinking of you and sending hugs.
  • The user and all related content has been deleted.
  • ((hugs)) FX those two are your rock star embies!

    ***signature & ticker warning***


    Me: 30 ~ Stage IV Endo ~ AMH .38 ~ AFC 8
    AMH .97 as of 4/2012! ~ AMH 1.63 as of 4/2013!?!

    Him: 29 ~ perfect swimmers

    Laparotomy w/partial oophorectomy 8/2009 to remove cysts/endo.
    Stopped BCP 4/2010.
    Multiple clomid rounds from 11/2010 to 6/2011. ~ All BFN
    IUI w/clomid 7/2011. IUI w/clomid & injectables 11/2011 & 1/2012. ~ All BFN

    IVF:EPP 5/2012 ~ (4R, 3M, 2F w/ICSI). Both embryos txfrd. ~ BFN
    BCP to manage endo from 10/2012 to 12/2012.
    FET w/donor embryos #1: 10/2013 Cancelled
    FET w/donor embryos #1.2: 11/2013
    ~ ET of 2 beautiful blasts on 11/27.
    Beta 1: 503(12dp5dt) Beta 2: 1035(14dpt) Beta 3: 3001(16dpt)
    Beta 4: 8503(19dpt)
    Twins with an EDD of 8/15/14! Team Purple
    G&B born 6/30/14 at 33w3d via emergency c/s.


    If you're wondering about my avatar...it's a fried pickle chip shaped like a fetus!


    image

    image
  • ::lurking::

    ((hugs)) Don't give up yet a lot can change from day 3 to day 5. My embryos have always been super crappy quality on day 3, but we have had some top grade blasts. We haven't had a successful cycle, but I don't know how much is because of embryo quality and how much is from immune issues. Good luck, I have my FX for you!

    imageimageimageimageimage

     

    image

    TTC #1 since August 2011

    My Blog

    September 2012: Start IF testing

    DH (32): SA is ok, slightly low morph, normal SCSA  Me (32): Slightly low progesterone, hostile CM, carrier for CF, Moderately high NKC, High TNFa, heterozyogous mutated Factor XIII, and +APA

    October 2012-May 2014: 4 failed IUIs, 3 failed IVFs, and 1 failed FETw/donor embryos

    November 2014: IVF w/ICSI #4 Agonist/Antagonist with EPP and Prednisone, Baby Aspirin, Lovenox, and IVIG for immune issues.  Converted to freeze all due to lining issues.  2 blasts frozen on day 6!

    January 2015: FET #2 Cancelled due to lining issues

    April 2015: FET #2.1


    PAIF/SAIF Welcome!

  • Hang in there @JimBobCooter‌ !!! Sending positive vibes in your direction!
    **SIGGY WARNING**

    Me: 32 DH: 35  TTC#1 since March 2012
    Dx: Poor Embryo Quality, Arcuate Uterus, Poor Uterine Blood Flow, Mild Endo, 
           Protein S Deficiency, Sjorgen's Syndrome 

    IUI #1-5: BFN
    Laparoscopy & Hysteroscopy: minimal endo, partial septoplasty
    IVF #1: 10R/6M/6F ~ Day 3 ET = BFN
    IVF #2: 14R/9M/5F ~ transfer canceled ~ all embryos arrested at 1-2 cell stage
    IVF #3: 9R/5M/5F ~ 1 frosty!
    IVF #4 (FET #1): BFN

    IVF #5 (DE IVF #1 with Dr. KK protocol): Currently PREGNANT!!!!!!
    Synthroid + Prednisone + Metformin + Baby Aspirin + Supplements Galore = 15+ pills a day
    Lupron + Lovenox + Delestrogen + IVIG + B/W = 2-5 pokes a day
    19R, 17M, 17F - transferred two Grade A blasts 11/16, four frosties!!!
    Beta #1 11/24 (13dpo/8dp5dt) = 367 ~ Beta #2 11/26 (15dpo/10dp5dt) = 709
    Beta #3 11/29 (18dpo/13dp5dt) = 1,997 ~ Beta #4 12/1 (20dpo/15dp5dt) = 3,403

    imageimageimage

    My Blog: Running and Dreaming for Two ~ All are Welcome!
  • Sending lots of positive vibes your way!!  

    ::: Married June 2003:::
    TTC #1 since: Aug. 2008
    Me: 34, DOR, MTHFR-A1298C (heterozygous), decreased blood flow to uterus, Mild Endo
    DH: 38, Balanced translocation 5&10, unexplained MFI, normal SA and SCSA
    Tx History: IUI 1&2= BFN
    IVF# 1 W/ICSI= BFN
    IVF# 2: cancelled d/t no response
    IVF# 3= 1 egg retrieved=immature/not viable
    IVF# 4= c/p
    ***CCRM ODWU***
    Found DHs BT and Me-decreased blood flow to uterus
    Recommended DE IVF w/PGD, incorporate electro-acupuncture. Decided to cycle locally
    ***New RE***
    DE IVF# 1(cycle #6) w/pgd, (freeze all): 30R, 23M, 15F, slow/poor embryo development, 4 biopsied, 1 Normal "Norm"; DE IVF w/PGD, incorporate electro-acupuncture. 
    IVF# 6: (OE/DS) cancelled
    IVF# 7: (OE/DS) 1R, 1M, 1F, arrested day 5
    Plan-DE IVF# 2 (cycle #8): DE/DS in May 2015


    http://icanhazbabyz.blogspot.com/
    imageimage image 
  • Day 3 pseudo update:  I haven't talked to the doctor yet but our nurse did email me and say that apparently two of them grew pretty well overnight and that we will still be transferring on Saturday.  The doctor will call me after she's done with her surgeries to give us the details.   Still not going to let myself be excited after this scare but at least it's still going forward.
    YAY!!

    My heart is as open as the sky.
    Read about it on the blog

    Image and video hosting by TinyPic



    2 Corinthians 12:9 But he said to me, "My grace is sufficient for you, for my power is made perfect in weakness." Therefore I will boast all the more gladly about my weaknesses, so that Christ's power may rest on me.


    Follow Me on Pinterest
    BabyFruit Ticker
  • Mrs.McIrishMrs.McIrish member
    edited September 2014
    Glad things look much better. I think this is why a lot of clinics do not provide any data on the embryos during the process bc it can change and cause a lot of anxiety. My DE clinic doesn't even give day 3 info-- it's fert and then wait for day 5. (I did get some info on day 4 when I was at the clinic bc I was freaking out with PTSD after two prior bad rounds of DE). Sending T&Ps your way!

    TTC #1 since 8/1/10; Me:41 and BRCA1+, DH:46
    DOR (FSH 24.3)/ terrible egg quality ; homozygous MTHFR c677t
    5 IUI's: 2/11 to 6/11 and 1/12= BFN
    OE IVF#1-4 8/11-6/12= all BFN
    DE IVF#1 11/12 bad embryos= BFN
    DE IVF #2 2/13 BFP/Beta hell: m/c 5w6d
    CFNBC 7 months, not doing well; decided on guarantee program at RBA w/frozen DE
    DE IVF #3 1/14  ET 4BB; BFP;M/C 5w1d, incomplete m/c; MVA extraction in ER 7w1d

    DE FET#1 ET 3/1714; BFP, beta 1 3/27= 197, beta 2 3/31= 1586, beta 3 4/7= 13879!!
    First u/s= Twins with HBs at 6w2d! We are Team Pink x 2!!

    K & K born 11/21/14 at 38wks 4 days

    imageimage

    SAIF/PAIF Welcome


    http://waitingforraintostop.wordpress.com

  • So happy that things are looking more positive! It is important to remember that
    1) We don't know everything about embryology. If we did, we would always pick winners
    2) Most processes in life aren't linear. Things start and stop and curve and...well, you know


    The roller coaster is so tough. Do what you can to relax before transfer (I think a massage or at least mani/pedi) is in order after all that you have gone through this week!

    TTC #1 since 12/2010 DH: MFI, cancer survivor Me: Resected septate uterus, lap treated mild endo, tubes open, ovulate on own, autoimmune disease 3 Failed IUI's (2/2012, 4/2012, 6/2012) 
    IVF #1 August 2012. BFP! Beta #1 56.7 Beta #2 150 One baby, one heartbeat on 9/20/12! no h/b @7w6d. dandc @8w0d
    FET #1 December 2012, BFN
    FET #2 February 2013, no embies survived thaw
    IVF #2, BFP #2, Loss #2 March 2013, Scar tissue discovered, RPL testing,
    IVF #3, BFP #3, Loss #3 (twins) September 2013
    Hostile ute, moving onto Gestational Carrier!

    GC/FET #1 of 1 5AA blast and 1 compacted blast, February 2014, BFP #4 on 3/1/2014!
    6w u/s 1 bean with h/b of 145 bpm, 8w u/s 187 bpm
    EDD 11/7/14. Please, please, please stick little one!

    Praying unceasingly for a miracle. ALL welcome!

    image










  • I'm so pleased to hear that things are looking better. Wishing you all the best at your transfer tomorrow!
    TTC with DOR, low morphology, fertilization issues
    IVF#1 Oct 2009 (CCRM) - BFN
    IVF#2 March 2010 - Poor response/cancelled
    DE IVF#1 Aug 2010 - BFN
    DE IVF#2 Dec 2010 - Transferred 1, 2 frozen - BFP!
    TTC#2 FET Jan 2013 - Transferred 1 - BFP!

    Baby Birthday Ticker Ticker Baby Birthday Ticker Ticker
  • Yay!! And for the record, just finished feeding my BC embie take home baby!!! So glad things ate looking good! Hope transfer went great!
    Lil'mamaz was born on Aug 21, 2014! She's PERFECT!

    It's been a long road to here...
    Me (43) and J (45) - same sex couple. And we don't feel 40+!
    June'12 - First RE Visit
    Sept. '12 - Tubes removed
    Dec. '12 - Donor Egg/Donor Sperm IVF Cycle - 4 good embies!
    Dec. '12 - Fresh transfer, BFP! EDD 8/29/13
    Mar. '13 - Missed m/c at 16w1d, baby boy stopped growing at 15w4d
    Loss due to umbilical cord clot...baby was perfect. :(
    Jul '13 - FET#1 - c/p
    Sept. '13 - FET#2 - BFN
    Dec.' 2, 2013 - FET#3 with our last chance embie - BFP!!!
    Dec' 26, 2013 - hb!!
    EDD 8/20/14 with a baby girl!
    Little S was born on 8/21/14 - 8lb, 14 oz and 20 inches long.
    We live in Seattle and used SRM for our donor egg IVF cycle


    imageimageimageimage

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  • Hooray!!  Continued thoughts for your little fighters!! 
    ::: Married June 2003:::
    TTC #1 since: Aug. 2008
    Me: 34, DOR, MTHFR-A1298C (heterozygous), decreased blood flow to uterus, Mild Endo
    DH: 38, Balanced translocation 5&10, unexplained MFI, normal SA and SCSA
    Tx History: IUI 1&2= BFN
    IVF# 1 W/ICSI= BFN
    IVF# 2: cancelled d/t no response
    IVF# 3= 1 egg retrieved=immature/not viable
    IVF# 4= c/p
    ***CCRM ODWU***
    Found DHs BT and Me-decreased blood flow to uterus
    Recommended DE IVF w/PGD, incorporate electro-acupuncture. Decided to cycle locally
    ***New RE***
    DE IVF# 1(cycle #6) w/pgd, (freeze all): 30R, 23M, 15F, slow/poor embryo development, 4 biopsied, 1 Normal "Norm"; DE IVF w/PGD, incorporate electro-acupuncture. 
    IVF# 6: (OE/DS) cancelled
    IVF# 7: (OE/DS) 1R, 1M, 1F, arrested day 5
    Plan-DE IVF# 2 (cycle #8): DE/DS in May 2015


    http://icanhazbabyz.blogspot.com/
    imageimage image 
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