Infertility

E2 range?

FloridaSun82FloridaSun82 member
edited December 2013 in Infertility
Does anyone know the normal range of E2 throughout the IVF process? I had an u/s yesterday, after 7 night of stims and it showed 1 11mm follicle and the rest under 10. The nurse counted about 15 in the 8mm range, and a slightly less at 9mm. I'm discouraged, it should be moving along faster than it is. My E2 was 171, which seems pretty low to me, but I don't know what the norm is. The doctor isn't changing my dose of meds yet, since my E2 has more than doubled in 2 days. I don't know why I thought my body would respond like it should to stims, when it hasn't responded to anything else that I've done...
Me (31) - PCOS with insulin resistance

4 rounds of Clomid = no response
IVF # 1 - ET (1 3AA, 4 frosties): 12/22 = BFP
EDD: 9/9/2014

Re: E2 range?

  • :( Sorry you are going through this. I'm not big on the numbers but I know once your follicles become around 19mm, your E2 should roughly 200 for each mature follicle. When they are small, it's hard to tell. My E2 was about the same when mine were all under 10, but they increased my dosage after that. Did they increase your dosage? 
    FX they all grow lots and lots by the next monitoring appt.
    ***WARNING***

    TTC Since 12/2008;  DH: 32, Azoospermia     me: 33, DX during IVF #4: Low AMH (Normal FSH) / SER due 
    to IVF Meds (causing failure to fertilize) Recent DX: Hashimoto's, Lupus Anticoagulant, White Blood Cell Disorder 
    High ANA, ATA, & APA, PAI-1 Heterozygous= blood clotting disorder; connective tissue disorder 
    IVF w/ ICSI #1 2/2011     IVF w/ ICSI #2 5/2011    IVF w/ ICSI #3 12/2012   *New RE* IVF w/ ICSI #4  5/2013
    IVF w/ ICSI #5 8/2013 (Natural Cycle- No drugs)- One follicle->one blast. CCS normal. FET 9/10- 6BB blast. m/c @ 5w
    IUI #1 12/23- BFN  IUI #2 Cancelled (ovulated during AF)  Prep:CoQ10 (300 mg); DHEA (25 mg); Melatonin (3 mg), Folgard 2.2, Metformin 500 2x, Levothyroxine 50mcg, Aspirin 81mg w/ calcium, B12,  Vit. D 4000 & Prenate Elite Daily; Cabergoline 1/2 pill 2x week-  Cycling: Estrace Priming; Prednisone 10mg, Lovenox 40mg 2x,  Femera & Menopur   
    IUI #2.1 6/30 & 7/1. 1st Beta: 90 (7/15); 2nd Beta: 226 (7/17); 3rd Beta: 766   EDD: 3/23/2015

       **ALL WELCOME**                                    My Blog 
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  • My E2 stayed pretty low last cycle until I finally had some growing follicles, around 15mm. I've heard the same as mentioned above, that it should be about 200 per mature follicle.
    Pregnancy Ticker

    TTC #1 since June 2012
    Me (28) - DOR (AFC <10, undetectable AMH, >10 FSH), homozygous E429A MTHFR
    DH (29) - MFI low count and morphology

    September 2013 IUI#1 - Clomid + Trigger + IUI = BFN
    October 2013 IUI#2 - Letrozole + Menopur + Trigger + IUI = BFN

    Nov 2013 IVF/ICSI #1 - Protocol: BCP prep, high doses Menopur and Bravelle (12 days), ganirelex
    Results: 5 retrieved / mature, 4 fertilized, 1 arrested and 3 complex abnormal after day 3 PGS = Cancelled after ER
    Jan/Feb 2014 IVF/ICSI #2 - Protocol: Estrogen priming, high doses Menopur and Bravelle (11 days), microdose lupron
    Results: Cancelled after 11 days of stims due to low response and E2 levels
    Feb 2014 IVF/ICSI #3 - Protocol: No prep, low dose Menopur (6 days), ganirelex, Bravelle booster with trigger
    Results: 1 retrieved / 0 mature = Cancelled after ER

    Officially moving on to embryo adoption! We used and love Embryo Adoption Services of Cedar Park
    October 2014 FET #1 - BCP/Lupron/Estrace/Prometrium, transferred 2 of 4 from match #1, BFN
    December 2014 FET #2 - BCP/Lupron/Estrace/Prometrium, transferred 2 of 4 from match #1, BFN
    March 2015 FET #3 - BCP/Lupron/Estrace/Prometrium, transferred 2 of 6 from match #2, BFN
    May 2015 FET #4 - BCP/Lupron/Estrace/Prometrium, lost 2 to thaw, transferred 2 of 6 from match #2, BFN
    October 2015 FET #5 - Natural cycle, lost 1 from match #3 and 1 from clinic backup to thaw, transferred 1 backup, BFN
    February 2016 FET #6 - Natural cycle, transferred 1 from match #4, B FREAKING P!
    Beta 1 = 162, Beta 2 = 316, doubling just over 48 hours

     

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  • Ditto PPs, 200 per mature follicle is normal. Mine was right around where yours is before my follies started
    really growing.
    Me: 30 DH: 30 ~ TTC #1 Since August 2011 
    BFP #1 2/28/13, Ectopic, Tubal surgery 3/25 
    Began RE testing 8/8, Dx Unexplained, 
    IUI #1 11/1=BFN Moving on to IVF 
    IVF #1 12/2 ER 8R 7M 4 fertilized
    12/7 Transferred 2 "perfect" little blasts 12/17 BFN
    New DX= DOR, I fu*kng hate IF
    1/14 Hysteroscopy, new clean uterus!
    IVF #2: bcp, Lupron, follistim 300, menopur 225. 2/21 8R 4M 3F. 3dt of 2 perfect embryos. 1 little penguin 
     3/10 BFFN
    Regrouping. Seeing reproductive immunologist Dr. Kwak Kim 6/10 
    Kwak Kim protocol: Metformin 1000mg, vitamin D 4000iu, vitamin E 400iu, baby aspirin, Metanx, levothyroxine 75mcgs 
     Surprise BFP 9/21!!! Beta #1 247, Beta #2 630. Miscarried 10/13

  • At this point, it's too soon to tell. A lot can change with those numbers in a day! I have been told a slow, steady rise is actually a good thing. Good luck!!!
    **SIGGY WARNING**

    Me: 32 DH: 35  TTC#1 since March 2012
    Dx: Poor Embryo Quality, Arcuate Uterus, Poor Uterine Blood Flow, Mild Endo, 
           Protein S Deficiency, Sjorgen's Syndrome 

    IUI #1-5: BFN
    Laparoscopy & Hysteroscopy: minimal endo, partial septoplasty
    IVF #1: 10R/6M/6F ~ Day 3 ET = BFN
    IVF #2: 14R/9M/5F ~ transfer canceled ~ all embryos arrested at 1-2 cell stage
    IVF #3: 9R/5M/5F ~ 1 frosty!
    IVF #4 (FET #1): BFN

    IVF #5 (DE IVF #1 with Dr. KK protocol): Currently PREGNANT!!!!!!
    Synthroid + Prednisone + Metformin + Baby Aspirin + Supplements Galore = 15+ pills a day
    Lupron + Lovenox + Delestrogen + IVIG + B/W = 2-5 pokes a day
    19R, 17M, 17F - transferred two Grade A blasts 11/16, four frosties!!!
    Beta #1 11/24 (13dpo/8dp5dt) = 367 ~ Beta #2 11/26 (15dpo/10dp5dt) = 709
    Beta #3 11/29 (18dpo/13dp5dt) = 1,997 ~ Beta #4 12/1 (20dpo/15dp5dt) = 3,403

    imageimageimage

    My Blog: Running and Dreaming for Two ~ All are Welcome!
  • No kidding! I went today, follies are a little bigger but estrogen jumped to 837, only 48 hours since it was 171! Now, they lowered my meds and added ganirelix.
    Me (31) - PCOS with insulin resistance

    4 rounds of Clomid = no response
    IVF # 1 - ET (1 3AA, 4 frosties): 12/22 = BFP
    EDD: 9/9/2014

  • My E2 was slow in rising, and I ended up with OHSS after ER... so you never know. Wishing you the best!
    TTC since May 2012
    Me: 32 H: 31
    DX: MFI-Very Low Count, I have Hashimotos.
    IVF prep September 2013 cancelled due to Ovarian Cyst
    IVF #1 October 2013 Antagonistic Protocol with ICSI  ER 10/31/13 (18R 16M 11F- 6 blasts to freeze)
    ET delayed due to OHSS 
    FET scheduled for July 8. Delayed due to a crazy high TSH (it had been under control for YEARS!)
    FET #1 8/5/14 sET BFN 

    All welcome!
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