Trouble TTC

1 iui vs 2 iui's

Hey ladies. Quick question. What's your thought when it comes to b2b iui's?? Since we are OOP for the IUI every penny for the procedure and meds counts for something. If I can get away with just doing one that would be awesome but I'm scared that if I don't do the second one I'll blame myself later. What does your dr think or say?
Me: 26 (IC/PCOS-2000mg of Metformin daily)

June 2014- HSG=clear

DH: 27 (SA results were great minus the slightly low morphology)
Started dating DH in 2002 at 14 years old
Married on 03.01.2014
Officially TTC since April 2014 
January 2013- Surprise BFP, m/c at 6 weeks, D&C 2 Weeks later
April 2014- First RE appointment
July 2014- IUI#1-Canx due to scar tissue and polyps. TI with the help of Ovidrel. BFN

August 2014- Hysteroscopy to remove scar tissue and polyp

September 2014- IUI #1.1-100mg Clomid, Ovideral, 11.5 million swimmers=BFP

EDD-6/3/15- Our sweet baby Ryan was born on 1/6/15 and is in the arms of an Angel

Dx with IC on 1/6/15



Re: 1 iui vs 2 iui's

  • My clinic recommends b2b because they believe it gives you the best chance of conceiving (their words, not mine).  With my first cycle the timing didn't work out for me to have b2b so we just did one and it was successful.  Many RE's seem to have different opinions on it.  We are out of pocket as well and this cycle we will be doing the b2b iui's (unless there is a last minute change), because our RE recommends it, but I don't know how much it really increases your chances. 

    Me (29): Hashimoto's, CD3/7DPO bloodwork & ultrasound normal, HSG & SHG(x2) all clear
    DH (29): SA Perfect
    TTC Since Jan '13, First RE Appt Jan '14
    DX: Unspecified Ovarian Dysfunction, Long Cycles
    May '13 BFP, C/P 4w3d
    Apr '14:  50mg clomid + ovidrel + B2B IUI #1=BFP,  Natural M/C 6.5wks
    Aug '14: 50mg clomid + ovidrel + B2B IUI #2=BFN
    Oct '14: 100mg clomid + ovidrel + IUI#3 =BFN
    Nov 14: 100mg clomid + ovidrel + B2B IUI#4=slow response, bad lining, cancelled
    FU with RE, more bloodwork: Anticardiolipin +
    Dec 14: 5mg Letrozole+baby aspirin +ovidrel + B2B IUI#4.1=BFFN
    Jan '15: 5mg Letrozole +baby aspirin + ovidrel +B2B IUI #5= BFP!! 
    Beta #1 210  Beta #2 546


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  • My RE said BTB IUIs don't really increase chances that much. I don't know how it can't. I know someone who had mild MFI and got pregnant with BTB. If I had the money, I would do the BTB, it can't hurt.


    TTC #1

    Me: AMA, DH: MFI

    Official DX - MFI due to Hemochromatosis

    IVF #1 Nov. 2014 - ER 11/10 (10R 6M 6F) - ET 11/13 

    3DT of 3 embies - no frosties - CP = BFFN!!!!

    ****All Welcome****

    imageimage



  • I have had b2b IUI for two cycles now, the first cycle on day 2 DH's levels weren't great but this second cycle they were almost as good as day 1. I will find out on Thursday if it worked or not. I suppose it's a personal opinion and if you are able to do it then you are slightly increasing your chances. Good luck!!

    Me (29), DH (38)

    Oct 2009   - Married
    Aug 2011   - Started TTC
    Jan 2012   - OB Referred to RE
    Feb 2012   - RE Visit #1
    Apr 2012   - HSG (Normal), PCOS - DH SA (low count and low motility)  
    June 2012   - Provera, Clomid, TI - BFN
    July 2012   - IUI #1, Provera, Clomid 50mg, Trigger Injection - BFN
    Aug 12 - Feb 14 - Break
    Feb 2014   - New OB referred to new RE
    Mar 2014   - New RE visit #1
    Apr 2014    - TSH  level elevated, need to retest.
    May 2014   - TSH retested, higher than 1st test. Start on Synthroid. DH SA (Normal)
    June 2014   - Start on DHEA, CO-Q10, New brand of Prenatals
    July 2014   - Cycle came on its own, b/w on CD2, TSH (normal), Femara CD3-CD7, CD14 - u/s + Ovidrel + baby aspirin regimen. IUI #1 B2B on CD15/16 - BFN

    August 2014 - u/s on CD3 normal, Femara CD3-CD7, u/s CD12, Ovidrel on CD13. IUI #2 B2B on CD 14/CD15 - BFN.

    September  2014 - u/s on CD3 normal, Femara CD3-CD7, u/s scheduled for CD12

    *** September 3T Siggy Challenge: Favorite Fall Shows ***

    image
  • I did 2 B2B IUIs that resulted in 2 BFN so I don't have anything great to say about B2B :)

    Me: 33, DH: 32

    TTC: 2 years
    Fertility blood tests all normal
    Tilted uterus
    3 day ultrasound 17 follicles
    HSG: 11/13/13- tubes open
    DH SA: SUPER sperm (145 million, 84% motility, 22% morphology)
    All infection disease and immunity blood tests NORMAL

    FIRST IUI May 2014: 100 mg Clomid days 5-9, third ultrasound CD 13 revealed four follicles 27, 24 and 20 and 13mm. Trigger shot May 28 with IUI May 29 and 30 (fingers crossed) - BFN started spotting 11DPO :(

    IUI #2 B2B 6/23 and 6/24, three mature eggs and 130 million sperm! FX this is the month!  BFN 7/8

    3rd cycle benched due to cysts - TI with OPK tests -  BFN

    3rd mediated cycle: Clomid+Trigger+TI  (three follies left side, one on right as usual....what the hell right ovary get it together and produce some damn follicles!) 7DPO progesterone level 43 with NO suppositories YAY for a natural strong ovulation. Beta canceled started spotting 13DPO - Third time is not a CHARM! 14 day cycle WTF! Everything looks normal - RE wants to start injectables next cycle so this cycle I'm benched

    Officially benched until March....but still plan on trying the baking soda douche due to my excessive and thick CM

    JANUARY SIGGY CHALLENGE...This is so me!

    image


    Love this man....he was so before his time in his thoughts and ideas about the world....been obsessed about him lately bringing it back to the early 90s.

    image

    Never thought I would like long hair....

    image

  • I just asked my RE about this a couple weeks ago because my sister in law did back to back IUIs all 6 times.  My RE doesn't believe it really increases your chances that much (I think they said 5%) and also he said that it is mainly used when sperm count is low.  So we decided against it. 
    Me (29), DH (32)
    Aug 2011  - Married
    Jan 2013   - Started TTC
    Jan 2014   - OB started some testing 
                         - HSG - Normal
                         - Ultrasound - Normal
                         - SA - Normal, but tested positive for Ureaplasma
                         - Both of us on antibiotics to treat ureaplasma
                         - Blood work - progesterone: 15.9, TSH: 0.89, FT4: 1.2, Prolactin: 33.4 
    Feb 2014   - Endometrial Biopsy - Normal
    Mar 2014   - Prolactin: 22.9, referred to RE
    Apr 2014   - First RE appointment, put on medication for high prolactin levels 
                      - Clomid (50 mg) 1 follicle, Trigger shot - BFN
                      - Second SA - All Normal, borderline morph (5%) 
    May 2014   - Clomid (100mg) 2 follicles, Trigger shot - BFN
                      - blood work: Estradiol: 32.7, FSH: 5.3, Prolactin: 14.1
    June 2014  - IUI #1, Clomid (150 mg), 3 follicles, Trigger shot - BFN 
    July 2014   - IUI #2, Clomid (150 mg), 4 follicles, Trigger shot - BFN
    Aug 2014   - IUI #3, Femara 2.5, 3 follicles, Trigger shot (first time done by DH!!) - BFN
                      - Hysteroscopy - Normal
    Sept 2014 - IUI #4 Femara 2.5, 1 follicle, possibility of another one, Trigger shot - BFN
                       -Progesterone test 4 DPIUI - 7.8...started crinone.
    Oct 2014 - IUI #5 Follistim 150 3 possibly 4 follicles - Trigger Shot - BFN
    Oct/Nov 2014 - Follistim 150 with TI & Trigger shot - ???

    **October Siggy Challenge**

    I don't even know what he is supposed to be!
    image


    **EVERYONE WELCOME!! :)**

  • My RE does not do back to back iui's. A girl that I work with goes to a different RE, and she asked if she could do b2b iui's. They told her that they would do it if she wanted to, but that there is no scientific evidence that it works better than 1 iui.

    imageimage

    TTC #1 January 2009
    January 2010 SA results: Count 16 million, Motility 40%, Morphology 2%
    January 2010- Surprise BFP! DS born 10/1/2010 :)
    January 2013 TTC #2
    September 2013 Repeat SA: Count= 1.7 million, Motility= 24%, Morphology= 2%
    November 6th 1st Appointment with RE: diagnosed with severe MFI
    Testing to try to determine a cause & possible treatment for MFI
    CD 3 blood work for me. RE does not want to repeat my HSG/lap at this point,
    but may want to before moving forward with any fertility treatments.
    After seeing the uro, DH is currently taking lots of supplements and clomid to try to boost his count. We will have a repeat SA in February to see if it works.
    Follow up SA numbers are: Count= 4 million, Motility= 40%, Morphology= 1%
    Uro wants us to have another follow up SA 5/9 to see if we see further improvement than we are back to the RE to make a game plan.

    SA 5/9/2014 Count: 12 Million, Motility: 60%, and Morphology 2%. We will be doing iui #1 in late June

    IUI #1 6/28 clomid + ovidrel, post wash count 3 million total sperm= BFN

    IUI # 2 7/21 clomid+ ovidrel. post wash count 900,000 total sperm= BFN

    IVF planned for early November- cancelled due to cyst

    December IVF #1- 22 eggs, 20 mature,16 fertilized

    12/9 Transferred 1 4AA Blast, 6 frosties


    *****Everyone is welcome******

  • Everything I've read says that B2B IUI barely increases chances (like, maybe a percentage point if that). B2B are done typically at 24hrs and 48 hrs, but research on single IUIs shows that the ideal time is 35hours. Especially since cost is a factor here, I would much prefer a single IUI at the ideal time. That said, if it wasn't working, I'd probably ask the RE if changing the timing or doing B2B might make a difference in my case.
    January 3T Siggy Challenge - New Year's Resolutions
    image
    imageimage

    Me (29), DH (30) TTC actively 54 55+ cycles | All BFNs
    MFI (low everything) | Endo Stage 1 & Stenotic Cervix (treated) | PCO
    Married - July 2008 | Started TTC - Jan 2009RE Visit #1 - Mar 2014 
    IUI #1 ICI #1 - June | IUI #1.1 Laparoscopy - Aug
    IUIs #1.2, 2, 3 - Sept, Oct, Nov (Letrozole) - BFNs 
    IUI #4 - Dec (Bravelle) | IUI #5 - Dec/Jan (Bravelle) - 5 follies + TI - BFNs
    IUI #5.1 - Jan (Bravelle) Cancelled 
    Planning to start IVF in March!
    ***All Welcome***
  • Thanks ladies. I guess I'll follow my RE lead. I'm such a worry wart that I may just do it to put my mind at ease.
    Me: 26 (IC/PCOS-2000mg of Metformin daily)

    June 2014- HSG=clear

    DH: 27 (SA results were great minus the slightly low morphology)
    Started dating DH in 2002 at 14 years old
    Married on 03.01.2014
    Officially TTC since April 2014 
    January 2013- Surprise BFP, m/c at 6 weeks, D&C 2 Weeks later
    April 2014- First RE appointment
    July 2014- IUI#1-Canx due to scar tissue and polyps. TI with the help of Ovidrel. BFN

    August 2014- Hysteroscopy to remove scar tissue and polyp

    September 2014- IUI #1.1-100mg Clomid, Ovideral, 11.5 million swimmers=BFP

    EDD-6/3/15- Our sweet baby Ryan was born on 1/6/15 and is in the arms of an Angel

    Dx with IC on 1/6/15



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