Success after IF

Pio Problems, wwyd?

ladybug2785ladybug2785 member
edited January 2014 in Success after IF
Hello ladies. I just had a FET and it was successful. I am currently 6 weeks and I am taking low dose aspirin, extrace, and doing the pio injections until I am 10 weeks.

The problem is that the pio has left knots all over my lower back and hip area. I hate to complain because I am so lucky to have had a successful cycle, but the pain is terrible. It's starting to spread to the front of my hips and down my legs. I think all the knots are causing my body temperature to be high too, it's been around 99.4 today.

DH thinks I should call and ask for something else progesterone wise, but I hate calling and asking about anything because the nurses tend to be a little rude.

I go in on Tuesday for my first ultrasound, so I wanted to wait it out until then but the high temperature worries me. Any advice or experience with this?

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Re: Pio Problems, wwyd?

  • I was on PIO shots with my first cycle. Couple of questions/suggestions for you that might help. Make sure not to ice the PIO and I would warm the vial in my hands before injection and it would help. Also after the injection I rubbed the injection site for a couple of minutes and sat on a heating pad for 15 minutes. Hope this helps I never had any problems. Maybe your allergic or could you try the suppositories? They are more expensive and messy but easy to use.

    Me 38 MH 41 - TTC since June 2010 - dx with Severe MFI. Straight to IVF with ICSI. IVF #1 - ER 06/13/12 - 9 Eggs Retrieved - 4 ICSI'd - only 2 fert. 06/15/12 - 2DT - 3 cell & 6 cell with fragmentation. Beta 06/29/12 - IVF #1 = BFN. 07/20/12 - WTF Appt -Told by our RE to quit IVF. Second Opinion from RE is good. IVF#2 - November 2012. Estradiol Pills Started 11/6. Stims start 11/16. ER 11/26 - 7 eggs retrieved - all mature. 4 fertilized with ICSI. ET 11/29 Transferred 3 embryos. Beta is 12/10. 1st Beta 81 2nd Beta 160 and 3rd beta 360!!! First U/S 12/21/12 - We saw one beautiful gest. sac. 2nd U/S is 01/04/2013 - H/B 183 02/05/13 - NT Scan - everything looks good and IT'S A BOY!  Aiden was born 08/20/2013.

    IVF #2 is in progress.  ER was 05/12/14 - 11 eggs retrieved, 8 fertilized with ICSI.  ET was 05/15/14 - we transferred 3 embryos as we did on the cycle my son was conceived.  We were able to freeze 3 embryos. Beta is scheduled for 05/26/14.  1st beta - 111.  2nd beta - 159 didn't double :( 3rd beta Friday 5/30) - not a lot of hope left. Beta # 3 is 247 - probably ectopic.  Beta # 4 is 813 - possibly vanishing multiple sydrome?  06/05/14 - 5w4days - first U/S - we see a gestational sac and yolk - still have hope!  06/17/14 - 7w1day - U/S and saw and heard the heartbeat - Finally!  06/27/14 - 8w4days - Baby and heartbeat look and sound great :)  EDD 02/01/14 and It's a boy!


     "Everything will be okay in the end. If it's not okay, it's not the end."


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  • Hi -
    I'm 5w 3d and also on PIO. It's horrible, last time I had the same issues you were having, but this time it's been easier for me. I'm not entirely sure if this is the reason I found out last time, several weeks in, that I'd been injecting too low.  This time I had them draw the circles (I inject myself) and I've only had one knot and in retrospect, I think I may have injected too low. SO make sure you are injecting into the right spot!
    Other helpful hints:
    1. warm the oil up - I run it under hot water, or stick the whole vial in my bra until it's warm
    2. Inject really slowly and leave the needle in for 10 full seconds after all of the oil is out of the needle.
    3. like PP said - definitely rub it in after and use a heating pad.
    Honestly, last time (my second time on PIO) I was convinced I'd developed a new allergy... but I didn't because I'm totally fine now with my new system.
    HTH!


  • Sorry this is happening! I second the rubbing, hard for a few min, also make sure your relaxed, if your tense it can cause more pain, and the heat pad is a dream...
    As far as the temp, its not too high yet to worry, 101.4 is when they tell me to call in... So try a cool shower or some tylenol and relax a bit! :)
    Also baby can be the cause of your temp to rise, mine always goes up pregnant! (By always i mean last time with my son, with my loss, and this time! )

    Good luck!

    Started TTC in 2006, LOTS of trying, and trying, and 7 rounds of IVF with 13 embryos, 2 perfect little boys and 5 loses....
    All finished with babies, started to make diet changes, Keto, to be MORE for my kids, lost 30 pounds, still going, and 3 months in, I had a natural cycle, and then ovulated... Hubs and I are going to see what happens now... Maybe a natural pregnancy? After everything we have been through? Or just a return to normal hormones? We shall see what the future holds!

    Baby Dust To All!!!

  • Yeah, PIO sucks. Definitely rub the injection site hard after the shot and then use heat. I would leave the heat on for a while. Congratulations!
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    Unexplained Infertility

    After two Clomid cycles, three injectable IUI cycles, two IVFs, two miscarriages, and one lap surgery, IVF #2 has brought us our little boy!

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    TTC #2
    After months of being postponed or cancelled, FET #1.3 (Natural FET) brought us twin girls!

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    Surprise! Baby #4 is due in March!
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