Trouble TTC

How many iui cycles?

I know it's different for everyone depending on the circumstances but I was just wondering what that magic number is for most ppl? I'm about to head into #3 after a short break and if this is a BFN I'm unsure what step to take next. We are dealing with MFI and my RE is hopeful but isn't persuasive either way, I'm just looking to see what others are planning/doing.
Thanks in advance
Married July 2 2011
Not trying Not preventing since 2011
Me: Ovulate on my own (but poorly) DH: Low count and poor motility
Oct 2013 Uterine polyp removed
Feb 2014 First round Ferama, trigger and IUI...BFN
March 2014 Second round Ferama, trigger and iui
Waiting....
Trying to Conceive Ticker

Re: How many iui cycles?

  • meld42meld42 member
    From what I've read, the first 4 IUIs have relatively the same likelihood of resulting in pregnancy. So, for us, we've decided after 4 we need to talk to our doctor's and see if there's something realatively fixable that they learned during the past 4 iuis, and if there's nothing fixable then we're onto IVF.

    I'd take a look at your insurance coverage, your health situation, and what's going on with you and your DH, you could probably come up with a little formula on how many IUIs make sense before moving onto your next steps. 
  • We are unexplained and OOP, we opted to do 4 IUIs before we moved on to IVF.  The studies I read showed that there are good rates for success in the first 4 IUIs, ok numbers for #5 &6, but after that, there is a serious case of diminishing returns.  I think it would also depend on how those cycles went.  For us, we did injects and B2B IUIs, had lots of follies and great SAs so we felt like we really gave it a fair shot.  Good luck with #3!
                                                  *********************SIGGY WARNING*************************
                                        May 14 Siggy                                             
    TTC #1 since June 2012.  DX: Unexplained Infertility.  Me: Hypothyroid
    3 Failed Femara + TI cycles and 4 Failed Injects + B2B IUI cycles
    Cycle 23: IVF#1 CoQ10 + Lupron + Puregon = BFP!!
    Beta #1: 199   Beta #2: 800+   It's TWINS!  EDD: Feb 19, 2015
    Team Purple!!!!
    L & E arrived early on January 5, 2015!!
    ~~~All are welcome!~~~

    BabyFruit Ticker
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  • I don't have an answer but my RE said we move on to IVF after 3.

    Maybe this helps: My RE said regular people w/o problems have a 20% chance getting pregnant with sex every cycle, and IUI has about a 10% chance each cycle.

    Me: 30   DH: 29
    TTC since 2010
    Oct. 2012 HSG: One blocked tube, one clear
    Oct. 2012 U/S: All good
    March 2014 SA: Flying Colors

    April  2014: Met our RE/Got our plan!
    May 2014: laparoscopy/hysteroscopy removed stage II endometriosis
    June 2014: IUI w/100mg Clomid (BFN)
    July 2014: IUI w/100mg Clomid (BFN)
    August 2014: IUI w/100mg Clomid (BFP!)
    September 2014: Beta 1 at 14 DPIUI: 100
    September 2014 Beta 2 at 16 DPIUI: 239
    September 2014: Beta 3 at 23 DPIUI: 3,159
    U/S 9/26: One healthy baby! Measuring 1 day ahead and a FHR of 119 @ 6W4D (EDD May 18)
    U/S 10/26 (first OBGYN visit): Measuring 1 day behind and a FHR of 160 @ 8 weeks. Looks like an upside-down Teddy Graham!


    image

    BabyFruit Ticker
    Pregnancy Ticker
  • I'm on my 5th IUI cycle now.  If this cycle fails, I'm done trying for the time being. 
  • ky29ky29 member
    My RE suggests moving on after 3, but he leaves it up to us.  We did 3, took a break and now we are doing our 4th and final.

    image
    TTC since March 2012
    DX: MFI (4% motility)

    Cycle 13: Natural cycle w/ HSG test = BFP
    Identical twins! 
    Lost my angel boys at 10.5 weeks

    Cycle 14-16: Natural Cycles = BFN
    Cycle 17: Follistim + Trigger + IUI = BFN
    Cycle 18: Natural Cycle = BFN
    Cycle 19: Follistim + Trigger +IUI#2
    Polyp found: SIS 11/11 - hysteroscopy 11/14
    Cycle 20: Follistim + IUI#2 = BFFN
    Cycle 21: Follistim (adj. dosage) + IUI#3 TI  = BFN
    IUI cancelled due to weather
    Cycle 22: Follistim + IUI#3.1 = BFN

    Cycle 23: treatment break, IVF consult
    Cycle 24 - 26: natural cycle w/ acupuncture + Chinese herbs = BFN
    Cycle 27: Follistim + IUI#4 = BFFN
    Natural Cycles until IVF
    Cycle 30: IVF#1 - Starting with Menopur + Follistim + Ganirelix
    17 retrieved, 12 fertilized, 5dt w/ 2 blasts, 5 frosties

    Betas:  #1-156(9dp5dt), #2-1200(13dp5) #3-6112(17dp5)
    Ultrasound #1 10/6: 1 bean!
    TEAM BLUE!

    My Chart
    ~~ALL WELCOME~~

    BabyFruit Ticker
  • We did 6 because that's how many insurance covered.
    Married 8/6/2011 Me (26) DH (33) SA normal,HSG clear TTC since August 2011 7/2012 50mg Clomid+Trigger+IUI+progesterone =BFN 8/2012 100mg Clomid+estrogen+Trigger+IUI+progestrone=BFN 10/2012 100mg clomid+Gonal+Lupron+Trigger+Progestrone+IUI=BFP but ectopic.
  • Our RE recommended doing 3 and that after that the chances of success weren't as high and we would be better off moving to IVF.

    Not sure how our insurance is going deal with that, we are thankfully covered for both, and while our RE's office has worked for a long time with our insurance company, I am hoping they don't require 6 IUI's before moving on, since by the time we do get to start an IVF cycle we'd have been trying for almost 2 years and I'd really just like to not do anymore IUI's.  I find them more painful.  We did IVM and I was an egg donor before, so retrievals don't bother me and the transfer during IVM didn't bother me, but man, and I am sore after an IUI.

    We did injects this last cycle, and I was in the RE's office 4 days in a row for monitoring.  6 trips out there for this IUI cycle.  I have progesterone tomorrow and then beta if don't get my period...so ug, lots of trips this time. 

    Me: 34, DH: 32
    TTC Since September 2012
    Dx-PCOS, Anovulation, highly irregular cycles
    March 2013 Comid 50 mg+ TI #1: BFN
    April 2013 Clomid mg + TI #2: BFN
    IVM#1 Aug 2012: BFN
    20 FEB 2014:  CP
    IUI #1 Clomid 100mg  24 FEB 2014: BFN

    IUI #2 Clomid 100mg  21 MAR 2014: BFN

    IUI#3 Follistim & trigger 21 May 2014: BFN

    IVF #1 Follistim & Menopur: 14R, 9M, 7F, transfered 2 day 3 8 cell embies

    Beta #1: 7/30: 41  Beta #2 8/1: 96   Beta #3 8/4: 796   EDD:4/9/15

      

     

     

    imageimageimage

    All Welcome 

  • I wouldn't do more than 3 or 4 cycles of the same thing (assuming I was having a good response. We planned to do 3 Clomid/IUI cycles and 3 inject/IUI cycles. However, my response to Clomid wasn't good, so we moved on sooner. My diagnosis is also related to ovulatory dysfunction, so our chances of success with an IUI are relatively high. If we had a different diagnosis, I would not be willing to try as many. If we have problems with overstimulating with injects, I would change my timeline too. It's all dependent on circumstances and flexible.
    **siggy warning**  **everyone welcome**

    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    DS- 11.07.02
    DSS- 6.26.04
    Married- 6.29.13
    TTC Again- Sept. 2013
    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    Test Results/Diagnosis- HSG & SA totally normal
    DX: 3/2014 Prolactinoma/Hyperprolactinemia- Started cabergoline 2/2014
    5/2014 Possible mild PCOS in addition to hyperprolactinemia??
    7/2014 Adding probable tubal factor to the diagnosis list
    9/2014 And now adding hypothyroid to the list- Started synthroid 9/2014
    Cycles 1-4 - Sept.-March- All Anovulatory 
    IUI #1 March/April-  Clomid 50mg + Clomid 100mg +Trigger + IUI #1 = BFN
     IUI #2 April/May-Clomid 100mg + Clomid 150mg + Trigger + IUI #2 + Endometrin=BFN
    IUI #3- June- Follistim 75iu + Trigger + IUI #3  Benched due to a 40 mm cyst. :-(
    IUI #3- July- Follistim 75iu + Trigger + IUI #3 + Endometrin = BFP! on 7/25/14
    Slowly rising betas - Ectopic suspected on 8/8/14 & confirmed on 8/11/14
    Methotrexate on 8/12/14 -HCG negative on 9/2/14
    IVF #1- November- Antagonist protocol: 11/1: start stims, 200iu of Follistim; 11/12 ER 17R/14M/14F; 11/17 5 day transfer of two blasts, 2 blasts and 2 expanding morulas frozen; 11/22 BFP!! (On FRER at 5dp5dt)
    Betas: 9dp5dt 205, 11dp5dt 497, 14dp5dt 1,709
    u/s at 5w0d- 1 sac; u/s at 6w0d 1 baby with heartbeat, another sac without a heartbeat
    image


  •  After 3 Clomid cycles with IUI and one Letrozole cycle that was switched TI, the RE had us schedule a WTF appointment.  In the meantime, we are in another Letrozole cycle for IUI #4.

    When we scheduled the WTF appointment, the nurse mentioned that the RE will likely suggest injects (+ IUI) or IVF.
    ________
    ME: 34, Atypical PCOS (lean, no O without meds) + unexplained; DH: 33, mildly low motility
    09/2012: Start TTC after stopping NuvaRing.  No cycles seemed to occur.
    01/2013 - 05/2013: Tried Provera to "jumpstart" cycles. No luck.
    12/2013-
    01/2014: Clomid 50mg - no big follies, stepped to 100mg; One mature follie, Ovidrel (HCG trigger), IUI #1 completed - BFN
    02/2014: Clomid 100mg;
    One mature follie, Ovidrel trigger, IUI #2 completed, Crinone - BFN
    03/2014: Clomid 100mg -
    no big follies on 1st round, 2nd round prescribed; One mature follie, Ovidrel, IUI #3 completed, Crinone - BFN
    04/2014-05/2014: Letrozole 5mg + Ovidrel HG to prep for IUI #4 switched to TI, Crinone - BFN
    05/2014-06/2014: Letrozole 5mg; one mature follie,
    Ovidrel, IUI #4.1 completed, Crinone - BFN
    07/2014-08/2014: Letrozole 5mg; one mature follie,
    Ovidrel, IUI #5 completed, Crinone - BFN
    09/2014-10/2014: IVF Prep - Insurance requires IUI #6;
    Letrozole 5mg - no big follies 1st round, 2nd round prescribed; IUI #6, Crinone - BFN
    11/2014: "Break" - Letrozole 5mg to cycle before prepping for IVF - successfully O'ed, but BFN
    12/2014: Extending 'break' one more Letrozole-only TI cycle for mental health break - BFN
    01/2015-
    02/2015: Prep for IVF - BCP then Gonal-F, Ganirelex, Novarel trigger;  ER scheduled 2/11!
    http://www.fertilityfriend.com/home/4cf919
    PAIF/SAIF Welcome.
    December 3T Siggy Challenge: Favorite Holiday Movie
    image
  • Thanks for the input! My insurence covers a lifetime of $15,000 of coverage so I dont want to use to much of it on iui and have nothing left if I decide to go further. I may do a max of 4 iui and then explore out options afterward . So stressful !
    Married July 2 2011
    Not trying Not preventing since 2011
    Me: Ovulate on my own (but poorly) DH: Low count and poor motility
    Oct 2013 Uterine polyp removed
    Feb 2014 First round Ferama, trigger and IUI...BFN
    March 2014 Second round Ferama, trigger and iui
    Waiting....
    Trying to Conceive Ticker
  • We did 3. But we would have done 5-6 if the insurance covered the medication. The first three were with clomid and then the ovidrel shot. The next would have been with Gonal-F. I think it depends on the RE. He told us that if after 5 we did not get pregnant, we would probably need to start looking into something else. 

    ME: 37, unexplained, all tests normal, no blockage. I do have celiac disease though diag 2/09
    DH: 37, mildly low motility
    TTC since 1/2011 but not actively. Actively trying since 9/12.
    11/13: IUI #1, 50mg Clomid + Ovidrel = BFN
    12/13: IUI #2, 100mg Clomid + Ovidrel = BFN
    1/14: IUI #3, 150mg Clomid + Ovidrel = BFN
    Taking a break due surgery on a torn ACL and now no insurance coverage for injectibles. 
  • We did 6 and now are moving on to ivf. That's the number me and my husband came up with.
  • I'm on number two and I don't mind trying four to six as long as I was responding well and it was just about the numbers game. If my RE changed his thoughts on my problem, then I'd go for IVF.

    ME:      36, on BC since 1996,  irregular periods.   HUBS:      37, healthy

    2001—meet.  2005—marry.  2006—Furbaby is born. 

    On BC till end of 2009.  2010 NTNP.   

    New Year’s Eve 2010—BFP?! January 13, 2011—early loss, HCG peaked at 324, no D&C needed.

    +++++

    Feb 2011-Nov 2012—NTNP 

    Dec 2012 --present (TTC 20 months) Not even a hint of a BFP

    Me:  BW, U/S, HSG, HSN normal.  AMH 2.33.  Hubs: SA normal 

    +++++

    April 2014--IUI #1 Clomid 100 4-8 Follistim 150 9-14, 5 mature follies at trigger, Peak E2 5/5 1100, BFN 

    May 2014 ---IUI#2 Clomid 100 3-7 Follistim 150 8-13, 3 mature follies at trigger, Peak E2 6/6 547, BFN

    June 2014--IUI#3 Follistim 150/225 3-15, 3-5 mature follies at trigger, Peak E2 7/11 1450, BFN

    July 2014--IUI#4 Follistim 225 2-12, 3 mature follies at trigger, Peak E2 8/12 841, BFN

    Breaking till after Christmas, then IVF...taking 4000 mgs daily Inositol and Melatonin 3mg


  • CML11CML11 member
    I'm doing my second one this week, I've been on the fence on whether we will do a third or move onto IVF. Hopefully this IUI is the lucky cycle and I won't have to worry about it!
  • We did 4, two unmedicated cycle and 2 on clomid. All BFN so we are moving on to IVF. Our insurance covers part of IUI but not IVF. 
    Me: 38, DH: 41
    TTC#2 since Feb 2013
    10/13: 1st IUI, BFN
    02/14: 2nd IUI, BFN
    03/14: HSG done, found out right tube is slightly blocked
    04/14: 3rd IUI, BFN
    05/14: 4th IUI, BFN
    07/14: IVF no. 1, BFN
    11/14: IVF no. 2, BFP



    Pregnancy Ticker
  • So far I'm not overstimming so I think we would do 3-6 before taking a break depending on how I'm feeling. we're in the middle of IUI #2 right now....depends what my RE is saying at that point I guess and how long until my DH deploys.

    Lilypie Angel and Memorial tickers

    TTC: Started May 2012
    Bloodwork - potential ovulation issue which seemed to be fixed by clomid.
    SA - Mot (36%) and count low 9.3 mil (updated) 
    HSG - Oct 16 2013 - came back clear
    Clomid #1 - Nov. 2013 - BFN
    BFP#1 =  Clomid #2, Dec. 2013 - EDD 9.9.14 Loss Jan 9
    Femara #1 + Trigger (2/21) Feb. 2014 +ruptured ovarian cyst - BFN
    SIS clear
    April 2014: 50IU Follistim CD3-CD9 + 25IU CD10-CD13+CD13 trigger 1 mature follie= BFN
    IUI #1: May 2014 50IU Follistim + trigger + IUI = BFN
    IUI #2: June 2014 50IU Follistim + IUI (3 mil sperm)=  BFN
    TI #2: June 2014 50IU Follistim  + Trigger = BFN
    BFP#2 = IUI# 3: Aug 2014 75IU Follistim+ Trigger + IUI (2 mil sperm) EDD May 15

    BabyFruit Ticker


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     Love bugs unite!
    Daisypath Anniversary tickers

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