Trouble TTC

First round of clomid / iui

Hello Ladies,

I introed awhile back, but I've been having issues participating on multiple boards. I hope it's still ok that I post here.

I had an appointment with my RE today for blood work, and an ultrasound. Everything looks good so I'll be taking 50mg clomid for 5 days starting tomorrow.

I will be going back mid cycle for more monitoring, but I'm being told to not have sex 3-5 days before I might get a lh surge. Is that normal? I thought we would be able to HIO the days leading up to O/IUI. I mean.. I guess it kind of makes sense, but I wanted to see what you guys thought.

I made sure to refresh my memory by reading the ttgp newbie blog's information on clomid.. I'm just feeling a little intimidated and overwhelmed. 

I might be looking for words of encouragement more than anything. 

I know I need to give support to get it so I'm really going to make more of an effort to be around rather than just poking my head in every now and then. I just usually don't know what to say when I'm here.

I hope y'all are having a wonderful evening.






Re: First round of clomid / iui

  • aves0708aves0708 member
    edited May 2014
    Hi!!  I am currently in my first medicated cycle with clomid/IUI,  and I was told that we needed to abstain for two days (no more than 5) before IUI if possible to make sure DH's counts were good. I found this to be way harder than it sounds lol. When I went in for my CD12 ultrasound, I had one 12mm follie that over the course of the  next couple days disappeared, and then finally another one popped up so we continued with monitoring and eventually got to IUI on CD21.  Because my body did not respond great to 50mg, we had no idea when the IUI would be, so we were doing our best to have sex/abstain within the right window.  Re was very understanding of this though, and we made it work.  Also, maybe because your RE doesn't know how you will respond, s/he wants to be cautious that you don't over respond, ovulate on your own and end up like kate gosselin.  

    Entering the world of medicated cycles was very overwhelming for me too, but being a regular part of this board helped so much.  I have learned so much while here, and that helped make this process a little less daunting.  Good luck with everything!!!

    ETA because apparently I can't think at night

    Me (29): Hashimoto's, CD3/7DPO bloodwork & ultrasound normal, HSG & SHG(x2) all clear
    DH (29): SA Perfect
    TTC Since Jan '13, First RE Appt Jan '14
    DX: Unspecified Ovarian Dysfunction, Long Cycles
    May '13 BFP, C/P 4w3d
    Apr '14:  50mg clomid + ovidrel + B2B IUI #1=BFP,  Natural M/C 6.5wks
    Aug '14: 50mg clomid + ovidrel + B2B IUI #2=BFN
    Oct '14: 100mg clomid + ovidrel + IUI#3 =BFN
    Nov 14: 100mg clomid + ovidrel + B2B IUI#4=slow response, bad lining, cancelled
    FU with RE, more bloodwork: Anticardiolipin +
    Dec 14: 5mg Letrozole+baby aspirin +ovidrel + B2B IUI#4.1=BFFN
    Jan '15: 5mg Letrozole +baby aspirin + ovidrel +B2B IUI #5= BFP!! 
    Beta #1 210  Beta #2 546


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  • @aves0708 - Thanks so much for responding! That makes a lot of sense :) I need to stop over-thinking this. 

    I really hope your IUI works for you!
  • jjgrl55jjgrl55 member
    No advice, just wanted to say I remember you from the TTGP board. Sorry we are both over here.


    image
    image
    Me & DH: 24 Married: 5/11
    Started TTC: 12/12 Testing Started: 5/14
    Dx: Irregular Ovulation, possible PCOS
    Treatment starting July '14: Letrozole + Trigger + TI
    Surprise natural BFP right before starting meds!!!!!- EDD 3/7/15

  • NotElsie said:
    @aves0708 - Thanks so much for responding! That makes a lot of sense :) I need to stop over-thinking this. 

    I really hope your IUI works for you!
    So I re read my response this morning and apparently I have a tough time typing at night.  It should read way harder than it sounds not easier lol

    Me (29): Hashimoto's, CD3/7DPO bloodwork & ultrasound normal, HSG & SHG(x2) all clear
    DH (29): SA Perfect
    TTC Since Jan '13, First RE Appt Jan '14
    DX: Unspecified Ovarian Dysfunction, Long Cycles
    May '13 BFP, C/P 4w3d
    Apr '14:  50mg clomid + ovidrel + B2B IUI #1=BFP,  Natural M/C 6.5wks
    Aug '14: 50mg clomid + ovidrel + B2B IUI #2=BFN
    Oct '14: 100mg clomid + ovidrel + IUI#3 =BFN
    Nov 14: 100mg clomid + ovidrel + B2B IUI#4=slow response, bad lining, cancelled
    FU with RE, more bloodwork: Anticardiolipin +
    Dec 14: 5mg Letrozole+baby aspirin +ovidrel + B2B IUI#4.1=BFFN
    Jan '15: 5mg Letrozole +baby aspirin + ovidrel +B2B IUI #5= BFP!! 
    Beta #1 210  Beta #2 546


  • When we had our IUI, we only had to abstain for 36 hours before the IUI. In fact, they specifically said to have sex at 36 hours ahead (the same night as the trigger).

    I'm wondering if they're trying to make sure you have good sperm counts on the IUI or if they don't want you to have sex when you're fertile in case you over-stimulate?? That I've never heard of. I'm assuming they're just thinking about your husband's counts though....
    **siggy warning**  **everyone welcome**

    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    DS- 11.07.02
    DSS- 6.26.04
    Married- 6.29.13
    TTC Again- Sept. 2013
    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    Test Results/Diagnosis- HSG & SA totally normal
    DX: 3/2014 Prolactinoma/Hyperprolactinemia- Started cabergoline 2/2014
    5/2014 Possible mild PCOS in addition to hyperprolactinemia??
    7/2014 Adding probable tubal factor to the diagnosis list
    9/2014 And now adding hypothyroid to the list- Started synthroid 9/2014
    Cycles 1-4 - Sept.-March- All Anovulatory 
    IUI #1 March/April-  Clomid 50mg + Clomid 100mg +Trigger + IUI #1 = BFN
     IUI #2 April/May-Clomid 100mg + Clomid 150mg + Trigger + IUI #2 + Endometrin=BFN
    IUI #3- June- Follistim 75iu + Trigger + IUI #3  Benched due to a 40 mm cyst. :-(
    IUI #3- July- Follistim 75iu + Trigger + IUI #3 + Endometrin = BFP! on 7/25/14
    Slowly rising betas - Ectopic suspected on 8/8/14 & confirmed on 8/11/14
    Methotrexate on 8/12/14 -HCG negative on 9/2/14
    IVF #1- November- Antagonist protocol: 11/1: start stims, 200iu of Follistim; 11/12 ER 17R/14M/14F; 11/17 5 day transfer of two blasts, 2 blasts and 2 expanding morulas frozen; 11/22 BFP!! (On FRER at 5dp5dt)
    Betas: 9dp5dt 205, 11dp5dt 497, 14dp5dt 1,709
    u/s at 5w0d- 1 sac; u/s at 6w0d 1 baby with heartbeat, another sac without a heartbeat
    image


  • I know for us, we were told to have sex the day of trigger and then the evening of the IUI and the day after IUI.  we also weren't limited on the number of says having sex leading up to trigger.   Each RE likes to follow different protocols and it can vary depending on your H's results as well.  Since DH's numbers were always good, we didn't have to abstain much.

    Me: 34, DH: 32
    TTC Since September 2012
    Dx-PCOS, Anovulation, highly irregular cycles
    March 2013 Comid 50 mg+ TI #1: BFN
    April 2013 Clomid mg + TI #2: BFN
    IVM#1 Aug 2012: BFN
    20 FEB 2014:  CP
    IUI #1 Clomid 100mg  24 FEB 2014: BFN

    IUI #2 Clomid 100mg  21 MAR 2014: BFN

    IUI#3 Follistim & trigger 21 May 2014: BFN

    IVF #1 Follistim & Menopur: 14R, 9M, 7F, transfered 2 day 3 8 cell embies

    Beta #1: 7/30: 41  Beta #2 8/1: 96   Beta #3 8/4: 796   EDD:4/9/15

      

     

     

    imageimageimage

    All Welcome 

  • It seems like everyone is given different instructions, and I think one possible downside of these boards is that I second guess everything if it doesn't follow what I typically see on here.

    I'm trying to be better about trusting my Dr., but I still tend to push back if the instructions don't seem right to me. So I guess that's my advice, don't be afraid to question the instructions you're given. Hopefully they are taking your history and test results into consideration and tweaking your schedule for a potentially better result.


    Married in 2006, TTC since Dec 2012
    Unexplained IF, Hypothyroidism

    IUI's 1 - 3: Femara + Ovidrel = BFN
    IUI's 4 - 5: Femara + Gonal F + Ovidrel = BFN

    IVF Jan 2015. 21R/18F/15 still growing on day 2
    Transferred two beautiful embies on day 2, beta 1/29

    image
  • Thank you all for your responses.

    I am being told to take the five days of clomid (cd5-cd9), and start testing for a surge on cd12. Once I have a surge I have to go in for a ultrasound, and possible IUI. That's when they would trigger me if they needed to.

    At least this is my understanding. Does that sound ok?

    I emailed my nurse yesterday asking monitoring questions, etc. I feel like I should ask some more questions, but I'm not really sure what else to ask.
  • NotElsie said:

    Thank you all for your responses.

    I am being told to take the five days of clomid (cd5-cd9), and start testing for a surge on cd12. Once I have a surge I have to go in for a ultrasound, and possible IUI. That's when they would trigger me if they needed to.

    At least this is my understanding. Does that sound ok?

    I emailed my nurse yesterday asking monitoring questions, etc. I feel like I should ask some more questions, but I'm not really sure what else to ask.

    This is what my RE told me at our consult for what our first medicated cycle would be.

    image
    Me: 30, PCOS-non IR, Annovulatory; DH: 31, SA normal :)
    Testing Completed! HSG Clear, Ovarian Reserve score 17, Elevated Testosterone, everything else normal so far
     Clomid 150mg + HCG + IUI #1 May/June 2014 (BFN)
    Clomid 150 mg + HCG + IUI #2 July 2014 (BFN)
    Femara 2.5mg + Estrace + HCG + IUI #3 Cancelled d/t no response
    Moving on to IVF with ICSI after break to lose weight.
    image

    My Ovulation Chart
  • Kam10Kam10 member
    Everyone has given you good advice, I just wanted to say good luck!

    *****Siggy Warning*****


    Toby        image

    Me:28 DH:28
    TTC #1 since Nov '12
    DX: Non-IR PCOS & Hypothyroidism 
    BFP: 11/7/13 EDD: 7/18/14 Ectopic Tubal Surgery 12/18 
    2/5 HSG all clear!
    Femara 5mg + Trigger + IUI #1- 5 = BFN
    IVF #1 - 17R 15M 11F - Transferred 1 beautiful hatching blast on 9/26    4 Frosties
    Beta (10dp5dt) = 166  Beta #2 (12dp5dt) = 284  Beta #3 (14dp5dt) = 471  Beta #4 (18dp5dt) = 2032
    EDD: 6/14/15
    ~All are welcome~

    BabyFruit Ticker

  • Thank you all so much, I feel a little bit better now :)
  • I can't give any info on the Clomid end of it but it seems to make since that they would want a good sample for the IUI from DH to use so maybe that is reasoning for the wait. Good luck and hope the IUI is a success! :)

    Trying to have baby #1 since April 2013

    DH SA March,May 2014 - Low motility and shape issues. On vitamins per RE to help

    Me testing April 3, 2014 - FSH and LH good, HSG showed blocked right tube

    April 29, 2014 - First RE appt., right tube needs to be removed and possibly left also if

    it's bad too. RE suggests going straight to IVF

    June 4, 2014 - LAP/HSC and unexpected endo. removed but tubes got to stay!

    June 13, 2014 - Post-Op appointment. We decide where to go next since main issue

    is MFI influenced. Trying naturally until decision... Repeat SA  in September. Aiming for IUI #1 November 2014.

    image

  • I guess my question would be what the plan is if you weren't getting a surge on your own. I started having ultrasounds every other week starting a day or two after I finished the Clomid. If I was just testing with OPKs I wouldn't have realized for quite a while that I wasn't responding to 50mg of Clomid.

    Is this a RE or an OB/GYN?
    **siggy warning**  **everyone welcome**

    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    DS- 11.07.02
    DSS- 6.26.04
    Married- 6.29.13
    TTC Again- Sept. 2013
    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    Test Results/Diagnosis- HSG & SA totally normal
    DX: 3/2014 Prolactinoma/Hyperprolactinemia- Started cabergoline 2/2014
    5/2014 Possible mild PCOS in addition to hyperprolactinemia??
    7/2014 Adding probable tubal factor to the diagnosis list
    9/2014 And now adding hypothyroid to the list- Started synthroid 9/2014
    Cycles 1-4 - Sept.-March- All Anovulatory 
    IUI #1 March/April-  Clomid 50mg + Clomid 100mg +Trigger + IUI #1 = BFN
     IUI #2 April/May-Clomid 100mg + Clomid 150mg + Trigger + IUI #2 + Endometrin=BFN
    IUI #3- June- Follistim 75iu + Trigger + IUI #3  Benched due to a 40 mm cyst. :-(
    IUI #3- July- Follistim 75iu + Trigger + IUI #3 + Endometrin = BFP! on 7/25/14
    Slowly rising betas - Ectopic suspected on 8/8/14 & confirmed on 8/11/14
    Methotrexate on 8/12/14 -HCG negative on 9/2/14
    IVF #1- November- Antagonist protocol: 11/1: start stims, 200iu of Follistim; 11/12 ER 17R/14M/14F; 11/17 5 day transfer of two blasts, 2 blasts and 2 expanding morulas frozen; 11/22 BFP!! (On FRER at 5dp5dt)
    Betas: 9dp5dt 205, 11dp5dt 497, 14dp5dt 1,709
    u/s at 5w0d- 1 sac; u/s at 6w0d 1 baby with heartbeat, another sac without a heartbeat
    image


  • Just popping in to say good luck with your first medicated cycle, lady!!  
                                                  *********************SIGGY WARNING*************************
                                        May 14 Siggy                                             
    TTC #1 since June 2012.  DX: Unexplained Infertility.  Me: Hypothyroid
    3 Failed Femara + TI cycles and 4 Failed Injects + B2B IUI cycles
    Cycle 23: IVF#1 CoQ10 + Lupron + Puregon = BFP!!
    Beta #1: 199   Beta #2: 800+   It's TWINS!  EDD: Feb 19, 2015
    Team Purple!!!!
    L & E arrived early on January 5, 2015!!
    ~~~All are welcome!~~~

    BabyFruit Ticker
  • I guess my question would be what the plan is if you weren't getting a surge on your own. I started having ultrasounds every other week starting a day or two after I finished the Clomid. If I was just testing with OPKs I wouldn't have realized for quite a while that I wasn't responding to 50mg of Clomid. Is this a RE or an OB/GYN?
    I am going to a RE. If I don't get a surge I think that is where the trigger comes in? It all depends on how my next ultrasound goes I guess.
  • lebradfordlebradford member
    edited May 2014
    NotElsie said:



    I guess my question would be what the plan is if you weren't getting a surge on your own. I started having ultrasounds every other week starting a day or two after I finished the Clomid. If I was just testing with OPKs I wouldn't have realized for quite a while that I wasn't responding to 50mg of Clomid.

    Is this a RE or an OB/GYN?

    I am going to a RE. If I don't get a surge I think that is where the trigger comes in? It all depends on how my next ultrasound goes I guess.
    -----

    Gotcha. Sorry, I think I might have misunderstood you before. I thought you meant the only ultrasound you'd get would be after your surge. If you're going for one shortly after finishing Clomid also, then they'll take care of any over- or under-response issues. :-)
    **siggy warning**  **everyone welcome**

    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    DS- 11.07.02
    DSS- 6.26.04
    Married- 6.29.13
    TTC Again- Sept. 2013
    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    Test Results/Diagnosis- HSG & SA totally normal
    DX: 3/2014 Prolactinoma/Hyperprolactinemia- Started cabergoline 2/2014
    5/2014 Possible mild PCOS in addition to hyperprolactinemia??
    7/2014 Adding probable tubal factor to the diagnosis list
    9/2014 And now adding hypothyroid to the list- Started synthroid 9/2014
    Cycles 1-4 - Sept.-March- All Anovulatory 
    IUI #1 March/April-  Clomid 50mg + Clomid 100mg +Trigger + IUI #1 = BFN
     IUI #2 April/May-Clomid 100mg + Clomid 150mg + Trigger + IUI #2 + Endometrin=BFN
    IUI #3- June- Follistim 75iu + Trigger + IUI #3  Benched due to a 40 mm cyst. :-(
    IUI #3- July- Follistim 75iu + Trigger + IUI #3 + Endometrin = BFP! on 7/25/14
    Slowly rising betas - Ectopic suspected on 8/8/14 & confirmed on 8/11/14
    Methotrexate on 8/12/14 -HCG negative on 9/2/14
    IVF #1- November- Antagonist protocol: 11/1: start stims, 200iu of Follistim; 11/12 ER 17R/14M/14F; 11/17 5 day transfer of two blasts, 2 blasts and 2 expanding morulas frozen; 11/22 BFP!! (On FRER at 5dp5dt)
    Betas: 9dp5dt 205, 11dp5dt 497, 14dp5dt 1,709
    u/s at 5w0d- 1 sac; u/s at 6w0d 1 baby with heartbeat, another sac without a heartbeat
    image


  • I guess my question would be what the plan is if you weren't getting a surge on your own. I started having ultrasounds every other week starting a day or two after I finished the Clomid. If I was just testing with OPKs I wouldn't have realized for quite a while that I wasn't responding to 50mg of Clomid. Is this a RE or an OB/GYN?
    I am going to a RE. If I don't get a surge I think that is where the trigger comes in? It all depends on how my next ultrasound goes I guess.
    ----- Gotcha. Sorry, I think I might have misunderstood you before. I thought you meant the only ultrasound you'd get would be after your surge. If you're going for one shortly after finishing Clomid also, then they'll take care of any over- or under-response issues. :-)
    This is exactly the reason why I posted. I'm so glad you said this.. they are NOT having me come in after finishing the meds / before the surge.

    I'm getting in touch with my nurse now. Thank you :)
  • NotElsie said:
    I guess my question would be what the plan is if you weren't getting a surge on your own. I started having ultrasounds every other week starting a day or two after I finished the Clomid. If I was just testing with OPKs I wouldn't have realized for quite a while that I wasn't responding to 50mg of Clomid. Is this a RE or an OB/GYN?
    I am going to a RE. If I don't get a surge I think that is where the trigger comes in? It all depends on how my next ultrasound goes I guess.
    ----- Gotcha. Sorry, I think I might have misunderstood you before. I thought you meant the only ultrasound you'd get would be after your surge. If you're going for one shortly after finishing Clomid also, then they'll take care of any over- or under-response issues. :-)
    This is exactly the reason why I posted. I'm so glad you said this.. they are NOT having me come in after finishing the meds / before the surge.

    I'm getting in touch with my nurse now. Thank you :)
    Oh, ok. Yeah, honestly, that would concern me some. I really don't want to unnecessarily add worry for anyone though. As for the trigger shot, I'm pretty sure that is only going to be helpful if you have a mature follicle ready to ovulate. If you don't have follicles growing, then a trigger is probably not going to result in a strong enough ovulation to get you pregnant. 

    It sounds like they're trying to do the least amount of ultrasounds possible. I get that to a point, because compared to other fertility drugs, Clomid isn't too crazy. And if they want you to come in once you get a surge to make sure you don't have too many follicles, that would probably be safe in terms of not too risky for multiples, especially if they are having you avoid sex before the ultrasound. However, I personally would rather have more frequent ultrasounds to know that I'm not over-responding and be able to have sex in the days leading up to ovulation in addition to my IUI to try to increase my chances of getting pregnant.

    Then there would be the issue of not knowing for quite a while if you are under-responding. If you aren't growing follicles, you aren't going to get a surge. If your doctor is on top of monitoring, you can take another round of Clomid within the same cycle (I did this my first IUI cycle), therefore not wasting an entire cycle. I'd be afraid that if they waited indefinitely for a surge and it didn't come, it might be too late to take another round of Clomid without waiting for a new cycle.

    It could be that they have good answers to these questions and concerns, and again, I really don't want to unnecessarily add worry to your plate, but maybe this will be helpful in terms of some things to think about if you're an over-thinker like me. ;-)

    Good luck though! I'll have my fingers crossed for you!
    **siggy warning**  **everyone welcome**

    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    DS- 11.07.02
    DSS- 6.26.04
    Married- 6.29.13
    TTC Again- Sept. 2013
    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    Test Results/Diagnosis- HSG & SA totally normal
    DX: 3/2014 Prolactinoma/Hyperprolactinemia- Started cabergoline 2/2014
    5/2014 Possible mild PCOS in addition to hyperprolactinemia??
    7/2014 Adding probable tubal factor to the diagnosis list
    9/2014 And now adding hypothyroid to the list- Started synthroid 9/2014
    Cycles 1-4 - Sept.-March- All Anovulatory 
    IUI #1 March/April-  Clomid 50mg + Clomid 100mg +Trigger + IUI #1 = BFN
     IUI #2 April/May-Clomid 100mg + Clomid 150mg + Trigger + IUI #2 + Endometrin=BFN
    IUI #3- June- Follistim 75iu + Trigger + IUI #3  Benched due to a 40 mm cyst. :-(
    IUI #3- July- Follistim 75iu + Trigger + IUI #3 + Endometrin = BFP! on 7/25/14
    Slowly rising betas - Ectopic suspected on 8/8/14 & confirmed on 8/11/14
    Methotrexate on 8/12/14 -HCG negative on 9/2/14
    IVF #1- November- Antagonist protocol: 11/1: start stims, 200iu of Follistim; 11/12 ER 17R/14M/14F; 11/17 5 day transfer of two blasts, 2 blasts and 2 expanding morulas frozen; 11/22 BFP!! (On FRER at 5dp5dt)
    Betas: 9dp5dt 205, 11dp5dt 497, 14dp5dt 1,709
    u/s at 5w0d- 1 sac; u/s at 6w0d 1 baby with heartbeat, another sac without a heartbeat
    image


  • lebradford  - Thanks for all the info! You have really helped things make sense.

    If I don't get a surge by a specific date they will have me come in to see what is going on. I just talked to my nurse about everything, and it's looking good :)
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