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Low E2 for 2 follicles?

tweetyknickstweetyknicks member
in Trouble TTC
I'm approaching IUI#2.1 on Sunday (trigger tonight). The nurse said that with two follicles 17-19mm, my E2 is 238 (up from 69 two days ago). Does that seem kind of low, given that the usual guideline is 15-200 per mature follicle? And is that guideline for the day of trigger or the day of IUI? 


***siggy warning***

Me: 29; DH: 53
TTC since February 2013 --- mild thin PCOS (or not, depending on which RE you ask), MFI

TI#1: BFN (April 2014; Clomid 50mg x5 days, Estrace x5 days, Clomid 50 mg x4 days)
IUI#1: c/p (May 2014; Letrozole 2.5 mg x5 days, Estrace x5 days, Bravelle 75 IU x10 days)
IUI#2: abandoned... O'd early & DH hormone issues (June 2014; Letrozole 2.5 mg x5 days, Bravelle 75 IU x2 days)
IUI#2.1: BFN (July 2014; Letrozole 2.5 mg x5 days, Bravelle 75 IU x4 days)

Moving on to IVF. (Why we're moving on to IVF)

IVF#1 (w/ICSI): BCP 9/9-9/23. Gonal-F, Ganirelix, Low-dose HCG (antagonist protocol). 41R/35M/32F... 2 transferred on 10/14, 14 frosties! On cabergoline to help avoid OHSS. BFN, possibly because of 90% drop in estrogen and progesterone a few days after ET.
FET#1: Transferring 2 on January 8. BFP! beta#1 (1/17): 408, beta#2 (1/20): 1310, first u/s scheduled 2/5

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Re: Low E2 for 2 follicles?

  • BunnyBerryBunnyBerry member
    Sorry, I am not familiar enough to know. I always thought the E2 of 150-200 per follicle is before the LH surge but I could be wrong. 

    Good luck on Sunday. :)
    January 3T Siggy Challenge - New Year's Resolutions
    image
    imageimage

    Me (29), DH (30) TTC actively 54 55+ cycles | All BFNs
    MFI (low everything) | Endo Stage 1 & Stenotic Cervix (treated) | PCO
    Married - July 2008 | Started TTC - Jan 2009 | RE Visit #1 - Mar 2014 
    IUI #1 ICI #1 - June | IUI #1.1 Laparoscopy - Aug
    IUIs #1.2, 2, 3 - Sept, Oct, Nov (Letrozole) - BFNs 
    IUI #4 - Dec (Bravelle) | IUI #5 - Dec/Jan (Bravelle) - 5 follies + TI - BFNs
    IUI #5.1 - Jan (Bravelle) Cancelled 
    Planning to start IVF in March!
    ***All Welcome***
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  • catlover790catlover790 member
    I am not sure but wanted to wish you good luck!
    ***********siggy warning **********



    Me: 26 DH: 27
    TTC #1 Since Aug. 2013
    Cycle 1: O CD 25=bfn
    Cycle 2: O CD 48=bfn
    Cycle 3: Anovulatory/Provera =120 days!
    Cycle 4: Anovulatory/Prometrium=127 days! RE consult 6/16
    Me: Anov/poss. pcos?  HSG=normal/SA= Normal 
    July/Aug. 2014= Femara+trigger+TI=BFP!!
    Beta #1@ 16dpo=626!! Beta #2=1510
    Ultrasound @ 5w6d=heartbeat at 110!
    Ultrasound @ 6w6d =heartbeat at 131!


    Pregnancy Ticker

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  • Waterlily234Waterlily234 member
    I think the fact that your number has increased is good and it will keep going as well. Good luck today!

    ME:      36, on BC since 1996,  irregular periods.   HUBS:      37, healthy

    2001—meet.  2005—marry.  2006—Furbaby is born. 

    On BC till end of 2009.  2010 NTNP.   

    New Year’s Eve 2010—BFP?! January 13, 2011—early loss, HCG peaked at 324, no D&C needed.

    +++++

    Feb 2011-Nov 2012—NTNP 

    Dec 2012 --present (TTC 20 months) Not even a hint of a BFP

    Me:  BW, U/S, HSG, HSN normal.  AMH 2.33.  Hubs: SA normal 

    +++++

    April 2014--IUI #1 Clomid 100 4-8 Follistim 150 9-14, 5 mature follies at trigger, Peak E2 5/5 1100, BFN 

    May 2014 ---IUI#2 Clomid 100 3-7 Follistim 150 8-13, 3 mature follies at trigger, Peak E2 6/6 547, BFN

    June 2014--IUI#3 Follistim 150/225 3-15, 3-5 mature follies at trigger, Peak E2 7/11 1450, BFN

    July 2014--IUI#4 Follistim 225 2-12, 3 mature follies at trigger, Peak E2 8/12 841, BFN

    Breaking till after Christmas, then IVF...taking 4000 mgs daily Inositol and Melatonin 3mg


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  • tweetyknickstweetyknicks member
    Thanks for all your encouragement. I suspect E2 increased a bunch before the IUI. I was never clear if the 150-200 guideline is at the time of trigger or at the time of ovulation. (I did mean 150-200 in the original post, but apparently had trouble typing.)

    The IUI was not exactly flawless (as in, ow), but I don't think there was any functional problem with the way it went. I'm hopeful that at least one of those two that appeared ready will stick!


    ***siggy warning***

    Me: 29; DH: 53
    TTC since February 2013 --- mild thin PCOS (or not, depending on which RE you ask), MFI

    TI#1: BFN (April 2014; Clomid 50mg x5 days, Estrace x5 days, Clomid 50 mg x4 days)
    IUI#1: c/p (May 2014; Letrozole 2.5 mg x5 days, Estrace x5 days, Bravelle 75 IU x10 days)
    IUI#2: abandoned... O'd early & DH hormone issues (June 2014; Letrozole 2.5 mg x5 days, Bravelle 75 IU x2 days)
    IUI#2.1: BFN (July 2014; Letrozole 2.5 mg x5 days, Bravelle 75 IU x4 days)

    Moving on to IVF. (Why we're moving on to IVF)

    IVF#1 (w/ICSI): BCP 9/9-9/23. Gonal-F, Ganirelix, Low-dose HCG (antagonist protocol). 41R/35M/32F... 2 transferred on 10/14, 14 frosties! On cabergoline to help avoid OHSS. BFN, possibly because of 90% drop in estrogen and progesterone a few days after ET.
    FET#1: Transferring 2 on January 8. BFP! beta#1 (1/17): 408, beta#2 (1/20): 1310, first u/s scheduled 2/5

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