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Early E2 levels

Milagros315Milagros315 member
in Infertility
I saw a recent post about E2 levels towards the end of stimming which was really helpful, but I was wondering if anyone knows what they're looking for in the earlier stages. I've seen a few things say 75 on day 3 is good, but a few others said between 100-300. I'm guessing it depends on how many follicles you have, so is the number itself really important in the beginning or just the rate of change?

My E2 on day 4 was 186 and I was told to keep doing the same thing. I was just curious about how they determine what to do next.
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Married July 2011 * TTC #1 since 8/12 * Me: 29 DH: 29
21 Cycles TI: BFNs
DX: Stage 2 Endo, uterine polyps and paratubal cysts removed
2/14: IVF #1 Lupron Protocol = 12R/10M/9F, no frosties; transferred one 3BB blast = BFN
4/14: IVF #2 Antagonist Protocol = 18R/16M/15F/6 frosties; transferred one 4BB blast = BFP!!
Beta #1 (5/12) = 232 Beta #2 (5/16) = 886 Beta #3 (5/20) = 3168
EDD 1/18/15 It's a BOY 

~~~~~~ All Are Welcome ~~~~~~

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Re: Early E2 levels

  • healz413healz413 member
    I don't have the answer to your question, but rather I have a similar question as well. My e2 levels one day 4 (today) were only 71 and my RE was not happy about that and is concerned about my lack of response since I'm already on max dose of stims. So I would also appreciate insight from anyone. (I have a good AMH and AFC, so my RE was expecting that I would respond well.)
    ****loss discussed*****

    We're queer. I'm 33, have severe stage 4 endo, and had both fallopian tubes removed. My love ("Manada" on the boards, 32) was diagnosed with diminished ovarian reserve. We did Partner IVF (my eggs, her uterus). We lost our twins Tavin and Casey at 21 weeks gestation.

    Our IUIs
    with @Manada: IUI# 1-7 (December 2012- September 2013) all BFN. Tried natural, femara, clomid, puregon/follistim, clomid and menopur combo, both the ovidrel and HCG triggers.

    Our IVFs:
    IVF #1 my eggs November/December 2013: Cancelled IVF due to poor response

    IVF #2 my eggs/Manada's uterus January/February 2014
    BCPs and lupron overlap Stimmed: 1/22-2/2: Bravelle and Menopur (dosage ranged from B300 and M150 to B375 and M150 to B300 and M225)
    2/4 retrieved 10 eggs. Endo was much worse than expected. Only 3 eggs fertilized; February 7 transferred two day 3 embryos, froze one. All great condition.
    BFP eve of 6dp3dt; Beta 1 (11dp3dt): 110; Beta 2 (13dp3dt): 175; Beta 3 (15dp3dt): 348; Beta 4 (19dp3dt): 2222; Beta 5 (21dp3dt): 4255
    1st ultrasound (3/6  6w 1d): TWINS!!!! Twin A measuring 6w1d with a heartbeat of 118bpm. Twin B measuring 6w0d with a heartbeat of 113bpm. 

    ***July 18, 2014 we lost our beautiful babies at 21 weeks gestation. They were born too early. Tavin Sara T. and Casey Elizabeth T. are beautiful and precious and we will love them and miss them forever.***

    FET #1 December 2014
    Intralipid infusion on Dec 10. Transfer of 1 day 3 nine-cell embryo into my uterus on Dec. 19. (acupuncture immediately before and after)
    BFP on Dec. 27; Beta 1 Jan 2 (14dp3dt): 665, Beta 2 Jan 4 (16dp3dt): 1859, Beta 3 Jan 6 (18dp3dt): 4449, Beta 4 Jan 10 (22dp3dt): 12,251.



      Lilypie Angel and Memorial tickers
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  • Milagros315Milagros315 member
    @healz413 - I'm sorry that you're having some concerns. I have heard that a slow rise may be a good thing, so I hope that you just need some extra time to respond! Hopefully someone here can give you some insight. Good luck!
    ******************************************** siggy warning ******************************************

    image image

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    Married July 2011 * TTC #1 since 8/12 * Me: 29 DH: 29
    21 Cycles TI: BFNs
    DX: Stage 2 Endo, uterine polyps and paratubal cysts removed
    2/14: IVF #1 Lupron Protocol = 12R/10M/9F, no frosties; transferred one 3BB blast = BFN
    4/14: IVF #2 Antagonist Protocol = 18R/16M/15F/6 frosties; transferred one 4BB blast = BFP!!
    Beta #1 (5/12) = 232 Beta #2 (5/16) = 886 Beta #3 (5/20) = 3168
    EDD 1/18/15 It's a BOY 

    ~~~~~~ All Are Welcome ~~~~~~

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  • Areej76Areej76 member
    Hi ladies! My estrogen levels were around 1000 on day 3 of stims and my nurse commented that it was a great response but then they lowered my dosage of gonal f from 250 to 150. I trigger tonight and its in the low 2000s and my RE and nurses were ecstatic. I hope this helps. Good luck xo
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  • beachy6beachy6 member
    Are you on day 3 of stims or cd3? If you are on day 3 of stims, I think you are right where you are supposed to be! My RE wanted mine between 100-300, so your number sounds perfect!

    BabyFruit Ticker

     ttc #2 since 2004 Me (35): Stage 3 Endo, DH (34): High DNA Frag

    IVF/ICSI #2: April 2014: BFP!!!!!!

    ET of 2 great quality embryos. + BFP on 9dp5dt. Beta #1 (10dp5dt): 257, Beta #2 (14dp5dt): 1561,

    Beta #3 (21dp5d5): 8,172. Wow. It seems this is actually working. Shocked beyond belief.

    1st u/s @6w5d: Baby A hb 124, Baby B hb 127 (Both measuring perfectly!)

    Lost baby A. Praying that baby B stays healthy. Baby B hb 175 at 11 weeks

    It's a GIRL!!!

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  • Milagros315Milagros315 member
    beachy6 said:
    Are you on day 3 of stims or cd3? If you are on day 3 of stims, I think you are right where you are supposed to be! My RE wanted mine between 100-300, so your number sounds perfect!
    That number was after 3 days of stims. I guess my doctor goes with the 100-300 range too. Thanks for your reply! 
    ******************************************** siggy warning ******************************************

    image image

    image

    Married July 2011 * TTC #1 since 8/12 * Me: 29 DH: 29
    21 Cycles TI: BFNs
    DX: Stage 2 Endo, uterine polyps and paratubal cysts removed
    2/14: IVF #1 Lupron Protocol = 12R/10M/9F, no frosties; transferred one 3BB blast = BFN
    4/14: IVF #2 Antagonist Protocol = 18R/16M/15F/6 frosties; transferred one 4BB blast = BFP!!
    Beta #1 (5/12) = 232 Beta #2 (5/16) = 886 Beta #3 (5/20) = 3168
    EDD 1/18/15 It's a BOY 

    ~~~~~~ All Are Welcome ~~~~~~

    Report Reply
  • violetmarie61516violetmarie61516 member
    I think E2 levels also depend on how many follicles you are starting out with.  If you normally have a high AFC before starting, I think they would want your levels to be higher than if you had a very low AFC.  Good luck!
    TTC #1 Since May 2011 ~ Everyone Welcome
    Me (34): DOR d/t chemo/radiation, Immature Endometrial Lining, Hypothyroidism
    DH (35): MFI d/t testicular torsion and removal, Low T, Oligospermia, Anti-Sperm Antibodies, Currently on T supplements
    Sept '11-April '13 ~  Testing, failed multiple MFI treatments, saving & TONS of praying
    January 2014 ~ IVF/ICSI & PGS ~ no response to stims ~ converted to IUI ~ BFN
    February 2014 ~ On to donor embyros ~ 5 blasts!!! 
    March 2014 ~ FET #1 ~ Transferred 2 blasts ~ BFN
    July 2014 ~ Kliman's mock cycle with endometrial function test
    Sample too small for EFT, HE slide showed immature cells
    New protocol planned, saving for another biopsy for EFT
    January 2015 ~ Considering adoption options
    April 2015 ~ Privately arranged adoption of planned pregnancy
    DD#1 ~ Lillyana Violet Marie born 6/15/16, Finalized adoption 12/20/16
    July 13, 2018 ~ BFP....WTF?!?!
    7/16 Beta #1 ~ 466...7/18 Beta #2 ~ 1,077...7/23 Beta #3 ~ 5,291
    7/23 US #1 ~ 1 gestational sac seen and yolk sac
    7/30 US #2 and 1st OB appt ~ 1 perfectly round gestational sac, 1 perfect yolk sac and 1 teeny tiny heart beat seen!!!
    Lilypie Maternity tickers


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