Menopur or Menopure (?) solution to the burning sting and pain!

isano

I didn't have any pain with the 10 unit or 5 unit lupron (just itching), nor with the super easy to use follistim pen 75 unit injection. The menopur injection burned like one of the worst pains of my life. I heard it was going to sting but was in no way ready for what I felt. The 75 units of menopur + 1cc of saline dissolved together immediately and was at room temperature. We waited about 5 minutes prior to injecting. We didn't wait for the alcohol to dry 100% but it wasn't sopping wet either. Normally it was a non-issue with the daily lupron injections. I have heard the menopur pain varies for people. Mine was injected at a 45 degree angle into some belly fat. The pain was a burning, shooting sting that is similar to a general anesthesia injection but 10x worse (for me).

Since the pain was so intolerable, I called both my doctor as well as the on-call nurse from the specialty pharmacy for any tips. The nurse at my doctor's office said she wasn't sure reducing the 1cc to half would do anything because she wasn't sure if the sting occurs from. The nurse from the specialty pharmacy said that she has heard women have had success in reducing pain by using 1/2 a cc with the 75 units of menopur. She also suggested ice and confirmed that a 90 degree injection angle is ideal. She said belly fat would be less painful than the outer thigh injection and icing the area 10 minutes before could possibly help.

Night and day difference on the second night since I did the following:

Let the menopur mixture sit for 15 minutes before injecting
ice the area 10 minutes before injecting
allow alcohol to completely dry before puncturing the skin with the needle
inject only 1/2cc instead of 1 cc
ensure the injection is done much slower
massaging the area after injection

With all of the above taken into account, my pain was not that far off from a flu shot injection. I suppose this solution doesn't work for everyone but I wanted to share because I feel so much better with the info I got. I'm not a doctor and its important to double check with a medical pro before changing up anything even if its just the liquid solution for mixing.

Good luck ladies!

LundleBean

I'm sorry it stung so badly.  Glad you found a solution that worked for you. In my experience, it stung much less by the end of my cycle.  Of 3 different injections at once, the menopur did suck the most in the beginning and caused the BIGGEST bruises, but like I said, wasn't bad by the end.

I did make the mistake of not drying the alcohol-swabbed area before my very first lupron injection; BIG mistake.

pblge

I'm using Menopur for the first time starting in about a week. Thanks for these tips!

tptbabe

I found that letting Luveris (similar to Menopur) sit for awhile definitely helped with the burning! The first day was the worst, but it's been getting better! Glad you're finding the same

Irishlove16

The trick is to inject very very slowly!!! That was the trick that worked for me! And I iced the area beforehand which I did with all my shots!

dp21

Slow is the way to go!

Sha259

I've been taking 225iu Bravelle and 75iu Menopur, all reconstituted in 1cc NaCl. I have not had too much trouble with the burning, though it does sting a bit, I also found that injecting at 90 degrees and SLOWLY works best for me. I take a deep breath, stick, and slowly exhale as I inject. Been working great so far!

I hope it gets better for you.

Lady2010

Similar to pp - inject at 90 degrees, in the belly, and go slow.  I think it burned a little but it was nothing compared to the Cetrotide burn / itch.  Also I did have bruising with the Menopur.  

Good luck!

tarala

Slow is the way to go! I was on 175cc of menopur and it burned every single time going in. Centrotide made my skin all red and itchy. It's just all so much fun.

poohniki

Great tips. I remember it used to burn pretty bad. I am doing IM shots because I can't handle the bruising.