Hi ladies! I am a lurker here but post over on IF vets and IF....I am currently waiting to cycle again in April and my doctor mentioned possibly doing endometrial scratching this cycle. Any insight would be wonderful. When in your cycle did your RE perform this? Was it painful? Will I have to take off work? Any negative side effects? Success? I am just worried that this will cause bleeding and my last transfer was cancelled because I had a blood filled cyst and blood in my uterus. Of course I will go over this with my RE when the time gets closer but this "off period" has be bored to death and wanting to do something IF related to make me feel like I am moving towards my goal! Thanks ladies! So happy to see so many familiar "faces" that are doing so well! I hope to join you ladies someday soon!
TTC 2 years- Me and DH (28) with (severely) low sperm count- less than 40 total (last 2 SA showed only 5 and 6 sperm each) IVF #1: ER 1/23/13- 4 eggs retrieved,
3 eggs fertilized; ET with 1 embryo 1/28/13
2 frosties
beta #1 2/5 was 4.8- beta #2 2/7 3.5; BFN
FET #1- transferred one beautiful 4AA embie. Praying this is my take home baby. Beta 5/7/13- BFFN!!!
IVF #2: ER 7/17/13: 6R/3F- transferred 1 blast and 1 10 cell embryo 5dt. Beta hell. #1 2.5, #2 2.2- BFFFN! REALLY? IVF #3: ER 12/1 and only 2 retrieved. 1 fertilized with ICSI. Was planning on transferring one fresh and one frozen....fresh was only 14 cells at day 5...CANCELLED and devastated due to 5cm blood filled cyst in ovary and blood in uterus. IVF #4: Antagonist protocol with endometrial scratch day one of stims. ER 4/21: 6R/4M/3F- transferred 2 beautiful blasts (5dt) and one was hatching! No frosties but hoping we won't need it! Beta 5/4/14- 444(8dp5dt), Beta #2 10dp5dt 1002! THIS HAS GOT TO BE IT!!!!!!!!!! First US 5/15 we saw two of the most beautiful gestational and yolk sacs I have ever seen! ****FINALLY PREGNANT WITH DI/DI TWINS!!!!!!!
BRINLEY AND RILEY LONG. Born November 20, 2014 at 32 wks 3 days. 4lbs7oz and 4lbs5oz. 1 month NICU time for "B's" and growing and feeding. Now healthy, thriving, beautiful little girls! pg
We did NOT do the scratching, but my RE said that if they have someone that went through 2 unsuccessful IVF cycles, they recommend it because it does increase success rates. He said we could have done it if we wanted, but that some people say it is one of the more painful procedures that they have done, so we opted not to. However, I want to say someone on the IF board did it and said it wasn't so bad. I'm not sure what their outcome was, though.
I had the scratch done after 3 unexplained failed ivf cycles. I was basically considered a case of "unexplained implantation failure", so the scratch seemed to be a last hope. Well, I am now just over 19 weeks pregnant with twins. Obviously, there is no way to ever know if the success was due to the scratch, but it certainly didn't hurt the situation, so I think it was totally worth it!! I did it in the cycle before my FET, so I am not exactly sure the timing of when it is done for a fresh cycle. I am pretty sure that it is also supposed to be done the cycle before retrieval and not in the same cycle. As for pain, it's not the most fun thing, but it's also not the worst. It is a very short (15 sec) procedure. They scratch 4 quadrants of the lining, so my doc would say 12:00, 3:00, 6:00, and 9:00, as he went around and scratched the 4 areas. I closed my eyes, held my breathe, and it was over. Expect to be a bit crampy and just take it easy and be a couch potato for the rest of the day. I never had any bleeding, maybe just a teeny bit of spotting, but everyone is different. I was perfectly fine the next day. Also, I would suggest taking Advil or something about an hour before the procedure. None of these procedures are enjoyable, but I would do it again a million times over if it helped get me to where I am today! Wishing you the best of luck and hope to see you over here soon!! Oh, and if you have any more questions, feel free to pm me!
Just curious- are they planning on doing the biopsy to check for the beta 3 integrin or just the scratch?
*****Siggy/Ticker Warning*****
Me (34)- no issues found MH (36)- MFI due to Vericocele. Straight to IVF w/ICSI 9/12, Antagonist. 9R, 7M, 5F = BFN c/p, New RE for IVF #2- 1/13., Long Lupron. ER on 1/22 -10R, 9M, 9F. Transfer on hold due to overstimming. FET in Feb. 2 frozen blasts. Another BFN & another c/p. RPL testing all negative besides MTHFR gene, vericocle repair surgery 4/12/13-Bilateral Grade 3 Vericocele found & fixed, IVF #3 with PGS 4/13- 11R, 9M, 9F. Transferred 2 normal=BFN, 3 normal on ice. CCRM-here we come! ODWU-All test results normal. EPP in August. 21R, 20M, 19F. 12 blasts biopsied & frozen for CCS testing. Results showed 11 normal! FET Oct. 30. 2 5d 4AA blasts transferred. First ever BFP!!! Beta 1=216, Beta 2=870 1st U/S=It's TWINS!!! It's a BOY and aGIRL!!Everyone Welcome!!!
I've done the scratch. It didn't work magic for me, but I wouldn't hesitate to do it again, because I think there are very few negatives to it. My experience was very similar to @JSM0801. It was pretty painful- but only for literally seconds. 4 scratches, then done. I took Tylenol before. I spotted & cramped minimally immediately after and was completely fine the next day. I don't remember where in my cycle it was, but maybe my sight says it? (I'm mobile bumping so I can't see it) Look at IVF 4. Good luck!
PAIF/SAIF Welcome!
Me: 42, Hubby: 35, TTC since Jan 2010. Dx: DOR due to advanced maternal age.
Also: Hypothyroidism (100mcg Levothyroxin). Positive for MTHFR (hetero-C677T), Factor V Leiden, and Fragile X (on DH side). Taking pre-natal vitamins. First natural PG 9/27/11; mc: 1/20/12 First RE visit: 8/8/12, Saline Sonogram: 8/28/12, IVF injection class: 10/11/12, add FaBB Tab for FVL, +Vitamin D. IVF #1:
10/17/12 Baseline: FSH- 9.4, E2- 24, LH- 3.7, Prog- 0.3 The u/s
showed 6 follicles in my right & 9 in my left. Rx: 150 Bravelle &
150 Menopur SQ nightly. 10/21/12: Add Ganirelix SQ every morning.
ER 10/28/12: 13 Retreived. 7 Mature. 6 Fertilized. 5 Made it to PGS. ET
11/2/12: CANCELED. All 5 came back from PGS as having "severe
abnormalities." IVF #2:
1/7/13 Baseline: FSH- 8.8, 4 follicles in my right & 6 in my left.
Rx: 150 Bravelle & 150 Menopur SQ nightly. 1/11/13: Add Ganirelix SQ every
morning. hCG Trigger 1/16/13
ER 1/18/13: 9 Retrieved. 5 Mature. 5 Fertilized. 2 Made it to PGS. ET 1/23/13:
CANCELED. All embryos (he even sent the ones not growing) came back from PGS as
having "multiple severe abnormalities." IVF #3: NEW RE! 3/1/13 Baseline: FSH- 9.6, E2- 61, Prog- 0.94, 3
follicles in my right & 4 in my left. Rx: 150 Bravelle& 150
Menopur SQ in PM. 3/7/13: Add Ganirelix SQ in AM. hCG Trigger 3/9/13 SQ. ER 3/11/13: 6R, 2M, 2F. Day 3: one 8 cell, grade 0. Five day ET 3/16/13: one
early blast, grade Fair. 3/24/13 AF came a day before beta. BFN IVF #4:(Added acupuncture to this cycle.) 3/25/13 WTF & Baseline:
FSH-11.8, E2- 56, Prog- 0.84 3/26/13 Start stims. 3/30/13 u/s: 5
follicles in my right & 4 in my left. Rx: 225 Bravelle& 225
Menopur SQ in PM. 3/31/13 Add Ganirelix SQ in AM.hCG Trigger 4/3/13 SQ. ER 4/5/13: 5R, 3M, 3F naturally. Day 3: two 8 cell, grade 0, one 8 cell, grade 2
(Scale 0-best to 3-worst). Five day ET 4/10/13: two blastocysts (the 3rd
stopped growing.) Beta 4/18/13: 2.5 BFFN. RE recommends we stop trying and
focus on living childless, due to the extremely poor quality of my
eggs. ***Decided
to stop trying and live CFNBC. I couldn't adjust. So, six months later... IVF #5: Changed RE. Going to one of the big name clinics now.
OWDU: 10/29/13. Update: HORRIBLE experience. Disgusted and distraught at their complete unprofessionalism and how much money and precious time they cost us. Sickening. Have now changed RE again. New Patient appt. 1/30/14. BFP! Out of nowhere, I got KU the old fashioned way! POAS 1/26/14 - Positive! FDLM 12/30/13. Beta #1 16dpo= 373. Beta #2 18dpo= 801. EDD 10/6/14 2/4/14 1st U/S revealed a 5wk2day sac but no fetal pole. Started 200mgs of progesterone suppositories daily 2/11/14 2nd U/S revealed a perfect 6wk1day "diamond ring" embryo with a beating heart! 138bpm! Add 1mg folic acid and 40mg Lovenox 2/25/14 3rd U/S: perfect 8w1d embryo, 178bpm. 3/6 start spotting. 3/11 10w1d U/S shows no heartbeat. Scheduling D&C. The Stork has forsaken me again. IVF #5.2: New in-state RE. Supplement priming for 1.5 cycles prior to start of cycle, including DHEA 50mg (stopped 5/15), CoQ10 200mg 2x/day, L-Arginine- 1000mg 2x/day (stopped 6/5 due to cold sore!), myo-inositol- 2g 2x/day, melatonin- 3mg, and Neevo (prenatal for MTHFR). 5/16/14 Day 2 bw cycle prior: FSH- 12.22, E2- 38.37, Prog- 1.35, LH- 9.46. 6/2/14 Day 19 bw: Prog- 23 6/12/14 Baseline: E2- 122.7, Prog- 0.4. 5 follicles in left, 4 follicles in right. Start stims: 375IU Follistim & 150IU Menopur. 6/19 Increase Follistim to 425IU, Menopur still 150IU. 6/18 add Ganirelix. 6/23 Ovidrel trigger SQ. 6/25 ER: 8R, 8M, 5F naturally. Start Medrol & Doxy. 6/26 Start Endometrin. 7/2 Start Lovenox. 7/8/14 Beta= 137.4 BFP!!! (My first from IVF!) E2- 1109, Prog- >60. Stop CoQ10, myo-inositol, and melatonin. 7/9 2nd Beta= 281.4. TSH- 2.70. Increasing Synthroid to 100mcg daily. 7/24 6w3d u/s measured 6w3d, hb: 121bmp! 8/5 8w1d u/s measured 8w3d, hb: 164bpm! Graduated from RE to OB. Now I just need to find an OB! EDD 3/18/15!
Thank you for posting this!! I'm doing IVF starting March 2014 and it's with an IVF Study through RMA NJ, part of the study is that we have the Endometrial Scrape and I was told it will increase our chances of implantation! GOOD LUCK to you keep me posted!
******Siggy Warning Loss Mentioned******
Me = 34 Unexplained IF/ Ovulation Issues
DH = 34 Perfect
TTC 4 Years
Married 7, together 15 years.
1 miscarriage at 18 years old
3 Failed IUI's with injectables NEXGEN IVF Study at RMA March 2014 Resulted in 8 embryos FET #1: April 2014, loss at 11 weeks FET #2: July 2015. Walker born 2/26/16!
Currently waiting for AF, Starting FET #3 January 2017! 4 more frozen embryos!
Re: endometrial scratching??
Me (34)- no issues found MH (36)- MFI due to Vericocele. Straight to IVF w/ICSI 9/12, Antagonist. 9R, 7M, 5F = BFN c/p, New RE for IVF #2- 1/13., Long Lupron. ER on 1/22 -10R, 9M, 9F. Transfer on hold due to overstimming. FET in Feb. 2 frozen blasts. Another BFN & another c/p. RPL testing all negative besides MTHFR gene, vericocle repair surgery 4/12/13-Bilateral Grade 3 Vericocele found & fixed, IVF #3 with PGS 4/13- 11R, 9M, 9F. Transferred 2 normal=BFN, 3 normal on ice. CCRM-here we come! ODWU-All test results normal. EPP in August. 21R, 20M, 19F. 12 blasts biopsied & frozen for CCS testing. Results showed 11 normal! FET Oct. 30. 2 5d 4AA blasts transferred. First ever BFP!!! Beta 1=216, Beta 2=870 1st U/S=It's TWINS!!! It's a BOY and a GIRL!! Everyone Welcome!!!
My BLOG: www.ivfbabyquest.wordpress.com -Update - old blog.
PAIF/SAIF Welcome!
Me: 42, Hubby: 35, TTC since Jan 2010. Dx: DOR due to advanced maternal age. Also: Hypothyroidism (100mcg Levothyroxin). Positive for MTHFR (hetero-C677T), Factor V Leiden, and Fragile X (on DH side). Taking pre-natal vitamins.
First natural PG 9/27/11; mc: 1/20/12
First RE visit: 8/8/12, Saline Sonogram: 8/28/12, IVF injection class: 10/11/12, add FaBB Tab for FVL, +Vitamin D.
IVF #1: 10/17/12 Baseline: FSH- 9.4, E2- 24, LH- 3.7, Prog- 0.3 The u/s showed 6 follicles in my right & 9 in my left. Rx: 150 Bravelle & 150 Menopur SQ nightly. 10/21/12: Add Ganirelix SQ every morning.
ER 10/28/12: 13 Retreived. 7 Mature. 6 Fertilized. 5 Made it to PGS. ET 11/2/12: CANCELED. All 5 came back from PGS as having "severe abnormalities."
IVF #2: 1/7/13 Baseline: FSH- 8.8, 4 follicles in my right & 6 in my left. Rx: 150 Bravelle & 150 Menopur SQ nightly. 1/11/13: Add Ganirelix SQ every morning. hCG Trigger 1/16/13
ER 1/18/13: 9 Retrieved. 5 Mature. 5 Fertilized. 2 Made it to PGS. ET 1/23/13: CANCELED. All embryos (he even sent the ones not growing) came back from PGS as having "multiple severe abnormalities."
IVF #3: NEW RE! 3/1/13 Baseline: FSH- 9.6, E2- 61, Prog- 0.94, 3 follicles in my right & 4 in my left. Rx: 150 Bravelle& 150 Menopur SQ in PM. 3/7/13: Add Ganirelix SQ in AM. hCG Trigger 3/9/13 SQ.
ER 3/11/13: 6R, 2M, 2F. Day 3: one 8 cell, grade 0. Five day ET 3/16/13: one early blast, grade Fair. 3/24/13 AF came a day before beta. BFN
IVF #4: (Added acupuncture to this cycle.) 3/25/13 WTF & Baseline: FSH-11.8, E2- 56, Prog- 0.84 3/26/13 Start stims. 3/30/13 u/s: 5 follicles in my right & 4 in my left. Rx: 225 Bravelle& 225 Menopur SQ in PM. 3/31/13 Add Ganirelix SQ in AM.hCG Trigger 4/3/13 SQ.
ER 4/5/13: 5R, 3M, 3F naturally. Day 3: two 8 cell, grade 0, one 8 cell, grade 2 (Scale 0-best to 3-worst). Five day ET 4/10/13: two blastocysts (the 3rd stopped growing.) Beta 4/18/13: 2.5 BFFN. RE recommends we stop trying and focus on living childless, due to the extremely poor quality of my eggs.
***Decided to stop trying and live CFNBC. I couldn't adjust. So, six months later...
IVF #5: Changed RE. Going to one of the big name clinics now. OWDU: 10/29/13. Update: HORRIBLE experience. Disgusted and distraught at their complete unprofessionalism and how much money and precious time they cost us. Sickening. Have now changed RE again. New Patient appt. 1/30/14.
BFP! Out of nowhere, I got KU the old fashioned way! POAS 1/26/14 - Positive! FDLM 12/30/13. Beta #1 16dpo= 373. Beta #2 18dpo= 801. EDD 10/6/14
2/4/14 1st U/S revealed a 5wk2day sac but no fetal pole. Started 200mgs of progesterone suppositories daily
2/11/14 2nd U/S revealed a perfect 6wk1day "diamond ring" embryo with a beating heart! 138bpm! Add 1mg folic acid and 40mg Lovenox
2/25/14 3rd U/S: perfect 8w1d embryo, 178bpm. 3/6 start spotting. 3/11 10w1d U/S shows no heartbeat. Scheduling D&C. The Stork has forsaken me again.
IVF #5.2: New in-state RE. Supplement priming for 1.5 cycles prior to start of cycle, including DHEA 50mg (stopped 5/15), CoQ10 200mg 2x/day, L-Arginine- 1000mg 2x/day (stopped 6/5 due to cold sore!), myo-inositol- 2g 2x/day, melatonin- 3mg, and Neevo (prenatal for MTHFR).
5/16/14 Day 2 bw cycle prior: FSH- 12.22, E2- 38.37, Prog- 1.35, LH- 9.46. 6/2/14 Day 19 bw: Prog- 23
6/12/14 Baseline: E2- 122.7, Prog- 0.4. 5 follicles in left, 4 follicles in right. Start stims: 375IU Follistim & 150IU Menopur. 6/19 Increase Follistim to 425IU, Menopur still 150IU. 6/18 add Ganirelix. 6/23 Ovidrel trigger SQ. 6/25 ER: 8R, 8M, 5F naturally. Start Medrol & Doxy. 6/26 Start Endometrin. 7/2 Start Lovenox.
7/8/14 Beta= 137.4 BFP!!! (My first from IVF!) E2- 1109, Prog- >60. Stop CoQ10, myo-inositol, and melatonin. 7/9 2nd Beta= 281.4. TSH- 2.70. Increasing Synthroid to 100mcg daily. 7/24 6w3d u/s measured 6w3d, hb: 121bmp! 8/5 8w1d u/s measured 8w3d, hb: 164bpm! Graduated from RE to OB. Now I just need to find an OB!
EDD 3/18/15!
Edit: double post, sorry
Age: 35 TTC since 2005, MFI & DOR
IVF #1 Sep '11 - canceled poor response
IVF #2 Nov '11 8R/8M/4F 3dt x2 - chemical
IVF #3 April '12 11R/6M/4F 3dt x2 - m/c
FET #1 Aug 2012 3dt x2 - BFN
**new RE**
IVF #4 Jan '13 BFN 11R/6M/6F 5dt x2 - BFN
IVF #5 July '13 16R/10M/10F 5dt x2 + 1 frostie
9dp5dt Beta 1 = 344!! 16dp5dt. Beta 2 = 4822 7wk u/s= 2 heartbeats!
Twin girls! 3/6/14
Well, I don't know what happened to my double post so here are my answers again:
When in your cycle did your RE perform this? It was around CD 14 the cycle before we stimmed.
Was it painful? Not any worse than a pap smear for me. It was much less painful for me than the saline sono and the HSG.
Will I have to take off work? I did it on a Friday afternoon after leaving work so I went home, but in hindsight I could have gone back to work.
Any negative side effects? Just some spotting the same day. I took Tylenol as a precaution.
Success? Yes. Not sure if it's attributable to the scratch, but certainly no regrets here.
Age: 35 TTC since 2005, MFI & DOR
IVF #1 Sep '11 - canceled poor response
IVF #2 Nov '11 8R/8M/4F 3dt x2 - chemical
IVF #3 April '12 11R/6M/4F 3dt x2 - m/c
FET #1 Aug 2012 3dt x2 - BFN
**new RE**
IVF #4 Jan '13 BFN 11R/6M/6F 5dt x2 - BFN
IVF #5 July '13 16R/10M/10F 5dt x2 + 1 frostie
9dp5dt Beta 1 = 344!! 16dp5dt. Beta 2 = 4822 7wk u/s= 2 heartbeats!
Twin girls! 3/6/14
NEXGEN IVF Study at RMA March 2014
Resulted in 8 embryos
FET #1: April 2014, loss at 11 weeks
FET #2: July 2015. Walker born 2/26/16!
4 more frozen embryos!