Hi Folks,
I originally posted here about 4 weeks ago crossing over from Infertility to ask your input on the possibility that my low E2 levels would catch up enough. Thanks for all the advice!
My partner
@Manada and I are 5 weeks 1 day pregnant. She has DOR and I have severe stage IV endo. We did six failed IUI cycles with Manada (femara, clomid, injectables, etc) before moving on to IVF. And I had my tubes out last June, so we didn't even get to try IUIs with me.
We did partner IVF (my eggs, her uterus) to get pregnant. Although our cycle did not go as well as hoped (details in signature) we did end up with 3 day 3 embryos. We transferred two and froze the third. We had a squinter at 6dp3dt. Our first beta (11dp3dt) was 110. Our second (13dp3dt) scared us because it didn't double (only 175). Our third was (15dp3dt) was an improved 348. And our fourth beta (today--19dp3dt) was 2222 and made us excited enough to intro here. (I assume Manada will intro soon).
We have a fifth beta on Friday and will have our first ultrasound next Wednesday or Thursday.
Thanks for the support you offered before we were even pregnant. I really hope we get to stay here for another 8 months!
IF brain and the residual stress of infertility is pretty intense for both of us, as I'm sure it is for many here, so I look forward to having a community of folks who get it.
Re: intro-- new here!
TTC since July 2011
BFP #1: 2/15/12-Ectopic/Mtx at 6 wks
BFP #2: 10/12/12-m/c at 5 wks.
Me: MTHFR, Low AMH (1.1), High NK cells and Antiphospholipid Antibodies.
IVF with ICSI in August 2013 brought us our babies. ER-9R, 7M, 4F w/ICSI ET of 2-Grade 2 blasts.
Dx shortened cervix, PTL, and preeclampsia during pregnancy. Lots of medications and 13 weeks of bedrest, babies were born healthy at 34w4d!
Jan-March '13 3 IUIs Clomid + Trigger = BFN
He's Here! Arrived 4/15/14!!!!
September 2015 - FET with remaining embryos
Twins! EDD: 6/14/15
PAIF/SAIF Everyone welcome!
June- Femara 7.5mg + Trigger + IUI = BFN August- Lap & Hysteroscopy = Blocked & Partially Blocked Tubes
September- Femara 5mg = CX - No Response on Left = BFN October- 100mg Clomid + Trigger + TI = BFN
IVF # 1: Stims 11/30 ER 12/12/12! (10R, 10M, 8F, 2T, 6 F) :: Beta #1- 176 c/p @ 4w4d
FET #1 February 26th :: Lost 4 to Thaw, Transferred 2 = BFFN
IVF # 2 Stims 5/10 ER 5/21 (15R, 13M, 13F, 2T, 7F- 6d3 & 1d5) :: Beta # 1- 15 c/p @ 4w
FET #2.2 Scheduled for September 20th
2 Thawed, 2 Transferred! Beta #1- 96, Beta #2 906! :: EDD June 10th
2015- 2 failed FET. We are done
SURPRISE! BFP 8/8/16 EDD 4/1/17
Me: 42. DH: 46.
1st Pregnancy: MC, 11/19/00.
2nd Pregnancy: DS born 04/10/06.
3rd Pregnancy: CP, 03/11.
4th Pregnancy: MMC, D&C 11/30/11, Genetic testing revealed Trisomy 4.
5th Pregnancy: Ectopic, 2 doses of Methotrexate unsuccessful, surgery 4/10/12, right tube removed.
Tried Letrozole January 2013-July 2013 (including 2 IUIs), all BFN. After 2 1/2 years of trying for child #2, decided to "give up" after July cycle, based on AMA.
August 16, 2013: BFP our first month of "not trying!" Still in shock. Beta #1 (14dpo): 183. Beta #2 (17dpo): 611. Ultrasound 8/30/13: baby measured 6 weeks, 1 day, heart rate of 118 bpm!
Ultrasound 9/13/13: 8 weeks, heart rate of 176!
Baby is due 4/26/14
My BLOG: www.ivfbabyquest.wordpress.com -Update - old blog.
PAIF/SAIF Welcome!
Me: 42, Hubby: 35, TTC since Jan 2010. Dx: DOR due to advanced maternal age. Also: Hypothyroidism (100mcg Levothyroxin). Positive for MTHFR (hetero-C677T), Factor V Leiden, and Fragile X (on DH side). Taking pre-natal vitamins.
First natural PG 9/27/11; mc: 1/20/12
First RE visit: 8/8/12, Saline Sonogram: 8/28/12, IVF injection class: 10/11/12, add FaBB Tab for FVL, +Vitamin D.
IVF #1: 10/17/12 Baseline: FSH- 9.4, E2- 24, LH- 3.7, Prog- 0.3 The u/s showed 6 follicles in my right & 9 in my left. Rx: 150 Bravelle & 150 Menopur SQ nightly. 10/21/12: Add Ganirelix SQ every morning.
ER 10/28/12: 13 Retreived. 7 Mature. 6 Fertilized. 5 Made it to PGS. ET 11/2/12: CANCELED. All 5 came back from PGS as having "severe abnormalities."
IVF #2: 1/7/13 Baseline: FSH- 8.8, 4 follicles in my right & 6 in my left. Rx: 150 Bravelle & 150 Menopur SQ nightly. 1/11/13: Add Ganirelix SQ every morning. hCG Trigger 1/16/13
ER 1/18/13: 9 Retrieved. 5 Mature. 5 Fertilized. 2 Made it to PGS. ET 1/23/13: CANCELED. All embryos (he even sent the ones not growing) came back from PGS as having "multiple severe abnormalities."
IVF #3: NEW RE! 3/1/13 Baseline: FSH- 9.6, E2- 61, Prog- 0.94, 3 follicles in my right & 4 in my left. Rx: 150 Bravelle& 150 Menopur SQ in PM. 3/7/13: Add Ganirelix SQ in AM. hCG Trigger 3/9/13 SQ.
ER 3/11/13: 6R, 2M, 2F. Day 3: one 8 cell, grade 0. Five day ET 3/16/13: one early blast, grade Fair. 3/24/13 AF came a day before beta. BFN
IVF #4: (Added acupuncture to this cycle.) 3/25/13 WTF & Baseline: FSH-11.8, E2- 56, Prog- 0.84 3/26/13 Start stims. 3/30/13 u/s: 5 follicles in my right & 4 in my left. Rx: 225 Bravelle& 225 Menopur SQ in PM. 3/31/13 Add Ganirelix SQ in AM.hCG Trigger 4/3/13 SQ.
ER 4/5/13: 5R, 3M, 3F naturally. Day 3: two 8 cell, grade 0, one 8 cell, grade 2 (Scale 0-best to 3-worst). Five day ET 4/10/13: two blastocysts (the 3rd stopped growing.) Beta 4/18/13: 2.5 BFFN. RE recommends we stop trying and focus on living childless, due to the extremely poor quality of my eggs.
***Decided to stop trying and live CFNBC. I couldn't adjust. So, six months later...
IVF #5: Changed RE. Going to one of the big name clinics now. OWDU: 10/29/13. Update: HORRIBLE experience. Disgusted and distraught at their complete unprofessionalism and how much money and precious time they cost us. Sickening. Have now changed RE again. New Patient appt. 1/30/14.
BFP! Out of nowhere, I got KU the old fashioned way! POAS 1/26/14 - Positive! FDLM 12/30/13. Beta #1 16dpo= 373. Beta #2 18dpo= 801. EDD 10/6/14
2/4/14 1st U/S revealed a 5wk2day sac but no fetal pole. Started 200mgs of progesterone suppositories daily
2/11/14 2nd U/S revealed a perfect 6wk1day "diamond ring" embryo with a beating heart! 138bpm! Add 1mg folic acid and 40mg Lovenox
2/25/14 3rd U/S: perfect 8w1d embryo, 178bpm. 3/6 start spotting. 3/11 10w1d U/S shows no heartbeat. Scheduling D&C. The Stork has forsaken me again.
IVF #5.2: New in-state RE. Supplement priming for 1.5 cycles prior to start of cycle, including DHEA 50mg (stopped 5/15), CoQ10 200mg 2x/day, L-Arginine- 1000mg 2x/day (stopped 6/5 due to cold sore!), myo-inositol- 2g 2x/day, melatonin- 3mg, and Neevo (prenatal for MTHFR).
5/16/14 Day 2 bw cycle prior: FSH- 12.22, E2- 38.37, Prog- 1.35, LH- 9.46. 6/2/14 Day 19 bw: Prog- 23
6/12/14 Baseline: E2- 122.7, Prog- 0.4. 5 follicles in left, 4 follicles in right. Start stims: 375IU Follistim & 150IU Menopur. 6/19 Increase Follistim to 425IU, Menopur still 150IU. 6/18 add Ganirelix. 6/23 Ovidrel trigger SQ. 6/25 ER: 8R, 8M, 5F naturally. Start Medrol & Doxy. 6/26 Start Endometrin. 7/2 Start Lovenox.
7/8/14 Beta= 137.4 BFP!!! (My first from IVF!) E2- 1109, Prog- >60. Stop CoQ10, myo-inositol, and melatonin. 7/9 2nd Beta= 281.4. TSH- 2.70. Increasing Synthroid to 100mcg daily. 7/24 6w3d u/s measured 6w3d, hb: 121bmp! 8/5 8w1d u/s measured 8w3d, hb: 164bpm! Graduated from RE to OB. Now I just need to find an OB!
EDD 3/18/15!
************ Signature/Ticker Warning ************

Me (32) DH (36) - Finding our way to baby #1
Me: POF/DOR - AMH <0.16, heterozygous c677t MTHFR, insulin resistant and gluten intolerant
DH: Severe MFI
12/2/11 - IUI #1- BFN
8/1/12 - IVF #1 - Zero response from max stims (600iu intramuscularly)
My ovaries are just for decoration
12/6/12 - Adopted five embryos that had been frozen for over ten years!
2/11/13 - DEmbryo FET #1 Thawed four, sadly two didn't survive. Transferred two beautiful blasts.
2/16/13 - First BFP of my life @ 6dp5dt! EDD 10/30/13
3/27/13 - After beta and u/s hell, no heartbeat ever detected. D&C at 9w1d.
6/5/13 - Adopted four new embryos that had been frozen for seven years!
9/12/13 - DEmbryo FET #2. Thawed and transferred two beautiful blasts
9/17/13 - BFP @ 5dp6dt! EDD 05/31/14
9/29/13 - m/c @ 5w1d.
11/19/13 - DEmbryo FET #3. Thawed and transferred one blast from each batch. Wow!
11/23/13 - BFP @ 4dp6dt! EDD 8/7/13
Beta #1 @ 13dp6dt - 522 Beta #2 @ 16dp6dt - 1373
6w5d ultrasound showed one perfect baby with a beautiful heartbeat of 134bpm!
Snowflake baby is a girl!
Our beautiful Snowflake girl arrived on July 22, 2014!
My embryo adoption blog: Wishing on a Snowflake
TTC since Sept 2011, Unexplained IF
Oct 12 - Jan 14: 3 clomid/TI cycles, 2 hysteroscopies, 2 IUIs, 1 BFP (MMC @ 12w), 2 more IUIs
Feb 14: Gonal-f + IUI #5 = BFP! (EDD 11/4/14)
Baby boy arrived 11/13/14!
Began TTC #1 in Sept. 2010. I was 33, DH was 36.. Dx with DOR and slight MFI (8/4/11).
Test results (after first RE visit 6/21/11): 7DPO b/w: Progesterone = 11.3; CD3 b/w: FSH = 10.1 mUnits/mL, E2= 52.0 pg/mL, AFC: 6; SIS Ultrasound: Uterus great, tubes clear! AMH: 0.3
IUI#1 June 2012 (Follistim/HCG trigger): BFN
IUI#2 July 2012 (Follistim/HCG trigger): BFN
IUI#3 August 2012 (Follistim/HCG trigger): CP (Beta #1: 4.61, Beta #2: 1.0)
IUI#4 October 2012 (Follistim, ovulated before trigger, missed IUI, converted to TI): BFN
Jan. 2013 New RE
IVF #1 June 2013 MDL Protocol. Converted to IUI#4.1. (High E2 and 3+ mature follicles at first monitoring.) BFFN
IVF #1.2 August 2013 Stop Lupron Protocol with Human Growth Hormone added. 17R, 14M, 9F (with ICSI), 2 embryos (decent quality - grade 2) transferred on day 3, 2 blasts made it to freeze. Beta 8/26. BFFN
FET #1 December 2013 Last try! Transferred 2 blasts -- graded 3AB and 4BB. Beta #1 (12/27/13) 530. Beta #2 (12/30/13) 1876. BFP! One bean. EDD 9/3/2014!
We welcomed the most beautiful baby girl into the world on September 11, 2014!
12/2011: Finished chemo
5/2013: Cleared for DE IVF
11/13: DEgg IVF#1
8/5/14: Grace was born!
6 rounds of clomid = no luck
IVF w/ ICSI & AZH #1 - Jan/2011 = ET cancelled OHSS
FET #1 & #2 - March/2011 & June/2011 = Chemical Preg.
IVF w/ Half ICSI #2 New RE - May/2012 = BFN!
May '12 - Sep '13 - Took A Break
Dec '13 IVF w/ Half ICSI #3!!!!! Switched RE
Protocol - Lupron trigger/Follistim/Ganirelix/Estrace/Vivelle/Crinone
6/27/14 - Emergency C/S @ 30w2d - Baby A 2lb 14oz, Baby B 2lb 11 oz