Infertility

HGH

Anyone use HGH (Human Growth Hormone) and get a good result?  That is one of the things my new RE mentioned along with other stuff.  He said I can try HGH to improve embryo quality but theres no guarantee. He said its about $400-$500 and you take it while sitmming. He said it can't hurt.  

So anyone use it? If so please share.
***SIGGY WARNING***

DX: Unexplained
6 Failed IUIs (Clomid and Gonal F).  
IVF #1 began August 2013- BC, 4 days of Estrace, stimmed with Gonal F and Menopur, Ganirelix, 9R 5M 5F, Medrol and Doxycycline, 5 day transfer of 2 early blastocysts- good quality, Progesterone, Estrace, and baby aspirin, BETA on 9/20 BFN,   IVF #2 began September 2013, stimming with Gonal F (higher dose) and Menopur, Ganirelix, 18R 14M 9F with ICSI, 5 day transfer of 2 BBs one was starting to hatch, 2 frosties: 1  BB and 1 AC, BETA on 10/21, BFN BETA was a 5- chemical 
Getting some more testing and trying to figure out what the issue is before FET in December, started acupuncture on 11/10, RLP and some other BW nothing major to report except slightly high Prolactin. Prolactin was slightly high when I started with my RE and I already had an MRI which was Neg.  Endo biopsy=negative.  WTF is wrong with us???
12/18/13 FET of 1 BB and 1 AC.  Hoping for a miracle.  Beta 12/26 Low BETA-8 2nd BETA 5- chemical
After 3 failed transfers IDK where to go from here.  Still no real answers as to why this isn't working.  Getting a second opinion in February and looking into immune testing.  
2/14- NEW RE- Immune testing showed a partial dq alpha match with DH- On prednisone and did intralipids prior to transfer.  3/14 Lupron, gonal f, menopur, HGH.  ER 15 mature all 15 fertilized!  5dt of an early blast grade 1 and an expanded blast grade 2.  BETA on 4/21.  1 grade 2 embryo frozen
BETA #1 59 BETA #2 148 BETA #3 283 BETA #4 2,783! US at 6w2d shows 1 bean measuring right on track! HR 121.  US at 8w3d measuring on track HR 177. Released form my RE.  EDD 12/28


All Welcome

Re: HGH

  • This question has been asked a few times recently, so you might try doing a search to see what people said. :) Not everyone would likely respond again.

    Good luck!
    **********************siggy/ticker warning**********************

    ***Losses mentioned.*** TTC #1 since May 2012. Me: 37, OH: 41. Ectopic August 2012 => tubal damage. :'(  Stage 1 endo removed June 2013. IVF #1 Oct/Nov 2013: Long Lupron with Gonal-F. 7R, 7M, 7F. 2 txfer@3d. Nothing frozen.  => M/C @ 8 wks. :'( Selected RPL panel all normal. Very hyper and brittle response to stims. IVF #2 (antagonist protocol) Feb 2014 => Converted to IUI (Perfect conditions). BFN. IVF #2.1 w/ new RE June 2014: Antagonist protocol. 33R, 31M, 30F, 19 blasts to test!!! I made it through without crashing!! :) Hats off to Dr. Fancypants!! ET of one 5AB blast. BFN. 13 10 CCS'ed snowflakes! FET #1 PUPO as of 7/29 Betas: 8/7@24, 8/9@97, 8/11@334 (etc.) Two sacs on 8/15, one seen on 8/18 after a bleed. U/s 8/25 (6+3) "perfect": 5.9 mm + HB@120bpm! U/s 9/4 (7+6): 15.9 mm + HB@172 bpm! Please, PLEASE stick this time!!!!
    http://i955.photobucket.com/albums/ae39/catfreeburg/866da40f5178fed79efe23fc8a4e8a_zps4498a9cc.jpgimageimageimageimage
    image
  • Loading the player...
  • I did it on IVF #2 (canceled after ER due to all embryos arresting). It was easy to take, but in my case did not help.
    **SIGGY WARNING**

    Me: 32 DH: 35  TTC#1 since March 2012
    Dx: Poor Embryo Quality, Arcuate Uterus, Poor Uterine Blood Flow, Mild Endo, 
           Protein S Deficiency, Sjorgen's Syndrome 

    IUI #1-5: BFN
    Laparoscopy & Hysteroscopy: minimal endo, partial septoplasty
    IVF #1: 10R/6M/6F ~ Day 3 ET = BFN
    IVF #2: 14R/9M/5F ~ transfer canceled ~ all embryos arrested at 1-2 cell stage
    IVF #3: 9R/5M/5F ~ 1 frosty!
    IVF #4 (FET #1): BFN

    IVF #5 (DE IVF #1 with Dr. KK protocol): Currently PREGNANT!!!!!!
    Synthroid + Prednisone + Metformin + Baby Aspirin + Supplements Galore = 15+ pills a day
    Lupron + Lovenox + Delestrogen + IVIG + B/W = 2-5 pokes a day
    19R, 17M, 17F - transferred two Grade A blasts 11/16, four frosties!!!
    Beta #1 11/24 (13dpo/8dp5dt) = 367 ~ Beta #2 11/26 (15dpo/10dp5dt) = 709
    Beta #3 11/29 (18dpo/13dp5dt) = 1,997 ~ Beta #4 12/1 (20dpo/15dp5dt) = 3,403

    imageimageimage

    My Blog: Running and Dreaming for Two ~ All are Welcome!
  • pblge said:
    This question has been asked a few times recently, so you might try doing a search to see what people said. :) Not everyone would likely respond again. Good luck!
    OH I must have missed it.  Thanks
    ***SIGGY WARNING***

    DX: Unexplained
    6 Failed IUIs (Clomid and Gonal F).  
    IVF #1 began August 2013- BC, 4 days of Estrace, stimmed with Gonal F and Menopur, Ganirelix, 9R 5M 5F, Medrol and Doxycycline, 5 day transfer of 2 early blastocysts- good quality, Progesterone, Estrace, and baby aspirin, BETA on 9/20 BFN,   IVF #2 began September 2013, stimming with Gonal F (higher dose) and Menopur, Ganirelix, 18R 14M 9F with ICSI, 5 day transfer of 2 BBs one was starting to hatch, 2 frosties: 1  BB and 1 AC, BETA on 10/21, BFN BETA was a 5- chemical 
    Getting some more testing and trying to figure out what the issue is before FET in December, started acupuncture on 11/10, RLP and some other BW nothing major to report except slightly high Prolactin. Prolactin was slightly high when I started with my RE and I already had an MRI which was Neg.  Endo biopsy=negative.  WTF is wrong with us???
    12/18/13 FET of 1 BB and 1 AC.  Hoping for a miracle.  Beta 12/26 Low BETA-8 2nd BETA 5- chemical
    After 3 failed transfers IDK where to go from here.  Still no real answers as to why this isn't working.  Getting a second opinion in February and looking into immune testing.  
    2/14- NEW RE- Immune testing showed a partial dq alpha match with DH- On prednisone and did intralipids prior to transfer.  3/14 Lupron, gonal f, menopur, HGH.  ER 15 mature all 15 fertilized!  5dt of an early blast grade 1 and an expanded blast grade 2.  BETA on 4/21.  1 grade 2 embryo frozen
    BETA #1 59 BETA #2 148 BETA #3 283 BETA #4 2,783! US at 6w2d shows 1 bean measuring right on track! HR 121.  US at 8w3d measuring on track HR 177. Released form my RE.  EDD 12/28


    All Welcome
  • RunCC37 said:
    I did it on IVF #2 (canceled after ER due to all embryos arresting). It was easy to take, but in my case did not help.
    Sorry it didn't help but thanks for sharing.
    ***SIGGY WARNING***

    DX: Unexplained
    6 Failed IUIs (Clomid and Gonal F).  
    IVF #1 began August 2013- BC, 4 days of Estrace, stimmed with Gonal F and Menopur, Ganirelix, 9R 5M 5F, Medrol and Doxycycline, 5 day transfer of 2 early blastocysts- good quality, Progesterone, Estrace, and baby aspirin, BETA on 9/20 BFN,   IVF #2 began September 2013, stimming with Gonal F (higher dose) and Menopur, Ganirelix, 18R 14M 9F with ICSI, 5 day transfer of 2 BBs one was starting to hatch, 2 frosties: 1  BB and 1 AC, BETA on 10/21, BFN BETA was a 5- chemical 
    Getting some more testing and trying to figure out what the issue is before FET in December, started acupuncture on 11/10, RLP and some other BW nothing major to report except slightly high Prolactin. Prolactin was slightly high when I started with my RE and I already had an MRI which was Neg.  Endo biopsy=negative.  WTF is wrong with us???
    12/18/13 FET of 1 BB and 1 AC.  Hoping for a miracle.  Beta 12/26 Low BETA-8 2nd BETA 5- chemical
    After 3 failed transfers IDK where to go from here.  Still no real answers as to why this isn't working.  Getting a second opinion in February and looking into immune testing.  
    2/14- NEW RE- Immune testing showed a partial dq alpha match with DH- On prednisone and did intralipids prior to transfer.  3/14 Lupron, gonal f, menopur, HGH.  ER 15 mature all 15 fertilized!  5dt of an early blast grade 1 and an expanded blast grade 2.  BETA on 4/21.  1 grade 2 embryo frozen
    BETA #1 59 BETA #2 148 BETA #3 283 BETA #4 2,783! US at 6w2d shows 1 bean measuring right on track! HR 121.  US at 8w3d measuring on track HR 177. Released form my RE.  EDD 12/28


    All Welcome
  • I have answered this a few times recently, but no reason I can't tell you my experience, too. ;) We had success on IVF attempt #5 with several changes to our protocol. One of the changes included HGH. It did cost more than your doctor quoted you. Ours was closer to $8-900, but perhaps you have insurance or will be on a different dose than I was. I believe we did 3 injections total toward the end of our stim cycle. Good luck and feel free to ask this on SAIF or PAIF for more success stories. I would definitely add HGH if I had it to do over again but since was also made other changes to our protocol I cannot solely attribute our success to it. 

    Age: 35 TTC since 2005, MFI & DOR 

    IVF #1 Sep '11 - canceled poor response

     IVF #2 Nov '11  8R/8M/4F 3dt x2 - chemical

    IVF #3 April '12  11R/6M/4F 3dt x2 - m/c

    FET #1 Aug 2012  3dt x2 - BFN

    **new RE**

     IVF #4 Jan '13 BFN 11R/6M/6F 5dt x2 - BFN

     IVF #5 July '13 16R/10M/10F 5dt x2 + 1 frostie

    9dp5dt Beta 1 = 344!! 16dp5dt. Beta 2 = 4822 7wk u/s= 2 heartbeats!

    Twin girls! 3/6/14

     

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