Ibprofen?! — The Bump
Secondary IF

Ibprofen?!

Is it true you shouldn't take ibprofen while ttc?!
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My History:
Lots of BFN's & failed IUI's w/clomid and/or femara
Finally BFP with femara & t.i.- son born 6/17/2010
Started TTC again around when DS was 3ish
Lots of BFN's with femara & t.i & ovidrel
Tubes clear, S.A came back low motility but high count
About to switch to injectables w/femara, did one last cycle with just femara & an IUI with ovidrel- stupid motility was fantastic in the sample, but count was 700,000 AFTER wash! Had to sign a paper to even still do IUI- BFFP (big fat freaking positive) Go figure!
1st Beta 13dpiui 54, 2nd beta 48 hours later 115, 3rd beta 48 hours later 310, 4th beta 72 hours later 1748.

Re: Ibprofen?!

  • I have only heard (via the interwebz, not from my doctor) that it should be avoided around the time of potential implantation. 
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    DX: I'm a Recurrent Loser
    Me (35) + DH (37) - Married Sept. 2007
    BFP #1 - DS born 7/11/11
    BFP#2 11/13/13 - EDD 7/29/14 - M/C at 5w3d
    BFP #3 12/28/13 - EDD 9/7/14 - M/C at 4w6d
    BFP#4 3/27/14 -  EDD 12/5/14 - Girl lost to 45X at 8w6d - D&C 
    BFP#5 10/15/14 - EDD 6/30/15 - M/C at 7w2d
    BFP #6 1/5/15 - EDD 9.16.14 [CLICKY for progress]
    In search of a image


  • I have heard it came thin the lining for implantation as well. I used to take it a lot and switched to Tylenol if need be the last few cycles just in case.
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  • I can tell you when I took it during the first 2 weeks my lining would not be as thick as when I did not take it
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    DX: Severe MFI 9/1/11
    Because of Undescended testicle at birth
    IVF #1 October BFN; 5 snowbabies
    FET: November/December 2011
    ET: 12/7/11; Beta 1: 12/16/11: 66 Beta 2: 12/19/11: 212! 1st ultrasound 1/3/12! Graduated 1/10/12: heartbeat 160
    SAIF Always Welcome
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  • No Ibuprofen in the 2WW and RE's will rec that you not take it at all while you are TTC because they tend to err more on the side of caution. You can't take while you are pregnant, anything that should be avoided during pregnancy, should technically be avoided in the 2ww. 


    Spontaneous pregnancy #1
    DD1 July 31, 2011

    Trying for #2 since Oct 11
    732973 Clomid Cycles
    2 IUIs 
    3 Fresh IVFs= 1 Ectopic treated with MTX
    Spontaneous pregnancy #2= Ectopic #2= lost left tube
    Spontaneous pregnancy #3= DD2 January 29, 2016
    Spontaneous pregnancy #4= Ectopic #3
    Spontaneous pregnancy #5= Baby #3 is a BOY!!! 



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  • Thanks for all the info- I also read it can affect ovulation/implantation
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    My History:
    Lots of BFN's & failed IUI's w/clomid and/or femara
    Finally BFP with femara & t.i.- son born 6/17/2010
    Started TTC again around when DS was 3ish
    Lots of BFN's with femara & t.i & ovidrel
    Tubes clear, S.A came back low motility but high count
    About to switch to injectables w/femara, did one last cycle with just femara & an IUI with ovidrel- stupid motility was fantastic in the sample, but count was 700,000 AFTER wash! Had to sign a paper to even still do IUI- BFFP (big fat freaking positive) Go figure!
    1st Beta 13dpiui 54, 2nd beta 48 hours later 115, 3rd beta 48 hours later 310, 4th beta 72 hours later 1748.
  • According to my RE you should not use any NSAIDs near the time of ovulation.  There have been studies that show NSAID use can cause temporary infertility (originally primarily linked to implantation failure - need some inflammation to have implantation) and I was recently shown an article about a study that shows NSAIDs can cause delays in ovulation.  

    I am on indomethacin for AS.  I had not taken it in years because you aren't supposed to take it while pregnant, I didn't want to take anything more than the bare minimum while breastfeeding and because of the concerns associated with taking NSAIDs while TTC.  After my last two failed IVF cycles, I spoke to my RE about starting it up again.  She said to stop taking it before O and wait until AF arrives to start again if we wanted to continue to TTC on our own while we were trying to decide what we want to do next.  

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    ~SAIF/PAIF/Everyone Welcome~ 

    Me= 37 and DH = 41 

    Dx: DOR, Endo, APA+ (really high beta 2 glycoprotein antibody and high everything else tested), heterozygous MTHFR mutation, positive for lupus anticoagulant, high FSH, low AMH and both tubes blocked (per HSG on 3/8/11)

    IVF #1 - long lupron (with HGH, intralipids, lovenox and BA); 4 retrieved, 3 fertilized; ET 2 blasts and 1 frozen = BFN

    IVF #2 - a version of antagonist with EPP (with HGH, intralipids, lovenox and BA); 6 retrieved, 4 mature, 3 fertilized, 2 blasts and 1 frozen blast transferred on day 5 = BFN.

    IVF #3 April was postponed to May, May was canceled. June/July was canceled. Had a cyst aspiration and then began IVF #3 in August. ER on 8/22; ET on 8/24 with AH. +HPT on 9/5. Beta #1 (11dpo) = 3; Beta #2 (15dpo) = 29; Beta #3 (17dpo) = 60; Beta #4 (19 dpo) = 118. Heartbeat at 6 weeks 6 days =132.  Lil is here!

    TTC#2:  Trigger + TI = BFN; Clomid + Trigger + IUI = BFN.

    IVF #4:  BCP + MDLF + Lovenox = 7R, 1F = Transferred 1 6-cell embryo on day 3 = BFN

    IVF #5:  MDLF + Lovenox = 4R, 1F = Transferred 1 10-cell compacting embryo on day 3 = BFN

    IVF #6:  (New RE):  Long Antagonist November 2014 (transferred two 8 cell grade 1 embryos and froze one blast) = BFN

    FET#1:  BFN

    iheartsippycups2
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