Harmony test

lcloffredo

I don't know too much about it but was wondering if anybody had it done and what your experience was with it. What was your reason, did insurance cover it, is it just a blood test, can they tell if your twins are identical? I want to know everything!

CaliCarly77

I did Maternit21 and really appreciated knowing that everything was perfect, it put my mind at ease. We chose to not find out the sex of the babies. Just so you know, if the result is "boy" then you either have b/b or b/g - the only certainty is g/g twins. If the result is YES that there is a trisomy, and your twins are not identical, then they will need to do an amnio to determine which twin(s) have the trisomy. Insurance covered it since I am over 35. I did it because I like to be as prepared for everything as possible, and know my options if there was, god forbid, a trisomy present. They can't tell you that your twins are identical with the trisomy text. 

basil2

We did it, and were glad to have the reassurance.  We had no trouble with insurance, but that probably varies.  Where I am, you have to see the geneticist to get it ordered.  It's just a simple blood test, but you should be aware that it takes approx 2 wks to get a result, and sometimes it comes back inconclusive (which means you can repeat it, but then it's another 2 weeks, and that can be nerve-wracking) (A coworker had a somewhat miserable experience a year or 2 ago- everything was fine in the end but it took forever to get the results.)  I was told they couldn't do sex at all for twins (though with a twin pregnancy you'll wind up with more than enough ultrasounds to find out the answer to that if you want it). 

jocie2581

Maternit21 was covered by insurance for me because the results of my quad screen came back with an elevated risk of Down syndrome (1:97). The test can detect if Y chromosome is present - meaning at least one is a boy.

Rannndi

We didn't and later we wished we would have.  Our doctor said that it wasn't necessary because my odds were so low.  Then later we found out that one of our girls have an Single Umbilical Artery which comes with a heightened risk of abnormalities and it was too late to do any testing.  It wouldn't have changed anything but it would have helped me prepare.  If we wanted to know now, we'd have to do an amnio.  At our 20 week A/S, everything looked great and there were no markers for anything being wrong in regard to chromosomes/trisomies, but there's still that slightly elevated risk for it.

lcloffredo

Thanks everybody, there is so much to think about!

Rannndi

car seat said: Rannndi said: We didn't and later we wished we would have.  Our doctor said that it wasn't necessary because my odds were so low.  Then later we found out that one of our girls have an Single Umbilical Artery which comes with a heightened risk of abnormalities and it was too late to do any testing.  It wouldn't have changed anything but it would have helped me prepare.  If we wanted to know now, we'd have to do an amnio.  At our 20 week A/S, everything looked great and there were no markers for anything being wrong in regard to chromosomes/trisomies, but there's still that slightly elevated risk for it. cf-DNA testing can be done as early as 10 weeks and then throughout the pregnancy. I think you must be thinking of the NT testing, which is different from Harmony or mat21 and can only be done between 11w-13w4d.


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All I know is the MFM told me there were no other tests that would be reliable enough at that point.  They said that I could do blood work for more DNA testing, but they aren't as reliable as they'd like them to be further in the pregnancy.  That's why mine only really suggested the amnio at that point.  I had already had the cf blood work done, but I didn't complete the rest.