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Embryo Update

Hi Everyone! I just got a call from my RE's office with an update on our embryos, and I wanted to share.

As a reminder, we started out with 18 mature eggs on Tuesday, 16 fertilized by Wednesday and 15 were still going strong as of yesterday.

So here is the update as of today, with a little commentary on what we can expect next:

* All 15 embryos are still growing and dividing
* 6 of them are now greater than 8 cells
* 7 of them are exactly 8 cells
* 2 of them are 6 cells
* tomorrow they will call us with an update and info about the transfer time for Sunday and instructions for the transfer
* we will talk to the embryologist on Sunday and they will tell us their recommendations for what we transfer based on how they are developing, and then we will decide on Sunday what we will transfer
 
I am super happy with this progress, and really looking forward to Sunday! :)

Me - 30, My wife - 31 , Together for 10 yrs - Married August 2012

5 medicated IUIs w/ RE (March - July 2013) = BFN

Fresh IVF Cycle in September 2013 resulted in 18 mature eggs, 16 fertilized, 12 made it to day 5. Transfer of 2 Grade A blastocysts on 9/15/13, and 10 embryos in the freezer!      *****BFP on 9/25/13 - betas: @10dp5dt = 232; @12dp5dt = 465; @15dp5dt = 1,581   *********William George born June 4, 2014*********

Re: Embryo Update

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    This sounds pretty fantastic so far!! Keeping my fingers crossed for continued great progress.
    ****loss discussed*****

    We're queer. I'm 33, have severe stage 4 endo, and had both fallopian tubes removed. My love ("Manada" on the boards, 32) was diagnosed with diminished ovarian reserve. We did Partner IVF (my eggs, her uterus). We lost our twins Tavin and Casey at 21 weeks gestation.

    Our IUIs
    with @Manada: IUI# 1-7 (December 2012- September 2013) all BFN. Tried natural, femara, clomid, puregon/follistim, clomid and menopur combo, both the ovidrel and HCG triggers.

    Our IVFs:
    IVF #1 my eggs November/December 2013: Cancelled IVF due to poor response

    IVF #2 my eggs/Manada's uterus January/February 2014
    BCPs and lupron overlap Stimmed: 1/22-2/2: Bravelle and Menopur (dosage ranged from B300 and M150 to B375 and M150 to B300 and M225)
    2/4 retrieved 10 eggs. Endo was much worse than expected. Only 3 eggs fertilized; February 7 transferred two day 3 embryos, froze one. All great condition.
    BFP eve of 6dp3dt; Beta 1 (11dp3dt): 110; Beta 2 (13dp3dt): 175; Beta 3 (15dp3dt): 348; Beta 4 (19dp3dt): 2222; Beta 5 (21dp3dt): 4255
    1st ultrasound (3/6  6w 1d): TWINS!!!! Twin A measuring 6w1d with a heartbeat of 118bpm. Twin B measuring 6w0d with a heartbeat of 113bpm. 

    ***July 18, 2014 we lost our beautiful babies at 21 weeks gestation. They were born too early. Tavin Sara T. and Casey Elizabeth T. are beautiful and precious and we will love them and miss them forever.***

    FET #1 December 2014
    Intralipid infusion on Dec 10. Transfer of 1 day 3 nine-cell embryo into my uterus on Dec. 19. (acupuncture immediately before and after)
    BFP on Dec. 27; Beta 1 Jan 2 (14dp3dt): 665, Beta 2 Jan 4 (16dp3dt): 1859, Beta 3 Jan 6 (18dp3dt): 4449, Beta 4 Jan 10 (22dp3dt): 12,251.



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    Don't really know what all that means, but you seem happy, so yay! Excited for your transfer on Sunday!!!
    Baby Birthday Ticker Ticker
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    This is a super awesome report!
    Now the big question: How many are you going to transfer? :-
    We are leaning toward transfering 2... but we probably won't decide for sure until after we talk to the embryologist on Sunday.

    Me - 30, My wife - 31 , Together for 10 yrs - Married August 2012

    5 medicated IUIs w/ RE (March - July 2013) = BFN

    Fresh IVF Cycle in September 2013 resulted in 18 mature eggs, 16 fertilized, 12 made it to day 5. Transfer of 2 Grade A blastocysts on 9/15/13, and 10 embryos in the freezer!      *****BFP on 9/25/13 - betas: @10dp5dt = 232; @12dp5dt = 465; @15dp5dt = 1,581   *********William George born June 4, 2014*********
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    Very exciting news!!!! I'm so happy to see this report. I'll be thinking about you this weekend for the transfer!
    Warning No formatter is installed for the format bbhtml
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    Yay!  How exciting!  I really hope all goes well for you this weekend :) Sticky thoughts your way!
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    KH826 said:
    This is a super awesome report!
    Now the big question: How many are you going to transfer? :-
    We are leaning toward transfering 2... but we probably won't decide for sure until after we talk to the embryologist on Sunday.
    I would say with your age and the way they are growing, transferring 2 is probably going to give you a pretty high chance of twins.  It sounds like you are OK with that, but just wanted to make sure you know going in!

    Yay for the progress report -- things are going really, really well!
    Married my wife 8/2007 ~ TTC #1 since 7/2011
    9 IUIs = 9 BFNs
    IVF October 2012: 22 eggs retrieved, 17 fertilized, 5 frozen
    ET #1: 1 blast = BFP; Blighted ovum discovered at 7w5d; D&E
    FET #1: 1 blast = BFP; Missed m/c discovered at 9w5d; D&E
    Karyotyping: normal ~ RPL Testing: normal ~ Hysteroscopy: normal
    FET #2: 1 blast transferred 10/25; BFP 10/31!
    EDD 7/13/14 ~ Induced at 37w4d due to pre-eclampsia ~ Born on 6/28/14
    *Everyone welcome*

    Baby Birthday Ticker Ticker
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    Thanks, ball.and.chain - we are OK with twins. I know there are risks, and I have been hesitant to talk about transfering 2 b/c I know a lot of people feel strongly against it and I honestly didn't want to attract the negativity (which I know is not why you are mentioning it, btw).... it isn't that we are trying for twins. We are trying for a healthy pregnancy and a healthy baby or babies. We would rather transfer 2 and have twins, than transfer 1 and perhaps have a BFN. I know there are others that disagree vehemently, but this is what feels right for us. My wife and I are both intelligent, educated women and we have done a lot of research. I also have twins in my family, and twin pregnancy does not scare me as much as it scares some. I know there are risks, but there are also many successful, full-term twin pregnancies too. We feel that this is right for us at this point, and whatever is meant to be will be.

    I guess I just had to get that out there in case there was anyone lurking and waiting to pounce and tell me I am stupid and selfish for considering transfering 2... I don't think anyone on this awesome board would do that... but just in case. It is an informed decision, I promise.

    Me - 30, My wife - 31 , Together for 10 yrs - Married August 2012

    5 medicated IUIs w/ RE (March - July 2013) = BFN

    Fresh IVF Cycle in September 2013 resulted in 18 mature eggs, 16 fertilized, 12 made it to day 5. Transfer of 2 Grade A blastocysts on 9/15/13, and 10 embryos in the freezer!      *****BFP on 9/25/13 - betas: @10dp5dt = 232; @12dp5dt = 465; @15dp5dt = 1,581   *********William George born June 4, 2014*********
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    KH826 said:

    I know there are risks, but there are also many successful, full-term twin pregnancies too. We feel that this is right for us at this point, and whatever is meant to be will be.

    It took me a LONG time to get where you are now (mostly due to financial concerns and fear of ending up with triplets, which happened to a friend who transferred 2), but we also finally feel like transferring 2 is right for us.  I'll be honest and say these days I actually kind of WANT to have twins, even though I know it's higher-risk, higher-cost, etc -- I am just SO done with this process and would love to just get the pregnancy part of my life over with (but still have 2 kids).  This is like a 360 from where I was a year ago, but everyone has their own reasons.

    I know you are smart and have done your homework, and that you wouldn't make this decision carelessly...and I also feel strongly that you and your wife can handle whatever comes your way!  Hopefully it will be at least one healthy baby, very soon!
    Married my wife 8/2007 ~ TTC #1 since 7/2011
    9 IUIs = 9 BFNs
    IVF October 2012: 22 eggs retrieved, 17 fertilized, 5 frozen
    ET #1: 1 blast = BFP; Blighted ovum discovered at 7w5d; D&E
    FET #1: 1 blast = BFP; Missed m/c discovered at 9w5d; D&E
    Karyotyping: normal ~ RPL Testing: normal ~ Hysteroscopy: normal
    FET #2: 1 blast transferred 10/25; BFP 10/31!
    EDD 7/13/14 ~ Induced at 37w4d due to pre-eclampsia ~ Born on 6/28/14
    *Everyone welcome*

    Baby Birthday Ticker Ticker
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    KH826 said:

    I guess I just had to get that out there in case there was anyone lurking and waiting to pounce and tell me I am stupid and selfish for considering transfering 2... I don't think anyone on this awesome board would do that... but just in case. It is an informed decision, I promise.

    I lurk around other boards and there are some *nasty* women out there so I definitely don't blame you for your explanation.  FWIW I would definitely do a two-fer myself if I did IVF.  With the cost and everything you went through, you want your BFP!  And your chances are higher with 2 just in case so I get it.  I'd be happy with twins (though I wouldn't necessarily *try* for them) just because I do want 2 kids (maybe 3) so... hey, if I can get 'er done in one fell swoop, awesome :)


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    Thanks everyone! You all rock! :)

    Me - 30, My wife - 31 , Together for 10 yrs - Married August 2012

    5 medicated IUIs w/ RE (March - July 2013) = BFN

    Fresh IVF Cycle in September 2013 resulted in 18 mature eggs, 16 fertilized, 12 made it to day 5. Transfer of 2 Grade A blastocysts on 9/15/13, and 10 embryos in the freezer!      *****BFP on 9/25/13 - betas: @10dp5dt = 232; @12dp5dt = 465; @15dp5dt = 1,581   *********William George born June 4, 2014*********
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    So exciting!!! I will be thinking about you all weekend and keeping my fingers crossed for Sunday's transfer!! :-)
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    That's an amazing outcome! How exciting. And your doc/RE will guide you to best choice for the best outcome! Good luck on Sunday! The ET part is a snap :)
    Lil'mamaz was born on Aug 21, 2014! She's PERFECT!

    It's been a long road to here...
    Me (43) and J (45) - same sex couple. And we don't feel 40+!
    June'12 - First RE Visit
    Sept. '12 - Tubes removed
    Dec. '12 - Donor Egg/Donor Sperm IVF Cycle - 4 good embies!
    Dec. '12 - Fresh transfer, BFP! EDD 8/29/13
    Mar. '13 - Missed m/c at 16w1d, baby boy stopped growing at 15w4d
    Loss due to umbilical cord clot...baby was perfect. :(
    Jul '13 - FET#1 - c/p
    Sept. '13 - FET#2 - BFN
    Dec.' 2, 2013 - FET#3 with our last chance embie - BFP!!!
    Dec' 26, 2013 - hb!!
    EDD 8/20/14 with a baby girl!
    Little S was born on 8/21/14 - 8lb, 14 oz and 20 inches long.
    We live in Seattle and used SRM for our donor egg IVF cycle


    imageimageimageimage

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    @KH826, how are you feeling?  I just wanted to let you know that I started feeling worse (sore, uncomfortable, bloated) after ER and leading up to ET.  I started to worry that I was getting OHSS and they would have to cancel my ET -- and then lo and behold, the morning of ET I woke up feeling 100% fine.  So I hope you're feeling OK, but if you're not, it's likely normal (of course if you started developing telltale signs of OHSS or anything your RE told you to watch out for, that warrants a phone call).  Hope you're comfortable and getting excited about tomorrow!  You'll be PUPO before you know it.
    Married my wife 8/2007 ~ TTC #1 since 7/2011
    9 IUIs = 9 BFNs
    IVF October 2012: 22 eggs retrieved, 17 fertilized, 5 frozen
    ET #1: 1 blast = BFP; Blighted ovum discovered at 7w5d; D&E
    FET #1: 1 blast = BFP; Missed m/c discovered at 9w5d; D&E
    Karyotyping: normal ~ RPL Testing: normal ~ Hysteroscopy: normal
    FET #2: 1 blast transferred 10/25; BFP 10/31!
    EDD 7/13/14 ~ Induced at 37w4d due to pre-eclampsia ~ Born on 6/28/14
    *Everyone welcome*

    Baby Birthday Ticker Ticker
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    Thanks, ball.and.chain - I actually feel fine, no signs of OHSS, so I think I have mostly been lucky with that. I am just feeling really tired, but that's all... I think that is from the progesterone injections... I'm planning to mostly lay low today. Feeling excited!!! :)

    Me - 30, My wife - 31 , Together for 10 yrs - Married August 2012

    5 medicated IUIs w/ RE (March - July 2013) = BFN

    Fresh IVF Cycle in September 2013 resulted in 18 mature eggs, 16 fertilized, 12 made it to day 5. Transfer of 2 Grade A blastocysts on 9/15/13, and 10 embryos in the freezer!      *****BFP on 9/25/13 - betas: @10dp5dt = 232; @12dp5dt = 465; @15dp5dt = 1,581   *********William George born June 4, 2014*********
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    @kh826 thank goodness you are feeling well. Excited to hear tomorrows update!!
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    Progesterone in any form makes you feel like crap! Hang in there!!!
    Lil'mamaz was born on Aug 21, 2014! She's PERFECT!

    It's been a long road to here...
    Me (43) and J (45) - same sex couple. And we don't feel 40+!
    June'12 - First RE Visit
    Sept. '12 - Tubes removed
    Dec. '12 - Donor Egg/Donor Sperm IVF Cycle - 4 good embies!
    Dec. '12 - Fresh transfer, BFP! EDD 8/29/13
    Mar. '13 - Missed m/c at 16w1d, baby boy stopped growing at 15w4d
    Loss due to umbilical cord clot...baby was perfect. :(
    Jul '13 - FET#1 - c/p
    Sept. '13 - FET#2 - BFN
    Dec.' 2, 2013 - FET#3 with our last chance embie - BFP!!!
    Dec' 26, 2013 - hb!!
    EDD 8/20/14 with a baby girl!
    Little S was born on 8/21/14 - 8lb, 14 oz and 20 inches long.
    We live in Seattle and used SRM for our donor egg IVF cycle


    imageimageimageimage

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    WOW! That is quite a brood you will have there! Congrats :)
    Lil'mamaz was born on Aug 21, 2014! She's PERFECT!

    It's been a long road to here...
    Me (43) and J (45) - same sex couple. And we don't feel 40+!
    June'12 - First RE Visit
    Sept. '12 - Tubes removed
    Dec. '12 - Donor Egg/Donor Sperm IVF Cycle - 4 good embies!
    Dec. '12 - Fresh transfer, BFP! EDD 8/29/13
    Mar. '13 - Missed m/c at 16w1d, baby boy stopped growing at 15w4d
    Loss due to umbilical cord clot...baby was perfect. :(
    Jul '13 - FET#1 - c/p
    Sept. '13 - FET#2 - BFN
    Dec.' 2, 2013 - FET#3 with our last chance embie - BFP!!!
    Dec' 26, 2013 - hb!!
    EDD 8/20/14 with a baby girl!
    Little S was born on 8/21/14 - 8lb, 14 oz and 20 inches long.
    We live in Seattle and used SRM for our donor egg IVF cycle


    imageimageimageimage

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    So excited for you! I hope all goes well tomorrow!

    Me: 30  DW (aka C): 29

    Together since 2/15/11 ~ Legally married in NY on 9/29/12

    ***CP mentioned***

    We've been working on baby #1 since July 2013 using Open ID donor sperm.  8 IUI attempts with 5 actual IUIs and one chemical pregnancy.  We have one fresh IVF cycle under our belts as well as a FET.  I have endometriosis and a uterine septum that was corrected via surgery in November 2013. 

    11/14/14 -  Second HSG shows that tubes are still clear and ute is looking good. 

    12/6/14 - Started BCPs in prep for IVF #2

    12/22/14 - Saline u/s and endometrial scratch (All was clear and OUCH!)

    1/2/15 - Began stimming for IVF #2

     ****All Welcome!****

    We are Mommas to four fur babies - 3 dogs and 1 cat.

    image   

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    So excited for you!

    TTC our first. Married to, and madly in love with, my beautiful wife. Living with our fur baby and enjoying 19 nieces and nephews. 
    • DW and I have been tracking, preparing, getting medical testing since January 2013.
    • First Cycle: Unmedicated ICI w/ Donor Sperm 08/02/13: BFN
    • Second Cycle: Unmedicated ICI w/ Donor Sperm 09/11/13, 09/13/13, 09/15/13: BFN
    • Third Cycle: Unmedicated ICI w/ Donor Sperm: 10/13/13, 10/15/13, 10/17/13, 10/21/13: BFN
    • January 2014: Sonohysterogram shows excellent lining & tubes have no blockages
    • Fourth Cycle:  Monitored clomid cycle  w/ ICI's at home: 1/24/14 and 1/25/14. Ovulation verified:  BFN
    • Fifth Cycle: 02/2014 Femara 5mg with ovidrel trigger CD14: BFN
    • Taking a few months off to evaluate if we want to keep trying


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    image
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    Thinking of you today, @KH826!
    Baby Birthday Ticker Ticker
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    Same here! Hope you have great embryos today and that the ET goes smoothly!
    ****loss discussed*****

    We're queer. I'm 33, have severe stage 4 endo, and had both fallopian tubes removed. My love ("Manada" on the boards, 32) was diagnosed with diminished ovarian reserve. We did Partner IVF (my eggs, her uterus). We lost our twins Tavin and Casey at 21 weeks gestation.

    Our IUIs
    with @Manada: IUI# 1-7 (December 2012- September 2013) all BFN. Tried natural, femara, clomid, puregon/follistim, clomid and menopur combo, both the ovidrel and HCG triggers.

    Our IVFs:
    IVF #1 my eggs November/December 2013: Cancelled IVF due to poor response

    IVF #2 my eggs/Manada's uterus January/February 2014
    BCPs and lupron overlap Stimmed: 1/22-2/2: Bravelle and Menopur (dosage ranged from B300 and M150 to B375 and M150 to B300 and M225)
    2/4 retrieved 10 eggs. Endo was much worse than expected. Only 3 eggs fertilized; February 7 transferred two day 3 embryos, froze one. All great condition.
    BFP eve of 6dp3dt; Beta 1 (11dp3dt): 110; Beta 2 (13dp3dt): 175; Beta 3 (15dp3dt): 348; Beta 4 (19dp3dt): 2222; Beta 5 (21dp3dt): 4255
    1st ultrasound (3/6  6w 1d): TWINS!!!! Twin A measuring 6w1d with a heartbeat of 118bpm. Twin B measuring 6w0d with a heartbeat of 113bpm. 

    ***July 18, 2014 we lost our beautiful babies at 21 weeks gestation. They were born too early. Tavin Sara T. and Casey Elizabeth T. are beautiful and precious and we will love them and miss them forever.***

    FET #1 December 2014
    Intralipid infusion on Dec 10. Transfer of 1 day 3 nine-cell embryo into my uterus on Dec. 19. (acupuncture immediately before and after)
    BFP on Dec. 27; Beta 1 Jan 2 (14dp3dt): 665, Beta 2 Jan 4 (16dp3dt): 1859, Beta 3 Jan 6 (18dp3dt): 4449, Beta 4 Jan 10 (22dp3dt): 12,251.



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