I have PCOS and have been trying to get pregnant for 18 months. Soon I will start a diabetes prescription to help my ovulation and cycle to help me get pregnant. Has anyone been prescribed Metformin or a different diabetes medicine to help get pregnant with PCOS? If so which one and how long did it take to conceive? Did you have any side effects?
Re: PCOS
I second the recommendation for an RE. They're the experts needed to get you KU!
Just a heads up, the vast majority of women here are still still to conceive their first so we won't be able to tell you any success stories.
I hope you find an RE that can help you with your journey!
Me (29) DH (37)
Married 7/11
Actively TTC 3/12
DX: PCOS
Current treatment: Break from IUIs until after the holidays
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I also have PCOS, but am not insulin resistant (pre-diabetic) nor do I have weight issues. My RE is still going to put me on Metformin soon because insulin apparently can play a role in inhibiting ovulation (who knew!).
I hope I'm not annoying anyone with my links to medical stuff, but this is worth a read if you're considering starting Metformin: https://www.infertilityspecialist.com/metformin_kutner.html
Helpful Excerpt: "Numerous studies have shown that metformin is effective in both obese and thin women correcting insulin metabolism, endocrine parameters or both. Some studies on the effects of metformin have revealed positive trends without achieving statistical significances. This may imply there are subsets of PCOS patients that may not benefit from metformin use."
I like knowing why I'm putting things in my body. My RE is very confident that Metformin and Letrozole will be a successful treatment for my particular PCOS. Everyone is different, but Metformin paired with Letrozole (aka Femera - newer drug with less reported side effects) or Clomid is considered Treatment-As-Usual for PCOS.
I hope this is helpful. Good luck and welcome.
Me: 28 MH:35
Married September 2012. TTC since September 2013
June 2014 - Dx w/ significant PCOS and referred to RE.
July/August 2014 - Testing complete: Testosterone & AMH very high, FSH slightly high, Vitamin D low, tubes and lining all lovely. DH SA: A+
Cycle 1 (Nov 2014): 2.5 mg Letrozole/Ovidrel/TI = BFN
Cycle 2 (Dec 2014): 5 mg Letrozole/Ovidrel/TI - BFN
Cycle 3 (Jan 2015): 5mg Letrozole/Ovidrel/TI - BFN
WTF consult scheduled for 1/29
I have PCOS as well. I actually went off of my Metformin and am getting a new CD3 blood draw done next month as I found the Metformin was making me very dizzy, almost like tunnel vision, and would just make me feel sick and hot. No matter if I ate it before I ate, during, or after. I have a feeling that my blood sugars are getting too LOW after taking it. So we're going to work on that a bit to see if there is anything else I can take since it doesn't seem to be regulating it. I haven't read much about other ladies having that issue though, so if I hear anything helpful at my next blood draw I will let you know.
I hope you get some good info at your appt!
***Signature/Ticker Warning***
March 2008 - DD born - no issues conceiving (surprise). Limited issues during pregnancy/delivery.

June 2011 - Married DH.
June 2013 - Diagnosis of Endometriosis and PCOS (approximate).
December 2013 - First cycle of Clomid - Positive OPK. BFN
January 2014 - 2nd Cycle of Clomid - Positive OPK. BFN
February 2014 - 3rd Cycle of Clomid - Positive OPK. BFN
March 2014 - Took month off to prep for surgery
April 2014 - Laporoscopy for endo. Unable to remove endo due to too close of proximity to ureter. HSG done as well. Fillopian tubes open.
May 2014 - 1st round of Femara. Positive OPK. BFN.
June 2014 - 2nd round of Femara. Moved to RE to have CD10 Follicular U/S. No Follies in left ovary. 5 follies in right. Largest follie 8mm, 1 7mm, 2 3mm, 1 2mm. Positive OPK on day of U/S. BFN. DH has SA done at this time - All results within normal limits.
July 2014 - 3rd round of Femara. CD10 Follicular U/S. No follies in left ovary. 7 follies in right. 1 20mm, 1 12mm, 1 10mm, 4 <5mm. Scheduled for IUI. Canceled due to low estrogen level of 145. TI this month. Prepping for Injectables next month. BFN.
August 2014 - CD3 BW Normal. Injectables not happening because of stupid miscommunication about "required injectables class." Taking class this month. No medication. TI for the month. SIS scheduled for 8/7/14. SIS results - "I have a beautiful uterus." Huzzah!
September 2014 - Cycle cancelled due to stupid AF coming early and making my IUI run in to DH's business trip. Try again next month.
October 2014 - Injects with IUI cycle. 75U 5 days. Estrogen at 36. Bumped up to 125 for 4 days. Estrogen 105. Bumped up to 225. Ganirelix for 2 days. 4 mature follies. Triggered 10/9. IUI 10/10.
BFP 10/24/2014. Beta #1 - 178 Beta #2 - 398. U/S 11/7/14- TWINS!!!!
TTC #1 with IUI and donor sperm
First IUI May, 2014, Clomid + Trigger = BFN
Second IUI July, 2014, Clomid + Trigger = BFN
Third IUI Dec, 2014, Femara + Follistim + Trigger = BFN
Fourth IUI Feb 2015, Femara + Follistim + Trigger = C/P
As others have mentioned, most of the women on this board have never been pregnant, so you are less likely to hear success stories/info here. You may want to try the Pregnant after IF or Success after IF boards for that.
However, this board is filled with wonderfully supportive women who understand what you are going through.
ME: 34, Atypical PCOS (lean, no O without meds) + unexplained; DH: 33, mildly low motility
09/2012: Start TTC after stopping NuvaRing. No cycles seemed to occur.
01/2013 - 05/2013: Tried Provera to "jumpstart" cycles. No luck.
12/2013- 01/2014: Clomid 50mg - no big follies, stepped to 100mg; One mature follie, Ovidrel (HCG trigger), IUI #1 completed - BFN
02/2014: Clomid 100mg; One mature follie, Ovidrel trigger, IUI #2 completed, Crinone - BFN
03/2014: Clomid 100mg - no big follies on 1st round, 2nd round prescribed; One mature follie, Ovidrel, IUI #3 completed, Crinone - BFN
04/2014-05/2014: Letrozole 5mg + Ovidrel HG to prep for IUI #4 switched to TI, Crinone - BFN
05/2014-06/2014: Letrozole 5mg; one mature follie, Ovidrel, IUI #4.1 completed, Crinone - BFN
07/2014-08/2014: Letrozole 5mg; one mature follie, Ovidrel, IUI #5 completed, Crinone - BFN
09/2014-10/2014: IVF Prep - Insurance requires IUI #6; Letrozole 5mg - no big follies 1st round, 2nd round prescribed; IUI #6, Crinone - BFN
11/2014: "Break" - Letrozole 5mg to cycle before prepping for IVF - successfully O'ed, but BFN
12/2014: Extending 'break' one more Letrozole-only TI cycle for mental health break - BFN
01/2015-02/2015: Prep for IVF - BCP then Gonal-F, Ganirelex, Novarel trigger; ER scheduled 2/11!
http://www.fertilityfriend.com/home/4cf919
PAIF/SAIF Welcome.