I was put on Crinone last week, so about a week and a half ago. I've noticed some discharge since I started it. It's a mix of old brown blood and the progesterone gel, but it looks like chunky coffee grounds - that's the best way that I can describe it. My doctor saw some of this discharge last week and wasn't concerned at all. I had to do a lot of digging on the internet, but I found that Crinone can sometimes irritate the cervix and cause bleeding and spotting, hence the coffee grounds. I know that it was really disconcerting when it started, so that's why I thought I'd share it here, since I know that some of the other ladies are on Crinone as well. I hope this isn't happening to anyone else, but if so, this is what I've found out.