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Autoimmune ladies - or anyone taking Prednisone in first tri? [Intro}

DawnHopeDawnHope member
in High-Risk Pregnancy
Hi ladies,

Looks like I'll be joining you, if you'll have me.  I am 6 weeks 6 days today.  My history is in my siggy (though it won't let me update my most recent news) but I am 42 with a rare autoimmune disease (suspected Behchet's), Factor V Leiden (hetero) and have had 5 miscarriages.  Most were very early, but I had one last year after seeing the heartbeat which was likely linked to an autoimmune flare.  I started getting high fevers and no one could figure it out, and I miscarried soon after.

With this pregnancy, after extensive research and debate, we have been on a low dose of Prednisone that was started a few weeks prior to transfer. I do attribute it to our success thus far.  My RE doesn't think I need to continue it, but I feel like I should stay on through first tri. Do any of you have any experience with this?  Would love to hear any stories, if you are willing to share.

Thank you!
Me-42 DH-43 TTC #1 since 3/11
HSG 7/11 showed possible blockage
8/11 BFP, then early m/c  (Natural)
9/11 blood tests reveal Factor V Leiden (heterozygous)
11/11 Hysteroscopy revealed uterine septum, which was repaired
12/11 1st round of Clomid (100mg)=BFN
1/12 2nd round of Clomid (100mg)=BFN 
2/12 Repeat HSG=All clear 
2/12 IUI with injectables #1=BFN 
3/12 natural cycle=BFN 
4/12 IUI with injectables #2=C/P 
7/12 IVF #1=30ER, 9F, 3T, 1 Frostie 7/29=BFP! 
8/27/12 No Heartbeat. Waiting to M/C 
9/13/12 D+C
12/12 Operative Hysteroscopy 
1/31/12  IVF#2 ...BFP 2/6 m/c 2/12 methotrexate due to presumed ectopic
July '13 IVF #3: 13R, 10M, 8F=BFP
1st Beta=549  2nd Beta 594 3rd Beta 422. M/C #5
IVF#4 in November=BFP…TWINS!!!!!

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Re: Autoimmune ladies - or anyone taking Prednisone in first tri? [Intro}

  • gfam23gfam23 member
    I have an auto immune disease (myasthenia gravis) and was on 10-20 mg of pred my entire first pregnancy. They may keep you on it or wean extremely slowly. All was fine with it for me (other than the usual fun pred side effects).
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  • socialwkrsweetiesocialwkrsweetie member
    edited December 2013
    Although I'm not currently pregnant, I also have been on prednisone with both of my MMCs. Due to my lupus I will have to remain on it throughout my pregnancy. My dr said that if it goes above 60mg that's when there is more concern it can cause possible issues with the baby but my MFM agrees the control it provides over my autoimmune issues outweighs the risk. And I'm currently on 10mg. Good luck!

    Me: 31 * DH: 33 * TTC since Sept 2012
    Hx of Pulmonary Embolisms, Right Sided Heart Failure and Nephrotic Syndrome 2001
    Dx w/ Hashimotos 1998 * Dx w/ Systemic Lupus 2005 * Dx w/ PCOS 2012
    Began working with RE Dec 2012February 2013: Clomid 100mg + Ovidrel  BFP # 1: 2/26/13 * EDD 11/9/13 * MMC at 7w5d -- 3/27/13 * D&C 3/28/13May 2013: Clomid 100mg + Ovidrel + PIO + Lovenox  BFP # 2: 6/6/13 * EDD 2/18/14 * MMC at 11w1d -- 7/31/13 * D&C 8/1/13RPL Testing & Karotyping was normal for both of usEmbryo testing was inconclusiveBenched July 2013- January 2014 due to Lupus FlareWTF appt 2/12/14IVF is OUT and Clomid + Ovidrel + Endometrium is in... AGAINBFP # 3: 2/28/14 * EDD: 11/12/14 * CP 3/1/14TTC on our own until April 2014*A persons a person no matter how small*
    My Ovulation Chart
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    *All PgAL/PAL Welcome*


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  • DahliaFlowerDahliaFlower member
    I did take predinsone through the first trimester for suspected autoimmune factors leading to recurrent pregnancy loss.  As I recall, I began the wean around 12 weeks or so, and it took me more than a week or two to come off.  

    I believe that the predinsone was a major factor in my having a successful pregnancy resulting in the delivery of a very healthy litttle boy!  I would absolutely do it again.  

    PM me if you want to discuss further.  
    TTC #1 12/2009
    BFP #1 1/2010, M/C 6 weeks
    BFP #2 6/2010, DD lost to     congenital heart disease, we are heartbroken.

    TTC #2 4/2011, diagnosed MTHFR, FVL
    Four natural cycles BFN; Clomid IUI BFN; Follistim IUI BFN;
    1/2012 IVF #1 BFN
    4/2012 FET BFP #3
    5/2012 7w1d u/s: anembryonic demise; M/C @ 8w.
    6/2012 found Stage II/III endo on laparoscopy, removed w/ laser.
    8/2012 IVF #2 epic fail: no viable embryos.

    Vacation, break, second opinions, on to new RE.
    1/2013 Surprise chemical pregnancy BFP #4 (break cycle), IVF #3 postponed.
    2/2013 TI w/ hormonal support, prednisone, aspirin, Lovenox, acupuncture gave us a miracle BFP #5!
    Heartbeat on U/S at 6w1d!     Baby,please stay!!
    Our miracle baby boy arrived 10/2013!  We are so in love!!

    10/2014 Surprise BFP #6
    Our second daughter arrived in May 2015!  We are so grateful!  

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  • cullentrcullentr member
    I was on it for first ten weeks due to autoimmune factors and recurrent pregnancy loss.
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