TTC after 35

Decisions, decisions--decision made! (Update)

Davie813Davie813 member
edited July 2014 in TTC after 35
So I had my RE consult yesterday, and I'm feeling a bit discouraged.  (To be fair, she was very nice and didn't actually say anything discouraging; it's just all real now.) :|

She definitely didn't proffer a "quick fix": she said that everything looked great and that the likely cause of our problem was simply age and the shortage of normal eggs that comes with it.  Great.

Anyway, these are my options:

1. Complete the three IUIs with clomid my insurance requires before moving on to something more aggressive.  The RE gives these a 6% chance of success each.

2. See if she can convince my insurance company (based on my age and previous FSH of 11) to move directly to IUI with injectibles.  She gives these an 18% chance of success each (and, if successful, a 20% chance of resulting in twins).

3. Move directly (if insurer agrees) to IVF.  She gives this a 40% chance of success each (which seems high to me, but is based on the assumption that we're able to harvest/grow high-quality embryos.  Based on my age, bloodwork, and history, she thinks we will be.)  She gives this the same risk of producing twins, unless we transfer fewer embryos to avoid that--in which case it's obviously less likely to work at all.

I'm not at all sure what to do.  Part of me wants to start with something less invasive than IVF, for a variety of reasons.  Part of me is worried that I'm running out of time and should be as aggressive as possible.  I would also like to start looking for a new job at some point, and I'm obviously limited by insurance until I get pregnant or give up.  Yet another wrinkle is the fact that DH is terrified of the idea of twins and wants to do everything possible to avoid it.  I don't think that would be the most desirable outcome either, but I'm more willing to do whatever it takes to get pregnant. 

I know nobody can make the decision but DH and I, but any thoughts or words of wisdom?  How did those of you receiving fertility treatment decide what course to take?

ETA: nothing against twins (or large families).  We're just concerned about medical complications, and while we could support three kids, it would be very tight for a while!


*****Signature/Ticker Warning******

Me: 41, DH: 45
DD, 6/15/2013
TTC #2 beginning January 2014
AMH 1.05; FSH range 7-11

July 2014: IUI #1.  Follistim + Pregnyl.  2 follicles--BFN
September 2014: IUI #2.  Follistim + Pregnyl + Ganirelix + Crinone.  4(?) follicles--BFN
October 2014: IUI #3.  More Follistim + More Ganirelix + Pregnyl + Crinone.  4 follicles--BFP!  Beta #1=10 Beta #2=33 Beta #3=97 Beta #4=158.  M/C 11/1/14
December 2014: IVF #1.  Microdose Lupron protocol.  9R, 9M, 9F.  3 5-day blasts transferred 12/15. BFFN.
April 2015: IVF #2.  Microdose Lupron protocol.  16R, 15M, 12F. Transferred 2 5-day blasts 4/12 and froze 4--BFP!  M/C 5/25/15
August 2015: IVF #3.  14R, 13M, 11F.  Froze 5 blasts for CCS testing.  3 normals.  FET planned for 10/2015.



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Re: Decisions, decisions--decision made! (Update)

  • Could you find out what it is about twins that terrifies him specifically? We tend to have preconceived notions of what something we haven't experienced is like, but they are often wrong. So perhaps pinpointing his exact concern(s) and then reassuring him with some real-world info would help?
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  • I have no experience with fertility treatments, but if it was me, I would go with #2…IUI with injectables first. If your RE is telling you that your only issue is “age”, then you may have a higher chance of an IUI pregnancy without having to do the IVF. I used to work for CIGNA Healthcare (a big health insurance company), and we always approved IUI before approving IVF. The nurses that did the medical approval at the insurance company made the customers do IUI first, then if it didn’t work, move on to IVF.

    My first step would be to call the insurance company, see what is covered and then go from there. I know some medical reviews can take weeks/months, so you want to find out asap.

    As far as the fear of twins goes, that is just the chance you two have to take. If you want a baby, why not have two babies?! I know it might be a lot of work in the beginning, but your main goal now is to just get pregnant, right? Twins or no twins…just having a healthy baby is all that matters. 

  • PS And being "tight for a while" (as long as all their health and development needs are met, of course) is good for children in the long term, I swear!
  • My RE asked how we felt about twins, the response was, "We only want one child, but two is better than zero." 

    How much time do you have to decide?
    Me: 38 DH: 40 TTC#1 (and likely only) since 9/13. Saw RE 5/14, SA good, AMH 2.36, FSH 7.2, estradiol 69.6 indicating good egg reserve. Using OPKs. First Letrozole cycle 6/14, a burst cyst and a BFN. Second Letrozole cycle 7/14, BFN. 

    Update 11/14 - had laparoscopy 10/28, good news is that my uterus and left tube look good, and they were able to drain the cyst on my left ovary. Bad news is that right tube and ovary have endo and scar tissue, so they're pretty useless.. Best news is that we finally have some answers and a path forward. Taking 7.5 mg letrozole CD 2-6 to put that good left ovary through its paces. 

    UPDATE 2/2015 - We switched to another fertility clinic, but fortunately we don't have to start all over. We're doing two cycles of Clomid plus IUI, if neither of those take, we'll do IVF in April, potentially with ICSI. (DH's SA has gone downhill, likely due to excessive exercise.) IUI#1 2/25/15....
  • Davie813Davie813 member
    edited July 2014
    @marijaa333, it's the finances that freak him out--daycare now, and college later (among other things).  And I agree that those numbers are scary, but people in circumstances like ours do have three kids.  All the time.  They make it work, and so would we.

    @lgsdesigner, it's all covered.  They typically require the clomid IUIs before approving other things, but they can be flexible if circumstances demand it.  They'll only cover a limited number of both IUIs and IVFs, though.

    @Austrogermokee, that's exactly what I say.  DH, on the other hand, feels exactly the opposite.  He does want DD to have a sibling, but he would strongly prefer having one kid to having three.  To be fair, he has said that if we did conceive twins, he would obviously love and welcome them once they were a reality.   He just doesn't want to up the odds.  We need to decide by the end of the week (ack!)


    *****Signature/Ticker Warning******

    Me: 41, DH: 45
    DD, 6/15/2013
    TTC #2 beginning January 2014
    AMH 1.05; FSH range 7-11

    July 2014: IUI #1.  Follistim + Pregnyl.  2 follicles--BFN
    September 2014: IUI #2.  Follistim + Pregnyl + Ganirelix + Crinone.  4(?) follicles--BFN
    October 2014: IUI #3.  More Follistim + More Ganirelix + Pregnyl + Crinone.  4 follicles--BFP!  Beta #1=10 Beta #2=33 Beta #3=97 Beta #4=158.  M/C 11/1/14
    December 2014: IVF #1.  Microdose Lupron protocol.  9R, 9M, 9F.  3 5-day blasts transferred 12/15. BFFN.
    April 2015: IVF #2.  Microdose Lupron protocol.  16R, 15M, 12F. Transferred 2 5-day blasts 4/12 and froze 4--BFP!  M/C 5/25/15
    August 2015: IVF #3.  14R, 13M, 11F.  Froze 5 blasts for CCS testing.  3 normals.  FET planned for 10/2015.



    Baby Birthday Ticker Ticker

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  • It's great that you have such a thoughtful and concerned hubby. I see his point, but also agree that people make it work. 

  • Looking at the odds and thinking when DH and I first starting talking with our RE, I wouldn't see any harm in trying the IUI with injectables (if insurance allows) and taking one cycle at a time (and hopefully it works in one!). I get what your saying about worrying about running out of time and wouldn't want to worry that I was starting off with the option that had the lowest rate of success projected for me. 

    20% sounds like a lot, but really it's not a guarantee that it will happen.  I think of it as 1 in 5 pregnancies results in twins. My good friend has one year old twins and a four year old. She tells me that it has been a lot of work at times, but has gotten easier as they have learned to walk and no longer need bottles. They also have a great support system to help out. 

    Best of luck in your decision!
    **** Warning: Children/Loss Mentioned ****

    Natural cycle BFP 7/09; "baby bear" born 3/10
    Natural cycles starting 7/10; two cycles with clomid = BFP 12/10; m/c 2/2011 
    Cycle #3 with clomid = BFP 5/11; "baby lamb" born 2/12
    Natural cycles starting Nov 2013; 1/13 chemical pregnancy
    RE Apr 2014 Dx = hypothryoidism (Rx for synthroid)
    BFP 6/2014 Baby #3 due Feb 2015
     
  • OK, as someone who has done five IUIs with injectables, and had nothing medically wrong with me except for my age (FSH is 8.6), I would recommend option #2 for maybe two tries; three at the most. Because you were able to conceive naturally, I would think you'd have better odds. I wish I could continue IUIs, but time is running out for me. I have a success rate of 20% for IVF at my age (41) and FSH level. My previous doc said 40%, so that is what I'll focus on. Don't worry about multiples. If it happens, it is a double blessing. :)

    Just my two cents for what it is worth...good luck in your decision making.

    Siggy Warning


    TTC#1 since June 2012

    Dx: Unexplained Infertility / AMA

    BFP after 4th IUI cycle with Gonal F + Ovidrel on March 2014 | EDD 12/7/14 | MMC on 4/14/14 

    IUI#5 with Gonal F and Ovidrel trigger on 6/6 - BFN

    On to IVF #1 with a new RE. Started Gonal F and Menopur on 8/15.  Added Ganirelix on 8/24. Trigger on 8/26 for ER on 8/28. 8R 7M 3F.  Transferred all 3 on 8/31. BFP on 9/11 | EDD 5/20/15 - Beta #1: 56.7. Beta #2: 97. Beta #3: 1148. Beta #4: 3559. Beta #4: 7678. MMC confirmed on 10/13. D&C on 10/14 at 9w. Confirmed male with Trisomy 14.

    On to IVF #2 in March. CCS Testing on 2 embies. No go. Waiting to start IVF #3 in July. Surprise BFP on 6/14! EDD - 2/20/16 - Beta #1: 121.4. Beta #2: 236.4. Beta #3: 2014.

    December 4image

  • If the twin thing is a worry for both of you then try and go right for the IVF and only transfer 1at a time. The success rate is higher so I would go that route. I'm sure your RE knows how to navigate the ins co to get it approved.
    Whichever you choose good luck.

      Me:39, DH:40

    DD born 8/96, DS born 8/04

    TTC#3

    NTNP since 2006, active trying 1/13

    Natural M/C 3/13 at 7 weeks

    CP 2/14

    Daisypath Anniversary tickers

             imageimage

    All welcome

  • I'm sorry the consult was discouraging.

    Based on my unsuccessful experience, I regret not going directly to IVF at age 39, FSH 9.5. Unfortunately, there is no way to know if 6 months will make a difference in response until after the fact. 

    You could try one cycle of injectables to see your response. If it's good, try a few IUIs. If it's bad, you can jump to IVF.

  • IFinTN said:
    I would go straight to IVF, especially if your insurance covers it. You can do a single embryo transfer and unless it splits (it happens RARELY) you will have reduced the risks of multiples from IUIs with injects. My 2 cents. I wish I had not wasted time with IUIs. Good luck!
    I hardly feel qualified to share my perspective, but my initial response is similar to the thoughts of @hooligans4 and @IFinTN.

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      "It is better to light a candle than curse the darkness." - Eleanor Roosevelt


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  • Ticker warning-----


    I hope you don't mind my responding. Unless your DH has MFI, the insurer is unlikely to waive the IUI requirements. I would 100% say go straight to IVF but I don't think you will get the waiver. FWIW, my FSH started off at 12 at age 37 and went up rather fast during 37-38. Get those eggs before you get higher. You can transfer just one embryo to "mostly" avoid twins (unless it splits but that's not too often). Also, clomid made my FSH jump up so if you can get clomid waived, I'd try that. Just my 2 cents as someone who wasted a very precious 6 months on IUIs....

    TTC #1 since 8/1/10; Me:41 and BRCA1+, DH:46
    DOR (FSH 24.3)/ terrible egg quality ; homozygous MTHFR c677t
    5 IUI's: 2/11 to 6/11 and 1/12= BFN
    OE IVF#1-4 8/11-6/12= all BFN
    DE IVF#1 11/12 bad embryos= BFN
    DE IVF #2 2/13 BFP/Beta hell: m/c 5w6d
    CFNBC 7 months, not doing well; decided on guarantee program at RBA w/frozen DE
    DE IVF #3 1/14  ET 4BB; BFP;M/C 5w1d, incomplete m/c; MVA extraction in ER 7w1d

    DE FET#1 ET 3/1714; BFP, beta 1 3/27= 197, beta 2 3/31= 1586, beta 3 4/7= 13879!!
    First u/s= Twins with HBs at 6w2d! We are Team Pink x 2!!

    K & K born 11/21/14 at 38wks 4 days

    imageimage

    SAIF/PAIF Welcome


    http://waitingforraintostop.wordpress.com

  • Sometimes when you have multiple choices it makes it that much harder of a choice. I would try to do the ivf if I were in your shoes
  • tlc35tlc35 member

    IFinTN said:
    I would go straight to IVF, especially if your insurance covers it. You can do a single embryo transfer and unless it splits (it happens RARELY) you will have reduced the risks of multiples from IUIs with injects. My 2 cents. I wish I had not wasted time with IUIs. Good luck!
    This.  I would be as aggressive as your insurance will let your be.
    Me: 37                                               
    DH: 45
    BFP #1 3/19/14  EDD 11/29/14 MMC D&C 4/24/14
    BFP #2  12/4/14 Beta #1 218 at 12dpo Beta #2 1055 at 16dpo
    Saw heartbeat 12/29.  Please be a rainbow.
    imagerainbows
              
    All welcome                                   
                              
  • I agree with several of the PP: I actually regret that I spent 5 cycles trying IUI and didn't go straight to IVF, mainly because of my age. I didn't want anything invasive at first and because I had become pregnant easily 4 years ago I figured it would be the same. Not so. Don't waste too much time, you might still have to do IVF several times. And the twin probability is lowered if you transfer just one egg at a time. However, I was told that when they transfer a blastocyst there is also a higher chance that it will split into two, so the chance of twins is still higher. 

    Good luck with the decision, I know it's hard, and even more when insurance has to be dealt with too. 
    Single mom of DD (2010), TTC #2 since June 2013.
    Occasionally I'm blogging about my life with flybaby.
  • Congrats on deciding! FX for a perfect IUI!
  • Best of luck to you, @Davie813. If you have any questions, please don't hesitate to ask.

    FYI - the time I did get pregnant, I had 4 viable follicles. Only one took. :)
    Siggy Warning


    TTC#1 since June 2012

    Dx: Unexplained Infertility / AMA

    BFP after 4th IUI cycle with Gonal F + Ovidrel on March 2014 | EDD 12/7/14 | MMC on 4/14/14 

    IUI#5 with Gonal F and Ovidrel trigger on 6/6 - BFN

    On to IVF #1 with a new RE. Started Gonal F and Menopur on 8/15.  Added Ganirelix on 8/24. Trigger on 8/26 for ER on 8/28. 8R 7M 3F.  Transferred all 3 on 8/31. BFP on 9/11 | EDD 5/20/15 - Beta #1: 56.7. Beta #2: 97. Beta #3: 1148. Beta #4: 3559. Beta #4: 7678. MMC confirmed on 10/13. D&C on 10/14 at 9w. Confirmed male with Trisomy 14.

    On to IVF #2 in March. CCS Testing on 2 embies. No go. Waiting to start IVF #3 in July. Surprise BFP on 6/14! EDD - 2/20/16 - Beta #1: 121.4. Beta #2: 236.4. Beta #3: 2014.

    December 4image

  • Sounds like a wise decision. Best of luck!
  • marijaa333marijaa333 member
    edited July 2014
    Great to hear you've made the decision AND that DH is more comfortable with the potential for twins, as well as having a back-up plan! Well done.

    PS What does ETA stand for in this case?

    ETA: Thanks!
  • Edited to add :)
    *****Signature/Ticker Warning******

    Me: 41, DH: 45
    DD, 6/15/2013
    TTC #2 beginning January 2014
    AMH 1.05; FSH range 7-11

    July 2014: IUI #1.  Follistim + Pregnyl.  2 follicles--BFN
    September 2014: IUI #2.  Follistim + Pregnyl + Ganirelix + Crinone.  4(?) follicles--BFN
    October 2014: IUI #3.  More Follistim + More Ganirelix + Pregnyl + Crinone.  4 follicles--BFP!  Beta #1=10 Beta #2=33 Beta #3=97 Beta #4=158.  M/C 11/1/14
    December 2014: IVF #1.  Microdose Lupron protocol.  9R, 9M, 9F.  3 5-day blasts transferred 12/15. BFFN.
    April 2015: IVF #2.  Microdose Lupron protocol.  16R, 15M, 12F. Transferred 2 5-day blasts 4/12 and froze 4--BFP!  M/C 5/25/15
    August 2015: IVF #3.  14R, 13M, 11F.  Froze 5 blasts for CCS testing.  3 normals.  FET planned for 10/2015.



    Baby Birthday Ticker Ticker

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    My Ovulation Chart


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  • So glad you were able to sit down with your DH and come up with a plan! I wish you the best of luck!! @Davie813
    Me: 38 ~  DH: 38 ~   DD: 8
    TTC #2 since March/April 2014.
     
     
  • Glad you and DH was able to talk and come to a decision. Good luck with the iui,
  • tlc35tlc35 member
    So glad you have a plan.  This will also give your RE an idea how your body responds to injectables as well.
    Me: 37                                               
    DH: 45
    BFP #1 3/19/14  EDD 11/29/14 MMC D&C 4/24/14
    BFP #2  12/4/14 Beta #1 218 at 12dpo Beta #2 1055 at 16dpo
    Saw heartbeat 12/29.  Please be a rainbow.
    imagerainbows
              
    All welcome                                   
                              
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