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Estrogen Priming IVF Protocol Side Effects

Lady2010Lady2010 member
in Infertility
Hi. Hope everyone had a wonderful Thanksgiving. I am on CD3 of this protocol. I had been using the Vivelle patch for about 10 days and starting last night started 150 Menopur & 300 GonalF. Even before I did the injections last night my husband commented my breast are getting bigger again. I had also noticed the last few days my bras were getting tight again and I was back to wearing more comfortable sports bras. Has anyone else had this problem? I am going to go get a new bra today - but only one or two since I don't want to keep buying new ones every few weeks. Any thoughts or experience are appreciated. Thank you!
***signature/ticker warning***
Me:37 DH:39
TTC#1 since 3/2012

Diagnosis : Unexplained Infertility

3 BFN rounds Clomid + IUI
IVF 1 - BFN, 1 Frozen
IVF 2 - BFN, 5 Frozen
FET 1 - BFP!!! EDD 1/24/15 Beta 1: 700, Beta 2: 2,156; 1st U/S 6w3d: HB 118bpm, 2nd U/S 9w3d: HB 171bpm

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Re: Estrogen Priming IVF Protocol Side Effects

  • Praying4Miracle17Praying4Miracle17 member
    Yep, estrogen will so that to your ta ta's :). I've been on 12mg for about 3 months now to try to increase my lining and my boobs have been super large since. DH of course loves them that way, me not so much! Lol. Good luck!

    **Sig warning***

     

     

    TTC since 9/2011. DH - 32, me 32.

    IUI#1 (natural): BFN; IUI#2 (clomid): BFN; IUI#3 (clomid and follistim): BFN.

    IVF #1 March 2013, freeze all (OHSS).

    FET#1 June: BFN

    FET#2 August: delayed due to thin lining (6.3).  Took a few months off to try and thicken the lining with lots of estrodial.  FET#2.2 December: Cancelled due to thin lining (4.8). Two frosties left.

    *New RE* Sonohystrogram and hystereoscopy done in Feb.

    IVF #2: ER 3/4/14  ET 3/7/14, transferred 3, 3 day 9 cell perfect embryos.  No frosties.

    Beta #1 (14dp3dt) 504

    Beta #2 (21dp3dt) 11,561

    First ultrasound on 4/3/14 showed 3 sacs: one empty and two with beating hearts!!  At 7w2d, found out that one baby did not have a heartbeat anymore.  Praying that baby B makes it.  Baby B is a girl!

    EDD 11/25/14 BORN 11/29/14

    **PAIF/anyone welcomed to comment!!  Thank you.


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  • O2girlO2girl member
    YES!! My tata's were HUGE... Made my DH happy... I actually had to go out and buy bigger sports bras even!
    Me: 38
    DX:  Adenomyosis, Compounded MTHFR, PAI-1 4G variant

    DH: 34
    MFI due to Testicular Cancer

    Married March 2012 <3
    IVF w/ICSI #1
    10 little polar bears
    FET #1 with 2 polar bears ~Nov 6, 2013 BFN :(
    FET # 2 with 2 more polar bears ~March 19, 2014 BFP!!!
    Beta 1= 276
    Beta 2= 662
    4/19/14 ~ baby A became an angel
    5/02/14 ~ baby B became an angel
    5/3/14 ~ D&C
    FET #3 with 1 male polar bear ~October 3, 2014
    October 13, 2014 ~ BFN
    Fur Children:  Memphis 3y, Dutch 3y, Marcel 2y, Meadow 1y



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    January 2015 Siggy Challenge TTCAL
    Animals Interacting with Snow

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  • RunCC37RunCC37 member
    Well, shoot. I noticed no such thing in my tata department!!
    **SIGGY WARNING**

    Me: 32 DH: 35  TTC#1 since March 2012
    Dx: Poor Embryo Quality, Arcuate Uterus, Poor Uterine Blood Flow, Mild Endo, 
           Protein S Deficiency, Sjorgen's Syndrome 

    IUI #1-5: BFN
    Laparoscopy & Hysteroscopy: minimal endo, partial septoplasty
    IVF #1: 10R/6M/6F ~ Day 3 ET = BFN
    IVF #2: 14R/9M/5F ~ transfer canceled ~ all embryos arrested at 1-2 cell stage
    IVF #3: 9R/5M/5F ~ 1 frosty!
    IVF #4 (FET #1): BFN

    IVF #5 (DE IVF #1 with Dr. KK protocol): Currently PREGNANT!!!!!!
    Synthroid + Prednisone + Metformin + Baby Aspirin + Supplements Galore = 15+ pills a day
    Lupron + Lovenox + Delestrogen + IVIG + B/W = 2-5 pokes a day
    19R, 17M, 17F - transferred two Grade A blasts 11/16, four frosties!!!
    Beta #1 11/24 (13dpo/8dp5dt) = 367 ~ Beta #2 11/26 (15dpo/10dp5dt) = 709
    Beta #3 11/29 (18dpo/13dp5dt) = 1,997 ~ Beta #4 12/1 (20dpo/15dp5dt) = 3,403

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    My Blog: Running and Dreaming for Two ~ All are Welcome!
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  • dreamingofdimplesdreamingofdimples member
    I didn't notice anything significant. 
    Me: 36 - stage 2/3 endometriosis, diminished ovarian reserve (DOR), poor responder
    Hubs: 37 - low morphology
    TTC since 2008

    Referred to local RE: 6/22/2010
    HSG + Saline sonogram: 8/13/2010
    IUI #1: BFN 09/2010
    IUI #2: BFN 10/2010
    IUI #3: + acupuncture: BFN 12/26/2010
    Laparoscopy: Diagnosed and cleaned out endometriosis 1/9/2012
    IVF#1 (ICSI): Long Lupron + acupuncture = Cancelled 1/11/2013
    Second opinion phone consult with CCRM: 5/13/2013
    ODWU at CCRM: 6/10/13
    IVF #2 (ICSI): Estrogen Priming Protocol - ER 9/28/2013 = 7 eggs retrieved, 4 fertilized (banked and frozen at one cell stage for PGD testing with embies next retrieval)
    IVF #3 (ICSI): Estrogen Priming Protocol - ER 1/10/14 = 8 eggs retrieved, 3 fertilized. My 4 from previous cycle were thawed at Day 1 to grow to Day 5 blastocyst phase with my 3 fresh embryos. Only 2 embryos made blastocyst and were biopsied for CCS testing. Both were abnormal. Nothing to transfer from either cycle. Told that I should move onto other options.Grieving loss of any biological children with my genes.

    My blog: Dreaming of Dimples

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  • ViasatalyteViasatalyte member
    Yes mine get ridiculous large. I'm already 38d. I hate it.

    Three ectopic preganacies in left tube in 1999, 2003 and 2004. HSG in 2010 concluded left tube blockage. IUI with femara in 2012 BFN. IVF #1 June 2013, 20 retreived, 14 mature, 12 fertilized via ICSI, one transferred, four frozen, BFN.  FET in September 2013 - BFN:( FET #2 April 2014 - BFP!!!!

    Whoever watches the wind will not plant; whoever looks at the clouds will not reap. As you do not know the path of the wind, or how the body is formed in a mother’s womb, so you cannot understand the work of God,the Maker of all things. <?xml:namespace prefix = o />

    Ecclesiastes 11 4:5  

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  • Lady2010Lady2010 member
    Thanks Ladies.  I am glad to hear this is somewhat normal.  And for those of you who didn't have this effect - I am envious!  As others noted - it is not fun / comfortable.

    Wishing you all luck with your cycles!!!
    ***signature/ticker warning***
    Me:37 DH:39
    TTC#1 since 3/2012

    Diagnosis : Unexplained Infertility

    3 BFN rounds Clomid + IUI
    IVF 1 - BFN, 1 Frozen
    IVF 2 - BFN, 5 Frozen
    FET 1 - BFP!!! EDD 1/24/15 Beta 1: 700, Beta 2: 2,156; 1st U/S 6w3d: HB 118bpm, 2nd U/S 9w3d: HB 171bpm

    imageimageimage
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