Trying to decide how to best approach my doctor about this and what to ask questions about...Metformin, HCG shots, Progesterone suppositories, Clomid...first pregnancy in Jan 2011 was a chem. pregnancy loss, my DD is a Clomid baby, but since I've had another chemical pregnancy loss since DD's birth, I am wondering if maybe I should incorporate one or more of these others in with the Clomid this time. Anyone had any experience/success with a combination of the above mentioned therapies?
ME: 24 with PCOS and a HX of Endo (rem. 04/12) DH: 24 with Low Motility TTC since 11/09 M/C 01/11 at >2w, chemical pregnancy 50mg Clomid 02/12, -OPK 100mg Clomid 03/12, -OPK Surgery to remove endo. and check tubes 04/04/12 10d Provera & 150mg Clomid 05/12, 1st positive OPK! BFP 06/12 DD born 01/30/13!!! TTC #2 since 09/13 Last Normal Cycle 12/16/13 Neg OPKs in 01/14 Neg Prog. in 01/14 10d Provera started 01/21/14 SURPRISE BFP 02/06/14 ER Visit 02/15/14, u/s showed empty uterus, BHCG = 111 M/C 02/16/14, chemical pregnancy...M/C was confirmed 2/18/14, BHCG = 28 05/12/2014 Started 50 mg Clomid 05/16/2014 Ended 50 mg Clomid 05/28/2014 Negative "Day 21"
progesterone bloodwork 06/06/2014 BFP!!! 06/09/2014, beta HCG 75 06/12/2014 beta HCG 242! 06/20/2014 beta HCG 2823! 06/26/2014 m/c at 6w1d 07/21/2014 diagnosed with APS (Lupus Anticoagulant), Factor V,
and MTHFR mutation in addition to PCOS and HX of
Endometriosis 10/27/2014 repeat Lupus Anticoagulant tested negative
Clomid never worked for me, but Clomid plus trigger could help a lot if your issue is releasing eggs that aren't quite mature- that could (potentially) explain the CPs. Just make sure they are monitoring you closely with this combo- you don't want to be the next octomom!
Progesterone never hurts anything. Idk about the metformin.
Good luck!
Spontaneous pregnancy #1 DD1 July 31, 2011
Trying for #2 since Oct 11
732973 Clomid Cycles
2 IUIs
3 Fresh IVFs= 1 Ectopic treated with MTX Spontaneous pregnancy #2= Ectopic #2= lost left tube Spontaneous pregnancy #3= DD2 January 29, 2016 Spontaneous pregnancy #4= Ectopic #3 Spontaneous pregnancy #5= Baby #3 is a BOY!!!
I agree with PP. And please correct me if I'm wrong about this, but I seem to remember being told that its a common thing for PCOSers to have progesterone deficiency/ luteal phase defect issues.
I think you should be on metformin now. If you have PCOS, taking metformin will address the root cause and help get your body ready and balanced BEFORE you become pregnant. You want your body at its best before you become pg so that it's ready to receive the fertilized egg.
As far as clomid and/or trigger, it sounds like you had success before and I would try it again if I were in your place. Clomid made my lining too thin, so it's not an option for me. But I wish it were! I would probably be doing it now if I thought it would help me!
I would also push for progesterone if I were in your shoes. I took it for the first 10 weeks with my son even though I didn't use other medical interventions to conceive him. I think it's better safe than sorry.
Happily Mrs. C
start ttc #1 in Jan 2009
dx PCOS in May 2010, begin metformin
Two failed clomid cycles (made lining too thin)
Started acupuncture while saving for IVF in Sept 2011
Add herbal infusions to the mix in Dec 2011
Hoping holistic approach works!!!
BFP on April 2012 at 11dpo
Meepy Man born on Jan 2013 - Hip Hip Hurray!
Ready to start ttc #2 April 2013, but plan to be an extended BF'er
Back on metformin Aug 2013
Restart herbal infusions Sept 2013 - currently drinking nettle, oatstraw, and red raspberry leaf
DS weaned in April 2014
Taking a break from herbs and just riding the healthy train.
Planning medicated cycle end of summer. FX I get KU before then!!!
Re: Recurrent M/C and PCOS
Spontaneous pregnancy #1
DD1 July 31, 2011
Trying for #2 since Oct 11
Spontaneous pregnancy #2= Ectopic #2= lost left tube
Spontaneous pregnancy #3= DD2 January 29, 2016
Spontaneous pregnancy #4= Ectopic #3
Spontaneous pregnancy #5= Baby #3 is a BOY!!!