Infertility

3dt vs 5dt

Is there a difference In success rates for 3 day transfer vs 5 day? Why do they make the decision to do one vs the other?

IVF #1 Oct 2013- cancelled 
IVF #2 Mar 2014- success.... baby girl born 11/28/14
FET #1 Mar 2016- baby boy due 12/16/16


Re: 3dt vs 5dt

  • All I really know if that 3 Day Embryos are still using mostly all your DNA and metabolism. On Day 5. Dh's DNA and metabolism are also taken into effect. So if you're worried about sperm quality- you have no way of knowing how the embryo will do when it is transferred on Day 3. By Day 5, the embryo should have its own DNA/Metabolism (which is combined from you and dh) so it could is usually a better indicator if it can last to day 6- knowing that its own system is working.
    ***WARNING***

    TTC Since 12/2008;  DH: 32, Azoospermia     me: 33, DX during IVF #4: Low AMH (Normal FSH) / SER due 
    to IVF Meds (causing failure to fertilize) Recent DX: Hashimoto's, Lupus Anticoagulant, White Blood Cell Disorder 
    High ANA, ATA, & APA, PAI-1 Heterozygous= blood clotting disorder; connective tissue disorder 
    IVF w/ ICSI #1 2/2011     IVF w/ ICSI #2 5/2011    IVF w/ ICSI #3 12/2012   *New RE* IVF w/ ICSI #4  5/2013
    IVF w/ ICSI #5 8/2013 (Natural Cycle- No drugs)- One follicle->one blast. CCS normal. FET 9/10- 6BB blast. m/c @ 5w
    IUI #1 12/23- BFN  IUI #2 Cancelled (ovulated during AF)  Prep:CoQ10 (300 mg); DHEA (25 mg); Melatonin (3 mg), Folgard 2.2, Metformin 500 2x, Levothyroxine 50mcg, Aspirin 81mg w/ calcium, B12,  Vit. D 4000 & Prenate Elite Daily; Cabergoline 1/2 pill 2x week-  Cycling: Estrace Priming; Prednisone 10mg, Lovenox 40mg 2x,  Femera & Menopur   
    IUI #2.1 6/30 & 7/1. 1st Beta: 90 (7/15); 2nd Beta: 226 (7/17); 3rd Beta: 766   EDD: 3/23/2015

       **ALL WELCOME**                                    My Blog 
    image
    image


  • From what I understand, 5dt is preferable because it allows the embryologist to pick the strongest embryo.

    @poohniki‌, your explanation gives me some peace of mind about our embryo situation. It's a little hard to explain why, but knowing that makes me feel better - I don't feel 100% to blame for all of this.
    **SIGGY WARNING**

    Me: 32 DH: 35  TTC#1 since March 2012
    Dx: Poor Embryo Quality, Arcuate Uterus, Poor Uterine Blood Flow, Mild Endo, 
           Protein S Deficiency, Sjorgen's Syndrome 

    IUI #1-5: BFN
    Laparoscopy & Hysteroscopy: minimal endo, partial septoplasty
    IVF #1: 10R/6M/6F ~ Day 3 ET = BFN
    IVF #2: 14R/9M/5F ~ transfer canceled ~ all embryos arrested at 1-2 cell stage
    IVF #3: 9R/5M/5F ~ 1 frosty!
    IVF #4 (FET #1): BFN

    IVF #5 (DE IVF #1 with Dr. KK protocol): Currently PREGNANT!!!!!!
    Synthroid + Prednisone + Metformin + Baby Aspirin + Supplements Galore = 15+ pills a day
    Lupron + Lovenox + Delestrogen + IVIG + B/W = 2-5 pokes a day
    19R, 17M, 17F - transferred two Grade A blasts 11/16, four frosties!!!
    Beta #1 11/24 (13dpo/8dp5dt) = 367 ~ Beta #2 11/26 (15dpo/10dp5dt) = 709
    Beta #3 11/29 (18dpo/13dp5dt) = 1,997 ~ Beta #4 12/1 (20dpo/15dp5dt) = 3,403

    imageimageimage

    My Blog: Running and Dreaming for Two ~ All are Welcome!
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  • Thanks for asking this @boyankl‌, you read my mind. And @poohniki‌ & @RunCC37‌ thanks for the explanation, we are MFI, so this gave me more insight into our planned cycle.
    *************WARNING CP mentioned***********
    TTC since 12/2012 Me: hypothyroid & egg issues
    DH: MFI
    IUI #1 BFN
    2nd treatment cycle: Clomid & TI BFN
    IUI #2 (injects) IUI BFN
    2/14 through 3/14 benched with a cyst
    IVF#1 CD1 came before beta. BFN. No frosties.
    Benched with cysts...
    IVF#2 beta moved up due to heavy bleeding 6dp5dt...beta was 11. beta#2 20.4! Beta#3 28 Chemical pregnancy :(
    Currently on BCPs with cysts, planning IVF#3 Everyone welcome!
    imageimage
    imageimage
  • @poohniki and @runcc37 thanks ladies, eagerly awaiting the call from the lab right now to determine if I transfer today or Tuesday.

    @Mozzarella13‌ good luck on your ET!

    IVF #1 Oct 2013- cancelled 
    IVF #2 Mar 2014- success.... baby girl born 11/28/14
    FET #1 Mar 2016- baby boy due 12/16/16


  • Good luck with your update today!

    dream 1 CAME TRUE 2.13.2010


     <dream 2> 12.2011


     2.10.12 : 4 weeks


    6.17.12 : 10 weeks


    10.10.12 : 4 weeks, 6 days


    12.13.12 : 9 weeks, 1 day


    4.6.13 : 4 weeks, 4 days


    10.27.13 : 5 weeks, 6 days


    4.2.14 (IVF #1) : 4 weeks, 1 day


    6.19.14 : IVF #2 Negative


     </dream 2>


     resolve.org


    AMA, Diminished Ovarian Reserve, heterozygous MTHFR


    "all it was was a fairytale and devotion to a dream"

    lyrics

    Image and video hosting by TinyPic
    ***All always welcome!!***

  • Just wanted you to know I'm thinking of you and wishing you best of luck!

     image

    BFP #1: 1/4/13, EDD 9/8/13, Missed M/C confirmed 2/8/13, Misoprostol

    2013: Three CPs w/ EDDs: EDD 2/10/14, EDD 3/24/14, EDD 6/24/14

    IVF/ICSI #1 (Antagonist) - Jan 2014- 19R, 14M, 11F, 3 penguins (6BB, 4BB, 6BC)  PGD tested- All Normal!

    IVF/ICSI #2 (Antagonist) - Feb 2014 - 23R, 11M, 10F, 1 penguin (3BB) - Another Normal!

    FET #1 - March 26, BFN

    FET #2- Beta #1 (9dp5dt) -332, Beta #2 (11dp5dt) -1027, EDD 1/30/2015, Missed M/C, D&C 6/19/14

    IVF/ICSI #3 (Lupron Down Reg) - Oct 2014 - 38R, 28M, 27F, 20 frozen on day 5, 16 normal penguins!!

    FET#3 - February 1, 2015, Prep begins 1/13

    All Welcome!

  • All i know is we did 2 5dt which resulted in BFN and got a bfp on our first 3dt. GL!
    image



    Me 28 DH 30

    After 4+ years TTC

    FET #2 = DS Madden Jeffery <3 July 29, 2014 <3
  • Good luck on Tuesday!
    *~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~
    Waited a long time, tried a lot of stuff, science made me a mom.
     Loss and IF veteran. Current mom of DS 5.5, DD 2, and sometimes DH 40. Due June 2021 with TWINS
  • Great news! Good luck on Tuesday!
    ***WARNING***

    TTC Since 12/2008;  DH: 32, Azoospermia     me: 33, DX during IVF #4: Low AMH (Normal FSH) / SER due 
    to IVF Meds (causing failure to fertilize) Recent DX: Hashimoto's, Lupus Anticoagulant, White Blood Cell Disorder 
    High ANA, ATA, & APA, PAI-1 Heterozygous= blood clotting disorder; connective tissue disorder 
    IVF w/ ICSI #1 2/2011     IVF w/ ICSI #2 5/2011    IVF w/ ICSI #3 12/2012   *New RE* IVF w/ ICSI #4  5/2013
    IVF w/ ICSI #5 8/2013 (Natural Cycle- No drugs)- One follicle->one blast. CCS normal. FET 9/10- 6BB blast. m/c @ 5w
    IUI #1 12/23- BFN  IUI #2 Cancelled (ovulated during AF)  Prep:CoQ10 (300 mg); DHEA (25 mg); Melatonin (3 mg), Folgard 2.2, Metformin 500 2x, Levothyroxine 50mcg, Aspirin 81mg w/ calcium, B12,  Vit. D 4000 & Prenate Elite Daily; Cabergoline 1/2 pill 2x week-  Cycling: Estrace Priming; Prednisone 10mg, Lovenox 40mg 2x,  Femera & Menopur   
    IUI #2.1 6/30 & 7/1. 1st Beta: 90 (7/15); 2nd Beta: 226 (7/17); 3rd Beta: 766   EDD: 3/23/2015

       **ALL WELCOME**                                    My Blog 
    image
    image


  • Tea+Tea+ member
    Good luck Tuesday! [:
    TTC Since 2012
    Me: Endo Stage IV (20+yrs) (who knew? Not me)
    MyLove: Pretty Ok. Low #s (i think) 
    IVF#1: No Eggs to Retrieve
    Taking time to ourselves
     Poor Responder will add COQ10 & DHEA next cycle
    **All Welcome**


    image



  • Best wishes for Tuesday.

    image
  • Good luck Tuesday!!
    *************WARNING CP mentioned***********
    TTC since 12/2012 Me: hypothyroid & egg issues
    DH: MFI
    IUI #1 BFN
    2nd treatment cycle: Clomid & TI BFN
    IUI #2 (injects) IUI BFN
    2/14 through 3/14 benched with a cyst
    IVF#1 CD1 came before beta. BFN. No frosties.
    Benched with cysts...
    IVF#2 beta moved up due to heavy bleeding 6dp5dt...beta was 11. beta#2 20.4! Beta#3 28 Chemical pregnancy :(
    Currently on BCPs with cysts, planning IVF#3 Everyone welcome!
    imageimage
    imageimage
  • Good Luck. The transfer is truly amazing
    ===siggy warning====
    Me: 40, DH: 42
    Diagnosis: PCOS
    TTC: May 2013
    TX: IUI #1 with Follistim. Canceled due to too many follicles (10 + that were large); BENCHED
    IVF #1 March 6. 14 eggs retrieved, 10 fertilized. 
    March 11, 4 eggs transferred.
    March 21 BFP  :) Beta #1 457, Beta #2 1350, Beta #3 9619. 
    Due Date November 27, 2014
    TEAM BLUE

  • Good luck! @poohniki, thanks for the great explanation!

    Me: 28, DH: 35
    DX: Severe MFI, AZFc Microdeletion
    TTC since August 2011
    IVF w/ ICSI 1: Dec. 2013 - BFN
    FET 1.2: Mar. 2014 - BFN
    FET 1.3: May 2014 - BFN
    FET 1.4: June 2014 - BFP
    Two little buns in the oven. 
    Bake until March 2015, little ones. 


    "Life will be clearer around me.
     Life will be more burdensome for me. 
    Life will be richer for me." 
    -Rudolf Steiner
  • From what we have heard from our RE, a book we reference, and web searches, some RE's think that it is more natural to transfer embryos at 3dt to let it progress naturally inside.  Most do seem to prefer the 5dt of blastocysts. 

    My 5dt is tomorrow and we were reading tonight that only 40% of fertilized eggs make it to the blastocyst phase.  By waiting two extra days and only transferring blastocycts, it weeds out the embryos that likely woudln't have made it.

    There have been many people on these boards lately that have mentioned going to 3dt because they only had about 1 or 2 embryos to work with.  At that point, there is no sense in waiting to choose the best. 

    Good luck!

    ***BFP and Loss Mentioned in Siggy***

    Me: 39 (PCOS)
    DH: 47 (slightly low volume...considered MFI)
    TTC since 11/2012
    10/2013:  IUI#1 BFN - 50mg clomid, two .75mg shots of Bravelle, ovidril trigger...1 follicle
    11/14/13: IUI#2 BFN - 50mg clomid, two .75 mg shots of Bravelle, ovidrill trigger..2 follicles

    IVF #1 w/ICSI:  ER 3/12/14; ET 3/17/14:  BFP!!!  Beta #1 3/31/14=1540;  Beta #2 4/2/14 =2551

    Twin A became an angel on 4/30/14 (8w6d)

    Twin B became an angel on 5/21/14 (11w6d)

    D&C 5/23/14

    FET#1 - 9/2/14 - BFP!!! Beta #1 (9/15): 926.  Beta #2 (9/17): 1946.

    MC -9/20/14
    FET#2 - 4/20/15 - BFP!!! Beta #1 (5/4): 1277.  Beta #2 (5/6): 2817.  US#5 -153 heartbeat.
    Due Date: January 6, 2016
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