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Triggering too early?

Hi there, I'm on my 4th iui and went in for my ultrasound today. This cycle I was on 5mg of Femara days 3-7. Today I had 3 follies- 16.5, 16, and 15. My RE seemed really happy with the size and told me to trigger late tonight for an iui Sunday. I was looking stuff up on follicle size on google (blargh) and now I'm completely freaked that I'm triggering too early. What do your re's trigger at? I'm really worried now that I'm wasting an iui cycle for nothing. Tia ladies!
Me: 28 Husband:: 29
TTC  since April, 2012; Diagnosed with Hashimotos, Annovulatory.
October, 2013- Metformin + 50mg Clomid + iui - BFN
November, 2013- Metformin + 50mg Clomid + iui + Prometrium 2x a day- Chemical Pregnancy



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Re: Triggering too early?

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    I went yesterday and had a 15.5 follie. My RE told me I seemed to be growing at about 1.5mm/day. So today would be about 17.5. I triggered tonight. When I actually ovulate, I should be around 19, if the math is wrong or I slow down, I will still be an 18.

    This is my first trigger, so I'm not sure if this is typical protocol, but I went ahead without questioning it too much, I figure they know better than I.
    10/2013 - Initial consult. Started levothyroxine - tsh 2.92
    HSG- showed graying in one spot/Saline Sono- showed 5mm polyp
    DH SA -  abnormal -  36%motility on both SA's (count and morph ok on SA1, a little off SA2)
    1/10/14 - Hysteroscopy to remove 5mm polyp
    1/12/14- Medicated Cycle 1: 50mg Clomid + Ovidrel + TI = BFN
    2/15/14 - Medicated Cycle 2: 100mg Clomid + Ovidrel + TI = BFN
    3/18/14 - IUI Cycle 1: 150mg Clomid + Ovidrel + IUI = BFN
    Upped Levothyroxine to 50mg - tested at 2.62
    4/17/14 - IUI Cycle 2: 150mg Clomid + Ovidrel + IUI = BFN
    Break!
    6/21/14: IUI Cycle 3: 150mg Clomid + Ovidrel + IUI

    *All are welcome*




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    I don't know what's normal this was my first medicated cycle but I had 1 at 18 Monday morning. He told me one more shot of my Gonal that night and trigger the next morning.

    Fucking bump!!!!
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    Well they grow from 1-2 mm a day so you could potentially have another 1.5 to 3 mm of growth by the time you actually ovulate so that could be perfect.

    Me: 32  DH: 33  Married: March 2004

    July 2006: started TTC
    2008: HSG (normal), couple rounds of clomid through gyno
    2008 - 2010: dragging my feet out of fear and procrastination
    October 2010: first consultation with RE, dx PCOS and fibroids (DH slightly low count/motility)
    Oct. 2010 - Dec. 2012:  In DENIAL! avoided the issue because I was scared of surgery
    January 2013: returned to RE, fibroids grew significantly
    February 2013: second HSG, fibroids pushed on tubes which blocked them somewhat
    March 2013: MRI to determine what type of surgery may be necessary

    July 29, 2013: fibroids (5) removed via robotic laparascopy
    August 2013 - Nov 2013 : benched due to recent surgery

    IUI #1, Dec. 24, 2013, BFN 
    IUI #2, Jan. 25, 2014, BFN
    IUI #3, Feb. 25, 2014  BFN
    IUI #4 canceled due to lack of response to letrozole
    IUI #4.1 April 28, 2014, BFN

    May 16, 2014: wtf consult, start prepping for IVF in June and add injects for one last IUI in the meantime
    IUI #5 started letrozole and bravelle but canceled after HSG led to new diagnosis

    May 21, 2014: third HSG, tubes blocked, one at the beginning, one hydrosalpinx??
    June 11, 2014: consult, approved to move on to IVF because the hydro is not completely blocked therefore allowing fluid to move through slowly rather than backwards
    IVF #1 August 8, 2014 - 3dt of 2 embryos, BFN
    September 17, 2014 - 4th HSG, the right tube is very patent (open!!) dye went straight through this time. Weird!
    October 2, 2014 - started metformin treatment
    November 14, 2014 - blood work, brought A1C down from 5.8 to 5.5

    November 26, 2014 - RE finally back from vaca and reviewed my chart, no more IVFs for rest of calendar year
    December 1, 2014 - Right after Thanksgiving, I called a new clinic and got in right away! Plan for IVF
    December 17, 2014 - ER! 29 retrieved (!!), 16 mature, all 16 fertilized (ICSI)

    IVF #2 December 20, 2014 - 3dt of 3 embryos, BFN

    We are done with treatment unsuccessfully. :(


    PAIF/SAIF/All Welcome!

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    So even though I'm triggering, I still have a shot of having the follicles grow a bit more? I know the shot doesn't make me ovulate right away but I wasn't sure if it impeded follicle growth or not.
    Me: 28 Husband:: 29
    TTC  since April, 2012; Diagnosed with Hashimotos, Annovulatory.
    October, 2013- Metformin + 50mg Clomid + iui - BFN
    November, 2013- Metformin + 50mg Clomid + iui + Prometrium 2x a day- Chemical Pregnancy



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    I don't think it does but from what I'm reading online (of course don't know for sure, just what I read) the ovidrel will help boost the maturity a little before ovulating. Plus almost everywhere I've read it seems 18 is what most RE's aim for (mine does as well) so I'm thinking that's what your RE was going for.

    Me: 32  DH: 33  Married: March 2004

    July 2006: started TTC
    2008: HSG (normal), couple rounds of clomid through gyno
    2008 - 2010: dragging my feet out of fear and procrastination
    October 2010: first consultation with RE, dx PCOS and fibroids (DH slightly low count/motility)
    Oct. 2010 - Dec. 2012:  In DENIAL! avoided the issue because I was scared of surgery
    January 2013: returned to RE, fibroids grew significantly
    February 2013: second HSG, fibroids pushed on tubes which blocked them somewhat
    March 2013: MRI to determine what type of surgery may be necessary

    July 29, 2013: fibroids (5) removed via robotic laparascopy
    August 2013 - Nov 2013 : benched due to recent surgery

    IUI #1, Dec. 24, 2013, BFN 
    IUI #2, Jan. 25, 2014, BFN
    IUI #3, Feb. 25, 2014  BFN
    IUI #4 canceled due to lack of response to letrozole
    IUI #4.1 April 28, 2014, BFN

    May 16, 2014: wtf consult, start prepping for IVF in June and add injects for one last IUI in the meantime
    IUI #5 started letrozole and bravelle but canceled after HSG led to new diagnosis

    May 21, 2014: third HSG, tubes blocked, one at the beginning, one hydrosalpinx??
    June 11, 2014: consult, approved to move on to IVF because the hydro is not completely blocked therefore allowing fluid to move through slowly rather than backwards
    IVF #1 August 8, 2014 - 3dt of 2 embryos, BFN
    September 17, 2014 - 4th HSG, the right tube is very patent (open!!) dye went straight through this time. Weird!
    October 2, 2014 - started metformin treatment
    November 14, 2014 - blood work, brought A1C down from 5.8 to 5.5

    November 26, 2014 - RE finally back from vaca and reviewed my chart, no more IVFs for rest of calendar year
    December 1, 2014 - Right after Thanksgiving, I called a new clinic and got in right away! Plan for IVF
    December 17, 2014 - ER! 29 retrieved (!!), 16 mature, all 16 fertilized (ICSI)

    IVF #2 December 20, 2014 - 3dt of 3 embryos, BFN

    We are done with treatment unsuccessfully. :(


    PAIF/SAIF/All Welcome!

    image    image
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    Thanks- Im just a bit confused because it seemed like standard procedure was to trigger after follicle size reached 18, and mine is triggering at 16, but maybe I just misunderstood
    Me: 28 Husband:: 29
    TTC  since April, 2012; Diagnosed with Hashimotos, Annovulatory.
    October, 2013- Metformin + 50mg Clomid + iui - BFN
    November, 2013- Metformin + 50mg Clomid + iui + Prometrium 2x a day- Chemical Pregnancy



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    image
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    My RE doesn't usually tell me to trigger till my follies are around 20mm but my follies also mature fast and get to 24 by day 12-13 of my cycle. I think they base it on the person. I've missed triggering because my US was on day 12 and I was already ovulating. She may just want to make sure that you don't miss your window to trigger.



    ********Siggy/Ticker Warning***********



    Me (35) no known issues DH (37) MFI. TTC 21 months (24 cycles)
    Dx MFI with low to normal count, low motility, morphology 3%
    HSG normal, ultrasound and labs on me all normal. 

    1 cycle of Clomid 50mg and TI, unmonitored by OBGYN= BFN
    1 cycle of Clomid 50mg and IUI, unmonitored by OBGYN= BFN
    Started seeing an RE!!
    2 more cycles of clomid 50mg (great response), with IUI and Pregnyl trigger (4.8-8 mil good ones after wash) = all BFN
    1 cycle of clomid 50mg (3-7) followed by Follistim 75iu (7-11) + IUI = BFN
    December 2013 DH saw urologist and is taking Anastrozole, CoQ10, and L-Carnitine
    IUI #5 natural cycle (needed a med break) = BFN
    IUI #6 Follistim 75iu (CD3-10) + Pregnyl (CD11) + IUI (final count after wash 300K) = BFN
    IUI #7 Follistim 75iu (CD3-9) + Pregnyl (CD11) + IUI on 2/20 (post wash count 12.5 million)= BFN
    IUI cancelled (DH OOT) Clomid 50mg (CD3-7) 1 follicle +(not well timed) TI = BFN
    IUI #8 and last one!! Clomid 100mg (CD3-7) +OPK before US + IUI 4/17 (post wash 8.5 mil)= BFN

    Pre-IVF testing complete! SHG great and measurements taken! Labs for infectious diseases completed, FSH (5.4), TSH (1.6), Prolactin (11), AMH (2.6), Estradiol (40).

    Started BCP 5/29 and Lupron 6/11 prep for IVF #1! Started follistim 225u/day on 6/28. Monitoring on 7/2 >15 follicles measuring 11-14, E2 758. Monitoring on 7/5 all ready to go!! Great follicle sizes and lining is at 9. Tigger 7/5, ER 7/7 16R 9M 3F. Stimmed too fast in just 7 days. 7/10 3dt of 2 8-cell grade 2 & 4. 7/14 P4 >60.
    Holy crap BFP!!!
    Beta #1 (14dpo) 7/21 112 Beta #2 (16dpo) 7/23 286 a Beta #3 (18dpo) 7/25 761 Beta #4 (21dpo) 2631!!! Hold on tight little embies!!
      First Ultrasound 8/7- 1 perfect little bean with a beating heart 117bpm!! EDD 3/30.
    Second ultrasound 9/2 Little bean measuring a few days ahead with a heart rate of 161!



    PAIF/SAIF/All Welcome!

    image




    Pregnancy Ticker




    March 15 Siggy Challenge: You had one job

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    It does sound a little early, but a 15 and 16 could be mature. I think that 18-22 is the range that most doctors use though. Maybe you had some in the 12-14 range too that he didn't want to give time to catch up. You could ask about it next cycle if this one doesn't work.

    Baby Birthday Ticker Ticker

    TTC since Sept 2011, Unexplained IF
    Oct 12 - Jan 14: 3 clomid/TI cycles, 2 hysteroscopies, 2 IUIs, 1 BFP (MMC @ 12w), 2 more IUIs
    Feb 14: Gonal-f + IUI #5 = BFP! (EDD 11/4/14)
    Baby boy arrived 11/13/14!

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    I triggered last night, and my follie sizes yesterday were 17 and two 15s. They said they warn anyone with a 15 or larger for the risk of multiples. They should grow a bit more before releasing. Good luck to you!

    image
    TTC since March 2012
    DX: MFI (4% motility)

    Cycle 13: Natural cycle w/ HSG test = BFP
    Identical twins! 
    Lost my angel boys at 10.5 weeks

    Cycle 14-16: Natural Cycles = BFN
    Cycle 17: Follistim + Trigger + IUI = BFN
    Cycle 18: Natural Cycle = BFN
    Cycle 19: Follistim + Trigger +IUI#2
    Polyp found: SIS 11/11 - hysteroscopy 11/14
    Cycle 20: Follistim + IUI#2 = BFFN
    Cycle 21: Follistim (adj. dosage) + IUI#3 TI  = BFN
    IUI cancelled due to weather
    Cycle 22: Follistim + IUI#3.1 = BFN

    Cycle 23: treatment break, IVF consult
    Cycle 24 - 26: natural cycle w/ acupuncture + Chinese herbs = BFN
    Cycle 27: Follistim + IUI#4 = BFFN
    Natural Cycles until IVF
    Cycle 30: IVF#1 - Starting with Menopur + Follistim + Ganirelix
    17 retrieved, 12 fertilized, 5dt w/ 2 blasts, 5 frosties

    Betas:  #1-156(9dp5dt), #2-1200(13dp5) #3-6112(17dp5)
    Ultrasound #1 10/6: 1 bean!
    TEAM BLUE!

    My Chart
    ~~ALL WELCOME~~

    BabyFruit Ticker
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    DharmaChickDharmaChick member
    edited February 2014
    The decision was likely based on your rate of growth and the number of follies, which varies a lot from person to person.  My RE waited until after I was at least 18mm, b/c there was only one follie and it was growing slowly.
    ________
    ME: 34, Atypical PCOS (lean, no O without meds) + unexplained; DH: 33, mildly low motility
    09/2012: Start TTC after stopping NuvaRing.  No cycles seemed to occur.
    01/2013 - 05/2013: Tried Provera to "jumpstart" cycles. No luck.
    12/2013-
    01/2014: Clomid 50mg - no big follies, stepped to 100mg; One mature follie, Ovidrel (HCG trigger), IUI #1 completed - BFN
    02/2014: Clomid 100mg;
    One mature follie, Ovidrel trigger, IUI #2 completed, Crinone - BFN
    03/2014: Clomid 100mg -
    no big follies on 1st round, 2nd round prescribed; One mature follie, Ovidrel, IUI #3 completed, Crinone - BFN
    04/2014-05/2014: Letrozole 5mg + Ovidrel HG to prep for IUI #4 switched to TI, Crinone - BFN
    05/2014-06/2014: Letrozole 5mg; one mature follie,
    Ovidrel, IUI #4.1 completed, Crinone - BFN
    07/2014-08/2014: Letrozole 5mg; one mature follie,
    Ovidrel, IUI #5 completed, Crinone - BFN
    09/2014-10/2014: IVF Prep - Insurance requires IUI #6;
    Letrozole 5mg - no big follies 1st round, 2nd round prescribed; IUI #6, Crinone - BFN
    11/2014: "Break" - Letrozole 5mg to cycle before prepping for IVF - successfully O'ed, but BFN
    12/2014: Extending 'break' one more Letrozole-only TI cycle for mental health break - BFN
    01/2015-
    02/2015: Prep for IVF - BCP then Gonal-F, Ganirelex, Novarel trigger;  ER scheduled 2/11!
    http://www.fertilityfriend.com/home/4cf919
    PAIF/SAIF Welcome.
    December 3T Siggy Challenge: Favorite Holiday Movie
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    You didn't mention your e2 levels.  That plays into when to trigger as well.  
    Me 38 DH 40
    TTC since Dec 2010.
    Diagnosed anovulatory, HSG clear. Slight MFI- borderline count, but excellent motility and morphology 
    Nov. 12- Feb.13 Gonal F + Ovidrel + IUI = BFN
    Lap April 13. Found blocked tube and bridged fimbria. Opened tube and cut fimbria. All clear 
    June 13  Gonal F+ Pregnyl +IUI = BFN Stopped treatment with RE due to side effects from drugs and told we needed IVF.
    Oct. 13 started Accupuncture and Chinese herbs- being monitored by RE. Getting better response- e2 and follie size. 
    Now RE says TI till March, then IUI. Fingers crossed, 

    All welcome
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