TTC after 35

Is it everybody else, or is it me? (It's me, isn't it?)

I'm 6 dpiui on my first medicated cycle (Follistim and Pregnyl trigger), and I seriously think I'm losing my mind.  My boss just had me re-do large chunks of a letter he'd asked me to write for him (telling me exactly what to say--very "Please take a memo, Miss Davie").  My reaction was part rage (I understand that your PA is on vacation, but I notice you're not asking my male counterpart to spend his time taking care of your correspondence) and part self-pity (I can't take direction and perform simple tasks.  Soon I will be in a coma.  Also, why are you so mean?), but the net effect was that I was almost in tears.

Irritation at the ongoing office sexism is normal for me; the rest is definitely not.  I know logically that if everyone around me was truly as vile and horrendous as I think they are right now, I probably would have noticed it earlier, but it's hard to remember that.   It's not just being short-tempered and emotionally sensitive--I have been in one grim and hopeless freakin' mood for the past couple of days (since the trigger wore off, pretty much).

For those of you who have done medicated cycles, is this typical?  When does it stop?

The upside is that I announced to my husband last night (in actual tears, this time) that there would be changes around the house and that I needed an hour of me-time a day.  He's already moved some things around to make that happen.  DH is exempt from my I-hate-everyone-right-now policy, because he's pretty awesome.


*****Signature/Ticker Warning******

Me: 41, DH: 45
DD, 6/15/2013
TTC #2 beginning January 2014
AMH 1.05; FSH range 7-11

July 2014: IUI #1.  Follistim + Pregnyl.  2 follicles--BFN
September 2014: IUI #2.  Follistim + Pregnyl + Ganirelix + Crinone.  4(?) follicles--BFN
October 2014: IUI #3.  More Follistim + More Ganirelix + Pregnyl + Crinone.  4 follicles--BFP!  Beta #1=10 Beta #2=33 Beta #3=97 Beta #4=158.  M/C 11/1/14
December 2014: IVF #1.  Microdose Lupron protocol.  9R, 9M, 9F.  3 5-day blasts transferred 12/15. BFFN.
April 2015: IVF #2.  Microdose Lupron protocol.  16R, 15M, 12F. Transferred 2 5-day blasts 4/12 and froze 4--BFP!  M/C 5/25/15
August 2015: IVF #3.  14R, 13M, 11F.  Froze 5 blasts for CCS testing.  3 normals.  FET planned for 10/2015.



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Re: Is it everybody else, or is it me? (It's me, isn't it?)

  • I'm sorry. Unfortunately, the mood swings and irrational thoughts are much worse the latter half of a medicated cycle. I always forewarn my husband and coworkers b/c you never know when I'll snap, cry or do both. It is not you, and it will go away.  Until then, get your hour of alone time, read a book, drink some tea, zone out and know this is short term. Big hugs to you...
    Siggy Warning


    TTC#1 since June 2012

    Dx: Unexplained Infertility / AMA

    BFP after 4th IUI cycle with Gonal F + Ovidrel on March 2014 | EDD 12/7/14 | MMC on 4/14/14 

    IUI#5 with Gonal F and Ovidrel trigger on 6/6 - BFN

    On to IVF #1 with a new RE. Started Gonal F and Menopur on 8/15.  Added Ganirelix on 8/24. Trigger on 8/26 for ER on 8/28. 8R 7M 3F.  Transferred all 3 on 8/31. BFP on 9/11 | EDD 5/20/15 - Beta #1: 56.7. Beta #2: 97. Beta #3: 1148. Beta #4: 3559. Beta #4: 7678. MMC confirmed on 10/13. D&C on 10/14 at 9w. Confirmed male with Trisomy 14.

    On to IVF #2 in March. CCS Testing on 2 embies. No go. Waiting to start IVF #3 in July. Surprise BFP on 6/14! EDD - 2/20/16 - Beta #1: 121.4. Beta #2: 236.4. Beta #3: 2014.

    December 4image

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  • I'm a mess on just letrozole, I couldn't imagine being on more drugs. I think the worst part isn't feeling like minor things are the end of the world, it's knowing that you're being irrational and that there's nothing you can do to stop it. 
    Me: 38 DH: 40 TTC#1 (and likely only) since 9/13. Saw RE 5/14, SA good, AMH 2.36, FSH 7.2, estradiol 69.6 indicating good egg reserve. Using OPKs. First Letrozole cycle 6/14, a burst cyst and a BFN. Second Letrozole cycle 7/14, BFN. 

    Update 11/14 - had laparoscopy 10/28, good news is that my uterus and left tube look good, and they were able to drain the cyst on my left ovary. Bad news is that right tube and ovary have endo and scar tissue, so they're pretty useless.. Best news is that we finally have some answers and a path forward. Taking 7.5 mg letrozole CD 2-6 to put that good left ovary through its paces. 

    UPDATE 2/2015 - We switched to another fertility clinic, but fortunately we don't have to start all over. We're doing two cycles of Clomid plus IUI, if neither of those take, we'll do IVF in April, potentially with ICSI. (DH's SA has gone downhill, likely due to excessive exercise.) IUI#1 2/25/15....
  • I think I am in this boat to.  I just started letrozole and norethindrone last night and I wanna crawl back in bed until my RE appt tmw.  I didn't realize this was gonna happen. 

    All those in favor of taking the rest of the day off and having ice cream and watching sappy movies?

    DH and I:  37; TTC since 12/2007
    Me:  8-9 Follicles seen on Initial RE Visit, Letrozole/Norithendrone to manage endometriosis; Baseline CD3 (8/1/14), 7 Follicles seen, AMH low/FSH high,  OvaVite to improve Egg Quality; Hysteroscopy showed polyp, Surgery set for 8/22;
    FemVu showed both tubes clear!; Thyroid Hormone high, Synthorid to normalize
    DH:  Both SA - no living swimmers, Attempting to set up appt with urologist

    Daisypath Anniversary tickers

    "Consider it pure joy, my brothers and sisters, whenever you face trials of many kinds, because you know that the testing of your faith produces perseverance."  James 1:  2-3

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    || [url=http;//www.fertilityfriend.com]Ovulation Chart[/url

  • edited July 2014
    I'm in. I'll bring the ice cream and copy of The Princess Bride.

    Today I had to go in for an US to see if I ovulated, or will soon. After waiting over an hour, they finally took me, and said they couldn't confirm either way and that I needed to come back on Sunday. 

    I made it to the car before I started sobbing hysterically about how nobody at that clinic can ever give a straight answer and that I was going to be at least 15 minutes late for work and I'm NEVER late for work, I'm always early, and why doesn't anyone understand that I can't be late for work just to have a wand shoved up my vag with no answers! I could have gotten the same result by staying home and shoving a cucumber up there, and I would have been on time for work AND made it to the gym! Followed by more sobbing. Meanwhile, the rational me was kind of floating in space, looking down on myself, and wondering what the heck was going on.

    DH is convinced I'm possessed by demons.
    Me: 38 DH: 40 TTC#1 (and likely only) since 9/13. Saw RE 5/14, SA good, AMH 2.36, FSH 7.2, estradiol 69.6 indicating good egg reserve. Using OPKs. First Letrozole cycle 6/14, a burst cyst and a BFN. Second Letrozole cycle 7/14, BFN. 

    Update 11/14 - had laparoscopy 10/28, good news is that my uterus and left tube look good, and they were able to drain the cyst on my left ovary. Bad news is that right tube and ovary have endo and scar tissue, so they're pretty useless.. Best news is that we finally have some answers and a path forward. Taking 7.5 mg letrozole CD 2-6 to put that good left ovary through its paces. 

    UPDATE 2/2015 - We switched to another fertility clinic, but fortunately we don't have to start all over. We're doing two cycles of Clomid plus IUI, if neither of those take, we'll do IVF in April, potentially with ICSI. (DH's SA has gone downhill, likely due to excessive exercise.) IUI#1 2/25/15....
  • CML11CML11 member
    edited July 2014
    I felt crazy on medicated cycles, zero patience and bitchy. I think these work problems would have still been there for you, but everything seems so magnified on these cycles.
    I'm sorry, hang in there!
  • I just wanted to say that I'm sorry for you ladies going through this. Big hugs to all of you!
    Eye on the prize, right? ;)

    Me: 38 ~  DH: 38 ~   DD: 8
    TTC #2 since March/April 2014.
     
     
  • I have no experience with meds but i just wanted to send you a hug  {(you)}
    I don't like that you are feeling like this. 
    SIGGY WARNING
    Me 38   DH 34
    married 05-21-11 
    started TTC right away






    BFP- 10-16-14 EDD 6/13/15: MC 12-1-14 
  • All of you ladies deserve major props! I've not taken meds, but my PMS symptoms can be gruesome enough that I don't want to imagine my wrath on others if I had to take them.

    Definitely get away for a massage, coffee, or me-time.

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                 Visit The Nest!image Visit The Nest!

      "It is better to light a candle than curse the darkness." - Eleanor Roosevelt


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  • I feel the same way and was writing things all backwards today and had to rewrite and wasted lots of paper and I stop listening and I go into the bathroom and cry...I feel your pain! (((HUGS)))
    41 & single; DX:  PCOS
    TTC #1 with IUI and donor sperm
    First IUI May, 2014, Clomid + Trigger = BFN
    Second IUI July, 2014, Clomid + Trigger = BFN
    Third IUI Dec, 2014, Femara + Follistim + Trigger = BFN
    Fourth IUI Feb 2015, Femara + Follistim + Trigger = C/P :(

  • I am on Clomid this month for the first time (took my last dose yesterday) and am set to Trigger with Ovidrel sometime next week. I have a constant dull headache, hot flashes like a mo' fo', and am losing patience by the flippin' second. 

    My mom put my childhood house up for sale today....my dad died in Nov. '12 and this was the last part of him that I feel like I had left. Seeing my house online today had me tearing at my desk. I just want to effing hibernate the rest of the cycle, either that, or drink it away. OH - and to top it off, a coworker who is on maternity leave brought her 7 week old twins, yes...twins....to work today to see everyone. Cue BABY FEVER even more. 

    Today can suck it....for all of us!
    BabyFruit Ticker
    Me: 37 DH: 38 
    BFP #1 3/17/11 - DS born 12/4/11
    TFAS Dec 2013
    BFP #2 - 3/23/14 - CP 3/26/14
    BFP #3 - 8/20/14 - Natural Miscarriage 9/22/14
    BFP #4 - 1/28/15 - DS2 born 10/13/15
    Surprise BFP# 5 - 9/2/16 - Due 5/13/17

  • Thanks, Ladies!  You're the very best, all of you!  I'm sorry for those of you who are also in hormone hell at the moment; I hope it gets better soon.  I second @rose_archangel's day off idea.  Ice cream!

    @Austrogermokee, I hope you get much better answers on Sunday.  So frustrating!
    And, @katie0919, I'm sorry about your father and your childhood home.  That must be really rough.  Hugs.

    I think I'm past the worst of it for this cycle, and had an encouraging appointment with my RE this morning, so I'm feeling better.  I really wasn't expecting this, because I'd never had a bad reaction to hormonal medications (birth control) before.  But now that I know to expect it, maybe it won't be so bad next time.

    Good luck to all of us--it's worth it, right?
    *****Signature/Ticker Warning******

    Me: 41, DH: 45
    DD, 6/15/2013
    TTC #2 beginning January 2014
    AMH 1.05; FSH range 7-11

    July 2014: IUI #1.  Follistim + Pregnyl.  2 follicles--BFN
    September 2014: IUI #2.  Follistim + Pregnyl + Ganirelix + Crinone.  4(?) follicles--BFN
    October 2014: IUI #3.  More Follistim + More Ganirelix + Pregnyl + Crinone.  4 follicles--BFP!  Beta #1=10 Beta #2=33 Beta #3=97 Beta #4=158.  M/C 11/1/14
    December 2014: IVF #1.  Microdose Lupron protocol.  9R, 9M, 9F.  3 5-day blasts transferred 12/15. BFFN.
    April 2015: IVF #2.  Microdose Lupron protocol.  16R, 15M, 12F. Transferred 2 5-day blasts 4/12 and froze 4--BFP!  M/C 5/25/15
    August 2015: IVF #3.  14R, 13M, 11F.  Froze 5 blasts for CCS testing.  3 normals.  FET planned for 10/2015.



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  • Glad your AM appt. went well.  No experience but I hope you next 1WW flies by with a great ending!

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