So I had my RE consult yesterday, and I'm feeling a bit discouraged. (To be fair, she was very nice and didn't actually say anything discouraging; it's just all
real now.)

She definitely didn't proffer a "quick fix": she said that everything looked great and that the likely cause of our problem was simply age and the shortage of normal eggs that comes with it. Great.
Anyway, these are my options:
1. Complete the three IUIs with clomid my insurance requires before moving on to something more aggressive. The RE gives these a 6% chance of success each.
2. See if she can convince my insurance company (based on my age and previous FSH of 11) to move directly to IUI with injectibles. She gives these an 18% chance of success each (and, if successful, a 20% chance of resulting in twins).
3. Move directly (if insurer agrees) to IVF. She gives this a 40% chance of success each (which seems high to me, but is based on the assumption that we're able to harvest/grow high-quality embryos. Based on my age, bloodwork, and history, she thinks we will be.) She gives this the same risk of producing twins, unless we transfer fewer embryos to avoid that--in which case it's obviously less likely to work at all.
I'm not at all sure what to do. Part of me wants to start with something less invasive than IVF, for a variety of reasons. Part of me is worried that I'm running out of time and should be as aggressive as possible. I would also like to start looking for a new job at some point, and I'm obviously limited by insurance until I get pregnant or give up. Yet another wrinkle is the fact that DH is
terrified of the idea of twins and wants to do everything possible to avoid it. I don't think that would be the most desirable outcome either, but I'm more willing to do whatever it takes to get pregnant.
I know nobody can make the decision but DH and I, but any thoughts or words of wisdom? How did those of you receiving fertility treatment decide what course to take?
ETA: nothing against twins (or large families). We're just concerned about medical complications, and while we
could support three kids, it would be very tight for a while!
*****Signature/Ticker Warning******Me: 41, DH: 45
DD, 6/15/2013
TTC #2 beginning January 2014
AMH 1.05; FSH range 7-11
July 2014: IUI #1. Follistim + Pregnyl. 2 follicles--BFN
September 2014: IUI #2. Follistim + Pregnyl + Ganirelix + Crinone. 4(?) follicles--BFN
October 2014: IUI #3. More Follistim + More Ganirelix + Pregnyl + Crinone. 4 follicles--BFP! Beta #1=10 Beta #2=33 Beta #3=97 Beta #4=158. M/C 11/1/14
December 2014: IVF #1. Microdose Lupron protocol. 9R, 9M, 9F. 3 5-day blasts transferred 12/15. BFFN.
Re: Decisions, decisions--decision made! (Update)
I have no experience with fertility treatments, but if it was me, I would go with #2…IUI with injectables first. If your RE is telling you that your only issue is “age”, then you may have a higher chance of an IUI pregnancy without having to do the IVF. I used to work for CIGNA Healthcare (a big health insurance company), and we always approved IUI before approving IVF. The nurses that did the medical approval at the insurance company made the customers do IUI first, then if it didn’t work, move on to IVF.
My first step would be to call the insurance company, see what is covered and then go from there. I know some medical reviews can take weeks/months, so you want to find out asap.
As far as the fear of twins goes, that is just the chance you two have to take. If you want a baby, why not have two babies?! I know it might be a lot of work in the beginning, but your main goal now is to just get pregnant, right? Twins or no twins…just having a healthy baby is all that matters.
My BFP Chart
@lgsdesigner, it's all covered. They typically require the clomid IUIs before approving other things, but they can be flexible if circumstances demand it. They'll only cover a limited number of both IUIs and IVFs, though.
@Austrogermokee, that's exactly what I say. DH, on the other hand, feels exactly the opposite. He does want DD to have a sibling, but he would strongly prefer having one kid to having three. To be fair, he has said that if we did conceive twins, he would obviously love and welcome them once they were a reality. He just doesn't want to up the odds. We need to decide by the end of the week (ack!)
Me: 41, DH: 45
DD, 6/15/2013
TTC #2 beginning January 2014
AMH 1.05; FSH range 7-11
July 2014: IUI #1. Follistim + Pregnyl. 2 follicles--BFN
September 2014: IUI #2. Follistim + Pregnyl + Ganirelix + Crinone. 4(?) follicles--BFN
October 2014: IUI #3. More Follistim + More Ganirelix + Pregnyl + Crinone. 4 follicles--BFP! Beta #1=10 Beta #2=33 Beta #3=97 Beta #4=158. M/C 11/1/14
December 2014: IVF #1. Microdose Lupron protocol. 9R, 9M, 9F. 3 5-day blasts transferred 12/15. BFFN.
August 2015: IVF #3. 14R, 13M, 11F. Froze 5 blasts for CCS testing. 3 normals. FET planned for 10/2015.
My Ovulation Chart
Just my two cents for what it is worth...good luck in your decision making.
TTC#1 since June 2012
Dx: Unexplained Infertility / AMA
BFP after 4th IUI cycle with Gonal F + Ovidrel on March 2014 | EDD 12/7/14 | MMC on 4/14/14
IUI#5 with Gonal F and Ovidrel trigger on 6/6 - BFN
On to IVF #1 with a new RE. Started Gonal F and Menopur on 8/15. Added Ganirelix on 8/24. Trigger on 8/26 for ER on 8/28. 8R 7M 3F. Transferred all 3 on 8/31. BFP on 9/11 | EDD 5/20/15 - Beta #1: 56.7. Beta #2: 97. Beta #3: 1148. Beta #4: 3559. Beta #4: 7678. MMC confirmed on 10/13. D&C on 10/14 at 9w. Confirmed male with Trisomy 14.
On to IVF #2 in March. CCS Testing on 2 embies. No go. Waiting to start IVF #3 in July. Surprise BFP on 6/14! EDD - 2/20/16 - Beta #1: 121.4. Beta #2: 236.4. Beta #3: 2014.
Whichever you choose good luck.
Me:39, DH:40
DD born 8/96, DS born 8/04
TTC#3
NTNP since 2006, active trying 1/13
Natural M/C 3/13 at 7 weeks
CP 2/14
All welcome
"It is better to light a candle than curse the darkness." - Eleanor Roosevelt
I hope you don't mind my responding. Unless your DH has MFI, the insurer is unlikely to waive the IUI requirements. I would 100% say go straight to IVF but I don't think you will get the waiver. FWIW, my FSH started off at 12 at age 37 and went up rather fast during 37-38. Get those eggs before you get higher. You can transfer just one embryo to "mostly" avoid twins (unless it splits but that's not too often). Also, clomid made my FSH jump up so if you can get clomid waived, I'd try that. Just my 2 cents as someone who wasted a very precious 6 months on IUIs....
TTC #1 since 8/1/10; Me:41 and BRCA1+, DH:46
DOR (FSH 24.3)/ terrible egg quality ; homozygous MTHFR c677t
5 IUI's: 2/11 to 6/11 and 1/12= BFN
OE IVF#1-4 8/11-6/12= all BFN
DE IVF#1 11/12 bad embryos= BFN
DE IVF #2 2/13 BFP/Beta hell: m/c 5w6d
CFNBC 7 months, not doing well; decided on guarantee program at RBA w/frozen DE
DE IVF #3 1/14 ET 4BB; BFP;M/C 5w1d, incomplete m/c; MVA extraction in ER 7w1d
DE FET#1 ET 3/1714; BFP, beta 1 3/27= 197, beta 2 3/31= 1586, beta 3 4/7= 13879!!
First u/s= Twins with HBs at 6w2d! We are Team Pink x 2!!
K & K born 11/21/14 at 38wks 4 days
SAIF/PAIF Welcome
http://waitingforraintostop.wordpress.com
This. I would be as aggressive as your insurance will let your be.
DH: 45
BFP #1 3/19/14 EDD 11/29/14 MMC D&C 4/24/14
BFP #2 12/4/14 Beta #1 218 at 12dpo Beta #2 1055 at 16dpo
Saw heartbeat 12/29. Please be a rainbow.
All welcome
After reading these, I was all set to proceed right to IVF with one embryo (and that's where DH was all along). So, we sat down and started discussing the finer points of the course we thought we'd agreed on--and talked ourselves right out of it!
Right now, neither he nor I are quite comfortable with IVF (for a lot of reasons, many of which have to do with his being Catholic) although not so uncomfortable that we will hesitate to pursue it in the future if need be.
We decided to try two cycles of IUI with injectibles (ables? Stupid spelling)--or only one, if I respond badly to the first. I feel like this is an appropriate level of first intervention for someone who has never had fertility treatment, and while I know I don't have all the time in the world, my FSH does at least seem to be holding steady enough (down from 11 in March to 8.9 in June) that 2 months hopefully won't be the end of the world.
Plus, I have a feeling McIrish is right about the insurance. DH doesn't have MFI. His SA was good. We didn't get the most complete report on that available, but we had no trouble at all conceiving DD, and she's only one. I doubt he's just...developed it...in that time frame!
Anyway, thank you all so much for weighing in. It was a hard decision, and your support really helps. You guys are awesome!
ETA: DH is calmer about the twins thing. We both still hope it doesn't happen, but we'll deal with it (and be delighted to have them both, obviously) if it does.
Me: 41, DH: 45
DD, 6/15/2013
TTC #2 beginning January 2014
AMH 1.05; FSH range 7-11
July 2014: IUI #1. Follistim + Pregnyl. 2 follicles--BFN
September 2014: IUI #2. Follistim + Pregnyl + Ganirelix + Crinone. 4(?) follicles--BFN
October 2014: IUI #3. More Follistim + More Ganirelix + Pregnyl + Crinone. 4 follicles--BFP! Beta #1=10 Beta #2=33 Beta #3=97 Beta #4=158. M/C 11/1/14
December 2014: IVF #1. Microdose Lupron protocol. 9R, 9M, 9F. 3 5-day blasts transferred 12/15. BFFN.
August 2015: IVF #3. 14R, 13M, 11F. Froze 5 blasts for CCS testing. 3 normals. FET planned for 10/2015.
My Ovulation Chart
FYI - the time I did get pregnant, I had 4 viable follicles. Only one took.
TTC#1 since June 2012
Dx: Unexplained Infertility / AMA
BFP after 4th IUI cycle with Gonal F + Ovidrel on March 2014 | EDD 12/7/14 | MMC on 4/14/14
IUI#5 with Gonal F and Ovidrel trigger on 6/6 - BFN
On to IVF #1 with a new RE. Started Gonal F and Menopur on 8/15. Added Ganirelix on 8/24. Trigger on 8/26 for ER on 8/28. 8R 7M 3F. Transferred all 3 on 8/31. BFP on 9/11 | EDD 5/20/15 - Beta #1: 56.7. Beta #2: 97. Beta #3: 1148. Beta #4: 3559. Beta #4: 7678. MMC confirmed on 10/13. D&C on 10/14 at 9w. Confirmed male with Trisomy 14.
On to IVF #2 in March. CCS Testing on 2 embies. No go. Waiting to start IVF #3 in July. Surprise BFP on 6/14! EDD - 2/20/16 - Beta #1: 121.4. Beta #2: 236.4. Beta #3: 2014.
My BFP Chart
Me: 41, DH: 45
DD, 6/15/2013
TTC #2 beginning January 2014
AMH 1.05; FSH range 7-11
July 2014: IUI #1. Follistim + Pregnyl. 2 follicles--BFN
September 2014: IUI #2. Follistim + Pregnyl + Ganirelix + Crinone. 4(?) follicles--BFN
October 2014: IUI #3. More Follistim + More Ganirelix + Pregnyl + Crinone. 4 follicles--BFP! Beta #1=10 Beta #2=33 Beta #3=97 Beta #4=158. M/C 11/1/14
December 2014: IVF #1. Microdose Lupron protocol. 9R, 9M, 9F. 3 5-day blasts transferred 12/15. BFFN.
August 2015: IVF #3. 14R, 13M, 11F. Froze 5 blasts for CCS testing. 3 normals. FET planned for 10/2015.
My Ovulation Chart
DH: 45
BFP #1 3/19/14 EDD 11/29/14 MMC D&C 4/24/14
BFP #2 12/4/14 Beta #1 218 at 12dpo Beta #2 1055 at 16dpo
Saw heartbeat 12/29. Please be a rainbow.
All welcome