Trouble TTC

New to Follistim - questions!

Hello wonderful women of 3T... I just got back from my RE for my baseline ultrasound and discussed my upcoming protocol and I had a couple questions for those with Follistim experience.

1) My RE is putting me on 5 mg of letrozole for 5 days and then 100 iu of Follistim for 3 days.  That seems like... a lot.  Isn't Follistim pretty hardcore?  I sort of expected I'd start with 50 or 75 iu since I don't know how I'll react to it.  I'm nervous about over-stimming.

2) What's with the hormone draws?  Why do they do that for Follistim/IUI but not Clomid/IUI?  Shit's expensive.  $99 per test, and I had 3 tests taken (FSH, E2, and something else). 

Thank you for indulging my newb questions!!!  I'm happy to be in a new cycle, even if it's bleeding my bank account dry :P

Re: New to Follistim - questions!

  • I'm guessing they started you at 100iu of follistim bc of how you responded in previous cycles to the Clomid. I did Follistim my second IUI, after the first one w/ Clomid. They started me at 100iu as well and increased to 125iu for my last day to help my lining. The blood draws are probably to monitor your E2 in comparison to how many mature follicles you are showing. My RE only ever did one E2 draw on me, when I showed to have 4 almost mature follicles. I could be wrong on all this, but just wanted to share my input!  

    Good luck w/ everything!!

    ****siggy warning****

    Me 29/ DH 28
    DH- MFI (low count, 2-3% morph)

    IUI #1 January - Clomid, Ovidrel: BFN
    IUI #2 February - Letrozole, Follistim, Ovidrel: BFP 1st beta-25, 2nd beta-56, 3rd beta-45, miscarriage
    IUI #3 April - CD3 U/S 4-10. Letrozole, Follistim, Ovidrel CD11 - Cancelled.. TI w/5 follicles-BFN
    IUI #3.1 May - CD3 U/S 5-6, Follistim start 5-11 thru 5-17, u/s 5-18 3 mature w/ a close 4th, IUI 5-20 - BFP!
                 Beta #1 12dpo - 164 & progesterone - 89!, Beta #2 16 dpo - 1189, 5w3d - u/s shows TWINS!
                 6/19- u/s showed heartbeats! Baby A 111 & Baby B 118, both measuring 6w1d
                 7/3- Baby A hb 170, Baby B hb 166 - both measuring perfect.
                 7/18 - Baby A 165, Baby B 171 - both measuring right on track & moving all around!

    image

    Pregnancy Ticker

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  • Thank you!  Anyone know where I can find some scholarly research on the hormone levels?  That made me really curious.  When I do a Google search, though, I only see anecdotal evidence.  I'm kind of a nerd lol...
  • Yay!  Nerds unite!  Thanks, @NariaDreaming :)

  • My RE actually started me on 150 of follistim, based on no previous experience with any other medications

    4 Losses (2003, 2008, Apr 2012, & Oct 2012)
    All RPL and IF testing with multiple REs = normal

    5 IUIs = BFN

    All AL are welcome
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